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Glycogen synthase kinase-3 is essential for Treg development and function

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Aug 2025
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1-s2.0-S2589004225015111-main-html.html

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Jul 2025
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Antibody-mediated TGF-β1 activation for the treatment of diseases caused by deleterious T cell activity

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1. scibot 30 Jul 2025
  
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APOE protects against severe infection with Mycobacterium tuberculosis by restraining production of neutrophil extracellular traps

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  DOI: 10.1371/journal.ppat.1013267
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12201663/
Jun 2025
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Targeting the CD40 costimulatory receptor to improve virotherapy efficacy in diffuse midline gliomas

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A percolation phase transition controls complement protein coating of surfaces

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Protocol to isolate and quantify large aging neutrophil-derived vesicles

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  DOI: 10.1016/j.xpro.2025.103886
  
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RORγt is crucial for gut homeostasis by regulating the expression of HB-EGF rather than IL-22 in activated ILC3s

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cell.com/cell-reports/abstract/S2211-1247(25)00564-9
May 2025
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Microbiota-derived urocanic acid triggered bytyrosine kinase inhibitors potentiates cancer immunotherapy efficacy

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  DOI: 10.1016/j.chom.2025.04.022
  
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MCRS1 sensitizes T cell–dependent immunotherapy by augmenting MHC-I expression in solid tumors

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1. scibot 19 May 2025
  
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  DOI: 10.1084/jem.20240959
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11572484/
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Microglia and CD8+ T cell activation precede neuronal loss in a murine model of spastic paraplegia 15

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1. scibot 19 May 2025
  
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  DOI: 10.1084/jem.20232357
  
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Activation of the endoplasmic reticulum stress regulator IRE1α compromises pulmonary host defenses

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  DOI: 10.1016/j.celrep.2025.115632
  
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sciencedirect.com/science/article/pii/S2211124725004036
Apr 2025
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Protocol for renal subcapsular islet transplantation in diabetic mice to induce long-term immune tolerance

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1. scibot 08 Apr 2025
  
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  DOI: 10.1016/j.xpro.2025.103729
  
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sciencedirect.com/science/article/pii/S2666166725001352
Mar 2025
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Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.devcel.2025.02.016
  
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sciencedirect.com/science/article/pii/S1534580725001212
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Translation dysregulation in cancer as a source for targetable antigens

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  DOI: 10.1016/j.ccell.2025.03.003
  
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sciencedirect.com/science/article/pii/S1535610825000820
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23ME-01473, an Fc Effector–Enhanced Anti-ULBP6/2/5 Antibody, Restores NK Cell–Mediated Antitumor Immunity through NKG2D and FcγRIIIa Activation

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1. scibot 27 Mar 2025
  
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  DOI: 10.1158/2767-9764.CRC-24-0478
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11927390/
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Plasma membrane folding enables constant surface area-to-volume ratio in growing mammalian cells

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.cub.2025.02.051
  
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sciencedirect.com/science/article/pii/S0960982225002659
Feb 2025
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Sweetener aspartame aggravates atherosclerosis through insulin-triggered inflammation

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.cmet.2025.01.006
  
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Distinct cellular mechanisms underlie chemotherapies and PD-L1 blockade combinations in triple-negative breast cancer

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  DOI: 10.1016/j.ccell.2025.01.007
  
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Jan 2025
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Phenotypic plasticity and increased infiltration of peripheral blood-derived TREM1+ mono-macrophages following radiotherapy in rectal cancer

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  DOI: 10.1016/j.xcrm.2024.101887
  
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Splenic fibroblasts control marginal zone B cell movement and function via two distinct Notch2-dependent regulatory programs

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  DOI: 10.1016/j.immuni.2024.12.003
  
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Dec 2024
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Comprehensive method for producing high-affinity mouse monoclonal antibodies of various isotypes against (4-hydroxy-3-nitrophenyl)acetyl (NP) hapten

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  DOI: 10.1016/j.heliyon.2024.e40837
  
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sciencedirect.com/science/article/pii/S2405844024168685
Nov 2024
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In vivo models of subclonal oncogenesis and dependency in hematopoietic malignancy

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  DOI: 10.1016/j.ccell.2024.10.009
  
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Sep 2024
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Protocol for assessing murine cell doublet engagement and subsequent effects using flow cytometry and imaging flow cytometry

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  DOI: 10.1016/j.xpro.2024.103152
  
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Distinct tumor architectures and microenvironments for the initiation of breast cancer metastasis in the brain

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Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity

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Aug 2024
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Refined tamoxifen administration in mice by encouraging voluntary consumption of palatable formulations

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  DOI: 10.1038/s41684-024-01409-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11291282/
Jul 2024
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de057abe614262e4e5c59c6683970ba76047-html.html

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  DOI: 10.3389/fmolb.2024.1366259
  
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52.53.155.43/867c9ce570a9187427403edd3cbefccb3f730622/de057abe614262e4e5c59c6683970ba76047-html.html
May 2024
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Decreased GATA3 levels cause changed mouse cutaneous innate lymphoid cell fate, facilitating hair follicle recycling

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  DOI: 10.1016/j.devcel.2024.04.015
  
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Apr 2024
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AXL/WRNIP1 mediates replication stress response and promotes therapy resistance and metachronous metastasis in HER2+ breast cancer

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  DOI: 10.1158/0008-5472.CAN-23-1459
  
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aacrjournals.org/cancerres/article/84/5/675/734930/AXL-WRNIP1-Mediates-Replication-Stress-Response
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Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection

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  DOI: 10.1016/j.immuni.2024.03.016
  
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sciencedirect.com/science/article/pii/S1074761324001377
Mar 2024
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Type-I-interferon-responsive microglia shape cortical development and behavior

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  DOI: 10.1016/j.cell.2024.02.020
  
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  DOI: 10.1016/j.cell.2024.02.020
  
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VISTA promotes the metabolism and differentiation of myeloid-derived suppressor cells by STAT3 and polyamine-dependent mechanisms

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  DOI: 10.1016/j.celrep.2023.113661
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10851928/
Feb 2024
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The XCL1-Mediated DNA Vaccine Targeting Type 1 Conventional Dendritic Cells Combined with Gemcitabine and Anti-PD1 Antibody Induces Potent Antitumor Immunity in a Mouse Lung Cancer Model

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1. scibot 15 Feb 2024
  
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  DOI: 10.3390/ijms25031880
  
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mdpi.com/1422-0067/25/3/1880
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Palmitoylation alters LDHA activity and pancreatic cancer response to chemotherapy

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  DOI: 10.1016/j.canlet.2024.216696
  
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Glioblastoma Extracellular Vesicles Modulate Immune PD-L1 Expression in Accessory Macrophages upon Radiotherapy

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Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk

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Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma

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qiad158-html.html

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Protocol for examining the capability of senescent tumor cells to stimulate murine bone-marrow-derived dendritic cells by flow cytometry

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Stress-induced β cell early senescence confers protection against type 1 diabetes

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Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing

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Enhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors

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Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis

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Refined Tamoxifen Administration in Mice by Encouraging Voluntary Consumption of Palatable Formulations

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Protocol for analyzing transforming growth factor β signaling in dextran-sulfate-sodium-induced colitic mice using flow cytometry and western blotting

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FGF21/FGFR1-β-KL cascade in cardiomyocytes modulates angiogenesis and inflammation under metabolic stress

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A neutrophil response linked to tumor control in immunotherapy

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SETDB1 Restrains Endogenous Retrovirus Expression and Antitumor Immunity during Radiotherapy

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Curative islet and hematopoietic cell transplantation in diabetic mice without toxic bone marrow conditioning

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Intratumoral Treatment with 5-Androstene-3β, 17α-Diol Reduces Tumor Size and Lung Metastasis in a Triple-Negative Experimental Model of Breast Cancer

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Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy

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Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation

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The ketone body β-hydroxybutyrate mitigates ILC2-driven airway inflammation by regulating mast cell function

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Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease

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Yin and Yang of Cannabinoid CB1 receptor: CB1 Deletion in Immune Cells Causes Exacerbation While CB1 Deletion in Non-immune Cells Attenuates Obesity

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Integrated single-cell transcriptomic analyses reveal that GPNMB-high macrophages promote PN-MES transition and impede T cell activation in GBM

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NR2F1 is a barrier to dissemination of early stage breast cancer cells.

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Single-cell atlas of the aging mouse colon

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Thymidine starvation promotes c-di-AMP-dependent inflammation during pathogenic bacterial infection

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Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction

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Pathogen size alters C-type lectin receptor signaling in dendritic cells to influence CD4 Th9 cell differentiation

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Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy

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mMCP7, a Mouse Ortholog of δ Tryptase, Mediates Pelvic Tactile Allodynia in a Model of Chronic Pelvic Pain

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Mass cytometry profiling of human dendritic cells in blood and tissues

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Oct 2021
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IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation

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Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope

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Targeted Delivery of Antigen to Activated CD169+ Macrophages Induces Bias for Expansion of CD8+ T Cells

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Untitled document

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  DOI: 10.1016/j.immuni.2018.09.024
  
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IgE Effector Mechanisms, in Concert with Mast Cells, Contribute to Acquired Host Defense against Staphylococcus aureus

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1. scibot 06 May 2021
  
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  RRID:AB_1574973
  
  DOI: 10.1016/j.immuni.2020.08.002
  
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Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA

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1. scibot 06 May 2021
  
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  RRID:AB_1574973
  
  DOI: 10.1016/j.immuni.2020.04.015
  
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Core liver homeostatic co-expression networks are preserved but respond to perturbations in an organism- and disease-specific manner

1
1. scibot 06 May 2021
  
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  RRID:AB_1574973
  
  DOI: 10.1016/j.cels.2021.04.004
  
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sciencedirect.com/science/article/pii/S2405471221001137
Apr 2021
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Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections

1
1. scibot 29 Apr 2021
  
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  RRID:AB_1574973
  
  DOI: 10.1016/j.immuni.2021.04.002
  
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Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity

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  DOI: 10.1016/j.cell.2020.11.009
  
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cell.com/cell/fulltext/S0092-8674(20)31526-9
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The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis

1
1. scibot 24 Apr 2021
  
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  DOI: 10.1016/j.cell.2020.06.029
  
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Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity

1
1. scibot 23 Apr 2021
  
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  RRID:AB_1574973
  
  DOI: 10.1016/j.cell.2020.05.050
  
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The CD94/NKG2A inhibitory receptor educates uterine NK cells to optimize pregnancy outcomes in humans and mice

1
1. scibot 22 Apr 2021
  
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  RRID:AB_1574973
  
  DOI: 10.1016/j.immuni.2021.03.021
  
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sciencedirect.com/science/article/pii/S1074761321001333
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inducible mechanisms of disease tolerance provide an alternative strategy of acquired immunity to malaria

1
1. scibot 28 Mar 2021
  
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  RRID:AB_1574973
  
  DOI: 10.7554/eLife.63838
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7987336/
Feb 2021
journals.plos.org journals.plos.org

Prolyl hydroxylase domain 2 reduction enhances skeletal muscle tissue regeneration after soft tissue trauma in mice

1
1. scibot 25 Feb 2021
  
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  DOI: 10.1371/journal.pone.0233261
  
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journals.plos.org/plosone/article
Dec 2020
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CD103+ cDC1 and endogenous CD8+ T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function

1
1. scibot 09 Dec 2020
  
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  RRID:AB_1574973
  
  DOI: 10.1038/s41467-020-19833-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7710757/
Oct 2020
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Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury

1
1. scibot 10 Oct 2020
  
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  RRID:AB_1574973
  
  DOI: 10.7554/eLife.60165
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7538157/
Sep 2020
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Protocol for Efficient CRISPR/Cas9/AAV-Mediated Homologous Recombination in Mouse Hematopoietic Stem and Progenitor Cells

1
1. scibot 26 Sep 2020
  
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  RRID:AB_1574973
  
  DOI: 10.1016/j.xpro.2020.100028
  
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GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes

1
1. scibot 26 Sep 2020
  
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  RRID:AB_1574973
  
  DOI: 10.1038/s41598-020-69913-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7400764/
www.frontiersin.org www.frontiersin.org

Potential Novel Risk Factor for Breast Cancer: Toxocara canis Infection Increases Tumor Size Due to Modulation of the Tumor Immune Microenvironment

1
1. scibot 16 Sep 2020
  
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  RRID:AB_1574973
  
  DOI: 10.3389/fonc.2020.00736
  
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frontiersin.org/article/10.3389/fonc.2020.00736/full
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Astrocyte- and Neuron-Derived CXCL1 Drives Neutrophil Transmigration and Blood-Brain Barrier Permeability in Viral Encephalitis

1
1. scibot 16 Sep 2020
  
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  AB_1574973
  
  DOI: 10.1016/j.celrep.2020.108150
  
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pubmed.ncbi.nlm.nih.gov/32937134/
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Non-canonical Caspase-1 Signaling Drives RIP2-Dependent and TNF-α-Mediated Inflammation In Vivo

1
1. scibot 15 Sep 2020
  
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  RRID:AB_1574973
  
  DOI: 10.1016/j.celrep.2020.01.090
  
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sciencedirect.com/science/article/pii/S2211124720301248
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Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes

1
1. scibot 05 Sep 2020
  
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  RRID:AB_1574973
  
  DOI: 10.1016/j.cmet.2020.03.002
  
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sciencedirect.com/science/article/pii/S1550413120301170
Aug 2020
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Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction

1
1. scibot 17 Aug 2020
  
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  RRID:AB_157497
  
  DOI: 10.1016/j.neuron.2020.03.031
  
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sciencedirect.com/science/article/pii/S0896627320302385
Jan 2020
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Salmonella Effector SteE Converts the Mammalian Serine/Threonine Kinase GSK3 into a Tyrosine Kinase to Direct Macrophage Polarization

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1574973
  
  DOI: 10.1016/j.chom.2019.11.002
  
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sciencedirect.com/science/article/pii/S1931312819305840
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Expansion of Luminal Progenitor Cells in the Aging Mouse and Human Prostate

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1574973
  
  DOI: 10.1016/j.celrep.2019.07.007
  
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sciencedirect.com/science/article/pii/S2211124719308976
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Untitled document

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  RRID:AB_1574973
  
  DOI: 10.1016/j.ccell.2019.02.006
  
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sciencedirect.com/science/article/pii/S1535610819301011
Nov 2018
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Peroxisome Proliferator-Activated Receptor γ Is Essential for the Resolution of Staphylococcus aureus Skin Infections

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1931312818303706
Nov 2017
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IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis

1
1. scibot 08 Nov 2017
  
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  AB_1574973
  
  Curator: @chewbeccax
  
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sciencedirect.com/science/article/pii/S155041311730342X
www.jneurosci.org www.jneurosci.org

Macrophage Transcriptional Profile Identifies Lipid Catabolic Pathways That Can Be Therapeutically Targeted after Spinal Cord Injury

2
1. scibot 08 Nov 2017
  
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  AB_1574973
  
  Curator: @chewbeccax
  
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2. scibot 08 Nov 2017
  
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  AB_1574973
  
  Curator: @patriciaelyse_
  
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jneurosci.org/content/37/9/2362
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Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo

1
1. scibot 08 Nov 2017
  
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  AB_1574973
  
  Curator: @Zeljana_Babic
  
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sciencedirect.com/science/article/pii/S1535610817300995

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