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Disrupting the interaction between androgen receptor and its coregulator WDR77 delays the growth of treatment-resistant prostate cancer

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1. scibot 11 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116235
  
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sciencedirect.com/science/article/pii/S221112472501006X
Jul 2025
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FMRP-dependent translational control negatively regulates adapter protein complex 2-mediated endocytosis

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1. scibot 24 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113062
  
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sciencedirect.com/science/article/pii/S2589004225013239
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The histone variant H3.14 is an early player in the abiotic stress response of Arabidopsis

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1. scibot 09 Jul 2025
  
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  DOI: 10.1016/j.devcel.2025.06.019
  
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sciencedirect.com/science/article/pii/S1534580725003740
May 2025
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A specific form of cPRC1 containing CBX4 is co-opted to mediate oncogenic gene repression in diffuse midline glioma

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1. scibot 22 May 2025
  
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  DOI: 10.1016/j.molcel.2025.04.026
  
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sciencedirect.com/science/article/pii/S1097276525004058
Feb 2025
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PDF-html.html

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1. scibot 28 Feb 2025
  
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  DOI: 10.1158/0008-5472.can-24-1893
  
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52.53.155.43/687be9d2d25c48928f609b8bb1a6c7ac601f5d4d/PDF-html.html
Jan 2025
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HMOX1-LDHB interaction promotes ferroptosis by inducing mitochondrial dysfunction in foamy macrophages during advanced atherosclerosis

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.devcel.2024.12.011
  
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sciencedirect.com/science/article/pii/S1534580724007330
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

BMP suppresses Wnt signaling via the Bcl11b-regulated NuRD complex to maintain intestinal stem cells

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1. scibot 05 Dec 2024
  
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  DOI: 10.1038/s44318-024-00276-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11612440/
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lncRNAs maintain the functional phase state of nucleolar prion-like protein to facilitate rRNA processing

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.10.036
  
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sciencedirect.com/science/article/pii/S1097276524008761
Nov 2024
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ARF alters PAF1 complex integrity to selectively repress oncogenic transcription programs upon p53 loss

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1. scibot 17 Nov 2024
  
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  DOI: 10.1016/j.molcel.2024.10.020
  
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sciencedirect.com/science/article/pii/S1097276524008608
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Plausible, robust biological oscillations through allelic buffering

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1. scibot 15 Nov 2024
  
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  DOI: 10.1016/j.cels.2024.10.002
  
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sciencedirect.com/science/article/pii/S2405471224002990
Sep 2024
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Lamin chromatin binding is modulated by interactions of different LAP2α domains with lamins and chromatin

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.isci.2024.110869
  
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sciencedirect.com/science/article/pii/S2589004224020947
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Transcriptome-wide quantification of double-stranded RNAs in live mouse tissues by dsRIP-Seq

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1. scibot 24 Sep 2024
  
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  DOI: 10.1016/j.xpro.2021.100366
  
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sciencedirect.com/science/article/pii/S2666166721000733
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TGF-β and RAS jointly unmask primed enhancers to drive metastasis

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.014
  
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sciencedirect.com/science/article/pii/S009286742400905X
Aug 2024
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The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex

1
1. scibot 21 Aug 2024
  
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  DOI: 10.1038/s44318-024-00164-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11329502/
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Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity

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1. scibot 19 Aug 2024
  
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  DOI: 10.1016/j.immuni.2024.07.010
  
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sciencedirect.com/science/article/pii/S1074761324003595
Jul 2024
www.cell.com www.cell.com

m6A modification inhibits miRNAs’ intracellular function, favoring their extracellular export for intercellular communication

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114369
  
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cell.com/cell-reports/abstract/S2211-1247(24)00697-1
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The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex

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1. scibot 12 Jul 2024
  
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  AB_145840
  
  DOI: 10.1038/s44318-024-00164-8
  
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embopress.org/doi/10.1038/s44318-024-00164-8
May 2024
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Opportunistic pathogen Porphyromonas gingivalis targets the LC3B-ceramide complex and mediates lethal mitophagy resistance in oral tumors

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1. scibot 24 May 2024
  
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  DOI: 10.1016/j.isci.2024.109860
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11108982/
Apr 2024
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Defining a TFAP2C-centered transcription factor network during murine peri-implantation

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1. scibot 04 Apr 2024
  
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  DOI: 10.1016/j.devcel.2024.03.015
  
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  DOI: 10.1016/j.devcel.2024.03.015
  
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sciencedirect.com/science/article/pii/S1534580724001850
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The UBE2F-CRL5ASB11-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells

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1. scibot 04 Apr 2024
  
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  DOI: 10.1016/j.devcel.2024.03.018
  
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sciencedirect.com/science/article/pii/S1534580724001837
Mar 2024
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Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes

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1. scibot 22 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113972
  
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  DOI: 10.1016/j.celrep.2024.113972
  
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sciencedirect.com/science/article/pii/S2211124724003000
Feb 2024
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TMED2 promotes glioma tumorigenesis by being involved in EGFR recycling transport

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1. scibot 14 Feb 2024
  
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  DOI: 10.1016/j.ijbiomac.2024.130055
  
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sciencedirect.com/science/article/pii/S0141813024008584
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Acetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling

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1. scibot 08 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.108943
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10850750/
Jan 2024
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ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.devcel.2023.12.018
  
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sciencedirect.com/science/article/pii/S1534580723006986
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Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres

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1. scibot 14 Jan 2024
  
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  DOI: 10.1016/j.isci.2023.108655
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10783591/
Dec 2023
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SON is an essential m6A target for hematopoietic stem cell fate

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1. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.stem.2023.11.006
  
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sciencedirect.com/science/article/pii/S1934590923003983
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

K+/Cl− cotransporter 2 (KCC2) and Na+/[... formula ...] cotransporter 1 (NBCe1) interaction modulates profile of KCC2 phosphorylation

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1. scibot 27 Oct 2023
  
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  DOI: 10.3389/fncel.2023.1253424
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10595033/
Sep 2023
link.springer.com link.springer.com

SMYD2 regulates vascular smooth muscle cell phenotypic switching and intimal hyperplasia via interaction with myocardin

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1. scibot 07 Sep 2023
  
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  DOI: 10.1007/s00018-023-04883-9
  
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link.springer.com/article/10.1007/s00018-023-04883-9
Aug 2023
52.53.155.43 52.53.155.43

PIIS221112472300952X-html.html

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112941
  
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52.53.155.43/1abfd5fba02bda950654c5dfd88ce712e0bc4f04/PIIS221112472300952X-html.html
52.53.155.43 52.53.155.43

Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis

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1. scibot 17 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112944
  
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2. scibot 11 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112944
  
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52.53.155.43/f1aa479ee50c1426738d478d555cd8c52a91c49e/PIIS2211124723009555-html.html
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation

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1. scibot 29 Jun 2023
  
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  DOI: 10.1016/j.neuron.2023.05.033
  
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sciencedirect.com/science/article/pii/S0896627323004348
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QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism

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1. scibot 28 Jun 2023
  
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  DOI: 10.1016/j.cell.2023.05.047
  
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sciencedirect.com/science/article/pii/S0092867423005986
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

(A) Elevated expression of histone deacetylase HDAC8 suppresses arginine-proline metabolism in necrotizing enterocolitis

1
1. scibot 01 Jun 2023
  
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  DOI: 10.1016/j.isci.2023.106882
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10227426/
May 2023
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SMYD2 Regulates Vascular Smooth Muscle Cell Phenotypic Switching and Intimal Hyperplasia via Interaction with Myocardin

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PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1

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USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities

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Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma

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CHD1 promotes sensitivity to Aurora kinase inhibitors by suppressing interaction of AURKA with its coactivator TPX2

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Role of FGF10/FGFR2b Signaling in Homeostasis and Regeneration of Adult Lacrimal Gland and Corneal Epithelium Proliferation

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METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

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Hypoxic activation of PFKFB4 in breast tumor microenvironment shapes metabolic and cellular plasticity to accentuate metastatic competence

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Protocol to use RNaseH1-based CRISPR to modulate locus-associated R-loops

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can-22-0631-html.html

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The BASP1 transcriptional corepressor modifies chromatin through lipid-dependent and lipid-independent mechanisms

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The redox cycling of STAT2 maintains innate immune homeostasis

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YAP1 maintains active chromatin state in head and neck squamous cell carcinomas that promotes tumorigenesis through cooperation with BRD4

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A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency

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Chromatin remodeling is restricted by transient GATA6 binding during iPSC differentiation to definitive endoderm

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A plasma membrane-localized polycystin-1/polycystin-2 complex in endothelial cells elicits vasodilation

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Feb 2022
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Histone chaperone FACT complex coordinates with HIF to mediate an expeditious transcription program to adapt to poorly oxygenated cancers

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Vitamin D receptor, STAT3, and TET2 cooperate to establish tolerogenesis

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Synaptotagmin-11 inhibits spontaneous neurotransmission through vti1a

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Identifying and characterising Thrap3, Bclaf1 and Erh interactions using cross-linking mass spectrometry

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NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer

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Manipulation of TAD reorganization by chemical-dependent genome linking

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A Translational Repression Complex in Developing Mammalian Neural Stem Cells that Regulates Neuronal Specification

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Untitled document

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Untitled document

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Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling

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Suv4-20h2 protects against influenza virus infection by suppression of chromatin loop formation

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May 2021
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Phase separation of OCT4 controls TAD reorganization to promote cell fate transitions

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GATA6 defines endoderm fate by controlling chromatin accessibility during differentiation of human-induced pluripotent stem cells

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Parental genome unification is highly error-prone in mammalian embryos

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Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency

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Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output

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Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

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Transcriptome-wide quantification of double-stranded RNAs in live mouse tissues by dsRIP-Seq

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Sirtuin-1 Inhibits Endothelin-2 Expression in Human Granulosa-Lutein Cells via HIF1A and Epigenetic Modifications †

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academic.oup.com/biolreprod/article/104/2/387/5941972
Feb 2021
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R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis

1
1. scibot 28 Feb 2021
  
  in Public
  
  RRID:AB_145840
  
  DOI: 10.1016/j.molcel.2020.12.026
  
  Resource: (Millipore Cat# 12-371, RRID:AB_145840)
  
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sciencedirect.com/science/article/pii/S1097276520309473
Sep 2020
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Acetylation of UHRF1 Regulates Hemi-methylated DNA Binding and Maintenance of Genome-wide DNA Methylation

1
1. scibot 23 Sep 2020
  
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  RRID:AB_145840
  
  DOI: 10.1016/j.celrep.2020.107958
  
  Resource: (Millipore Cat# 12-371, RRID:AB_145840)
  
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sciencedirect.com/science/article/pii/S2211124720309396
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FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism

1
1. scibot 23 Sep 2020
  
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  RRID:AB_145840
  
  DOI: 10.1016/j.celrep.2020.02.076
  
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sciencedirect.com/science/article/pii/S2211124720302503
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Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer

1
1. scibot 17 Sep 2020
  
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  RRID:AB_145840
  
  DOI: 10.1016/j.ccell.2020.01.011
  
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sciencedirect.com/science/article/pii/S1535610820300507
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Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells

1
1. scibot 16 Sep 2020
  
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  RRID:AB_145840
  
  DOI: 10.1016/j.celrep.2020.107715
  
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sciencedirect.com/science/article/pii/S2211124720306926
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ADAR1-Dependent RNA Editing Promotes MET and iPSC Reprogramming by Alleviating ER Stress

1
1. scibot 07 Sep 2020
  
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  RRID:AB_145840
  
  DOI: 10.1016/j.stem.2020.04.016
  
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sciencedirect.com/science/article/pii/S1934590920301557
Jan 2020
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PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation

1
1. scibot 13 Jan 2020
  
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  RRID:AB_145840
  
  DOI: 10.1016/j.molcel.2019.08.012
  
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sciencedirect.com/science/article/pii/S1097276519306288
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Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:AB_145840
  
  DOI: 10.1016/j.celrep.2019.04.008
  
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sciencedirect.com/science/article/pii/S2211124719304632
Nov 2018
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A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities

1
1. scibot 05 Nov 2018
  
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  12371
  
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sciencedirect.com/science/article/pii/S1097276518301862
elifesciences.org elifesciences.org

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation

1
1. scibot 05 Nov 2018
  
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  RRID:AB_145840
  
  Curator: @evieth
  
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elifesciences.org/articles/31879
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Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element

1
1. scibot 05 Nov 2018
  
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  RRID:AB_145840
  
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sciencedirect.com/science/article/pii/S0092867418304008
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Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions

1
1. scibot 05 Nov 2018
  
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  RRID:AB_145840
  
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sciencedirect.com/science/article/pii/S1097276517308808
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Method for the Acute and Rapid Degradation of Endogenous Proteins

2
1. scibot 05 Nov 2018
  
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  RRID:AB_145840
  
  Curator: @evieth
  
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2. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_145840
  
  Curator: @evieth
  
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  (Millipore Cat# 12-371, RRID:AB_145840)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5733393/
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Nuclear TRIM25 Specifically Targets Influenza Virus Ribonucleoproteins to Block the Onset of RNA Chain Elongation

1
1. scibot 05 Nov 2018
  
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  RRID:AB_145840
  
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sciencedirect.com/science/article/pii/S1931312817304389
europepmc.org europepmc.org

The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline.

1
1. scibot 05 Nov 2018
  
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  AB_145840
  
  Curator: @evieth
  
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  (Millipore Cat# 12-371, RRID:AB_145840)
  
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europepmc.org/articles/PMC5703642/
Nov 2017
elifesciences.org elifesciences.org

KChIP2 is a core transcriptional regulator of cardiac excitability

1
1. scibot 08 Nov 2017
  
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  AB_145840
  
  Curator: @gabimpine
  
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elifesciences.org/content/6/e17304

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