52 Matching Annotations
  1. Jun 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Bacterial esterases reverse lipopolysaccharide ubiquitylation to block host immunity
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.chom.2024.04.012

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    sciencedirect.com/science/article/pii/S193131282400132X
  3. Apr 2024
  4. link.springer.com link.springer.com
    Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation
    1
    1. scibot 24 Apr 2024
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      DOI: 10.1038/s41594-024-01294-7

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    link.springer.com/article/10.1038/s41594-024-01294-7
  5. www.sciencedirect.com www.sciencedirect.com
    Individual Atg8 paralogs and a bacterial metabolite sequentially promote hierarchical CASM-xenophagy induction and transition
    1
    1. scibot 24 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114131

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    sciencedirect.com/science/article/pii/S2211124724004595
  6. Feb 2024
  7. www.biorxiv.org www.biorxiv.org
    Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation
    1
    1. scibot 15 Feb 2024
      RRID:AB_1587580

      DOI: 10.1101/2023.12.20.572718

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    biorxiv.org/content/10.1101/2023.12.20.572718v1
  8. www.sciencedirect.com www.sciencedirect.com
    Prenatal hormone stress triggers embryonic cardiac hypertrophy outcome by ubiquitin-dependent degradation of mitochondrial mitofusin 2
    1
    1. scibot 09 Feb 2024
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      DOI: 10.1016/j.isci.2023.108690

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    sciencedirect.com/science/article/pii/S2589004223027670
  9. Dec 2023
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62
    1
    1. scibot 22 Dec 2023
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      DOI: 10.1038/s41467-023-44033-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC10730909/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquiton—An inducible, linkage-specific polyubiquitylation tool
    1
    1. scibot 16 Dec 2023
      RRID:AB_1587580

      DOI: 10.1016/j.molcel.2023.11.016

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    ncbi.nlm.nih.gov/pmc/articles/PMC10804999/
  12. Nov 2023
  13. www.sciencedirect.com www.sciencedirect.com
    The ubiquitin conjugase Rad6 mediates ribosome pausing during oxidative stress
    1
    1. scibot 03 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113359

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    sciencedirect.com/science/article/pii/S2211124723013712
  14. Oct 2023
  15. www.biorxiv.org www.biorxiv.org
    Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival
    1
    1. scibot 13 Oct 2023
      RRID:AB_1587580

      DOI: 10.1101/2023.10.06.560832

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    biorxiv.org/content/10.1101/2023.10.06.560832v1
  16. Aug 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Art2 mediates selective endocytosis of methionine transporters during adaptation to sphingolipid depletion
    1
    1. scibot 05 Aug 2023
      RRID:AB_1587580

      DOI: 10.1242/jcs.260675

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    ncbi.nlm.nih.gov/pmc/articles/PMC10399987/
  18. www.sciencedirect.com www.sciencedirect.com
    Senescent cells form nuclear foci that contain the 26S proteasome
    1
    1. scibot 04 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112880

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    sciencedirect.com/science/article/pii/S2211124723008914
  19. Jul 2023
  20. 52.53.155.43 52.53.155.43
    NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-condensation with p62
    1
    1. scibot 19 Jul 2023
      RRID:AB_1587580

      DOI: 10.1101/2023.06.05.543428

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    52.53.155.43/5185b06857919afc7fae38712332798a8a903a3a/2023.06.05.543428v1.full-html.html
  21. Feb 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Loss of C9orf72 perturbs the Ran-GTPase gradient and nucleocytoplasmic transport, generating compositionally diverse Importin β-1 granules
    1
    1. scibot 24 Feb 2023
      RRID:AB_1587580

      DOI: 10.1016/j.celrep.2023.112134

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    sciencedirect.com/science/article/pii/S2211124723001456
  23. www.nature.com www.nature.com
    The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
    1
    1. scibot 04 Feb 2023
      RRID:AB_1587580

      DOI: 10.1038/s41467-023-36058-2

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    nature.com/articles/s41467-023-36058-2
  24. Nov 2022
  25. www.embopress.org www.embopress.org
    LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus
    1
    1. scibot 19 Nov 2022
      RRID:AB_1587580

      DOI: 10.15252/embj.2022112006

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    embopress.org/doi/10.15252/embj.2022112006
  26. Oct 2022
  27. www.nature.com www.nature.com
    The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma
    1
    1. scibot 18 Oct 2022
      AB_1587580

      DOI: 10.1038/s41419-022-05318-2

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    nature.com/articles/s41419-022-05318-2
  28. Sep 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Identification of CUL4A-DDB1-WDFY1 as an E3 ubiquitin ligase complex involved in initiation of lysophagy
    1
    1. scibot 15 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111349

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    sciencedirect.com/science/article/pii/S2211124722011779
  30. www.sciencedirect.com www.sciencedirect.com
    The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction
    1
    1. scibot 11 Sep 2022
      RRID:AB_1587580

      DOI: 10.1016/j.chom.2022.08.008

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    sciencedirect.com/science/article/pii/S1931312822004073
  31. Aug 2022
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
    1
    1. scibot 13 Aug 2022
      RRID:AB_1587580

      DOI: 10.1016/j.cell.2016.07.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC5002269/
  33. May 2022
  34. www.sciencedirect.com www.sciencedirect.com
    Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes
    1
    1. scibot 26 May 2022
      RRID:AB_1587580

      DOI: 10.1016/j.celrep.2022.110860

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    sciencedirect.com/science/article/pii/S2211124722006337
  35. Mar 2022
  36. www.sciencedirect.com www.sciencedirect.com
    A trio of ubiquitin ligases sequentially drives ubiquitylation and autophagic degradation of dysfunctional yeast proteasomes
    1
    1. scibot 18 Mar 2022
      RRID:AB_1587580

      DOI: 10.1016/j.celrep.2022.110535

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    sciencedirect.com/science/article/pii/S2211124722002765
  37. www.sciencedirect.com www.sciencedirect.com
    Linkage reprogramming by tailor-made E3s reveals polyubiquitin chain requirements in DNA-damage bypass
    1
    1. scibot 09 Mar 2022
      RRID:AB_1587580

      DOI: 10.1016/j.molcel.2022.02.016

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    sciencedirect.com/science/article/pii/S1097276522001393
  38. Oct 2021
  39. www.sciencedirect.com www.sciencedirect.com
    TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease
    1
    1. scibot 13 Oct 2021
      RRID:AB_1587580

      DOI: 10.1016/j.neuron.2021.09.031

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    sciencedirect.com/science/article/pii/S0896627321007042
  40. www.sciencedirect.com www.sciencedirect.com
    Humanin-induced autophagy plays important roles in skeletal muscle function and lifespan extension
    1
    1. scibot 12 Oct 2021
      05–1308

      DOI: 10.1016/j.bbagen.2021.130017

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    sciencedirect.com/science/article/pii/S0304416521001768
  41. www.sciencedirect.com www.sciencedirect.com
    Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains
    1
    1. scibot 06 Oct 2021
      RRID:AB_1587580

      DOI: 10.1016/j.celrep.2021.109777

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    sciencedirect.com/science/article/pii/S2211124721012316
  42. Aug 2021
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 13 Aug 2021
      RRID:AB_1587580

      DOI: 10.1016/j.celrep.2019.04.015

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    ncbi.nlm.nih.gov/pmc/articles/PMC6508666/
  44. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 12 Aug 2021
      RRID:AB_1587580

      DOI: 10.1016/j.celrep.2019.02.067

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    sciencedirect.com/science/article/pii/S2211124719302463
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 09 Aug 2021
      RRID:AB_1587580

      DOI: 10.7554/eLife.22416

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    ncbi.nlm.nih.gov/pmc/articles/PMC5340530/
  46. www.nature.com www.nature.com
    Rewiring of the ubiquitinated proteome determines ageing in C. elegans
    1
    1. scibot 07 Aug 2021
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      DOI: 10.1038/s41586-021-03781-z

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    nature.com/articles/s41586-021-03781-z
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 02 Aug 2021
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      DOI: 10.7554/eLife.24425

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    ncbi.nlm.nih.gov/pmc/articles/PMC5484619/
  48. Jul 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death
    1
    1. scibot 31 Jul 2021
      Rabbit monoclonal anti-K63 Ubiquitin

      DOI: 10.1016/j.celrep.2019.11.014

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    sciencedirect.com/science/article/pii/S2211124719314858
  50. rupress.org rupress.org
    Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination
    1
    1. scibot 23 Jul 2021
      05-1308

      DOI: 10.1083/jcb.202006043

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    rupress.org/jcb/article/220/6/e202006043/211984/Parkin-independent-mitophagy-via-Drp1-mediated
  51. Apr 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome
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      DOI: 10.1016/j.cell.2021.03.048

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    sciencedirect.com/science/article/pii/S0092867421003792
  53. Nov 2020
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of ubiquitin Ser57 kinases regulating the oxidative stress response in yeast
    1
    1. scibot 12 Nov 2020
      RRID:AB_1587580

      DOI: 10.7554/eLife.58155

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    ncbi.nlm.nih.gov/pmc/articles/PMC7647399/
  55. Sep 2020
  56. rupress.org rupress.org
    Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy
    1
    1. scibot 11 Sep 2020
      RRID:AB_1587580

      DOI: 10.1083/jcb.201912144

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    rupress.org/jcb/article/219/9/e201912144/151863/Critical-role-of-mitochondrial-ubiquitination-and
  57. genesdev.cshlp.org genesdev.cshlp.org
    Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne
    1
    1. scibot 04 Sep 2020
      K63

      DOI: 10.1101/gad.332395.119

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    genesdev.cshlp.org/content/33/23-24/1702.full
  58. Jan 2020
  59. www.sciencedirect.com www.sciencedirect.com
    Structural Basis for the Inhibitory Effects of Ubistatins in the Ubiquitin-Proteasome Pathway
    1
    1. scibot 13 Jan 2020
      RRID:AB_1587580

      DOI: 10.1016/j.str.2017.10.007

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    sciencedirect.com/science/article/pii/S0969212617303350
  60. www.sciencedirect.com www.sciencedirect.com
    AUTACs: Cargo-Specific Degraders Using Selective Autophagy
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    1. scibot 13 Jan 2020
      RRID:AB_1587580

      DOI: 10.1016/j.molcel.2019.09.009

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    sciencedirect.com/science/article/pii/S109727651930694X
  61. www.embopress.org www.embopress.org
    The p97–Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8
    1
    1. scibot 13 Jan 2020
      RRID:AB_1587580

      DOI: 10.15252/embj.2019102361

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    embopress.org/doi/10.15252/embj.2019102361
  62. www.sciencedirect.com www.sciencedirect.com
    MST1 Negatively Regulates TNFα-Induced NF-κB Signaling through Modulating LUBAC Activity
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  63. Nov 2018
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    Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy
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    Metal Sensing by the IRT1 Transporter-Receptor Orchestrates Its Own Degradation and Plant Metal Nutrition
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    Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability
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  67. Nov 2017
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    Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling
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    Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling
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    Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy
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  71. elifesciences.org elifesciences.org
    Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses
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    YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB
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    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
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