66 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma
    1
    1. scibot 11 Nov 2024
      AB:1310784

      DOI: 10.1016/j.devcel.2024.10.009

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    sciencedirect.com/science/article/pii/S1534580724006282
  3. Aug 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Neuroepithelial bodies and terminal bronchioles are niches for distinctive club cells that repair the airways following acute notch inhibition
    1
    1. scibot 27 Aug 2024
      AB_1310784

      DOI: 10.1016/j.celrep.2024.114654

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    sciencedirect.com/science/article/pii/S2211124724010052
  5. www.biorxiv.org www.biorxiv.org
    Functional mapping of epigenetic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes
    1
    1. scibot 25 Aug 2024
      RRID:AB_1310784

      DOI: 10.1101/2024.08.19.607671

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    biorxiv.org/content/10.1101/2024.08.19.607671v1
  6. May 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell lung cancer
    1
    1. scibot 24 May 2024
      RRID:AB_1310784

      DOI: 10.1016/j.ccell.2024.05.003

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    sciencedirect.com/science/article/pii/S1535610824001648
  8. Apr 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of human alveolar epithelial type I cells from pluripotent stem cells
    2
    1. scibot 23 Apr 2024
      RRID:AB_1310784

      DOI: 10.1016/j.stem.2024.03.017

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    2. scibot 23 Apr 2024
      RRID:AB_1310784

      DOI: 10.1016/j.stem.2024.03.017

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    ncbi.nlm.nih.gov/pmc/articles/PMC11147407/
  10. Feb 2024
  11. 52.53.155.43 52.53.155.43
    A dynamic Hedgehog gradient orients tracheal cartilage rings
    2
    1. scibot 23 Feb 2024
      RRID:AB_1310784

      DOI: 10.1101/2023.09.25.559425

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    2. scibot 22 Feb 2024
      RRID:AB_1310784

      DOI: 10.1101/2023.09.25.559425

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    52.53.155.43/d688c17bc0086722329b4eeab0b2ce686ae1cf6e/2023.09.25.559425v1.full-html.html
  12. Jan 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Deep spatial proteomics reveals region-specific features of severe COVID-19-related pulmonary injury
    1
    1. scibot 19 Jan 2024
      RRID:AB_1310784

      DOI: 10.1016/j.celrep.2024.113689

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    sciencedirect.com/science/article/pii/S2211124724000172
  14. www.sciencedirect.com www.sciencedirect.com
    Patterning ganglionic eminences in developing human brain organoids using a morphogen-gradient-inducing device
    1
    1. scibot 19 Jan 2024
      RRID:AB_1310784

      DOI: 10.1016/j.crmeth.2023.100689

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    sciencedirect.com/science/article/pii/S2667237523003752
  15. www.sciencedirect.com www.sciencedirect.com
    Human fetal brain self-organizes into long-term expanding organoids
    1
    1. scibot 09 Jan 2024
      RRID:AB_1310784

      DOI: 10.1016/j.cell.2023.12.012

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    sciencedirect.com/science/article/pii/S0092867423013442
  16. Oct 2023
  17. www.sciencedirect.com www.sciencedirect.com
    In vitro vascularized immunocompetent patient-derived model to test cancer therapies
    1
    1. scibot 14 Oct 2023
      RRID:AB_1310784

      DOI: 10.1016/j.isci.2023.108094

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    sciencedirect.com/science/article/pii/S2589004223021715
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of Neural Fate by Combination of BMP Blockade and Chromatin Modification
    1
    1. scibot 06 Oct 2023
      RRID:AB_1310784

      DOI: 10.1016/j.isci.2023.107887

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    ncbi.nlm.nih.gov/pmc/articles/PMC10522999/
  19. Aug 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Durable alveolar engraftment of PSC-derived lung epithelial cells into immunocompetent mice
    1
    1. scibot 25 Aug 2023
      RRID:AB_1310784

      DOI: 10.1016/j.stem.2023.07.016

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    sciencedirect.com/science/article/pii/S1934590923002837
  21. www.sciencedirect.com www.sciencedirect.com
    Airway stem cell reconstitution by the transplantation of primary or pluripotent stem cell-derived basal cells
    1
    1. scibot 25 Aug 2023
      RRID:AB_1310784

      DOI: 10.1016/j.stem.2023.07.014

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    sciencedirect.com/science/article/pii/S1934590923002813
  22. Jul 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Profiling transcriptomic responses of human stem cell-derived medium spiny neuron-like cells to exogenous phasic and tonic neurotransmitters
    1
    1. scibot 04 Jul 2023
      AB_1310784

      DOI: 10.1016/j.mcn.2023.103876

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    sciencedirect.com/science/article/pii/S1044743123000702
  24. Jun 2023
  25. aacrjournals.org aacrjournals.org
    RBM10 loss promotes EGFR-driven lung cancer and confers sensitivity to spliceosome inhibition
    1
    1. scibot 03 Jun 2023
      RRID:AB_1310784

      DOI: 10.1158/0008-5472.CAN-22-1549

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    aacrjournals.org/cancerres/article/83/9/1490/726058/RBM10-Loss-Promotes-EGFR-Driven-Lung-Cancer-and
  26. May 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atf3 defines a population of pulmonary endothelial cells essential for lung regeneration
    1
    1. scibot 31 May 2023
      RRID:AB_1310784

      DOI: 10.7554/eLife.83835

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    ncbi.nlm.nih.gov/pmc/articles/PMC10219650/
  28. www.nature.com www.nature.com
    A prime editor mouse to model a broad spectrum of somatic mutations in vivo
    1
    1. scibot 13 May 2023
      RRID:AB_1310784

      DOI: 10.1038/s41587-023-01783-y

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    nature.com/articles/s41587-023-01783-y
  29. Apr 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer
    1
    1. scibot 26 Apr 2023
      RRID:AB_1310784

      DOI: 10.1016/j.ccell.2023.03.019

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    sciencedirect.com/science/article/pii/S1535610823000922
  31. Mar 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Genotype-phenotype mapping of a patient-derived lung cancer organoid biobank identifies NKX2-1-defined Wnt dependency in lung adenocarcinoma
    1
    1. scibot 11 Mar 2023
      RRID:AB_1310784

      DOI: 10.1016/j.celrep.2023.112212

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    sciencedirect.com/science/article/pii/S2211124723002231
  33. Feb 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Generation of telomeric repeat binding factor 1 (TRF1)-knockout human embryonic stem cell lines, KRIBBe010-A-95, KRIBBe010-A-96, and KRIBBe010-A-97, using CRISPR/Cas9 technology
    1
    1. scibot 16 Feb 2023
      RRID:AB_1310784

      DOI: 10.1016/j.scr.2023.103045

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    sciencedirect.com/science/article/pii/S1873506123000314
  35. Dec 2022
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis
    1
    1. scibot 30 Dec 2022
      RRID:AB_1310784

      DOI: 10.1158/0008-5472.CAN-21-3214

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    ncbi.nlm.nih.gov/pmc/articles/PMC9664136/
  37. Aug 2022
  38. academic.oup.com academic.oup.com
    Murine thyroid IL-4 expression worsens hypothyroidism under iodine restriction and mitigates Graves’ disease development
    1
    1. scibot 17 Aug 2022
      RRID:AB_1310784

      DOI: 10.1210/endocr/bqac107

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    academic.oup.com/endo/article/163/9/bqac107/6650252
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Smarca4 inactivation promotes lineage-specific transformation and early metastatic features in the lung
    1
    1. scibot 04 Aug 2022
      RRID:AB_1310784

      DOI: 10.1158/2159-8290.CD-21-0248

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    ncbi.nlm.nih.gov/pmc/articles/PMC8831463/
  40. Jul 2022
  41. www.sciencedirect.com www.sciencedirect.com
    FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma
    1
    1. scibot 15 Jul 2022
      RRID:AB_1310784

      DOI: 10.1016/j.devcel.2022.06.017

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    sciencedirect.com/science/article/pii/S1534580722004580
  42. www.sciencedirect.com www.sciencedirect.com
    Klf5 defines alveolar epithelial type 1 cell lineage commitment during lung development and regeneration
    1
    1. scibot 08 Jul 2022
      RRID:AB_1310784

      DOI: 10.1016/j.devcel.2022.06.007

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    sciencedirect.com/science/article/pii/S1534580722004476
  43. Jun 2022
  44. www.sciencedirect.com www.sciencedirect.com
    R-SPONDIN2+ mesenchymal cells form the bud tip progenitor niche during human lung development
    1
    1. scibot 09 Jun 2022
      RRID:AB_1310784

      DOI: 10.1016/j.devcel.2022.05.010

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    sciencedirect.com/science/article/pii/S1534580722003677
  45. May 2022
  46. www.sciencedirect.com www.sciencedirect.com
    A versatile viral toolkit for functional discovery in the nervous system
    1
    1. scibot 27 May 2022
      RRID:AB_1310784

      DOI: 10.1016/j.crmeth.2022.100225

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    sciencedirect.com/science/article/pii/S2667237522000881
  47. www.mdpi.com www.mdpi.com
    EMT, Stemness, and Drug Resistance in Biological Context: A 3D Tumor Tissue/In Silico Platform for Analysis of Combinatorial Treatment in NSCLC with Aggressive KRAS-Biomarker Signatures
    1
    1. scibot 10 May 2022
      RRID:AB_1310784

      DOI: 10.3390/cancers14092176

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    mdpi.com/2072-6694/14/9/2176
  48. Feb 2022
  49. elifesciences.org elifesciences.org
    Recapitulating human cardio-pulmonary co-development using simultaneous multilineage differentiation of pluripotent stem cells
    1
    1. scibot 19 Feb 2022
      RRID:AB_1310784

      DOI: 10.7554/eLife.67872

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    elifesciences.org/articles/67872
  50. Jan 2022
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A functional taxonomy of tumor suppression in oncogenic KRAS-driven lung cancer
    1
    1. scibot 05 Jan 2022
      RRID:AB_1310784

      DOI: 10.1158/2159-8290.CD-20-1325

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    ncbi.nlm.nih.gov/pmc/articles/PMC8292166/
  52. Nov 2021
  53. elifesciences.org elifesciences.org
    A functional genetic toolbox for human tissue-derived organoids
    1
    1. scibot 05 Nov 2021
      RRID:AB_1310784

      DOI: 10.7554/eLife.67886

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    elifesciences.org/articles/67886
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma
    1
    1. scibot 05 Nov 2021
      RRID:AB_1310784

      DOI: 10.7554/eLife.71596

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    ncbi.nlm.nih.gov/pmc/articles/PMC8553340/
  55. Oct 2021
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NMDARs Drive the Expression of Neuropsychiatric Disorder Risk Genes Within GABAergic Interneuron Subtypes in the Juvenile Brain
    1
    1. scibot 13 Oct 2021
      RRID:AB_1310784

      DOI: 10.3389/fnmol.2021.712609

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    ncbi.nlm.nih.gov/pmc/articles/PMC8500094/
  57. Sep 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease
    1
    1. scibot 01 Sep 2021
      RRID:AB_1310784

      DOI: 10.1016/j.celrep.2021.109636

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    sciencedirect.com/science/article/pii/S2211124721010792
  59. Jul 2021
  60. cercor.oxfordjournals.org cercor.oxfordjournals.org
    The Role of Sonic Hedgehog in the Specification of Human Cortical Progenitors In Vitro
    2
    1. scibot 27 Jul 2021
      rabbit monoclonal anti-Nkx2.1

      DOI: 10.1093/cercor/bhu183

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    2. scibot 27 Jul 2021
      monoclonal rabbit anti-Nkx2.1

      DOI: 10.1093/cercor/bhu183

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    cercor.oxfordjournals.org/content/26/1/131.long
  61. www.sciencedirect.com www.sciencedirect.com
    Differentiation of human pluripotent stem cells into functional airway basal stem cells
    1
    1. scibot 22 Jul 2021
      RRID:AB_1310784

      DOI: 10.1016/j.xpro.2021.100683

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    sciencedirect.com/science/article/pii/S2666166721003907
  62. www.sciencedirect.com www.sciencedirect.com
    Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis
    1
    1. scibot 14 Jul 2021
      RRID:AB_1310784

      DOI: 10.1016/j.celrep.2021.109347

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    sciencedirect.com/science/article/pii/S2211124721007233
  63. May 2021
  64. www.sciencedirect.com www.sciencedirect.com
    Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells
    1
    1. scibot 09 May 2021
      RRID:AB_1310784

      DOI: 10.1016/j.stem.2020.09.017

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    Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells
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  66. Apr 2021
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    Airway basal stem cells generate distinct subpopulations of PNECs
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    Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma
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  69. www.sciencedirect.com www.sciencedirect.com
    Generation of human pluripotent stem cell-derived fused organoids with oligodendroglia and myelin
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  70. Nov 2020
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    Imbalance of Excitatory/Inhibitory Neuron Differentiation in Neurodevelopmental Disorders with an NR2F1 Point Mutation
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction
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  73. Sep 2020
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    Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer
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    In Vitro and In Vivo Development of the Human Airway at Single-Cell Resolution
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    MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate
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  77. www.nature.com www.nature.com
    Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells
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      DOI: 10.1038/s41596-019-0220-0

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    Multi-lineage Lung Regeneration by Stem Cell Transplantation across Major Genetic Barriers
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    Generation of Lungs by Blastocyst Complementation in Apneumic Fgf10-Deficient Mice
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  80. Jan 2020
  81. elifesciences.org elifesciences.org
    Mutationally-activated PI3’-kinase-α promotes de-differentiation of lung tumors initiated by the BRAFV600E oncoprotein kinase
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      DOI: 10.7554/eLife.43668

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    BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer
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      DOI: 10.7554/eLife.38579

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  84. www.sciencedirect.com www.sciencedirect.com
    OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome
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  85. Nov 2018
  86. www.sciencedirect.com www.sciencedirect.com
    Chd2 Is Necessary for Neural Circuit Development and Long-Term Memory
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    The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
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    Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification
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  89. www.sciencedirect.com www.sciencedirect.com
    3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
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  91. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S1534580718301588
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    Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity
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  94. Nov 2017
  95. elifesciences.org elifesciences.org
    Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids
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