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34 Matching Annotations

Apr 2026
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Graded activation of the CLEAR network through mTORC1 suppression on cargo-harboring lysosomes

1
1. scibot 11 Apr 2026
  
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  RRID:AB_1523267
  
  DOI: 10.1016/j.celrep.2026.117228
  
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sciencedirect.com/science/article/pii/S2211124726003062
Jan 2026
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Cathepsin-D-mediated MHC class I degradation contributes to immune evasion in colorectal cancer

1
1. scibot 06 Jan 2026
  
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  DOI: 10.1016/j.xcrm.2025.102534
  
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sciencedirect.com/science/article/pii/S266637912500607X
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Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry

1
1. scibot 06 Jan 2026
  
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  DOI: 10.1016/j.neuron.2025.11.009
  
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sciencedirect.com/science/article/pii/S0896627325008566
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The proteostatic landscape of healthy human oocytes

1
1. scibot 21 Aug 2025
  
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  RRID:AB_1523267
  
  DOI: 10.1038/s44318-025-00493-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12361380/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Pathological axonal enlargement in connection with amyloidosis, lysosome destabilization, and bleeding is a major defect in Alzheimer’s disease

1
1. scibot 04 Jul 2025
  
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  RRID:AB_1523267
  
  DOI: 10.4103/NRR.NRR-D-24-01440
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12220713/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Molecular elucidation of brain lipofuscin in aging and Neuronal Ceroid Lipofuscinosis

1
1. scibot 19 Apr 2025
  
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  RRID:AB_1523267
  
  DOI: 10.21203/rs.3.rs-6010379/v1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11957193/
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STING mediates lysosomal quality control and recovery through its proton channel function and TFEB activation in lysosomal storage disorders

1
1. scibot 05 Apr 2025
  
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  RRID:AB_1523267
  
  DOI: 10.1016/j.molcel.2025.03.008
  
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sciencedirect.com/science/article/pii/S1097276525002011
Mar 2025
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KCTD20 suppression mitigates excitotoxicity in tauopathy patient organoids

1
1. scibot 06 Mar 2025
  
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  RRID:AB_1523267
  
  DOI: 10.1016/j.neuron.2025.02.001
  
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sciencedirect.com/science/article/pii/S089662732500114X
Oct 2024
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Type I IFN drives unconventional IL-1β secretion in lupus monocytes

1
1. scibot 09 Oct 2024
  
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  DOI: 10.1016/j.immuni.2024.09.004
  
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sciencedirect.com/science/article/pii/S1074761324004485
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Arf1-dependent LRBA recruitment to Rab4 endosomes is required for endolysosome homeostasis

1
1. scibot 05 Oct 2024
  
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  RRID:AB_1523267
  
  DOI: 10.1083/jcb.202401167
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11449124/
Sep 2024
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Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis

1
1. scibot 11 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114728
  
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sciencedirect.com/science/article/pii/S2211124724010799
May 2024
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

AdipoRon promotes amyloid-β clearance through enhancing autophagy via nuclear GAPDH-induced sirtuin 1 activation in Alzheimer's disease

1
1. scibot 03 May 2024
  
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  RRID:AB_1523267
  
  DOI: 10.1111/bph.16400
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16400
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A multiomics analysis-assisted deep learning model identifies a macrophage-oriented module as a potential therapeutic target in colorectal cancer

1
1. scibot 02 Mar 2024
  
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  RRID:AB_1523267
  
  DOI: 10.1016/j.xcrm.2024.101399
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10897549/
Oct 2023
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Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance

1
1. scibot 17 Oct 2023
  
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  AB_1523267
  
  DOI: 10.1126/sciadv.abo3610
  
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science.org/doi/10.1126/sciadv.abo3610
Aug 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance

2
1. scibot 13 Aug 2022
  
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  AB_1523267
  
  DOI: 10.1126/sciadv.abo3610
  
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2. scibot 13 Aug 2022
  
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  AB_1523267
  
  DOI: 10.1126/sciadv.abo3610
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9299535/
Jul 2022
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Impaired interferon-γ signaling promotes the development of silicosis

1
1. scibot 08 Jul 2022
  
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  RRID:AB_1523267
  
  DOI: 10.1016/j.isci.2022.104647
  
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sciencedirect.com/science/article/pii/S2589004222009191
Jun 2022
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Parkinson’s disease-risk protein TMEM175 is a proton-activated proton channel in lysosomes

1
1. scibot 24 Jun 2022
  
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  RRID:AB_1523267
  
  DOI: 10.1016/j.cell.2022.05.021
  
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sciencedirect.com/science/article/pii/S0092867422006523
rupress.org rupress.org

ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling

1
1. scibot 09 Jun 2022
  
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  RRID:AB_1523267
  
  DOI: 10.1083/jcb.202106046
  
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rupress.org/jcb/article/221/7/e202106046/213259/ER-lysosome-lipid-transfer-protein-VPS13C-PARK23
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Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis

1
1. scibot 02 Jun 2022
  
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  RRID:AB_1523267
  
  DOI: 10.1016/j.celrep.2022.110851
  
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sciencedirect.com/science/article/pii/S2211124722006246
Apr 2022
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KIBRA regulates amyloid β metabolism by controlling extracellular vesicles secretion

1
1. scibot 07 Apr 2022
  
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  RRID:AB_1523267
  
  DOI: 10.1016/j.ebiom.2022.103980
  
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sciencedirect.com/science/article/pii/S2352396422001645
Feb 2022
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E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression

1
1. scibot 04 Feb 2022
  
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  RRID:AB_1523267
  
  DOI: 10.1016/j.molcel.2022.01.002
  
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sciencedirect.com/science/article/pii/S1097276522000028
Dec 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells

1
1. scibot 02 Dec 2021
  
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  RRID:AB_1523267
  
  DOI: 10.1158/0008-5472.CAN-20-3371
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8178204/
Nov 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Basal forebrain magnocellular cholinergic systems are damaged in mice following neonatal hypoxia-ischemia

1
1. scibot 17 Nov 2021
  
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  AB_75852
  
  DOI: 10.1002/cne.25263
  
  Resource: (Abcam Cat# ab75852, RRID:AB_1523267)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_1523267
  
  Curator comments: Cathepsin D antibody [EPR3057Y] Abcam Cat# ab75852
  
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  RRIDCUR:NotRRID RRIDCUR:Unresolved RRID:AB_1523267
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onlinelibrary.wiley.com/doi/10.1002/cne.25263
Aug 2021
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Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

1
1. scibot 27 Aug 2021
  
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  RRID:AB_1523267
  
  DOI: 10.1016/j.cell.2021.08.002
  
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sciencedirect.com/science/article/pii/S0092867421009442
Jul 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Valproic acid affects neuronal fate and microglial function via enhancing autophagic flux in mice after traumatic brain injury

1
1. scibot 29 Jul 2021
  
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  RRID: AB_1523267
  
  DOI: 10.1111/jnc.14892
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.14892
Apr 2021
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Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome

1
1. scibot 23 Apr 2021
  
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  RRID:AB_1523267
  
  DOI: 10.1016/j.cell.2021.03.048
  
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  RRID:AB_1523267 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867421003792
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PIKfyve activity is required for lysosomal trafficking of tau aggregates and tau seeding

1
1. scibot 07 Apr 2021
  
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  AB_1523267
  
  DOI: 10.1016/j.jbc.2021.100636
  
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sciencedirect.com/science/article/pii/S0021925821004221
Sep 2020
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Quantitative and Dynamic Catalogs of Proteins Released during Apoptotic and Necroptotic Cell Death

1
1. scibot 17 Sep 2020
  
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  RRID:AB_1523267
  
  DOI: 10.1016/j.celrep.2019.12.079
  
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  RRIDCUR:Validated RRID:AB_1523267
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sciencedirect.com/science/article/pii/S2211124719317449
insight.jci.org insight.jci.org

The UPR preserves mature oligodendrocyte viability and function in adults by regulating autophagy of PLP

1
1. scibot 04 Sep 2020
  
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  cathepsin D
  
  DOI: 10.1172/jci.insight.132364
  
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  Curator: @Naa003
  
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  Curator comments: Cathepsin D antibody [EPR3057Y] Abcam Cat# ab75852
  
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  RRID:AB_1523267 RRIDCUR:Missing
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insight.jci.org/articles/view/132364
Jan 2020
iovs.arvojournals.org iovs.arvojournals.org

Retinal Pigment Epithelium Cell Death Is Associated With NLRP3 Inflammasome Activation by All-trans Retinal

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1523267
  
  DOI: 10.1167/iovs.18-26360
  
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  RRID:AB_1523267 RRIDCUR:Validated
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iovs.arvojournals.org/article.aspx
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NOX1-Dependent mTORC1 Activation via S100A9 Oxidation in Cancer Stem-like Cells Leads to Colon Cancer Progression

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1523267
  
  DOI: 10.1016/j.celrep.2019.06.085
  
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  RRID:AB_1523267 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719308654
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Presynaptic Endosomal Cathepsin D Regulates the Biogenesis of GABAergic Synaptic Vesicles

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1523267
  
  DOI: 10.1016/j.celrep.2019.06.006
  
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  RRID:AB_1523267 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719307648
onlinelibrary.wiley.com onlinelibrary.wiley.com

Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1523267
  
  DOI: 10.1111/jnc.14312
  
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onlinelibrary.wiley.com/doi/full/10.1111/jnc.14312