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The Histone Methyltransferase KMT2D is a Critical Mediator of Lineage Plasticity and Therapeutic Response in Castration Resistant Prostate Cancer

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1. scibot 14 Feb 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-2053
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12900249/
Feb 2026
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HOXC6 overexpression stimulates cell migration and correlates with poor prognosis in head and neck squamous cell carcinoma

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1. scibot 04 Feb 2026
  
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  DOI: 10.1007/s00018-025-06039-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12858702/
Nov 2025
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Deficiency of HMGN2 enhances antibacterial activity of macrophages by promoting H3 histone modification-mediated CD14/iNOS expression

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1. scibot 15 Nov 2025
  
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  DOI: 10.3389/fimmu.2025.1621440
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12611830/
Oct 2025
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PHF19 drives the formation of PRC2 clusters to enhance motility in TNBC cells

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1. scibot 09 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116391
  
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sciencedirect.com/science/article/pii/S2211124725011623
Sep 2025
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Lactate modulates the function of myeloid-derived suppressor cells via Ten-Eleven-Translocation-2-mediated demethylation of glucocorticoid-inducible kinase 1 in lung cancer model

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1. scibot 11 Sep 2025
  
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  DOI: 10.3389/fcell.2025.1565993
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12411531/
www.biorxiv.org www.biorxiv.org

Regulatory Role for Tumor Suppressor REST on Estrogen Receptor (ESR1) Expression and Leiomyoma Pathophysiology

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1. scibot 06 Sep 2025
  
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  DOI: 10.1101/2025.08.29.673140
  
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biorxiv.org/content/10.1101/2025.08.29.673140v1
Jun 2025
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Dynamic decoding of VEGF signaling and coordinated control of multiple phenotypes by the Src-TEM4-YAP pathway

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.cels.2025.101321
  
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sciencedirect.com/science/article/pii/S2405471225001541
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RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis

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1. scibot 11 Jun 2025
  
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  DOI: 10.1158/2159-8290.CD-24-0093
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11611684/
Mar 2025
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Identification of Schizophrenia-Risk Regulatory Variant rs1399178 in the Non-coding Region With Its Impact on NRF1 Binding

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1. scibot 04 Mar 2025
  
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  DOI: 10.1111/cns.70275
  
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onlinelibrary.wiley.com/doi/10.1111/cns.70275
Feb 2025
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Hepatic sphingomyelin phosphodiesterase 3 promotes steatohepatitis by disrupting membrane sphingolipid metabolism

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1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.cmet.2025.01.016
  
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sciencedirect.com/science/article/pii/S1550413125000166
Jun 2024
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Short-term cold exposure induces persistent epigenomic memory in brown fat

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1. scibot 22 Jun 2024
  
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  DOI: 10.1016/j.cmet.2024.05.011
  
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sciencedirect.com/science/article/pii/S1550413124001876
May 2024
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Alarmin S100A8 imparts chemoresistance of esophageal cancer by reprogramming cancer-associated fibroblasts

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1. scibot 23 May 2024
  
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  DOI: 10.1016/j.xcrm.2024.101576
  
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sciencedirect.com/science/article/pii/S2666379124002684
Apr 2024
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Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection

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1. scibot 11 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114007
  
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sciencedirect.com/science/article/pii/S2211124724003358
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ISG12a promotes immunotherapy of HBV-associated hepatocellular carcinoma through blocking TRIM21/AKT/β-Catenin/PD-L1 axis

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1. scibot 10 Apr 2024
  
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  DOI: 10.1016/j.isci.2024.109533
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11000115/
Mar 2024
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Mosaic deletion of claudin-5 reveals rapid non-cell-autonomous consequences of blood-brain barrier leakage

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1. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113911
  
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sciencedirect.com/science/article/pii/S2211124724002390
Feb 2024
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ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion

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1. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113794
  
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sciencedirect.com/science/article/pii/S2211124724001220
Jan 2024
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A Novel Macrolide–Del-1 Axis to Regenerate Bone in Old Age

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1. scibot 23 Jan 2024
  
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  DOI: 10.1016/j.isci.2024.108798
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10797555/
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Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling

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1. scibot 20 Jan 2024
  
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  DOI: 10.1016/j.celrep.2024.113688
  
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sciencedirect.com/science/article/pii/S2211124724000160
Oct 2023
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IκBζ is an essential mediator of immunity to oropharyngeal candidiasis

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1. scibot 01 Oct 2023
  
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  DOI: 10.1016/j.chom.2023.08.016
  
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sciencedirect.com/science/article/abs/pii/S1931312823003414
Mar 2023
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Phosphoenolpyruvate regulates the Th17 transcriptional program and inhibits autoimmunity

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1. scibot 02 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112205
  
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sciencedirect.com/science/article/pii/S2211124723002164
Jan 2023
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SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis

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1. scibot 15 Jan 2023
  
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  DOI: 10.26508/lsa.202201457
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9834662/
Dec 2022
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CEACAM1 is a direct SOX10 target and inhibits melanoma immune infiltration and stemness

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1. scibot 02 Dec 2022
  
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  DOI: 10.1016/j.isci.2022.105524
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9682343/
Nov 2022
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DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability

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1. scibot 23 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111703
  
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sciencedirect.com/science/article/pii/S2211124722015777
Oct 2022
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Prdm14 promotes mouse ESC self-renewal and PGCLC specification through enhancement of Stat3 activity

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1. scibot 27 Oct 2022
  
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  DOI: 10.1016/j.isci.2022.105293
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9589213/
Sep 2022
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Reversible epigenetic alterations regulate class I HLA loss in prostate cancer

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1. scibot 07 Sep 2022
  
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  DOI: 10.1038/s42003-022-03843-6
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9437063/
May 2022
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NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition

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1. scibot 12 May 2022
  
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  DOI: 10.1016/j.molcel.2022.04.015
  
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sciencedirect.com/science/article/pii/S1097276522003264
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Allele-specific aberration of imprinted domain chromosome architecture associates with large offspring syndrome

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1. scibot 10 May 2022
  
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  DOI: 10.1016/j.isci.2022.104269
  
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sciencedirect.com/science/article/pii/S2589004222005399
Mar 2022
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PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade

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1. scibot 30 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110582
  
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sciencedirect.com/science/article/pii/S2211124722003266
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Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells

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1. scibot 26 Mar 2022
  
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  DOI: 10.1016/j.molcel.2022.02.033
  
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sciencedirect.com/science/article/pii/S1097276522002076
Jan 2022
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Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair

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1. scibot 05 Jan 2022
  
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  DOI: 10.1016/j.ccell.2019.04.011
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8717880/
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Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function

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1. scibot 04 Jan 2022
  
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  DOI: 10.1016/j.immuni.2021.12.001
  
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sciencedirect.com/science/article/pii/S1074761321005343
Nov 2021
academic.oup.com academic.oup.com

Transcriptional regulation of LGALS9 by HAND2 and FOXO1 in human endometrial stromal cells in women with regular cycles

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1. scibot 18 Nov 2021
  
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  DOI: 10.1093/molehr/gaab063
  
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academic.oup.com/molehr/article/27/11/gaab063/6377344
Aug 2021
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Untitled document

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1. scibot 09 Aug 2021
  
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  DOI: 10.1523/JNEUROSCI.0702-18.2018
  
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jneurosci.org/content/38/49/10535
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Acetylation of Cytidine in mRNA Promotes Translation Efficiency

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1. scibot 02 Aug 2021
  
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  DOI: 10.1016/j.cell.2018.10.030
  
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sciencedirect.com/science/article/pii/S0092867418313837
Jul 2021
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A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope

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1. scibot 22 Jul 2021
  
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  DOI: 10.1016/j.xcrm.2021.100344
  
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sciencedirect.com/science/article/pii/S2666379121001932
Jun 2021
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SIRT6 transcriptionally regulates fatty acid transport by suppressing PPARγ

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1. scibot 02 Jun 2021
  
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  DOI: 10.1016/j.celrep.2021.109190
  
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May 2021
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Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis

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1. scibot 06 May 2021
  
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  DOI: 10.1016/j.immuni.2020.06.004
  
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sciencedirect.com/science/article/pii/S107476132030234X
Apr 2021
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Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors

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1. scibot 22 Apr 2021
  
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  DOI: 10.1016/j.ccell.2020.10.009
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8455074/
Sep 2020
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Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

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1. scibot 10 Sep 2020
  
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  DOI: 10.1016/j.ccell.2019.12.007
  
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sciencedirect.com/science/article/pii/S153561081930577X
Jan 2020
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Topologically Associated Domains Delineate Susceptibility to Somatic Hypermutation

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.11.039
  
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.02.108
  
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currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com

Untitled document

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  DOI: 10.1002/cpmb.80
  
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currentprotocols.onlinelibrary.wiley.com/doi/full/10.1002/cpmb.80
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Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair

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  DOI: 10.1016/j.ccell.2019.01.020
  
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sciencedirect.com/science/article/pii/S1535610819300546
Nov 2018
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SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis

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Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation

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sciencedirect.com/science/article/pii/S1934590918301085
Nov 2017
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Promoted Interaction of C/EBPα with Demethylated Cxcr3 Gene Promoter Contributes to Neuropathic Pain in Mice

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2. scibot 08 Nov 2017
  
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jneurosci.org/content/37/3/685
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s-Adenosylmethionine Levels Govern Innate Immunity through Distinct Methylation-Dependent Pathways

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sciencedirect.com/science/article/pii/S1550413115003423