44 Matching Annotations
  1. Last 7 days
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    Neuroprotective effects of Yangming-Kaixin-Yizhi formula in Alzheimer’s disease: dual regulation of PI3K/Akt and p38 MAPK signaling via network pharmacology and experimental approaches
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    link.springer.com/article/10.1007/s11011-025-01688-6
  3. Aug 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    De novo pyrimidine biosynthesis inhibition synergizes with BCL-XL targeting in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12311037/
  5. Jul 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Uric Acid Causes Pancreatic β Cell Death and Dysfunction via Modulating CHOP-Mediated Endoplasmic Reticulum Stress Pathways
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    pmc.ncbi.nlm.nih.gov/articles/PMC12293447/
  7. www.biorxiv.org www.biorxiv.org
    Paclitaxel-induced mitotic arrest results in a convergence of apoptotic dependencies that can be safely exploited by BCL-XL degradation to overcome cancer chemoresistance
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    biorxiv.org/content/10.1101/2025.06.24.661170v1
  8. Jun 2025
  9. 52.53.155.43 52.53.155.43
    PDF-html.html
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  10. May 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AARS2 ameliorates myocardial ischemia via fine-tuning PKM2-mediated metabolism
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    pmc.ncbi.nlm.nih.gov/articles/PMC12080999/
  12. Apr 2025
  13. www.nature.com www.nature.com
    Jorunnamycin A induces apoptosis in pancreatic ductal adenocarcinoma cells, spheroids, and patient-derived organoids by modulating KRAS-mediated survival pathways
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    nature.com/articles/s41598-025-95766-5
  14. Feb 2025
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  16. Nov 2024
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11532783/
  18. Aug 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
  20. www.sciencedirect.com www.sciencedirect.com
    Chinese medicine Linggui Zhugan formula protects against diabetic kidney disease in close association with inhibition of proteinase 3-mediated podocyte apoptosis in mice
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    sciencedirect.com/science/article/pii/S0378874124009498
  21. Jun 2024
  22. www.cell.com www.cell.com
    Oxygen tension-dependent variability in the cancer cell kinome impacts signaling pathways and response to targeted therapies
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    cell.com/iscience/abstract/S2589-0042(24)01293-8
  23. May 2024
  24. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Excessive intragastric alcohol administration exacerbates hepatic encephalopathy and provokes neuronal cell death in male rats with chronic liver disease
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    onlinelibrary.wiley.com/doi/10.1002/jnr.25337
  25. Feb 2024
  26. www.cell.com www.cell.com
    Methionine secreted by tumor-associated pericytes supports cancer stem cells in clear cell renal carcinoma
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    cell.com/cell-metabolism/abstract/S1550-4131(24)00018-4
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    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16283
  28. content.iospress.com content.iospress.com
    Inhibition of mGluR5/PI3K-AKT Pathway Alleviates Alzheimer’s Disease-Like Pathology Through the Activation of Autophagy in 5XFAD Mice
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    content.iospress.com/articles/journal-of-alzheimers-disease/jad221058
  29. www.mdpi.com www.mdpi.com
    Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress
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    mdpi.com/1467-3045/45/12/620
  30. Jan 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    circGlis3 promotes β-cell dysfunction by inhibiting hnRNPF nuclear translocation and encoding Glis3-348aa protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC10788204/
  32. Nov 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Fucoxanthin ameliorates traumatic brain injury by suppressing the blood brain barrier disruption
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    sciencedirect.com/science/article/pii/S2589004223023477
  34. Mar 2023
  35. 52.53.155.43 52.53.155.43
    A high-sucrose diet exacerbates the left ventricular phenotype in a high fat-fed streptozotocin rat model of diabetic cardiomyopathy
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    52.53.155.43/a2856e34c76df1f90e78f95405a1557ff7dcdfbe/ajpheart.00390.2022-html.html
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    Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer
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    sciencedirect.com/science/article/pii/S1535610823000326
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Echinocystic acid alleviated hypoxic-ischemic brain damage in neonatal mice by activating the PI3K/Akt/Nrf2 signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC9947717/
  38. Jan 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues
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    sciencedirect.com/science/article/pii/S1550413122005770
  40. Dec 2022
  41. www.mdpi.com www.mdpi.com
    Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines
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    mdpi.com/2072-6643/14/24/5265
  42. 52.53.155.43 52.53.155.43
    Selaginella tamariscina Inhibits Glutamate-Induced Autophagic Cell Death by Activating the PI3K/AKT/mTOR Signaling Pathways
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    52.53.155.43/eb3e7bd6fec17f8c00ac186e434aef30e82c163b/ijms-23-11445-html.html
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteomic-Based Approach Reveals the Involvement of Apolipoprotein A-I in Related Phenotypes of Autism Spectrum Disorder in the BTBR Mouse Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC9737945/
  44. www.mdpi.com www.mdpi.com
    The Neuroprotective Effects of Arecae Pericarpium against Glutamate-Induced HT22 Cell Cytotoxicity
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    mdpi.com/1467-3045/44/12/402
  45. Jun 2022
  46. academic.oup.com academic.oup.com
    Deficiency of C1QL1 reduced murine ovarian follicle reserve through intraovarian and endocrine control
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    academic.oup.com/endo/article/163/6/bqac048/6569208
  47. May 2022
  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta-TC-6 cells via the generation of intracellular reactive oxygen species and mitochondrial superoxide
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    onlinelibrary.wiley.com/doi/10.1002/jbt.23099
  49. Mar 2022
  50. journals.lww.com journals.lww.com
    Urolithin A alleviates blood-brain barrier disruption and... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2022/17090/Urolithin_A_alleviates_blood_brain_barrier.32.aspx
  51. Jan 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Mechanosensitive Channel Piezo1 Induces Cell Apoptosis in Pancreatic Cancer by Ultrasound with Microbubbles
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    sciencedirect.com/science/article/pii/S2589004222000037
  53. Feb 2021
  54. academic.oup.com academic.oup.com
    Activation of ovarian taste receptors inhibits progesterone production potentially via NO/cGMP and apoptotic signaling
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    academic.oup.com/endo/article/162/3/bqaa240/6052298
  55. academic.oup.com academic.oup.com
    LncRNA-Malat1 is involved in lipotoxicity-induced β-cell dysfunction and the therapeutic effect of exendin-4 via Ptbp1
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    academic.oup.com/endo/article/161/7/bqaa065/5824261
  56. Sep 2020
  57. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14998
  58. www.nature.com www.nature.com
    Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling
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    nature.com/articles/s41419-020-02805-2
  59. Jan 2020
  60. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Lactoferrin protects against iron dysregulation, oxidative stress, and apoptosis in MPTP‐induced Parkinson's disease in mice
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14857
  61. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Andrographolide alleviates parkinsonism in MPTP‐PD mice via targeting DRP1‐mediated mitochondrial fission
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14823
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6307859/
  63. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Diosmetin induces apoptosis and enhances the chemotherapeutic efficacy of paclitaxel in non‐small cell lung cancer cells via Nrf2 inhibition
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14652
  64. Nov 2018
  65. www.sciencedirect.com www.sciencedirect.com
    Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM
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    sciencedirect.com/science/article/pii/S0896627318307839
  66. academic.oup.com academic.oup.com
    A Sustained Activation of Pancreatic NMDARs Is a Novel Factor of β-Cell Apoptosis and Dysfunction
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    academic.oup.com/endo/article/158/11/3900/4103351
  67. Nov 2017
  68. www.jneurosci.org www.jneurosci.org
    TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway
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    jneurosci.org/content/37/7/1772
  69. www.sciencedirect.com www.sciencedirect.com
    Interleukin-17A mediates cardiomyocyte apoptosis through Stat3-iNOS pathway
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    sciencedirect.com/science/article/pii/S016748891630218X