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  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CerS2 is a druggable target in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13678703/
  3. Sep 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PLK1 inhibition by volasertib suppresses key transcriptional regulators underlying fibroblast activation and pulmonary fibrosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13531454/
  5. Jul 2026
  6. link.springer.com link.springer.com
    Supra-additive neuroprotective effects of berberine–metformin combination in diabetic encephalopathy: Chou–Talalay synergy quantification, AMPK–Nrf2 axis modulation, and pharmacokinetic verification
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    link.springer.com/article/10.1007/s11011-026-01910-z
  7. May 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Triptolide enhances anti-cancer activities of irinotecan in human colon cancer HT-29 cells in vitro and HT-29 cell xenograft tumor model in nude mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC13201951/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13130659/
  10. Apr 2026
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chronic psychological stress disrupts liver homeostasis by dysregulating oxidative phosphorylation via the PI3K/AKT/FoxO3a axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13068581/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Proteomic profiling of extracellular fluids to identify secreted proteins from muscle and fat tissues
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    pmc.ncbi.nlm.nih.gov/articles/PMC13054959/
  13. Mar 2026
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    A preclinical candidate of cyclophilin D inhibition improves alcohol-associated liver injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC13006403/
  15. Feb 2026
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Microbial Bile Acid Metabolite 3-oxo-LCA Inhibits Colorectal Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12871761/
  17. Dec 2025
  18. 54.241.53.176 54.241.53.176
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  19. Nov 2025
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    Bicyclol improves cognition deficits and inhibits oxidative stress-induced neuronal cell apoptosis in alzheimer’s disease via Nrf2/HO-1 pathway
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    link.springer.com/article/10.1007/s11011-025-01738-z
  21. Sep 2025
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    FLT3L-based drug conjugate effectively targets chemoresistant leukemia stem cells in acute myeloid leukemia
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    Neuroprotective effects of Yangming-Kaixin-Yizhi formula in Alzheimer’s disease: dual regulation of PI3K/Akt and p38 MAPK signaling via network pharmacology and experimental approaches
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  24. Aug 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    De novo pyrimidine biosynthesis inhibition synergizes with BCL-XL targeting in pancreatic cancer
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  26. Jul 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Uric Acid Causes Pancreatic β Cell Death and Dysfunction via Modulating CHOP-Mediated Endoplasmic Reticulum Stress Pathways
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    Paclitaxel-induced mitotic arrest results in a convergence of apoptotic dependencies that can be safely exploited by BCL-XL degradation to overcome cancer chemoresistance
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    biorxiv.org/content/10.1101/2025.06.24.661170v1
  29. Jun 2025
  30. 52.53.155.43 52.53.155.43
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  31. May 2025
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    AARS2 ameliorates myocardial ischemia via fine-tuning PKM2-mediated metabolism
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  33. Apr 2025
  34. www.nature.com www.nature.com
    Jorunnamycin A induces apoptosis in pancreatic ductal adenocarcinoma cells, spheroids, and patient-derived organoids by modulating KRAS-mediated survival pathways
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  37. Nov 2024
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    Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer
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  39. Aug 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells
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    Chinese medicine Linggui Zhugan formula protects against diabetic kidney disease in close association with inhibition of proteinase 3-mediated podocyte apoptosis in mice
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  42. Jun 2024
  43. www.cell.com www.cell.com
    Oxygen tension-dependent variability in the cancer cell kinome impacts signaling pathways and response to targeted therapies
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  44. May 2024
  45. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Excessive intragastric alcohol administration exacerbates hepatic encephalopathy and provokes neuronal cell death in male rats with chronic liver disease
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  46. Feb 2024
  47. www.cell.com www.cell.com
    Methionine secreted by tumor-associated pericytes supports cancer stem cells in clear cell renal carcinoma
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    Inhibition of mGluR5/PI3K-AKT Pathway Alleviates Alzheimer’s Disease-Like Pathology Through the Activation of Autophagy in 5XFAD Mice
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  50. www.mdpi.com www.mdpi.com
    Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress
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  51. Jan 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    circGlis3 promotes β-cell dysfunction by inhibiting hnRNPF nuclear translocation and encoding Glis3-348aa protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC10788204/
  53. Nov 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Fucoxanthin ameliorates traumatic brain injury by suppressing the blood brain barrier disruption
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  55. Mar 2023
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    A high-sucrose diet exacerbates the left ventricular phenotype in a high fat-fed streptozotocin rat model of diabetic cardiomyopathy
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    Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer
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  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Echinocystic acid alleviated hypoxic-ischemic brain damage in neonatal mice by activating the PI3K/Akt/Nrf2 signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC9947717/
  59. Jan 2023
  60. www.sciencedirect.com www.sciencedirect.com
    Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues
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  61. Dec 2022
  62. www.mdpi.com www.mdpi.com
    Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines
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    mdpi.com/2072-6643/14/24/5265
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    Selaginella tamariscina Inhibits Glutamate-Induced Autophagic Cell Death by Activating the PI3K/AKT/mTOR Signaling Pathways
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteomic-Based Approach Reveals the Involvement of Apolipoprotein A-I in Related Phenotypes of Autism Spectrum Disorder in the BTBR Mouse Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC9737945/
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    The Neuroprotective Effects of Arecae Pericarpium against Glutamate-Induced HT22 Cell Cytotoxicity
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    mdpi.com/1467-3045/44/12/402
  66. Jun 2022
  67. academic.oup.com academic.oup.com
    Deficiency of C1QL1 reduced murine ovarian follicle reserve through intraovarian and endocrine control
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    academic.oup.com/endo/article/163/6/bqac048/6569208
  68. May 2022
  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta-TC-6 cells via the generation of intracellular reactive oxygen species and mitochondrial superoxide
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    onlinelibrary.wiley.com/doi/10.1002/jbt.23099
  70. Mar 2022
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    Urolithin A alleviates blood-brain barrier disruption and... : Neural Regeneration Research
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  72. Jan 2022
  73. www.sciencedirect.com www.sciencedirect.com
    Mechanosensitive Channel Piezo1 Induces Cell Apoptosis in Pancreatic Cancer by Ultrasound with Microbubbles
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  74. Feb 2021
  75. academic.oup.com academic.oup.com
    Activation of ovarian taste receptors inhibits progesterone production potentially via NO/cGMP and apoptotic signaling
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    academic.oup.com/endo/article/162/3/bqaa240/6052298
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    LncRNA-Malat1 is involved in lipotoxicity-induced β-cell dysfunction and the therapeutic effect of exendin-4 via Ptbp1
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    academic.oup.com/endo/article/161/7/bqaa065/5824261
  77. Sep 2020
  78. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  79. www.nature.com www.nature.com
    Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling
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    nature.com/articles/s41419-020-02805-2
  80. Jan 2020
  81. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Lactoferrin protects against iron dysregulation, oxidative stress, and apoptosis in MPTP‐induced Parkinson's disease in mice
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14857
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    Andrographolide alleviates parkinsonism in MPTP‐PD mice via targeting DRP1‐mediated mitochondrial fission
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  84. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Diosmetin induces apoptosis and enhances the chemotherapeutic efficacy of paclitaxel in non‐small cell lung cancer cells via Nrf2 inhibition
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  85. Nov 2018
  86. www.sciencedirect.com www.sciencedirect.com
    Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM
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    sciencedirect.com/science/article/pii/S0896627318307839
  87. academic.oup.com academic.oup.com
    A Sustained Activation of Pancreatic NMDARs Is a Novel Factor of β-Cell Apoptosis and Dysfunction
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  88. Nov 2017
  89. www.jneurosci.org www.jneurosci.org
    TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway
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    jneurosci.org/content/37/7/1772
  90. www.sciencedirect.com www.sciencedirect.com
    Interleukin-17A mediates cardiomyocyte apoptosis through Stat3-iNOS pathway
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    sciencedirect.com/science/article/pii/S016748891630218X