61 Matching Annotations
  1. Last 7 days
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    Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation
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    1. scibot 07 Jan 2025
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      DOI: 10.1016/j.immuni.2024.12.004

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    sciencedirect.com/science/article/pii/S1074761324005685
  3. Dec 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Expanding GABAergic Neuronal Diversity in iPSC-Derived Disease Models
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      DOI: 10.1101/2024.12.03.626438

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    pmc.ncbi.nlm.nih.gov/articles/PMC11642846/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Determinants of chemoselectivity in ubiquitination by the J2 family of ubiquitin-conjugating enzymes
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      DOI: 10.1038/s44318-024-00301-3

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    pmc.ncbi.nlm.nih.gov/articles/PMC11649903/
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    Design principles to tailor Hsp104 therapeutics
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    sciencedirect.com/science/article/pii/S2211124724013561
  7. Sep 2024
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    Scar/WAVE drives actin protrusions independently of its VCA domain using proline-rich domains
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    sciencedirect.com/science/article/pii/S0960982224011254
  9. Aug 2024
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    The FXR1 network acts as a signaling scaffold for actomyosin remodeling
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    sciencedirect.com/science/article/pii/S009286742400775X
  11. Jul 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging Differentially Affects Axonal Autophagosome Formation and Maturation
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      DOI: 10.1080/15548627.2023.2236485

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    ncbi.nlm.nih.gov/pmc/articles/PMC10621248/
  13. May 2024
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    Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants
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    sciencedirect.com/science/article/pii/S1097276524003277
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    Identification of novel and distinct FGF23 signaling in a Klotho-dependent and -independent manner
    1
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      DOI: 10.1101/2024.01.18.576116

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    biorxiv.org/content/10.1101/2024.01.18.576116v1
  16. Apr 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner
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    sciencedirect.com/science/article/pii/S2211124724004777
  18. Dec 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures
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    1. scibot 28 Dec 2023
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      DOI: 10.3389/fnmol.2023.1323431

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    ncbi.nlm.nih.gov/pmc/articles/PMC10749327/
  20. Nov 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Visualizing the chaperone-mediated folding trajectory of the G protein β5 β-propeller
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    1. scibot 02 Nov 2023
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      DOI: 10.1016/j.molcel.2023.09.032

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    sciencedirect.com/science/article/abs/pii/S1097276523007955
  22. Oct 2023
  23. www.sciencedirect.com www.sciencedirect.com
    The anaphase-promoting complex controls a ubiquitination-phosphoprotein axis in chromatin during neurodevelopment
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      DOI: 10.1016/j.devcel.2023.10.002

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    sciencedirect.com/science/article/pii/S153458072300521X
  24. Aug 2023
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    RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation
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    sciencedirect.com/science/article/abs/pii/S1534580723003659
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10405072/
  27. Jul 2023
  28. www.sciencedirect.com www.sciencedirect.com
    The kinesin Kif21b binds myosin Va and mediates changes in actin dynamics underlying homeostatic synaptic downscaling
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    sciencedirect.com/science/article/pii/S2211124723007544
  29. Feb 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes
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      DOI: 10.1016/j.immuni.2023.01.009

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    ncbi.nlm.nih.gov/pmc/articles/PMC9942873/
  31. www.nature.com www.nature.com
    Mutations in Parkinsonism-linked endocytic proteins synaptojanin1 and auxilin have synergistic effects on dopaminergic axonal pathology
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      DOI: 10.1038/s41531-023-00465-5

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    nature.com/articles/s41531-023-00465-5
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR screening reveals a dependency on ribosome recycling for efficient SARS-CoV-2 programmed ribosomal frameshifting and viral replication
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    ncbi.nlm.nih.gov/pmc/articles/PMC9884621/
  33. Jan 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Zinc-finger protein Zpr1 is a bespoke chaperone essential for eEF1A biogenesis
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      DOI: 10.1016/j.molcel.2022.12.012

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    sciencedirect.com/science/article/pii/S1097276522011698
  35. Dec 2022
  36. www.sciencedirect.com www.sciencedirect.com
    A minimal construct of nuclear-import receptor Karyopherin-β2 defines the regions critical for chaperone and disaggregation activity
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    sciencedirect.com/science/article/pii/S0021925822012492
  37. Jul 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Self-assembly of pericentriolar material in interphase cells lacking centrioles
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      DOI: 10.7554/eLife.77892

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    ncbi.nlm.nih.gov/pmc/articles/PMC9307276/
  39. Jun 2022
  40. elifesciences.org elifesciences.org
    METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance
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      DOI: 10.7554/eLife.72780

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    elifesciences.org/articles/72780
  41. Apr 2022
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    The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade
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      Li-CorCat#926-32219

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    sciencedirect.com/science/article/pii/S1074761322001303
  43. Jan 2022
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The enteric pathogen Cryptosporidium parvum exports proteins into the cytosol of the infected host cell
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      DOI: 10.7554/eLife.70451

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    ncbi.nlm.nih.gov/pmc/articles/PMC8687662/
  45. Dec 2021
  46. www.sciencedirect.com www.sciencedirect.com
    APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain
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    sciencedirect.com/science/article/pii/S1097276521010339
  47. Nov 2021
  48. www.sciencedirect.com www.sciencedirect.com
    DNAJB6b-enriched small extracellular vesicles decrease polyglutamine aggregation in in vitro and in vivo models of Huntington disease
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    sciencedirect.com/science/article/pii/S2589004221012517
  49. Sep 2021
  50. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing
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      DOI: 10.1111/jnc.15491

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15491
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    Oncogene-dependent sloppiness in mRNA translation
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    sciencedirect.com/science/article/pii/S109727652100736X
  52. www.sciencedirect.com www.sciencedirect.com
    Luciferase reporter assays to monitor interferon signaling modulation by SARS-CoV-2 proteins
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      DOI: 10.1016/j.xpro.2021.100781

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    sciencedirect.com/science/article/pii/S2666166721004871
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    An additional NF-κB site allows HIV-1 subtype C to evade restriction by nuclear PYHIN proteins
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      DOI: 10.1016/j.celrep.2021.109735

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    sciencedirect.com/science/article/pii/S2211124721011840
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    Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites
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      DOI: 10.1016/j.chembiol.2021.08.014

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    sciencedirect.com/science/article/pii/S2451945621004037
  55. Aug 2021
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.1210/en.2017-00677

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    ncbi.nlm.nih.gov/pmc/articles/PMC5761600/
  57. Jul 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Elimination of vision-guided target attraction in Aedes aegypti using CRISPR
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      DOI: 10.1016/j.cub.2021.07.003

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    sciencedirect.com/science/article/pii/S0960982221009581
  59. wellcomeopenresearch.org wellcomeopenresearch.org
    Pathogenic <i>FAM83G</i> palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signalling.
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      IRDye 800CW Goat anti-Rat IgG

      DOI: 10.12688/wellcomeopenres.15403.1

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    wellcomeopenresearch.org/articles/4-133
  60. www.nature.com www.nature.com
    FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates
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      DOI: 10.1038/s41598-021-92408-4

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    nature.com/articles/s41598-021-92408-4
  61. Jun 2021
  62. www.frontiersin.org www.frontiersin.org
    NLRP3 Regulates IL-4 Expression in TOX+ CD4+ T Cells of Cutaneous T Cell Lymphoma to Potentially Promote Disease Progression
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      DOI: 10.3389/fimmu.2021.668369

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    frontiersin.org/article/10.3389/fimmu.2021.668369/full
  63. www.sciencedirect.com www.sciencedirect.com
    Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion
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      DOI: 10.1016/j.cell.2021.05.015

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    sciencedirect.com/science/article/pii/S0092867421006322
  64. www.sciencedirect.com www.sciencedirect.com
    ZFP36L1 plays an ambiguous role in the regulation of cell expansion and negatively regulates CDKN1A in chronic myeloid leukemia cells
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      DOI: 10.1016/j.exphem.2021.05.006

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    sciencedirect.com/science/article/pii/S0301472X21001995
  65. May 2021
  66. www.sciencedirect.com www.sciencedirect.com
    Systematic Functional Analysis of SARS-CoV-2 Proteins Uncovers Viral Innate Immune Antagonists and Remaining Vulnerabilities
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    1. scibot 11 May 2021
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      DOI: 10.1016/j.celrep.2021.109126

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    sciencedirect.com/science/article/pii/S2211124721004654
  67. www.sciencedirect.com www.sciencedirect.com
    Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population
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      RRID:AB_1850025

      DOI: 10.1016/j.devcel.2020.10.014

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    sciencedirect.com/science/article/pii/S1534580720308340
  68. Apr 2021
  69. www.sciencedirect.com www.sciencedirect.com
    The bone microenvironment invigorates metastatic seeds for further dissemination
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      RRID:AB_1850025

      DOI: 10.1016/j.cell.2021.03.011

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    sciencedirect.com/science/article/pii/S0092867421002968
  70. www.sciencedirect.com www.sciencedirect.com
    BBLN-1 is essential for intermediate filament organization and apical membrane morphology
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      RRID:AB_1850025

      DOI: 10.1016/j.cub.2021.03.069

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  71. Feb 2021
  72. www.cell.com www.cell.com
    Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins
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      DOI: 10.1016/j.str.2020.12.013

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    cell.com/structure/fulltext/S0969-2126(20)30480-9
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential role of cytosolic Hsp70s in longevity assurance and protein quality control
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      DOI: 10.1371/journal.pgen.1008951

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    ncbi.nlm.nih.gov/pmc/articles/PMC7822560/
  74. Jan 2021
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic genetic variation revealed in diverse Hsp104 homologs
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      DOI: 10.7554/eLife.57457

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  76. Dec 2020
  77. www.sciencedirect.com www.sciencedirect.com
    IFI16 knockdown in primary HIV-1 target cells
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      DOI: 10.1016/j.xpro.2020.100236

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  78. Oct 2020
  79. www.sciencedirect.com www.sciencedirect.com
    Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors
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      DOI: 10.1016/j.chembiol.2020.10.001

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  80. Sep 2020
  81. www.sciencedirect.com www.sciencedirect.com
    Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition
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      DOI: 10.1016/j.celrep.2020.107783

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  82. www.sciencedirect.com www.sciencedirect.com
    β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia
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    1. scibot 16 Sep 2020
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  83. www.sciencedirect.com www.sciencedirect.com
    Genome-wide Nucleotide-Resolution Mapping of DNA Replication Patterns, Single-Strand Breaks, and Lesions by GLOE-Seq
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      DOI: 10.1016/j.molcel.2020.03.027

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    sciencedirect.com/science/article/pii/S1097276520301957
  84. www.sciencedirect.com www.sciencedirect.com
    A Conserved PDZ-Binding Motif in aPKC Interacts with Par-3 and Mediates Cortical Polarity
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    1. scibot 10 Sep 2020
      RRID:AB_1850025

      DOI: 10.1016/j.cub.2019.12.055

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  85. elifesciences.org elifesciences.org
    Oomycete small RNAs bind to the plant RNA-induced silencing complex for virulence
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      DOI: 10.7554/eLife.56096

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    elifesciences.org/articles/56096
  86. www.sciencedirect.com www.sciencedirect.com
    The Alazami Syndrome-Associated Protein LARP7 Guides U6 Small Nuclear RNA Modification and Contributes to Splicing Robustness
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    1. scibot 06 Sep 2020
      RRID:AB_1850025

      DOI: 10.1016/j.molcel.2020.01.001

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  87. www.sciencedirect.com www.sciencedirect.com
    Co-dependent Assembly of Drosophila piRNA Precursor Complexes and piRNA Cluster Heterochromatin
    1
    1. scibot 03 Sep 2020
      IRDye 800CW Goat anti-Rat IgG

      DOI: 10.1016/j.celrep.2018.08.081

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    sciencedirect.com/science/article/pii/S2211124718313858
  88. Jan 2020
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs
    1
    1. scibot 13 Jan 2020
      RRID:AB_1850025

      DOI: 10.7554/eLife.44635

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    ncbi.nlm.nih.gov/pmc/articles/PMC6570481/
  90. www.sciencedirect.com www.sciencedirect.com
    ERK1/2 Phosphorylation of FHOD Connects Signaling and Nuclear Positioning Alternations in Cardiac Laminopathy
    1
    1. scibot 13 Jan 2020
      RRID:AB_1850025

      DOI: 10.1016/j.devcel.2019.10.023

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    sciencedirect.com/science/article/pii/S1534580719308706
  91. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Differing intrinsic biological properties between forebrain and spinal oligodendroglial lineage cells
    1
    1. scibot 13 Jan 2020
      AB_1850025

      DOI: 10.1111/jnc.14074

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14074
  92. Nov 2018
  93. www.sciencedirect.com www.sciencedirect.com
    Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice
    1
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      RRID:AB_1850025

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    sciencedirect.com/science/article/pii/S0896627317309054
  94. academic.oup.com academic.oup.com
    Untitled document
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    academic.oup.com/endo/article/159/1/184/4605126
  95. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Activation of the NLRP3 inflammasome in microglia: the role of ceramide
    1
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      RRID:AB_1850025

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14225/full