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    Hyperactive mTORC1 Disrupts Habenula Function and Light Preference in Zebrafish Model of Tuberous Sclerosis Complex
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    Bnip3 expression is strongly associated with reelin-positive entorhinal cortex layer II neurons
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    Nucleolar Localization of the RNA Helicase DDX21 Predicts Survival Outcomes in Gynecologic Cancers
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    Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule
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    Electron transport chain inhibition increases cellular dependence on purine transport and salvage
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    P2X7 receptor antagonism by AZ10606120 significantly depletes glioblastoma cancer stem cells in vitro
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    Tumour microenvironment programming by an RNA–RNA-binding protein complex creates a druggable vulnerability in IDH-wild-type glioblastoma
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    Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice
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    Behavioral and cortical arousal from sleep, muscimol-induced coma, and anesthesia by direct optogenetic stimulation of cortical neurons
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    Substrate mechanics unveil early structural and functional pathology in iPSC micro-tissue models of hypertrophic cardiomyopathy
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    Testosterone deficiency promotes arterial stiffening independent of sex chromosome complement
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    Generation and characterization of a Stargardt’s disease-specific induced pluripotent stem cell line (LVPEIi008-A) with a homozygous missense mutation in exon 44 of ABCA4
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    GABAergic neurons of anterior thalamic reticular nucleus regulate states of consciousness in propofol‐ and isoflurane‐mediated general anesthesia
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    Reversion from basal histone H4 hypoacetylation at the replication fork increases DNA damage in FANCA deficient cells
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    Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress
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    FAK regulates tension transmission to the nucleus and endothelial transcriptome independent of kinase activity
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    Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity
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    Polyvalent mpox mRNA vaccines elicit robust immune responses and confer potent protection against vaccinia virus
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    MicroRNA-29b-3p degenerates terminally differentiated dopaminergic SH-SY5Y cells by perturbation of mitochondrial functions
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    Intracellular Retention of Estradiol is Augmented by GRAM Domain Containing Protein ASTER-B in Breast Cancer Cells
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    PKCð regulates chromatin remodeling and DNA repair through SIRT6
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    Micronuclei induced by radiation, replication stress, or chromosome segregation errors do not activate cGAS-STING
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    SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production
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    Elevated sleep quota in a stress-resilient Drosophila species
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    Intersectin1 promotes clathrin-mediated endocytosis by organizing and stabilizing endocytic protein interaction networks
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    Cooperation of Various Cytoskeletal Components Orchestrates Intercellular Spread of Mitochondria between B Cells through Tunnelling Nanotubes
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    Human antibody signatures towards the Chlamydia trachomatis major outer membrane protein after natural infection and vaccination
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    Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes
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    Establishing a human-induced pluripotent stem cell line SMUSHi005-A from a patient with hypophosphatemic vitamin D-resistant rickets carrying the PHEX c.1586–1586 + 1delAG mutation
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    Astrogliosis and Neuroinflammation Underlie Scoliosis Upon Cilia Dysfunction
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  45. www.biorxiv.org www.biorxiv.org
    Viral mimicry and memory deficits upon microglial deletion of ATRX
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    Time-dependent effects of tumor necrosis factor α on Ca2+-dependent secretion in murine small intestinal organoids
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    Astrocyte-derived CHI3L1 signaling impairs neurogenesis and cognition in the demyelinated hippocampus
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    The adipose-neural axis is involved in epicardial adipose tissue-related cardiac arrhythmias
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    Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities
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    Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model
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    Repurposing ibudilast to mitigate Alzheimer’s disease by targeting inflammation
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    Microglial CMPK2 promotes neuroinflammation and brain injury after ischemic stroke
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Contrasting consequences of podocyte IGF1R inhibition
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  54. www.sciencedirect.com www.sciencedirect.com
    Transient sensorimotor projections in the developmental song learning period
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    Targeting low levels of MIF expression as a potential therapeutic strategy for ALS
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    Acute response to pathogens in the early human placenta at single-cell resolution
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATG9B regulates bacterial internalization via actin rearrangement
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  58. www.biorxiv.org www.biorxiv.org
    Perturbing nuclear glycosylation in the mouse preimplantation embryo slows down embryonic growth
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    Divergent opioid-mediated suppression of inhibition between hippocampus and neocortex across species and development
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    Beyond Glycolysis: Aldolase A is a Novel Effector in Reelin Mediated Dendritic Development
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  61. www.mdpi.com www.mdpi.com
    IL17A Suppresses IGFBP1 in Human Endometrial Stromal Cells
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    Upregulated GIRK2 counteracts ethanol-induced changes in excitability & respiration in human neurons
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    Mark4 ablation attenuates pathological phenotypes in a mouse model of tauopathy
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  64. www.biorxiv.org www.biorxiv.org
    An opponent striatal circuit for distributional reinforcement learning
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conditional chemoconnectomics (cCCTomics) as a strategy for efficient and conditional targeting of chemical transmission
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    Generation of a lymphoblastoid-derived induced pluripotent stem cell line (CBRCULi015-A) from a patient with congenital myotonic dystrophy
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  67. Apr 2024
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    Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Detection of ER Stress in iPSC-Derived Neurons Carrying the p.N370S Mutation in the GBA1 Gene
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adipocyte-Released Adipomes in Chagas Cardiomyopathy: Impact on Cardiac Metabolic and Immune Regulation
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    Protein degradation of Lysine-specific demethylase 1 is mediated by Bre1 yet opposed by Lsd1-interacting lncRNAs during fly follicle development
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    LKB1 prevents ILC2 exhaustion to enhance antitumor immunity
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    Generation of a KCNQ1 (c.1032 + 2 T > C) mutant human embryonic stem cell line via CRISPR base editing
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    Generation and characterization of six human induced pluripotent stem cell lines (hiPSCs) from three individuals with SSADH Deficiency and CRISPR-corrected isogenic controls
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    The MYCN 5′ UTR as a therapeutic target in neuroblastoma
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    α2δ1-mediated maladaptive sensory plasticity disrupts adipose tissue homeostasis following spinal cord injury
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Growth hormone promotes the reconstruction of injured axons in the hypothalamo-neurohypophyseal system
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    DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice
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    PARP inhibitors suppress tumours via centrosome error-induced senescence independent of DNA damage response
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    Molecular and cellular organization of odorant binding protein genes in Drosophila
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    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells
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    Generation of two induced pluripotent stem cell lines (LVPEIi004-A and LVPEIi005-A) from probands with Leber Congenital Amaurosis 2 (LCA2) and harboring mutations in RPE65
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    ptx3a+ fibroblast/epicardial cells provide a transient macrophage niche to promote heart regeneration
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    Nuclear RNA homeostasis promotes systems-level coordination of cell fate and senescence
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    Cooperation of Various Cytoskeletal Components Orchestrates Intercellular Spread of Mitochondria between B-Lymphoma Cells through Tunnelling Nanotubes
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    Duox activation in Drosophila Malpighian tubules stimulates intestinal epithelial renewal through a countercurrent flow
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    Microglia aging in the hippocampus advances through intermediate states that drive inflammatory activation and cognitive decline
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    Generation of two induced pluripotent stem cell lines (LVPEIi007-B, LVPEIi008-B) from patients harboring homozygous mutation in ABCA4 (c.6088C>T) using non-integrative Sendai virus-based approach
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    Time-series reconstruction of the molecular architecture of human centriole assembly
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    Phosphoinositide detection at synapses of fixed murine hippocampal neurons
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    Functionally diverse thymic medullary epithelial cells interplay to direct central tolerance
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    Bacterial muropeptides promote OXPHOS and suppress mitochondrial stress in mammals
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    Truncating NFKB1 variants cause combined NLRP3 inflammasome activation and type I interferon signaling and predispose to necrotizing fasciitis
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  95. www.nature.com www.nature.com
    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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    Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer
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    The Legionella pneumophila effector DenR hijacks the host NRas proto-oncoprotein to downregulate MAPK signaling
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    Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss
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    Microtubule-associated protein MAP7 promotes tubulin posttranslational modifications and cargo transport to enable osmotic adaptation
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    Endometrial BMP2 Deficiency Impairs ITGB3-Mediated Trophoblast Invasion in Women with Repeated Implantation Failure
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      DOI: 10.1210/endocr/bqae002

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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defects of renal tubular homeostasis and cystogenesis in the Pkhd1-knockout
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  102. Mar 2024
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    Generation of one induced pluripotent stem cell line JUCGRMi004-A from a Charcot-Marie-Tooth disease type 1A (CMT1A) patient with PMP22 duplication
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    Generation of a TSC2 knockout embryonic stem cell line by CRISPR/Cas9 editing
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    Pooled CRISPR screening of high-content cellular phenotypes using ghost cytometry
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    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    Regulation of condensin II by self-suppression and release mechanisms
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  108. www.nature.com www.nature.com
    White and gray matter integrity evaluated by MRI-DTI can serve as noninvasive and reliable indicators of structural and functional alterations in chronic neurotrauma
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    Neuropeptides in the rat claustrum – An immunohistochemical detection
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    Matrilin-3 supports neuroprotection in ischemic stroke by suppressing astrocyte-mediated neuroinflammation
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    Maladaptation of dentate gyrus mossy cells mediates contextual discrimination deficit after traumatic stress
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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cortical brain organoid slices (cBOS) for the study of human neural cells in minimal networks
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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel mechanism of PHB2-mediated mitophagy participating in the development of Parkinson's disease
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    XPA tumor variant leads to defects in NER that sensitize cells to cisplatin
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  116. rupress.org rupress.org
    Medioapical contractile pulses coordinated between cells regulate Drosophila eye morphogenesis
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  117. www.thelancet.com www.thelancet.com
    Female mice display sex-specific differences in cerebrovascular function and subarachnoid haemorrhage-induced injury
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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
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  119. www.sciencedirect.com www.sciencedirect.com
    Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity
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    A gut-derived hormone regulates cholesterol metabolism
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TLR2 regulates hair follicle cycle and regeneration via BMP signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10939499/
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel GABAergic population in the medial vestibular nucleus maintains wakefulness and gates rapid eye movement sleep
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  123. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment
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  124. www.sciencedirect.com www.sciencedirect.com
    Generation of Leber congenital amaurosis, type 12 patient-specific induced pluripotent stem cell line (LVPEIi006-A), harboring a homozygous mutation in RD3
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    Disease-causing Slack potassium channel mutations produce opposite effects on excitability of excitatory and inhibitory neurons
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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C17orf80 binds the mitochondrial genome to promote its replication
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  127. 52.53.155.43 52.53.155.43
    JNEUROSCI.0918-23.2024.full-html.html
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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pip5k1γ regulates axon formation by limiting Rap1 activity
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  129. www.sciencedirect.com www.sciencedirect.com
    Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury
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  130. www.sciencedirect.com www.sciencedirect.com
    OPA1 mediates muscle differentiation by promoting a metabolic switch via the supercomplex assembly factor SCAF1
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    The adhesion G-protein-coupled receptor mayo/CG11318 controls midgut development in Drosophila
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    An iPSC line (FINi003-A) from a male with a late-onset developmental and epileptic encephalopathy caused by a heterozygous gain-of-function p.E1211K variant in the SCN2A gene encoding the voltage-gated sodium channel Nav1.2
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  133. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 targets ribosomal RNA biogenesis
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    Generation and characterization of three CRISPR/Cas9 edited RB1 null hiPSC lines for retinoblastoma disease modelling
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  135. www.biorxiv.org www.biorxiv.org
    Biallelic pathogenic variants in DNAH3 cause male infertility in humans and mice
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  136. www.nature.com www.nature.com
    Genetic labeling of embryonically-born dentate granule neurons in young mice using the PenkCre mouse line
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  137. Feb 2024
  138. www.sciencedirect.com www.sciencedirect.com
    Establishing a human-induced pluripotent stem cell line (SMUSHi003-A) from a patient with Charcot-Marie-Tooth disease and focal segmental glomerulosclerosis
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    Canonical Wnt signaling directs the generation of functional human PSC-derived atrioventricular canal cardiomyocytes in bioprinted cardiac tissues
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  140. link.springer.com link.springer.com
    SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury
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      DOI: 10.1186/s12974-024-03051-5

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    Evolutionary analysis identifies a Golgi pathway and correlates lineage-specific factors with endomembrane organelle emergence in apicomplexans
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    Region-specific cellular and molecular basis of liver regeneration after acute pericentral injury
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  144. jneuroinflammation.biomedcentral.com jneuroinflammation.biomedcentral.com
    Progranulin haploinsufficiency mediates cytoplasmic TDP-43 aggregation with lysosomal abnormalities in human microglia
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    The β6 Integrin Negatively Regulates TLR7-Mediated Epithelial Immunity via Autophagy During Influenza A Virus Infection
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    Generation of a DMD loss-of-function mutant human embryonic stem cell lines by CRISPR base editing
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    Large-scale visualisation of α-synuclein oligomers in Parkinson’s disease brain tissue
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    Spine plasticity of dentate gyrus parvalbumin-positive interneurons is regulated by experience
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma
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    Establishment of an induced pluripotent stem cell line from a Noonan syndrome patient with the heterozygote mutation p.S257L (c.770C>T) in RAF1 gene
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histological and biochemical changes in lymphatic vessels after skeletal muscle injury induced by lengthening contraction in male mice
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  152. www.biorxiv.org www.biorxiv.org
    Flow Cytometry Strategies for Rapidly Characterizing Heterogeneous Adipocyte Populations in 3D In Vitro Constructs
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    Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice
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  154. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Quantitative and qualitative mutational impact of ionizing radiation on normal cells
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  156. www.sciencedirect.com www.sciencedirect.com
    ASICs mediate fast excitatory synaptic transmission for tactile discrimination
    1
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      DOI: 10.1016/j.neuron.2024.01.018

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  157. www.sciencedirect.com www.sciencedirect.com
    BLA DBS improves anxiety and fear by correcting weakened synaptic transmission from BLA to adBNST and CeL in a mouse model of foot shock
    2
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      DOI: 10.1016/j.celrep.2024.113766

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  158. www.sciencedirect.com www.sciencedirect.com
    Generation of two iPSC lines from Mowat-Wilson syndrome patients carrying heterozygous ZEB2 mutations
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  159. www.sciencedirect.com www.sciencedirect.com
    Proline restores mitochondrial function and reverses aging hallmarks in senescent cells
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  160. www.sciencedirect.com www.sciencedirect.com
    Spexin and nesfatin-1-expressing neurons in the male human claustrum
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      DOI: 10.1016/j.jchemneu.2024.102400

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  161. www.sciencedirect.com www.sciencedirect.com
    An enhanced broad-spectrum peptide inhibits Omicron variants in vivo
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      DOI: 10.1016/j.xcrm.2024.101418

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  162. www.sciencedirect.com www.sciencedirect.com
    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
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      DOI: 10.1016/j.celrep.2024.113778

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  163. www.sciencedirect.com www.sciencedirect.com
    ABHD7-mediated depalmitoylation of lamin A promotes myoblast differentiation
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  164. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
    3
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      DOI: 10.1101/2023.12.05.570182

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  165. www.biorxiv.org www.biorxiv.org
    Targeting NGF but not VEGF or BDNF signaling reduces endometriosis-associated pain in mice
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      DOI: 10.1101/2023.12.05.570181

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  166. www.sciencedirect.com www.sciencedirect.com
    Generation of an induced pluripotent stem cell line (LVPEIi002-A) with heterozygous RB1 mutation using peri-orbital fat derived mesenchymal cells of a patient with inherited retinoblastoma
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  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of CD44 suppresses the formation of fibrotic scar after spinal cord injury via the JAK2/STAT3 signaling pathway
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  168. www.sciencedirect.com www.sciencedirect.com
    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
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  169. 52.53.155.43 52.53.155.43
    Adrenal Abcg1 controls cholesterol flux and steroidogenesis
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      DOI: 10.1210/endocr/bqae014

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  170. www.sciencedirect.com www.sciencedirect.com
    An alternative splicing signature defines the basal-like phenotype and predicts worse clinical outcome in pancreatic cancer
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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis
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  172. www.sciencedirect.com www.sciencedirect.com
    Generation of hiPSCs (JUCGRMi003-A) from a patient with Parkinson’s disease with PARK2 mutation
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  173. www.sciencedirect.com www.sciencedirect.com
    PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression
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  174. www.biorxiv.org www.biorxiv.org
    Cell-autonomous targeting of arabinogalactan by host immune factors inhibits mycobacterial growth
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  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
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    Development of sexual dimorphism of skeletal muscles through the adrenal cortex, caused by androgen-induced global gene suppression
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    Chronic social defeat stress induces anxiety-like behaviors via downregulation of serotonin transporter in the prefrontal serotonergic system in mice
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    sciencedirect.com/science/article/pii/S0197018624000093
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    SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
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  179. Jan 2024
  180. www.molbiolcell.org www.molbiolcell.org
    Regulation of condensin II by self-suppression and release mechanisms
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    Selective vulnerability of layer 5a corticostriatal neurons in Huntington’s disease
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  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P. mirabilis-derived pore-forming haemolysin, HpmA drives intestinal alpha-synuclein aggregation in a mouse model of neurodegeneration
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    Generation of a patient-specific iPSC cell line with cardiac arrhythmias and dilated cardiomyopathy (CBRCULi016-A), an isogenic control (CBRCULi016-A-1), and a paternal control (CBRCULi017-A)
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