23 Matching Annotations
  1. Jun 2024
  2. www.cell.com www.cell.com
    CHK1 inhibitor SRA737 is active in PARP inhibitor resistant and CCNE1 amplified ovarian cancer
    1
    1. scibot 29 Jun 2024
      RRID:AB_185548

      DOI: 10.1016/j.isci.2024.109978

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    cell.com/iscience/abstract/S2589-0042(24)01200-8
  3. Mar 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RTF2 controls replication repriming and ribonucleotide excision at the replisome
    1
    1. scibot 06 Mar 2024
      RRID:AB_185548

      DOI: 10.1038/s41467-024-45947-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10908796/
  5. Feb 2024
  6. aacrjournals.org aacrjournals.org
    A Phase 1 Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-Dose Gemcitabine in Metastatic Pancreatic Adenocarcinoma Patients
    1
    1. scibot 24 Feb 2024
      RRID:AB_185548

      DOI: 10.1158/1078-0432.CCR-23-2005

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    aacrjournals.org/clincancerres/article/29/24/5047/731678/A-Phase-I-Expansion-Cohort-Study-Evaluating-the
  7. www.sciencedirect.com www.sciencedirect.com
    SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
    1
    1. scibot 02 Feb 2024
      RRID:AB_185548

      DOI: 10.1016/j.cell.2024.01.008

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    sciencedirect.com/science/article/pii/S0092867424000102
  8. Dec 2023
  9. 52.53.155.43 52.53.155.43
    ccr-23-2005-html.html
    1
    1. scibot 01 Dec 2023
      RRID:AB_185548

      DOI: 10.1158/1078-0432.ccr-23-2005

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    52.53.155.43/8373d350712629607ae5ff64c6434e7646ebbbe9/ccr-23-2005-html.html
  10. Nov 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Replicative stress in gastroesophageal premalignancy is associated with chromosomal instability and sensitivity to DNA damage response inhibitors
    1
    1. scibot 04 Nov 2023
      RRID:AB_185548

      DOI: 10.1016/j.isci.2023.108169

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    sciencedirect.com/science/article/pii/S2589004223022460
  12. Sep 2023
  13. www.sciencedirect.com www.sciencedirect.com
    The interplay of TARG1 and PARG protects against genomic instability
    1
    1. scibot 12 Sep 2023
      RRID:AB_185548

      DOI: 10.1016/j.celrep.2023.113113

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    sciencedirect.com/science/article/pii/S2211124723011245
  14. Nov 2022
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Replication stress defines distinct molecular subtypes across cancers
    1
    1. scibot 19 Nov 2022
      AB_185548

      DOI: 10.1158/2767-9764.crc-22-0168

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    ncbi.nlm.nih.gov/pmc/articles/PMC9648410/
  16. www.sciencedirect.com www.sciencedirect.com
    Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2
    1
    1. scibot 16 Nov 2022
      RRID:AB_185548

      DOI: 10.1016/j.celrep.2022.111670

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    sciencedirect.com/science/article/pii/S2211124722015443
  17. Aug 2021
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation
    1
    1. scibot 14 Aug 2021
      RRID:AB_185548

      DOI: 10.1093/nar/gkz076

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    ncbi.nlm.nih.gov/pmc/articles/PMC6486545/
  19. Jun 2021
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability
    1
    1. scibot 18 Jun 2021
      RRID:AB_185548

      DOI: 10.1016/j.isci.2021.102534

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    ncbi.nlm.nih.gov/pmc/articles/PMC8184511/
  21. Apr 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Functional interrogation of DNA damage response variants with base editing screens
    1
    1. scibot 12 Apr 2021
      RRID:AB_185548

      DOI: 10.1016/j.cell.2021.01.041

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    sciencedirect.com/science/article/pii/S0092867421000842
  23. Mar 2021
  24. www.sciencedirect.com www.sciencedirect.com
    MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity
    1
    1. scibot 03 Mar 2021
      RRID:AB_185548

      DOI: 10.1016/j.celrep.2021.108808

      Resource: (Bethyl Cat# A300-244A, RRID:AB_185548)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:AB_185548
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    sciencedirect.com/science/article/pii/S2211124721001224
  25. Jan 2021
  26. www.sciencedirect.com www.sciencedirect.com
    A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans
    1
    1. scibot 05 Jan 2021
      AB_185548

      DOI: 10.1016/j.celrep.2020.108559

      Resource: (Bethyl Cat# A300-244A, RRID:AB_185548)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:AB_185548
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    sciencedirect.com/science/article/pii/S2211124720315485
  27. Jan 2020
  28. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:AB_185548

      DOI: 10.1016/j.celrep.2019.01.013

      Resource: (Bethyl Cat# A300-244A, RRID:AB_185548)

      Curator: @ethanbadger

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      RRID:AB_185548 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S221112471930021X
  29. www.sciencedirect.com www.sciencedirect.com
    Ca2+-Stimulated AMPK-Dependent Phosphorylation of Exo1 Protects Stressed Replication Forks from Aberrant Resection
    1
    1. scibot 13 Jan 2020
      RRID:AB_185548

      DOI: 10.1016/j.molcel.2019.04.003

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      Curator: @ethanbadger

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      RRID:AB_185548 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519302734
  30. www.sciencedirect.com www.sciencedirect.com
    DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors
    1
    1. scibot 13 Jan 2020
      RRID:AB_185548

      DOI: 10.1016/j.ccell.2019.02.004

      Resource: (Bethyl Cat# A300-244A, RRID:AB_185548)

      Curator: @ethanbadger

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      RRID:AB_185548 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610819300996
  31. academic.oup.com academic.oup.com
    Untitled document
    1
    1. scibot 12 Jan 2020
      RRID:AB_185548

      DOI: 10.1093/nar/gkz076

      Resource: (Bethyl Cat# A300-244A, RRID:AB_185548)

      Curator: @evieth

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      RRID:AB_185548 RRIDCUR:Validated
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkz076/5364135
  32. Nov 2018
  33. www.sciencedirect.com www.sciencedirect.com
    Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase
    1
    1. scibot 05 Nov 2018
      RRID:AB_185548

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      (Bethyl Cat# A300-244A, RRID:AB_185548)

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    sciencedirect.com/science/article/pii/S1097276518305586
  34. www.sciencedirect.com www.sciencedirect.com
    The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations
    1
    1. scibot 05 Nov 2018
      RRID:AB_185548

      Curator: @Jmenke

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      (Bethyl Cat# A300-244A, RRID:AB_185548)

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      RRID:AB_185548 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517310080
  35. www.sciencedirect.com www.sciencedirect.com
    Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers
    1
    1. scibot 05 Nov 2018
      RRID:AB_185548

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      (Bethyl Cat# A300-244A, RRID:AB_185548)

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      RRID:AB_185548
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    sciencedirect.com/science/article/pii/S1097276517307141
  36. Nov 2017
  37. www.sciencedirect.com www.sciencedirect.com
    RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination
    1
    1. scibot 08 Nov 2017
      AB_185548

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      (Bethyl Cat# A300-244A, RRID:AB_185548)

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    sciencedirect.com/science/article/pii/S1097276517302782
  38. www.sciencedirect.com www.sciencedirect.com
    RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health
    1
    1. scibot 08 Nov 2017
      AB_185548

      Curator: @Zeljana_Babic

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      (Bethyl Cat# A300-244A, RRID:AB_185548)

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      RRID:AB_185548 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517302770