27 Matching Annotations
  1. Jun 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Inhibition of CBX4/7 Hypersensitises Homologous Recombination-Impaired Cancer to Radiation by Compromising CtIP-Mediated DNA End Resection
    1
    1. scibot 15 Jun 2024
      RRID:AB_1603759

      DOI: 10.3390/cancers16112155

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    ncbi.nlm.nih.gov/pmc/articles/PMC11172190/
  3. Jul 2023
  4. www.sciencedirect.com www.sciencedirect.com
    Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein
    1
    1. scibot 27 Jul 2023
      RRID:AB_1603759

      DOI: 10.1016/j.molcel.2023.06.031

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    sciencedirect.com/science/article/pii/S1097276523005075
  5. Jun 2023
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
    1
    1. scibot 17 Jun 2023
      RRID:AB_1603759

      DOI: 10.1016/j.molcel.2022.12.004

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    ncbi.nlm.nih.gov/pmc/articles/PMC7614657/
  7. Nov 2022
  8. www.sciencedirect.com www.sciencedirect.com
    POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells
    1
    1. scibot 18 Nov 2022
      RRID:AB_1603759

      DOI: 10.1016/j.celrep.2022.111716

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    sciencedirect.com/science/article/pii/S2211124722015947
  9. academic.oup.com academic.oup.com
    Multiple-low-dose therapy: effective killing of high-grade serous ovarian cancer cells with ATR and CHK1 inhibitors
    1
    1. scibot 15 Nov 2022
      RRID:AB_1603759

      DOI: 10.1093/narcan/zcac036

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    academic.oup.com/narcancer/article/4/4/zcac036/6825304
  10. Jun 2022
  11. www.sciencedirect.com www.sciencedirect.com
    A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism
    1
    1. scibot 25 Jun 2022
      AB_1603759

      DOI: 10.1016/j.isci.2022.104591

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    sciencedirect.com/science/article/pii/S258900422200863X
  12. Apr 2022
  13. www.sciencedirect.com www.sciencedirect.com
    Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks
    1
    1. scibot 08 Apr 2022
      RRID: AB_1603759

      DOI: 10.1016/j.isci.2022.104142

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      Curator: @sophiastull

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    sciencedirect.com/science/article/pii/S2589004222004126
  14. Feb 2022
  15. www.sciencedirect.com www.sciencedirect.com
    HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia
    1
    1. scibot 18 Feb 2022
      RRID:AB_1603759

      DOI: 10.1016/j.molcel.2022.01.014

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    sciencedirect.com/science/article/pii/S1097276522000570
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sesquiterpene Lactones Potentiate Olaparib-Induced DNA Damage in p53 Wildtype Cancer Cells
    1
    1. scibot 16 Feb 2022
      RRID:AB_1603759

      DOI: 10.3390/ijms23031116

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

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    ncbi.nlm.nih.gov/pmc/articles/PMC8835362/
  17. Nov 2021
  18. www.sciencedirect.com www.sciencedirect.com
    A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization
    1
    1. scibot 18 Nov 2021
      RRID:AB_1603759

      DOI: 10.1016/j.molcel.2021.10.017

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

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    sciencedirect.com/science/article/pii/S1097276521009096
  19. Oct 2021
  20. link.springer.com link.springer.com
    Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models
    1
    1. scibot 19 Oct 2021
      RRID:AB_1603759

      DOI: 10.1186/s13046-021-02124-0

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

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    link.springer.com/article/10.1186/s13046-021-02124-0
  21. Jul 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 29 Jul 2021
      RRID:AB_1603759

      DOI: 10.1016/j.molcel.2018.10.036

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

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    sciencedirect.com/science/article/pii/S1097276518308967
  23. www.sciencedirect.com www.sciencedirect.com
    Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors
    1
    1. scibot 29 Jul 2021
      RRID:AB_1603759

      DOI: 10.1016/j.molcel.2018.02.022

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

      Curator: @Jmenke

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      RRID:AB_1603759 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276518301412
  24. www.sciencedirect.com www.sciencedirect.com
    EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart
    1
    1. scibot 03 Jul 2021
      Ab79398

      DOI: 10.1016/j.molcel.2021.05.027

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

      Curator: @Naa003

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      RRIDCUR:Missing RRID:AB_1603759
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    sciencedirect.com/science/article/pii/S1097276521004202
  25. www.cell.com www.cell.com
    Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency
    1
    1. scibot 03 Jul 2021
      RRID:AB_1603759

      DOI: 10.1016/j.molcel.2021.06.011

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00458-5
  26. May 2021
  27. www.sciencedirect.com www.sciencedirect.com
    Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells
    1
    1. scibot 07 May 2021
      RRID:AB_1603759

      DOI: 10.1016/j.molcel.2020.07.010

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

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    sciencedirect.com/science/article/pii/S1097276520304767
  28. www.sciencedirect.com www.sciencedirect.com
    Homology-directed repair protects the replicating genome from metabolic assaults
    1
    1. scibot 06 May 2021
      RRID:AB_1603759

      DOI: 10.1016/j.devcel.2021.01.011

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

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    sciencedirect.com/science/article/pii/S1534580721000691
  29. Mar 2021
  30. www.sciencedirect.com www.sciencedirect.com
    TRPS1 drives heterochromatic origin refiring and cancer genome evolution
    1
    1. scibot 10 Mar 2021
      RRID:AB_1603759

      DOI: 10.1016/j.celrep.2021.108814

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S2211124721001285
  31. Sep 2020
  32. www.sciencedirect.com www.sciencedirect.com
    Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication
    1
    1. scibot 26 Sep 2020
      RRID:AB_1603759

      DOI: 10.1016/j.celrep.2020.01.067

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

      Curator: @ethanbadger

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      RRID:AB_1603759 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720300929
  33. www.sciencedirect.com www.sciencedirect.com
    The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency
    1
    1. scibot 13 Sep 2020
      RRID:AB_1603759

      DOI: 10.1016/j.celrep.2020.107985

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

      Curator: @Naa003

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      RRID:AB_1603759 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720309700
  34. www.sciencedirect.com www.sciencedirect.com
    The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells
    1
    1. scibot 09 Sep 2020
      RRID:AB_1603759

      DOI: 10.1016/j.celrep.2020.107849

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:AB_1603759
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    sciencedirect.com/science/article/pii/S2211124720308305
  35. Jan 2020
  36. www.sciencedirect.com www.sciencedirect.com
    RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_1603759

      DOI: 10.1016/j.chembiol.2019.12.005

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

      Curator: @ethanbadger

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      RRID:AB_1603759 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2451945619304015
  37. www.sciencedirect.com www.sciencedirect.com
    ATR Signaling Uncouples the Role of RAD51 Paralogs in Homologous Recombination and Replication Stress Response
    1
    1. scibot 13 Jan 2020
      RRID:AB_1603759

      DOI: 10.1016/j.celrep.2019.09.008

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

      Curator: @ethanbadger

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      RRID:AB_1603759 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719311854
  38. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:AB_1603759

      DOI: 10.1016/j.molcel.2018.11.036

      Resource: (Abcam Cat# ab79398, RRID:AB_1603759)

      Curator: @evieth

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      RRID:AB_1603759 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276518310062
  39. www.sciencedirect.com www.sciencedirect.com
    DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors
    1
    1. scibot 13 Jan 2020
      RRID:AB_1603759

      DOI: 10.1016/j.ccell.2019.02.004

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      Curator: @ethanbadger

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      RRID:AB_1603759 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610819300996
  40. Nov 2018
  41. www.sciencedirect.com www.sciencedirect.com
    BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency
    1
    1. scibot 05 Nov 2018
      RRID:AB_1603759

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      (Abcam Cat# ab79398, RRID:AB_1603759)

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    sciencedirect.com/science/article/pii/S1535610818300199
  42. Nov 2017
  43. www.sciencedirect.com www.sciencedirect.com
    RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health
    1
    1. scibot 08 Nov 2017
      AB_1603759

      Curator: @Zeljana_Babic

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      (Abcam Cat# ab79398, RRID:AB_1603759)

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      RRID:AB_1603759 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517302770