36 Matching Annotations
  1. Sep 2024
  2. www.cell.com www.cell.com
    TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival
    1
    1. scibot 12 Sep 2024
      AB_1640207

      DOI: 10.1016/j.cell.2024.08.020

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    cell.com/cell/fulltext/S0092-8674(24)00911-5
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Aberrantly Overexpressed Polo-like Kinase 4 Is a Potential Effective Treatment for DNA Damage Repair–Deficient Uterine Leiomyosarcoma
    1
    1. scibot 05 Sep 2024
      RRID:AB_1640207

      DOI: 10.1158/1078-0432.CCR-23-3720

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    ncbi.nlm.nih.gov/pmc/articles/PMC11369621/
  4. Jul 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YZL-51N functions as a selective inhibitor of SIRT7 by NAD+ competition to impede DNA damage repair
    1
    1. scibot 01 Jul 2024
      RRID:AB_1640207

      DOI: 10.1016/j.isci.2024.110014

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    ncbi.nlm.nih.gov/pmc/articles/PMC11214487/
  6. May 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations
    1
    1. scibot 23 May 2024
      RRID:AB_1640207

      DOI: 10.1016/j.xcrm.2024.101578

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    sciencedirect.com/science/article/pii/S2666379124002702
  8. Apr 2024
  9. www.sciencedirect.com www.sciencedirect.com
    DNA-PK and ATM drive phosphorylation signatures that antagonistically regulate cytokine responses to herpesvirus infection or DNA damage
    2
    1. scibot 12 Apr 2024
      RRID:AB_1640207

      DOI: 10.1016/j.cels.2024.03.003

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    2. scibot 12 Apr 2024
      RRID:AB_1640207

      DOI: 10.1016/j.cels.2024.03.003

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    sciencedirect.com/science/article/pii/S2405471224000887
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma
    1
    1. scibot 03 Apr 2024
      RRID:AB_1640207

      DOI: 10.1158/1078-0432.CCR-23-1003

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    ncbi.nlm.nih.gov/pmc/articles/PMC10592192/
  11. Mar 2024
  12. www.sciencedirect.com www.sciencedirect.com
    SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis
    2
    1. scibot 22 Mar 2024
      RRID:AB_1640207

      DOI: 10.1016/j.celrep.2024.113975

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    2. scibot 22 Mar 2024
      RRID:AB_1640207

      DOI: 10.1016/j.celrep.2024.113975

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    sciencedirect.com/science/article/pii/S2211124724003036
  13. www.sciencedirect.com www.sciencedirect.com
    Disruption of H3K36 methylation provokes cellular plasticity to drive aberrant glandular formation and squamous carcinogenesis
    2
    1. scibot 06 Mar 2024
      RRID:AB_1640207

      DOI: 10.1016/j.devcel.2023.12.007

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    2. scibot 06 Mar 2024
      RRID:AB_1640207

      DOI: 10.1016/j.devcel.2023.12.007

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    sciencedirect.com/science/article/pii/S1534580723006573
  14. Jan 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells
    1
    1. scibot 19 Jan 2024
      RRID:AB_1640207

      DOI: 10.1016/j.xcrm.2023.101376

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    sciencedirect.com/science/article/pii/S2666379123006055
  16. Nov 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma
    1
    1. scibot 02 Nov 2023
      RRID:AB_1640207

      DOI: 10.1016/j.celrep.2023.113307

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    sciencedirect.com/science/article/pii/S2211124723013190
  18. Jun 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability
    1
    1. scibot 09 Jun 2023
      RRID:AB_1640207

      DOI: 10.1016/j.molcel.2023.05.015

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    sciencedirect.com/science/article/pii/S1097276523003714
  20. Mar 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drug–gene Interaction Screens Coupled to Tumor Data Analyses Identify the Most Clinically Relevant Cancer Vulnerabilities Driving Sensitivity to PARP Inhibition
    1
    1. scibot 29 Mar 2023
      RRID:AB_1640207

      DOI: 10.1158/2767-9764.CRC-22-0119

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    ncbi.nlm.nih.gov/pmc/articles/PMC10035383/
  22. Oct 2022
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BK Polyomavirus Requires the Mismatch Repair Pathway for DNA Damage Response Activation
    1
    1. scibot 12 Oct 2022
      RRID:AB_1640207

      DOI: 10.1128/jvi.02028-21

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    ncbi.nlm.nih.gov/pmc/articles/PMC9044952/
  24. May 2022
  25. www.sciencedirect.com www.sciencedirect.com
    DNA damage promotes HLA class I presentation by stimulating a pioneer round of translation-associated antigen production
    1
    1. scibot 20 May 2022
      RRID:AB_1640207

      DOI: 10.1016/j.molcel.2022.04.030

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    sciencedirect.com/science/article/pii/S1097276522003938
  26. Apr 2022
  27. www.sciencedirect.com www.sciencedirect.com
    Heterochromatic repeat clustering imposes a physical barrier on homologous recombination to prevent chromosomal translocations
    1
    1. scibot 21 Apr 2022
      RRID:AB_1640207

      DOI: 10.1016/j.molcel.2022.03.033

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    sciencedirect.com/science/article/pii/S1097276522002891
  28. Dec 2021
  29. www.sciencedirect.com www.sciencedirect.com
    The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability
    1
    1. scibot 09 Dec 2021
      RRID:AB_1640207

      DOI: 10.1016/j.celrep.2021.110080

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    sciencedirect.com/science/article/pii/S2211124721015710
  30. Nov 2021
  31. www.cell.com www.cell.com
    MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts
    1
    1. scibot 30 Nov 2021
      RRID:AB_1640207

      DOI: 10.1016/j.molcel.2021.11.002

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00952-7
  32. Aug 2021
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Epigenetic Dysregulation Induces Translocation of Histone H3 into Cytoplasm
    1
    1. scibot 15 Aug 2021
      AB_1640207

      DOI: 10.1002/advs.202100779

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    onlinelibrary.wiley.com/doi/10.1002/advs.202100779
  34. Jun 2021
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability
    1
    1. scibot 18 Jun 2021
      RRID:AB_1640207

      DOI: 10.1016/j.isci.2021.102534

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    ncbi.nlm.nih.gov/pmc/articles/PMC8184511/
  36. May 2021
  37. www.sciencedirect.com www.sciencedirect.com
    AHNAK controls 53BP1-mediated p53 response by restraining 53BP1 oligomerization and phase separation
    1
    1. scibot 09 May 2021
      RRID:AB_1640207

      DOI: 10.1016/j.molcel.2021.04.010

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    sciencedirect.com/science/article/pii/S1097276521003154
  38. www.sciencedirect.com www.sciencedirect.com
    The ZATT-TOP2A-PICH Axis Drives Extensive Replication Fork Reversal to Promote Genome Stability
    1
    1. scibot 08 May 2021
      AB_1640207

      DOI: 10.1016/j.molcel.2020.11.007

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    sciencedirect.com/science/article/pii/S1097276520307851
  39. Feb 2021
  40. www.sciencedirect.com www.sciencedirect.com
    A FOXO-dependent replication checkpoint restricts proliferation of damaged cells
    1
    1. scibot 24 Feb 2021
      AB_81292

      DOI: 10.1016/j.celrep.2020.108675

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      Curator: @Naa003

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    sciencedirect.com/science/article/pii/S2211124720316648
  41. elifesciences.org elifesciences.org
    The human origin recognition complex is essential for pre-RC assembly, mitosis, and maintenance of nuclear structure
    1
    1. scibot 24 Feb 2021
      RRID:AB_1640207

      DOI: 10.7554/eLife.61797

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      Curator: @evieth

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    elifesciences.org/articles/61797
  42. www.nature.com www.nature.com
    Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51
    1
    1. scibot 09 Feb 2021
      RRID:AB_1640207

      DOI: 10.1038/s41418-020-00733-4

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      Curator: @evieth

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    nature.com/articles/s41418-020-00733-4
  43. Jan 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A
    1
    1. scibot 27 Jan 2021
      RRID:AB_1640207

      DOI: 10.1016/j.celrep.2020.108680

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    sciencedirect.com/science/article/pii/S2211124720316697
  45. www.sciencedirect.com www.sciencedirect.com
    A FOXO-dependent replication checkpoint restricts proliferation of damaged cells
    1
    1. scibot 27 Jan 2021
      RRID:AB_1640207

      DOI: 10.1016/j.celrep.2020.108675

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    sciencedirect.com/science/article/pii/S2211124720316648
  46. Sep 2020
  47. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome
    1
    1. scibot 25 Sep 2020
      RRID:AB_1640207

      DOI: 10.1016/j.celrep.2020.108179

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    pubmed.ncbi.nlm.nih.gov/32966779/
  48. www.sciencedirect.com www.sciencedirect.com
    METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation
    1
    1. scibot 23 Sep 2020
      RRID:AB_1640207

      DOI: 10.1016/j.molcel.2020.06.017

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    sciencedirect.com/science/article/pii/S1097276520304020
  49. www.sciencedirect.com www.sciencedirect.com
    Pulsatile MAPK Signaling Modulates p53 Activity to Control Cell Fate Decisions at the G2 Checkpoint for DNA Damage
    1
    1. scibot 08 Sep 2020
      RRID:AB_1640207

      DOI: 10.1016/j.celrep.2020.01.074

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2211124720300991
  50. Jan 2020
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis
    1
    1. scibot 13 Jan 2020
      RRID:AB_1640207

      DOI: 10.1016/j.celrep.2019.08.085

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    ncbi.nlm.nih.gov/pmc/articles/PMC6880866/
  52. Nov 2018
  53. www.sciencedirect.com www.sciencedirect.com
    MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation
    1
    1. scibot 05 Nov 2018
      RRID:AB_1640207

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    sciencedirect.com/science/article/pii/S1535610818302691
  54. Nov 2017
  55. www.sciencedirect.com www.sciencedirect.com
    ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks
    1
    1. scibot 08 Nov 2017
      RRID:AB_1640207

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276517306184
  56. www.sciencedirect.com www.sciencedirect.com
    A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability
    1
    1. scibot 08 Nov 2017
      AB_1640207

      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S0092867417305378