29 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    A new neuroprotective candidate TJ1 targeting amyloidogenesis in 5xFAD Alzheimer’s disease mice
    1
    1. scibot 19 Jul 2024
      RRID:AB_1903900

      DOI: 10.1016/j.intimp.2024.112653

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    sciencedirect.com/science/article/pii/S1567576924011743
  3. Oct 2023
  4. www.science.org www.science.org
    Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance
    1
    1. scibot 17 Oct 2023
      AB_1903900

      DOI: 10.1126/sciadv.abo3610

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    science.org/doi/10.1126/sciadv.abo3610
  5. Jun 2023
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model
    1
    1. scibot 03 Jun 2023
      RRID:AB_190390

      DOI: 10.1016/j.isci.2023.106375

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    ncbi.nlm.nih.gov/pmc/articles/PMC10074152/
  7. May 2023
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptides
    1
    1. scibot 06 May 2023
      AB_1903900

      DOI: 10.1186/s13024-023-00611-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10161466/
  9. Nov 2022
  10. www.researchsquare.com www.researchsquare.com
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    1. scibot 11 Nov 2022
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      DOI: 10.21203/rs.3.rs-658360/v1

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    researchsquare.com/article/rs-2787982/v1
  11. Oct 2022
  12. alzres.biomedcentral.com alzres.biomedcentral.com
    Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ
    1
    1. scibot 25 Oct 2022
      RRID:AB_1903900

      DOI: 10.1186/s13195-022-01096-3

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    alzres.biomedcentral.com/articles/10.1186/s13195-022-01096-3
  13. Sep 2022
  14. www.sciencedirect.com www.sciencedirect.com
    Error-prone protein synthesis recapitulates early symptoms of Alzheimer disease in aging mice
    1
    1. scibot 28 Sep 2022
      RRID:AB_1903900

      DOI: 10.1016/j.celrep.2022.111433

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    sciencedirect.com/science/article/pii/S2211124722012748
  15. Aug 2022
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance
    2
    1. scibot 13 Aug 2022
      AB_1903900

      DOI: 10.1126/sciadv.abo3610

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    2. scibot 13 Aug 2022
      AB_1903900

      DOI: 10.1126/sciadv.abo3610

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    ncbi.nlm.nih.gov/pmc/articles/PMC9299535/
  17. Jul 2022
  18. www.sciencedirect.com www.sciencedirect.com
    Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice
    1
    1. scibot 13 Jul 2022
      RRID:AB_190390

      DOI: 10.1016/j.celrep.2022.111062

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    sciencedirect.com/science/article/pii/S2211124722008609
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1
    1
    1. scibot 06 Jul 2022
      AB_1903900

      DOI: 10.1126/sciadv.abo1286

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    ncbi.nlm.nih.gov/pmc/articles/PMC9205595/
  20. Aug 2021
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology
    1
    1. scibot 25 Aug 2021
      RRID:AB_1903900

      DOI: 10.1016/j.isci.2021.102942

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    ncbi.nlm.nih.gov/pmc/articles/PMC8369003/
  22. May 2021
  23. www.sciencedirect.com www.sciencedirect.com
    Thymoquinone administration ameliorates Alzheimer's disease-like phenotype by promoting cell survival in the hippocampus of amyloid beta1-42 infused rat model
    1
    1. scibot 09 May 2021
      AB_1903900

      DOI: 10.1016/j.phymed.2020.153324

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    sciencedirect.com/science/article/pii/S0944711320301562
  24. Feb 2021
  25. portlandpress.com portlandpress.com
    The cellular expression and proteolytic processing of the amyloid precursor protein is independent of TDP-43
    1
    1. scibot 25 Feb 2021
      AB_1903900

      DOI: 10.1042/BSR20200435

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    portlandpress.com/bioscirep/article/40/4/BSR20200435/222674/The-cellular-expression-and-proteolytic-processing
  26. Sep 2020
  27. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sleep deprivation regulates availability of PrPC and Aβ peptides which can impair interaction between PrPC and laminin and neuronal plasticity
    1
    1. scibot 17 Sep 2020
      RRID:AB_1903900

      DOI: 10.1111/jnc.14960

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14960
  28. link.springer.com link.springer.com
    Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer’s disease
    1
    1. scibot 06 Sep 2020
      AB_1903900

      DOI: 10.1186/s40478-020-01013-5

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    link.springer.com/article/10.1186/s40478-020-01013-5
  29. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 04 Sep 2020
      β‐site APP cleaving enzyme 1 (BACE1) rabbit mAb

      DOI: 10.1111/bph.14963

      Resource: (Cell Signaling Technology Cat# 5606, RRID:AB_1903900)

      Curator: @Naa003

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      Curator comments: BACE (D10E5) Rabbit mAb antibody Cell Signaling Technology Cat# 5606

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14963
  30. Jan 2020
  31. jcb.rupress.org jcb.rupress.org
    A cellular complex of BACE1 and γ-secretase sequentially generates Aβ from its full-length precursor
    1
    1. scibot 13 Jan 2020
      RRID:AB_1903900

      DOI: 10.1083/jcb.201806205

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      RRID:AB_1903900 RRIDCUR:Validated
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    jcb.rupress.org/content/218/2/644
  32. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Label‐free distribution of anti‐amyloid D‐AIP in Drosophila melanogaster: prevention of Aβ42‐induced toxicity without side effects in transgenic flies
    1
    1. scibot 13 Jan 2020
      RRID:AB_1903900

      DOI: 10.1111/jnc.14720

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14720
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Activation of peroxisome proliferator‐activated receptor delta suppresses BACE1 expression by up‐regulating SOCS1 in a JAK2/STAT1‐dependent manner
    1
    1. scibot 13 Jan 2020
      RRID:AB_1903900

      DOI: 10.1111/jnc.14715

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14715
  34. www.sciencedirect.com www.sciencedirect.com
    Loss of Ataxin-1 Potentiates Alzheimer’s Pathogenesis by Elevating Cerebral BACE1 Transcription
    1
    1. scibot 13 Jan 2020
      RRID:AB_1903900

      DOI: 10.1016/j.cell.2019.07.043

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S0092867419308438
  35. www.jneurosci.org www.jneurosci.org
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_1903900

      DOI: 10.1523/JNEUROSCI.1280-17.2018

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    jneurosci.org/content/38/18/4288
  36. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 12 Jan 2020
      RRID:AB_1903900

      DOI: 10.1016/j.celrep.2019.01.009

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2211124719300178
  37. Nov 2018
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 05 Nov 2018
      AB_1903900

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    ncbi.nlm.nih.gov/pmc/articles/PMC6154927/
  39. actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com
    Untitled document
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    1. scibot 05 Nov 2018
      AB_1903900

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    actaneurocomms.biomedcentral.com/articles/10.1186/s40478-018-0603-4
  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The non‐peptidic δ‐opioid receptor agonist Tan‐67 mediates neuroprotection post‐ischemically and is associated with altered amyloid precursor protein expression, maturation and processing in mice
    1
    1. scibot 05 Nov 2018
      RRID:AB_1903900

      Curator: @evieth

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14265/full
  41. Nov 2017
  42. www.jneurosci.org www.jneurosci.org
    Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model
    1
    1. scibot 08 Nov 2017
      AB_1903900

      Curator: @chewbeccax

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    jneurosci.org/content/37/20/5099
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of Cathepsin B and L Leads to Lysosomal Dysfunction, NPC-Like Cholesterol Sequestration and Accumulation of the Key Alzheimer's Proteins
    2
    1. scibot 08 Nov 2017
      AB_1903900

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    2. scibot 08 Nov 2017
      AB_1903900

      Curator: @gabimpine

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    ncbi.nlm.nih.gov/pmc/articles/PMC5130271/