53 Matching Annotations
  1. Apr 2024
  2. link.springer.com link.springer.com
    Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation
    1
    1. scibot 24 Apr 2024
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      DOI: 10.1038/s41594-024-01294-7

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    link.springer.com/article/10.1038/s41594-024-01294-7
  3. Mar 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    XPA tumor variant leads to defects in NER that sensitize cells to cisplatin
    1
    1. scibot 22 Mar 2024
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      DOI: 10.1093/narcan/zcae013

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    ncbi.nlm.nih.gov/pmc/articles/PMC10946055/
  5. Feb 2024
  6. www.biorxiv.org www.biorxiv.org
    Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation
    1
    1. scibot 15 Feb 2024
      RRID:AB_1587578

      DOI: 10.1101/2023.12.20.572718

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    biorxiv.org/content/10.1101/2023.12.20.572718v1
  7. www.sciencedirect.com www.sciencedirect.com
    Prenatal hormone stress triggers embryonic cardiac hypertrophy outcome by ubiquitin-dependent degradation of mitochondrial mitofusin 2
    1
    1. scibot 09 Feb 2024
      RRID:AB_1587578

      DOI: 10.1016/j.isci.2023.108690

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    sciencedirect.com/science/article/pii/S2589004223027670
  8. Dec 2023
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquiton—An inducible, linkage-specific polyubiquitylation tool
    1
    1. scibot 16 Dec 2023
      RRID:AB_1587578

      DOI: 10.1016/j.molcel.2023.11.016

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    ncbi.nlm.nih.gov/pmc/articles/PMC10804999/
  10. Nov 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Autophagy-mediated control of ribosome homeostasis in oncogene-induced senescence
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113381

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    sciencedirect.com/science/article/pii/S2211124723013931
  12. Aug 2023
  13. www.sciencedirect.com www.sciencedirect.com
    Senescent cells form nuclear foci that contain the 26S proteasome
    1
    1. scibot 04 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112880

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    sciencedirect.com/science/article/pii/S2211124723008914
  14. Apr 2023
  15. www.sciencedirect.com www.sciencedirect.com
    DTX3L E3 ligase targets p53 for degradation at poly ADP-ribose polymerase-associated DNA damage sites
    1
    1. scibot 13 Apr 2023
      RRID:AB_1587578

      DOI: 10.1016/j.isci.2023.106444

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    sciencedirect.com/science/article/pii/S2589004223005217
  16. Feb 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Loss of C9orf72 perturbs the Ran-GTPase gradient and nucleocytoplasmic transport, generating compositionally diverse Importin β-1 granules
    1
    1. scibot 24 Feb 2023
      RRID:AB_1587578

      DOI: 10.1016/j.celrep.2023.112134

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    sciencedirect.com/science/article/pii/S2211124723001456
  18. www.nature.com www.nature.com
    The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
    1
    1. scibot 04 Feb 2023
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      DOI: 10.1038/s41467-023-36058-2

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    nature.com/articles/s41467-023-36058-2
  19. Dec 2022
  20. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Characterization of huntingtin interactomes and their dynamic responses in living cells by proximity proteomics
    1
    1. scibot 05 Dec 2022
      RRID:AB_1587578

      DOI: 10.1111/jnc.15726

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.15726
  21. Sep 2022
  22. www.sciencedirect.com www.sciencedirect.com
    Identification of CUL4A-DDB1-WDFY1 as an E3 ubiquitin ligase complex involved in initiation of lysophagy
    1
    1. scibot 15 Sep 2022
      RRID:AB_1587578

      DOI: 10.1016/j.celrep.2022.111349

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    sciencedirect.com/science/article/pii/S2211124722011779
  23. Aug 2022
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
    1
    1. scibot 13 Aug 2022
      RRID:AB_1587578

      DOI: 10.1016/j.cell.2016.07.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC5002269/
  25. Jun 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Supramolecular assembly of GSK3α as a cellular response to amino acid starvation
    1
    1. scibot 22 Jun 2022
      RRID:AB_1587578

      DOI: 10.1016/j.molcel.2022.05.025

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    sciencedirect.com/science/article/pii/S1097276522004920
  27. www.sciencedirect.com www.sciencedirect.com
    Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
    1
    1. scibot 17 Jun 2022
      RRID:AB_1587578

      DOI: 10.1016/j.isci.2022.104519

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    sciencedirect.com/science/article/pii/S2589004222007908
  28. Mar 2022
  29. www.embopress.org www.embopress.org
    K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation
    1
    1. scibot 31 Mar 2022
      RRID:AB_1587578

      DOI: 10.15252/embj.2021110145

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    embopress.org/doi/abs/10.15252/embj.2021110145
  30. www.sciencedirect.com www.sciencedirect.com
    A trio of ubiquitin ligases sequentially drives ubiquitylation and autophagic degradation of dysfunctional yeast proteasomes
    1
    1. scibot 18 Mar 2022
      RRID:AB_1587578

      DOI: 10.1016/j.celrep.2022.110535

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    sciencedirect.com/science/article/pii/S2211124722002765
  31. www.sciencedirect.com www.sciencedirect.com
    The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity
    1
    1. scibot 09 Mar 2022
      RRID:AB_1587578

      DOI: 10.1016/j.celrep.2022.110434

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    sciencedirect.com/science/article/pii/S2211124722001619
  32. www.sciencedirect.com www.sciencedirect.com
    Linkage reprogramming by tailor-made E3s reveals polyubiquitin chain requirements in DNA-damage bypass
    1
    1. scibot 09 Mar 2022
      RRID:AB_1587578

      DOI: 10.1016/j.molcel.2022.02.016

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    sciencedirect.com/science/article/pii/S1097276522001393
  33. Jan 2022
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myeloid Fbxw7 Prevents Pulmonary Fibrosis by Suppressing TGF-β Production
    1
    1. scibot 22 Jan 2022
      RRID:AB_1587578

      DOI: 10.3389/fimmu.2021.760138

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    ncbi.nlm.nih.gov/pmc/articles/PMC8767095/
  35. Oct 2021
  36. www.sciencedirect.com www.sciencedirect.com
    TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease
    1
    1. scibot 13 Oct 2021
      RRID:AB_1587578

      DOI: 10.1016/j.neuron.2021.09.031

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    sciencedirect.com/science/article/pii/S0896627321007042
  37. Sep 2021
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease
    1
    1. scibot 22 Sep 2021
      RRID:AB_1587578

      DOI: 10.1016/j.celrep.2021.109754

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    ncbi.nlm.nih.gov/pmc/articles/PMC8423903/
  39. Aug 2021
  40. www.nature.com www.nature.com
    Rewiring of the ubiquitinated proteome determines ageing in C. elegans
    1
    1. scibot 15 Aug 2021
      RRID:AB_1587578

      DOI: 10.1038/s41586-021-03781-z

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    nature.com/articles/s41586-021-03781-z
  41. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 12 Aug 2021
      RRID:AB_1587578

      DOI: 10.1016/j.chom.2017.09.007

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    sciencedirect.com/science/article/pii/S1931312817303955
  42. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 10 Aug 2021
      RRID:AB_1587578

      DOI: 10.1016/j.molcel.2018.11.015

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    sciencedirect.com/science/article/pii/S1097276518309857
  43. www.embopress.org www.embopress.org
    Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway
    1
    1. scibot 07 Aug 2021
      RRID:AB_1587578

      DOI: 10.15252/embj.2020107413

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    embopress.org/doi/abs/10.15252/embj.2020107413
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 06 Aug 2021
      RRID:AB_1587578

      DOI: 10.1016/j.celrep.2019.04.015

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    ncbi.nlm.nih.gov/pmc/articles/PMC6508666/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 02 Aug 2021
      RRID:AB_1587578

      DOI: 10.7554/eLife.24425

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    ncbi.nlm.nih.gov/pmc/articles/PMC5484619/
  46. Jul 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death
    1
    1. scibot 31 Jul 2021
      Rabbit monoclonal anti-K48 Ubiquitin

      DOI: 10.1016/j.celrep.2019.11.014

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    sciencedirect.com/science/article/pii/S2211124719314858
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 29 Jul 2021
      RRID:AB_1587578

      DOI: 10.1016/j.chom.2017.09.007

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    ncbi.nlm.nih.gov/pmc/articles/PMC5644667/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 29 Jul 2021
      RRID:AB_1587578

      DOI: 10.7554/eLife.21465

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    ncbi.nlm.nih.gov/pmc/articles/PMC5370187/
  50. elifesciences.org elifesciences.org
    Chlamydia trachomatis-containing vacuole serves as deubiquitination platform to stabilize Mcl-1 and to interfere with host defense
    1
    1. scibot 27 Jul 2021
      AB_1587578

      DOI: 10.7554/eLife.21465

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    elifesciences.org/content/6/e21465
  51. rupress.org rupress.org
    Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination
    1
    1. scibot 23 Jul 2021
      05-1307

      DOI: 10.1083/jcb.202006043

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    rupress.org/jcb/article/220/6/e202006043/211984/Parkin-independent-mitophagy-via-Drp1-mediated
  52. May 2021
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ architecture of neuronal α-Synuclein inclusions
    1
    1. scibot 05 May 2021
      RRID:AB_1587578

      DOI: 10.1038/s41467-021-22108-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC8046968/
  54. Apr 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome
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    1. scibot 23 Apr 2021
      RRID:AB_1587578

      DOI: 10.1016/j.cell.2021.03.048

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    sciencedirect.com/science/article/pii/S0092867421003792
  56. Feb 2021
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Raloxifene is a female-specific proteostasis therapeutic in the spinal cord
    1
    1. scibot 27 Feb 2021
      RRID:AB_1587578

      DOI: 10.1210/endocr/bqaa221

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    ncbi.nlm.nih.gov/pmc/articles/PMC7774777/
  58. Sep 2020
  59. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Regulation of the 26S Proteasome
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    1. scibot 17 Sep 2020
      RRID:AB_1587578

      DOI: 10.1016/j.celrep.2020.108059

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    sciencedirect.com/science/article/pii/S2211124720310445
  60. rupress.org rupress.org
    Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy
    1
    1. scibot 08 Sep 2020
      RRID:AB_1587578

      DOI: 10.1083/jcb.201912144

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      Curator: @evieth

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    rupress.org/jcb/article/219/9/e201912144/151863/Critical-role-of-mitochondrial-ubiquitination-and
  61. www.sciencedirect.com www.sciencedirect.com
    Auto-ubiquitination of NEDD4-1 Recruits USP13 to Facilitate Autophagy through Deubiquitinating VPS34
    1
    1. scibot 06 Sep 2020
      RRID:AB_1587578

      DOI: 10.1016/j.celrep.2020.01.088

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    sciencedirect.com/science/article/pii/S2211124720301224
  62. www.sciencedirect.com www.sciencedirect.com
    Vimentin Coordinates Protein Turnover at the Aggresome during Neural Stem Cell Quiescence Exit
    1
    1. scibot 04 Sep 2020
      K48-linked Polyubiquitin

      DOI: 10.1016/j.stem.2020.01.018

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1934590920300187
  63. www.sciencedirect.com www.sciencedirect.com
    Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28
    1
    1. scibot 03 Sep 2020
      Ubiquitin-K48

      DOI: 10.1016/j.molcel.2019.12.023

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  64. www.sciencedirect.com www.sciencedirect.com
    Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair
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      RRID:AB_1587578

      DOI: 10.1016/j.cell.2020.02.010

      Resource: (Millipore Cat# 05-1307, RRID:AB_1587578)

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    sciencedirect.com/science/article/pii/S0092867420301549
  65. Jan 2020
  66. www.sciencedirect.com www.sciencedirect.com
    Structural Basis for the Inhibitory Effects of Ubistatins in the Ubiquitin-Proteasome Pathway
    1
    1. scibot 13 Jan 2020
      RRID:AB_1587578

      DOI: 10.1016/j.str.2017.10.007

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  67. www.embopress.org www.embopress.org
    The p97–Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8
    1
    1. scibot 13 Jan 2020
      RRID:AB_1587578

      DOI: 10.15252/embj.2019102361

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  68. Nov 2018
  69. europepmc.org europepmc.org
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    1. scibot 05 Nov 2018
      RRID:AB_1587578

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    europepmc.org/articles/PMC5644667/
  70. Nov 2017
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC5640506/
  72. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling
    1
    1. scibot 08 Nov 2017
      RRID:AB_1587578

      Curator: @Jmenke

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  73. www.sciencedirect.com www.sciencedirect.com
    Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy
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    1. scibot 08 Nov 2017
      AB_1587578

      Curator: @chewbeccax

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  74. europepmc.org europepmc.org
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      AB_1587578

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    europepmc.org/articles/PMC5002269/table/undtbl1/
  75. elifesciences.org elifesciences.org
    Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses
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    1. scibot 08 Nov 2017
      AB_1587578

      Curator: @chewbeccax

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    elifesciences.org/articles/24425
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      AB_1587578

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  77. www.cell.com www.cell.com
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      AB_1587578

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  78. www.sciencedirect.com www.sciencedirect.com
    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
    1
    1. scibot 08 Nov 2017
      AB_1587578

      Curator: @gabimpine

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      RRID:AB_1587578 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867416309266