33 Matching Annotations
  1. Last 7 days
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    Profound synthetic lethality between SMARCAL1 and FANCM
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    1. scibot 17 Nov 2024
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      DOI: 10.1016/j.molcel.2024.10.016

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    sciencedirect.com/science/article/pii/S1097276524008566
  3. Nov 2024
  4. www.sciencedirect.com www.sciencedirect.com
    A p38 MAPK-ROS axis fuels proliferation stress and DNA damage during CRISPR-Cas9 gene editing in hematopoietic stem and progenitor cells
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    1. scibot 14 Nov 2024
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      DOI: 10.1016/j.xcrm.2024.101823

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    sciencedirect.com/science/article/pii/S2666379124005949
  5. Sep 2024
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    Protocol to study the direct binding of proteins to RNA:DNA hybrids or RNA-DNA chimeras in living cells using cross-linking immunoprecipitation
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    1. scibot 16 Sep 2024
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      DOI: 10.1016/j.xpro.2024.103292

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    sciencedirect.com/science/article/pii/S266616672400457X
  7. Feb 2024
  8. 52.53.155.43 52.53.155.43
    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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    1. scibot 22 Feb 2024
      RRID:AB_185520

      DOI: 10.1101/2023.09.27.559698

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    52.53.155.43/9b07aa3872d935df1f2ff4d73fc96f76996bcf22/2023.09.27.559698v1.full-html.html
  9. Dec 2023
  10. www.sciencedirect.com www.sciencedirect.com
    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
    1
    1. scibot 02 Dec 2023
      RRID:AB_185520

      DOI: 10.1016/j.celrep.2023.113412

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    sciencedirect.com/science/article/pii/S2211124723014249
  11. Oct 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Replication stress and defective checkpoints make fallopian tube epithelial cells putative drivers of high-grade serous ovarian cancer
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    1. scibot 01 Oct 2023
      RRID:AB_185520

      DOI: 10.1016/j.celrep.2023.113144

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    sciencedirect.com/science/article/pii/S2211124723011567
  13. Aug 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1
    1
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.molcel.2023.07.020

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    sciencedirect.com/science/article/abs/pii/S1097276523005646
  15. Dec 2022
  16. www.sciencedirect.com www.sciencedirect.com
    POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells
    2
    1. scibot 01 Dec 2022
      RRID: AB_185520

      DOI: 10.1016/j.molcel.2022.11.008

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    2. scibot 01 Dec 2022
      RRID:AB_185520

      DOI: 10.1016/j.molcel.2022.11.008

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    sciencedirect.com/science/article/pii/S109727652201070X
  17. Oct 2021
  18. www.sciencedirect.com www.sciencedirect.com
    Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair
    1
    1. scibot 16 Oct 2021
      RRID:AB_185520

      DOI: 10.1016/j.neuron.2021.09.040

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    sciencedirect.com/science/article/pii/S0896627321007133
  19. www.sciencedirect.com www.sciencedirect.com
    Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males
    1
    1. scibot 13 Oct 2021
      RRID:AB_185520

      DOI: 10.1016/j.celrep.2021.109813

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    sciencedirect.com/science/article/pii/S2211124721012778
  20. Sep 2021
  21. www.sciencedirect.com www.sciencedirect.com
    REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
    1
    1. scibot 11 Sep 2021
      RRID:AB_185520

      DOI: 10.1016/j.molcel.2021.08.016

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    sciencedirect.com/science/article/pii/S1097276521006833
  22. Aug 2021
  23. academic.oup.com academic.oup.com
    Basal Autophagy Deficiency Causes Thyroid Follicular Epithelial Cell Death in Mice
    1
    1. scibot 14 Aug 2021
      RRID:AB_185520

      DOI: 10.1210/en.2019-00312

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    academic.oup.com/endo/article/160/9/2085/5532589
  24. www.sciencedirect.com www.sciencedirect.com
    BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and Replication
    1
    1. scibot 09 Aug 2021
      RRID:AB_185520

      DOI: 10.1016/j.celrep.2018.10.079

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    sciencedirect.com/science/article/pii/S2211124718316838
  25. www.sciencedirect.com www.sciencedirect.com
    Exocyst protein subnetworks integrate Hippo and mTOR signaling to promote virus detection and cancer
    1
    1. scibot 05 Aug 2021
      RRID:AB_185520

      DOI: 10.1016/j.celrep.2021.109491

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    sciencedirect.com/science/article/pii/S2211124721009189
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 05 Aug 2021
      RRID:AB_185520

      DOI: 10.1016/j.stem.2019.02.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC6458988/
  27. Jul 2021
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 30 Jul 2021
      RRID:AB_185520

      DOI: 10.1016/j.molcel.2018.08.042

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    ncbi.nlm.nih.gov/pmc/articles/PMC6242708/
  29. Apr 2021
  30. www.sciencedirect.com www.sciencedirect.com
    Functional interrogation of DNA damage response variants with base editing screens
    1
    1. scibot 12 Apr 2021
      RRID:AB_185520

      DOI: 10.1016/j.cell.2021.01.041

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    sciencedirect.com/science/article/pii/S0092867421000842
  31. Feb 2021
  32. www.sciencedirect.com www.sciencedirect.com
    A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability
    1
    1. scibot 24 Feb 2021
      RRID:AB_185520

      DOI: 10.1016/j.celrep.2020.01.020

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    sciencedirect.com/science/article/pii/S2211124720300292
  33. Dec 2020
  34. www.sciencedirect.com www.sciencedirect.com
    RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions
    1
    1. scibot 23 Dec 2020
      RRID:AB_185520

      DOI: 10.1016/j.celrep.2020.108546

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    sciencedirect.com/science/article/pii/S2211124720315357
  35. www.sciencedirect.com www.sciencedirect.com
    Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
    1
    1. scibot 17 Dec 2020
      RRID:AB_185520

      DOI: 10.1016/j.molcel.2020.12.006

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    sciencedirect.com/science/article/pii/S1097276520308984
  36. www.sciencedirect.com www.sciencedirect.com
    DNA Damage Baseline Predicts Resilience to Space Radiation and Radiotherapy
    1
    1. scibot 07 Dec 2020
      RRID:AB_185520

      DOI: 10.1016/j.celrep.2020.108434

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    sciencedirect.com/science/article/pii/S2211124720314236
  37. Sep 2020
  38. www.sciencedirect.com www.sciencedirect.com
    SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells
    1
    1. scibot 25 Sep 2020
      RRID:AB_185520

      DOI: 10.1016/j.celrep.2020.108184

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    sciencedirect.com/science/article/pii/S2211124720311736
  39. academic.oup.com academic.oup.com
    Hormonal Regulation of Autophagy in Thyroid PCCL3 Cells and the Thyroids of Male Mice
    1
    1. scibot 16 Sep 2020
      RRID:AB_185520

      DOI: 10.1210/jendso/bvaa054

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    academic.oup.com/jes/article/4/7/bvaa054/5837712
  40. www.sciencedirect.com www.sciencedirect.com
    A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability
    1
    1. scibot 05 Sep 2020
      RRID:AB_185520

      DOI: 10.1016/j.celrep.2020.01.020

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    sciencedirect.com/science/article/pii/S2211124720300292
  41. www.sciencedirect.com www.sciencedirect.com
    Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells
    1
    1. scibot 05 Sep 2020
      RRID:AB_185520

      DOI: 10.1016/j.celrep.2020.03.029

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    sciencedirect.com/science/article/pii/S2211124720303430
  42. May 2020
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-cell aging markers have heterogeneous distribution and are induced by insulin resistance
    1
    1. nPOD_Curator 15 May 2020
      Immunostaining and morphometric evaluation Paraffin sections were incubated overnight with primary antibody (Key Resources Table). For each antibody, sections were stained and imaged in parallel such that the staining intensity reflects the protein expression. For quantification, images were captured systematically covering the whole section in confocal mode on a Zeiss LSM 710 microscope. Every cluster of insulin-stained cells (3–7 cells) or islet (8 or more cells)/section was evaluated; sections were coded and read blindly. For each age, 3–4 animals were evaluated for each staining. For human samples, sections from one block from the body of the pancreas from donors as listed in Key Resources Table.

      Immunostaining and morphometric evaluation

      (includes p53BP1 and IGF1r)

      obiwan:Method RRID:AB_731540 RRID:AB_185520 PMID:28380379
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    ncbi.nlm.nih.gov/pmc/articles/PMC5471618/
  44. Jan 2020
  45. www.sciencedirect.com www.sciencedirect.com
    IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_185520

      DOI: 10.1016/j.molcel.2019.05.036

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    sciencedirect.com/science/article/pii/S1097276519304332
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint
    1
    1. scibot 13 Jan 2020
      RRID:AB_185520

      DOI: 10.7554/eLife.44353

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC6561707/
  47. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_185520

      DOI: 10.1016/j.cmet.2019.03.004

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    sciencedirect.com/science/article/pii/S1550413119301329
  48. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_185520

      DOI: 10.1016/j.stem.2019.02.019

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    sciencedirect.com/science/article/pii/S1934590919300712
  49. Nov 2018
  50. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 05 Nov 2018
      RRID:AB_185520

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    sciencedirect.com/science/article/pii/S1097276518307020
  51. www.sciencedirect.com www.sciencedirect.com
    Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair
    1
    1. scibot 05 Nov 2018
      RRID:AB_185520

      Curator: @Jmenke

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      RRID:AB_185520 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867418311176