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Systematic CRISPR screens decode regulators of primary human pathogenic Th17 cell differentiation and activation

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1. scibot 14 Nov 2026
  
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  DOI: 10.1016/j.isci.2026.118180
  
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sciencedirect.com/science/article/pii/S2589004226035637
Sep 2026
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Preferential engagement of the anti-inflammatory ATP/adenosine axis by HIV vaccine candidate with V1-deleted envelope in male rhesus macaques

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  DOI: 10.1016/j.xcrm.2026.103022
  
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sciencedirect.com/science/article/pii/S2666379126004398
Aug 2026
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Group 2 innate lymphoid cells activate myelin-reactive T cells to augment neuroinflammation

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1. scibot 09 Aug 2026
  
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  DOI: 10.1016/j.immuni.2026.07.011
  
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sciencedirect.com/science/article/pii/S1074761326003109
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tissue and CD4 T cell subset dependence on the amino acid transporter SLC38A1

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1. scibot 24 Mar 2026
  
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  DOI: 10.1016/j.cmet.2026.02.016
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13020643/
Nov 2025
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The transcription factor NFIL3 drives innate lymphoid cell specification from lymphoid progenitors

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1. scibot 01 Nov 2025
  
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  DOI: 10.1016/j.immuni.2025.10.005
  
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sciencedirect.com/science/article/pii/S1074761325004352
Jul 2025
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1-s2.0-S2589004225014440-main-html.html

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1. scibot 24 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113183
  
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52.53.155.43/d0106ead5bb884ca4d13dcd7bae2505050d152dc/1-s2.0-S2589004225014440-main-html.html
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Oxidized Phospholipid oxPAPC Alters Regulatory T-Cell Differentiation and Decreases Their Protective Function in Atherosclerosis in Mice

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1. scibot 04 Jul 2025
  
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  DOI: 10.1161/ATVBAHA.123.319674
  
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ahajournals.org/doi/10.1161/ATVBAHA.123.319674
Mar 2025
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Microbiota-produced immune regulatory bile acid metabolites control central nervous system autoimmunity

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102028
  
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sciencedirect.com/science/article/pii/S2666379125001016
Jan 2025
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1-s2.0-S2589004225000720-main-html.html

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1. scibot 23 Jan 2025
  
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  DOI: 10.1016/j.isci.2025.111812
  
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52.53.155.43/f4fe749bda5943afa72c94738ad741d8e2a2f94c/1-s2.0-S2589004225000720-main-html.html
Dec 2024
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Prenatal antibiotics reduce breast milk IgA and induce dysbiosis in mouse offspring, increasing neonatal susceptibility to bacterial sepsis

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.chom.2024.11.001
  
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sciencedirect.com/science/article/pii/S1931312824004074
Sep 2024
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IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis

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1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.cmet.2024.08.012
  
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sciencedirect.com/science/article/pii/S1550413124003644
Jul 2024
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Protection from environmental enteric dysfunction and growth improvement in malnourished newborns by amplification of secretory IgA

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1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.xcrm.2024.101639
  
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TNF compromises intestinal bile-acid tolerance dictating colitis progression and limited infliximab response

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.cmet.2024.06.008
  
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sciencedirect.com/science/article/pii/S155041312400233X
May 2024
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T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells

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1. scibot 23 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114258
  
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sciencedirect.com/science/article/pii/S2211124724005862
Dec 2023
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Generation of human ILC3 from allogeneic and autologous CD34+ hematopoietic progenitors toward adoptive transfer

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1. scibot 29 Dec 2023
  
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  DOI: 10.1016/j.jcyt.2023.11.011
  
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sciencedirect.com/science/article/pii/S146532492301126X
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IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis

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1. scibot 02 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113508
  
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sciencedirect.com/science/article/pii/S2211124723015206
Nov 2023
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Lactobacillus acidophilus-derived indole lactic acid reverses colitis susceptibility in cesarean-born offspring via activation of AhR

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1. scibot 04 Nov 2023
  
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  DOI: 10.1016/j.isci.2023.108279
  
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52.53.155.43/6d3cb369970d6af9ee4a6737bc5efd3ec5f8e04b/1-s2.0-S2589004223023568-main-html.html
Jun 2023
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Mettl3-m6A-Creb1 forms an intrinsic regulatory axis in maintaining iNKT cell pool and functional differentiation

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1. scibot 03 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112584
  
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sciencedirect.com/science/article/pii/S2211124723005958
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The eIF4EBP-eIF4E axis regulates CD4+ T cell differentiation through modulation of T cell activation and metabolism

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1. scibot 16 May 2023
  
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  DOI: 10.1016/j.isci.2023.106683
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10176268/
Apr 2023
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The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries

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1. scibot 20 Apr 2023
  
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  DOI: 10.1016/j.immuni.2023.01.033
  
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sciencedirect.com/science/article/pii/S1074761323000456
Mar 2023
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Gut microbe-derived milnacipran enhances tolerance to gut ischemia/reperfusion injury

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1. scibot 28 Mar 2023
  
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  DOI: 10.1016/j.xcrm.2023.100979
  
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Original research: Invasive margin tissue-resident macrophages of high CD163 expression impede responses to T cell-based immunotherapy

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  DOI: 10.1136/jitc-2022-006433
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10016286/
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Dietary tryptophan deficiency promotes gut RORγt+ Treg cells at the expense of Gata3+ Treg cells and alters commensal microbiota metabolism

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1. scibot 03 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112135
  
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sciencedirect.com/science/article/pii/S2211124723001468
Feb 2023
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Repression of the aryl-hydrocarbon receptor prevents oxidative stress and ferroptosis of intestinal intraepithelial lymphocytes

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1. scibot 17 Feb 2023
  
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  DOI: 10.1016/j.immuni.2023.01.023
  
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sciencedirect.com/science/article/pii/S1074761323000353
Jan 2023
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SSRN-id4214938-html.html

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1. scibot 06 Jan 2023
  
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  DOI: 10.1016/j.hlc.2016.10.012
  
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52.53.155.43/810dd42366d0309135ef618e3604051025906006/SSRN-id4214938-html.html
Sep 2022
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Inhibition of Th1 activation and differentiation by dietary guar gum ameliorates experimental autoimmune encephalomyelitis

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  DOI: 10.1016/j.celrep.2022.111328
  
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sciencedirect.com/science/article/pii/S2211124722011561
Nov 2021
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MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function

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1. scibot 12 Nov 2021
  
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  DOI: 10.1016/j.immuni.2021.10.011
  
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Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity

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1. scibot 05 Nov 2021
  
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  DOI: 10.3389/fimmu.2021.726393
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8554290/
Jul 2021
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Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism

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1. scibot 30 Jul 2021
  
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  DOI: 10.1016/j.cell.2018.10.001
  
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sciencedirect.com/science/article/pii/S0092867418313096
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Untitled document

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  DOI: 10.1016/j.immuni.2018.10.012
  
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sciencedirect.com/science/article/pii/S1074761318304771
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Gut microbiota-derived short-chain fatty acids regulate IL-17 production by mouse and human intestinal γδ T cells

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  DOI: 10.1016/j.celrep.2021.109332
  
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sciencedirect.com/science/article/pii/S2211124721007087
Jun 2021
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CD101 genetic variants modify regulatory and conventional T cell phenotypes and functions

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1. scibot 17 Jun 2021
  
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  DOI: 10.1016/j.xcrm.2021.100322
  
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sciencedirect.com/science/article/pii/S2666379121001658
Mar 2021
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Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity

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1. scibot 10 Mar 2021
  
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  DOI: 10.1016/j.celrep.2021.108833
  
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sciencedirect.com/science/article/pii/S2211124721001479
Feb 2021
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Human Fc Receptor-like 3 Inhibits Regulatory T Cell Function and Binds Secretory IgA

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1. scibot 24 Feb 2021
  
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  RRID:AB_1834470
  
  DOI: 10.1016/j.celrep.2019.12.099
  
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sciencedirect.com/science/article/pii/S2211124719317644
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Salt Sensing by Serum/Glucocorticoid-Regulated Kinase 1 Promotes Th17-like Inflammatory Adaptation of Foxp3+ Regulatory T Cells

1
1. scibot 24 Feb 2021
  
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  RRID:AB_1834470
  
  DOI: 10.1016/j.celrep.2020.01.002
  
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cell.com/cell-reports/abstract/S2211-1247(20)30002-4
Jan 2021
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Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia

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1. scibot 31 Jan 2021
  
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  DOI: 10.1016/j.cell.2020.10.048
  
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sciencedirect.com/science/article/pii/S0092867420314550
Dec 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sepsis impedes EAE disease development and diminishes autoantigen-specific naive CD4 T cells

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1. scibot 12 Dec 2020
  
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  AB_1834470
  
  DOI: 10.7554/eLife.55800
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7721438/
Oct 2020
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Microbiota metabolites modulate the T helper 17 to regulatory T cell (Th17/Treg) imbalance promoting resilience to stress-induced anxiety- and depressive-like behaviors

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1. scibot 24 Oct 2020
  
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  RRID:AB_1834470
  
  DOI: 10.1016/j.bbi.2020.10.013
  
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sciencedirect.com/science/article/pii/S0889159120323631
Sep 2020
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Salt Sensing by Serum/Glucocorticoid-Regulated Kinase 1 Promotes Th17-like Inflammatory Adaptation of Foxp3+ Regulatory T Cells

1
1. scibot 16 Sep 2020
  
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  RRID:AB_1834470
  
  DOI: 10.1016/j.celrep.2020.01.002
  
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cell.com/cell-reports/abstract/S2211-1247(20)30002-4
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Human Fc Receptor-like 3 Inhibits Regulatory T Cell Function and Binds Secretory IgA

1
1. scibot 15 Sep 2020
  
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  DOI: 10.1016/j.celrep.2019.12.099
  
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STING Gain-of-Function Disrupts Lymph Node Organogenesis and Innate Lymphoid Cell Development in Mice

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1. scibot 15 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107771
  
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sciencedirect.com/science/article/pii/S2211124720307518
Jan 2020
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Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1834470
  
  DOI: 10.1016/j.celrep.2019.06.024
  
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sciencedirect.com/science/article/pii/S2211124719307909
Nov 2018
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Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3+RORγt+ Regulatory T Cells

1
1. scibot 05 Nov 2018
  
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Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1074761318301468
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Natural Killer Cells Control Tumor Growth by Sensing a Growth Factor

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0092867417313880
Nov 2017
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The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development

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1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S1074761317301875