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Salicylic acid engages central metabolic regulators SnRK1 and TOR to govern immunity by differential phosphorylation of NPR1

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1. scibot 01 Oct 2026
  
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  DOI: 10.1016/j.cell.2026.09.011
  
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sciencedirect.com/science/article/pii/S0092867426010809
Jul 2026
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Structures of dynamic interactors at native proteasomes by PhIX-MS and cryo-electron microscopy

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1. scibot 23 Jul 2026
  
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  DOI: 10.1016/j.molcel.2026.06.032
  
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NSUN2 integrates glucose and one‑carbon metabolism upstream of Rag GTPase-dependent mTORC1 signaling

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1. scibot 12 Jul 2026
  
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  DOI: 10.1016/j.cellsig.2026.112734
  
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Jun 2026
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NSUN2-mediated m5C modification of BHLF1 RNA facilitates the lytic replication of Epstein-Barr virus

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1. scibot 22 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117562
  
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Mar 2026
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Poxvirus dsDNA genomes differentially activate AIM2 or NLRP3 inflammasomes in human primary cells

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1. scibot 06 Mar 2026
  
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  DOI: 10.1038/s44318-025-00690-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12953764/
Nov 2025
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HSP90 buffers deleterious genetic variations in BRCA1

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1. scibot 22 Nov 2025
  
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sciencedirect.com/science/article/pii/S1097276525008676
Oct 2025
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Nuclear U1 snRNA facilitates the dimerization of hnRNPA2B1 to enhance anti-DNA viral innate immunity

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1. scibot 23 Oct 2025
  
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sciencedirect.com/science/article/pii/S2211124725012331
Jul 2025
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An alternate receptor for adeno-associated viruses

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  DOI: 10.1016/j.cell.2025.06.026
  
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sciencedirect.com/science/article/pii/S0092867425006920
Jun 2025
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RIPK4 promotes epidermal differentiation through phase separation and activation of LATS1/2

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.devcel.2025.05.017
  
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sciencedirect.com/science/article/pii/S1534580725003284
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Zmym2 Alters Expression of Key Craniofacial Genes

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1. scibot 11 Jun 2025
  
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  DOI: 10.1002/dvg.70018
  
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onlinelibrary.wiley.com/doi/10.1002/dvg.70018
May 2025
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Investigation of Fibrillar Aggregates Formed by Pathogenic Pre-pro-vasopressin Mutants that Cause ADNDI

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1. scibot 21 May 2025
  
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  DOI: 10.1210/clinem/dgae749
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12086421/
Mar 2025
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Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs

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1. scibot 20 Mar 2025
  
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sciencedirect.com/science/article/pii/S0092867425001990
Feb 2025
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Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3

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1. scibot 04 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115250
  
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Jan 2025
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Transketolase attenuates the chemotherapy sensitivity of glioma cells by modulating R-loop formation

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1. scibot 14 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115142
  
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The de novo synthesis of GABA and its gene regulatory function control hepatocellular carcinoma metastasis

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.devcel.2024.12.007
  
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sciencedirect.com/science/article/pii/S1534580724007299
Oct 2024
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Stress triggers irritable bowel syndrome with diarrhea through a spermidine-mediated decline in type I interferon

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1. scibot 04 Oct 2024
  
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  DOI: 10.1016/j.cmet.2024.09.002
  
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sciencedirect.com/science/article/pii/S1550413124003668
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Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application

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1. scibot 02 Oct 2024
  
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  DOI: 10.1038/s41467-024-52110-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11427689/
Jun 2024
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eIF4F complex dynamics are important for the activation of the integrated stress response

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1. scibot 30 Jun 2024
  
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  DOI: 10.1016/j.molcel.2024.04.016
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11189614/
May 2024
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TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks

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1. scibot 21 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114214
  
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sciencedirect.com/science/article/pii/S2211124724005424
Mar 2024
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Housekeeping U1 snRNA facilitates antiviral innate immunity by promoting TRIM25-mediated RIG-I activation

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  DOI: 10.1016/j.celrep.2024.113945
  
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IκBζ is a dual-use coactivator of NF-κB and POU transcription factors

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Jan 2024
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WNT4 Regulates Cellular Metabolism via Intracellular Activity at the Mitochondria in Breast and Gynecologic Cancers

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1. scibot 19 Jan 2024
  
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  DOI: 10.1158/2767-9764.CRC-23-0275
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10793200/
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OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB

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  DOI: 10.1016/j.molcel.2023.11.042
  
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sciencedirect.com/science/article/pii/S1097276523010195
Oct 2023
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Zmym4 is required for early cranial gene expression and craniofacial cartilage formation

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1. scibot 20 Oct 2023
  
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  DOI: 10.3389/fcell.2023.1274788
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10579616/
Sep 2023
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Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis

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  DOI: 10.1016/j.chom.2023.08.003
  
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sciencedirect.com/science/article/pii/S1931312823003281
Jul 2023
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Sen1 and Rrm3 ensure permissive topological conditions for replication termination

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  DOI: 10.1016/j.celrep.2023.112747
  
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May 2023
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Exercise-derived peptide protects against pathological cardiac remodeling

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  DOI: 10.1016/j.ebiom.2022.104164
  
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sciencedirect.com/science/article/pii/S2352396422003450
Feb 2023
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Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein

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RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex

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  DOI: 10.1016/j.celrep.2023.112097
  
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Nov 2022
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Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha

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  DOI: 10.1016/j.molcel.2022.10.030
  
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P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection

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1. scibot 04 Nov 2022
  
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  DOI: 10.1084/jem.20220837
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9623368/
Oct 2022
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ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins

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1. scibot 25 Oct 2022
  
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  DOI: 10.1016/j.molcel.2022.09.035
  
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Feb 2022
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LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland

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1. scibot 16 Feb 2022
  
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  DOI: 10.1016/j.celrep.2022.110375
  
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Dual Sensing of Physiologic pH and Calcium by EFCAB9 Regulates Sperm Motility

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1. scibot 04 Feb 2022
  
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  DOI: 10.1016/j.cell.2019.03.047
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8808721/
Aug 2021
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A calmodulin-binding transcription factor links calcium signaling to antiviral RNAi defense in plants

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1. scibot 06 Aug 2021
  
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  DOI: 10.1016/j.chom.2021.07.003
  
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sciencedirect.com/science/article/pii/S1931312821003048
Jul 2021
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NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25

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1. scibot 28 Jul 2021
  
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  RRID:AB_1264166
  
  DOI: 10.1016/j.chom.2019.02.013
  
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Mar 2021
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Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape

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1. scibot 13 Mar 2021
  
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  RRID:AB_1264166
  
  DOI: 10.1126/science.abe6230
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7932109/
Dec 2020
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The Nucleosome Remodeling and Deacetylase Complex Has an Asymmetric, Dynamic, and Modular Architecture

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  DOI: 10.1016/j.celrep.2020.108450
  
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Sep 2020
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SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP

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  RRID:AB_1264166
  
  DOI: 10.1016/j.celrep.2020.107640
  
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Jan 2020
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STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production

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  RRID:AB_1264166
  
  DOI: 10.1016/j.celrep.2019.09.069
  
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Aryl Sulfonamides Degrade RBM39 and RBM23 by Recruitment to CRL4-DCAF15

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  RRID:AB_1264166
  
  DOI: 10.1016/j.celrep.2019.09.079
  
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Untitled document

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  RRID:AB_1264166
  
  DOI: 10.1016/j.ccell.2019.01.009
  
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Untitled document

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  RRID:AB_1264166
  
  DOI: 10.1016/j.cell.2019.03.047
  
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