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Metformin hijacks AMPK-ERK1/2 signaling to trigger a pathogenic “selection trap” and thymic atrophy

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1. scibot 25 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116762
  
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sciencedirect.com/science/article/pii/S2211124725015347
Sep 2025
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E. coli-activated cellular circuit restrains intestinal inflammatory microbiota-specific T cells and protects against colitis

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1. scibot 24 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116332
  
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sciencedirect.com/science/article/pii/S2211124725011039
Aug 2025
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Nrf2 drives activation-driven expansion of CD4+T cells by modulating glucose and glutamine metabolism

1
1. scibot 26 Aug 2025
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.celrep.2025.116177
  
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sciencedirect.com/science/article/pii/S2211124725009489
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Developmental epigenetic programming by Tet1/3 determines peripheral CD8 T cell fate

1
1. scibot 11 Jun 2025
  
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  RRID:AB_1257209
  
  DOI: 10.1038/s44319-025-00439-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12116802/
Apr 2025
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Soluble CTLA-4 regulates immune homeostasis and promotes resolution of inflammation by suppressing type 1 but allowing type 2 immunity

1
1. scibot 01 Apr 2025
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.immuni.2025.03.004
  
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sciencedirect.com/science/article/pii/S1074761325001232
Mar 2025
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DAP12-associated synthetic antigen receptors enable multi-targeting of T cells with independent chimeric receptors in a small genetic payload

1
1. scibot 20 Mar 2025
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.isci.2025.112142
  
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sciencedirect.com/science/article/pii/S258900422500402X
Dec 2024
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A double-edged sword role of IFN-γ producing iNKT cells in sepsis: persistent suppression of Treg cell formation in a Nr4a1 dependent manner

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1. scibot 14 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111462
  
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sciencedirect.com/science/article/pii/S2589004224026890
Sep 2024
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The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells

1
1. scibot 25 Sep 2024
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.celrep.2019.11.089
  
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  Curator: @ethanbadger
  
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  RRID:AB_1257209 RRID:AB_1257210 RRIDCUR:Incorrect
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sciencedirect.com/science/article/pii/S2211124719315876
Jul 2024
www.cell.com www.cell.com

BTLA and PD-1 signals attenuate TCR-mediated transcriptomic changes

1
1. scibot 18 Jul 2024
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.isci.2024.110253
  
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cell.com/iscience/abstract/S2589-0042(24)01478-0
Jun 2024
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NR4A1 transcriptionally regulates the differentiation of stem-like CD8+ T cells in the tumor microenvironment

1
1. scibot 04 Jun 2024
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.celrep.2024.114301
  
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sciencedirect.com/science/article/pii/S2211124724006296
Mar 2024
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Tonic TCR and IL-1β signaling mediate phenotypic alterations of naive CD4+ T cells

2
1. scibot 19 Mar 2024
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.celrep.2024.113954
  
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2. scibot 19 Mar 2024
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.celrep.2024.113954
  
  Resource: (Thermo Fisher Scientific Cat# 12-5965-82, RRID:AB_1257209)
  
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sciencedirect.com/science/article/pii/S2211124724002821
Jun 2023
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Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses

1
1. scibot 23 Jun 2023
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.immuni.2023.05.011
  
  Resource: (Thermo Fisher Scientific Cat# 12-5965-82, RRID:AB_1257209)
  
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sciencedirect.com/science/article/pii/S1074761323002285
Jul 2022
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T-bet+ B cells accumulate in adipose tissue and exacerbate metabolic disorder during obesity

1
1. scibot 27 Jul 2022
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.cmet.2022.07.002
  
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sciencedirect.com/science/article/pii/S1550413122003011
May 2022
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Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression

1
1. scibot 12 May 2022
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.celrep.2022.110766
  
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sciencedirect.com/science/article/pii/S2211124722005307
Jan 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua

1
1. scibot 07 Jan 2022
  
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  RRID:AB_1257209
  
  DOI: 10.7554/eLife.71769
  
  Resource: (Thermo Fisher Scientific Cat# 12-5965-82, RRID:AB_1257209)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8700290/
Nov 2021
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MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function

1
1. scibot 12 Nov 2021
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.immuni.2021.10.011
  
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sciencedirect.com/science/article/pii/S1074761321004489
Sep 2021
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Brief homogeneous TCR signals instruct common iNKT progenitors whose effector diversification is characterized by subsequent cytokine signaling

1
1. scibot 25 Sep 2021
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.immuni.2021.09.003
  
  Resource: (Thermo Fisher Scientific Cat# 12-5965-82, RRID:AB_1257209)
  
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sciencedirect.com/science/article/pii/S1074761321003666
Aug 2021
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IL-15 enhances CCR5-mediated migration of memory CD8+ T cells by upregulating CCR5 expression in the absence of TCR stimulation

1
1. scibot 14 Aug 2021
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.celrep.2021.109438
  
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sciencedirect.com/science/article/pii/S221112472100855X
Jul 2021
www.nature.com www.nature.com

Locoregional infusion of HER2-specific CAR T cells in children and young adults with recurrent or refractory CNS tumors: an interim analysis

1
1. scibot 21 Jul 2021
  
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  RRID:AB_1257209
  
  DOI: 10.1038/s41591-021-01404-8
  
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nature.com/articles/s41591-021-01404-8
May 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

T cell self-reactivity during thymic development dictates the timing of positive selection

1
1. scibot 19 May 2021
  
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  RRID:AB_1257209
  
  DOI: 10.7554/eLife.65435
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8116051/
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An Integrated Epigenomic and Transcriptomic Map of Mouse and Human αβ T Cell Development

1
1. scibot 07 May 2021
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.immuni.2020.10.024
  
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sciencedirect.com/science/article/pii/S1074761320304659
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inducible mechanisms of disease tolerance provide an alternative strategy of acquired immunity to malaria

1
1. scibot 28 Mar 2021
  
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  RRID:AB_1257209
  
  DOI: 10.7554/eLife.63838
  
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  Curator: @evieth
  
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  RRID:AB_1257209 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7987336/
Dec 2020
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The Methyltransferase DOT1L Controls Activation and Lineage Integrity in CD4+ T Cells during Infection and Inflammation

1
1. scibot 17 Dec 2020
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.celrep.2020.108505
  
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  RRIDCUR:Validated RRID:AB_1257209
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sciencedirect.com/science/article/pii/S2211124720314947
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_1257209
  
  DOI: 10.1016/j.celrep.2018.12.078
  
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  Curator: @ethanbadger
  
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  RRID:AB_1257209 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124718320230
Nov 2018
www-sciencedirect-com.ezproxy.is.ed.ac.uk www-sciencedirect-com.ezproxy.is.ed.ac.uk

CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity

1
1. scibot 05 Nov 2018
  
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  Curator: @Jmenke
  
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  RRID:AB_1257209 RRIDCUR:Validated
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www-sciencedirect-com.ezproxy.is.ed.ac.uk/science/article/pii/S107476131830342X