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FLT3L-based drug conjugate effectively targets chemoresistant leukemia stem cells in acute myeloid leukemia

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1. scibot 23 Sep 2025
  
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  DOI: 10.1016/j.xcrm.2025.102365
  
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sciencedirect.com/science/article/pii/S2666379125004380
Apr 2025
52.53.155.43 52.53.155.43

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1. scibot 19 Apr 2025
  
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  DOI: 10.1158/1535-7163.mct-24-0756
  
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52.53.155.43/a9bdac937b5d56e963502c7a9aeebc7cca17a770/PDF-html.html
Mar 2025
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The transcription factor MEF2C restrains microglial overactivation by inhibiting kinase CDK2

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.026
  
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sciencedirect.com/science/article/pii/S1074761325000937
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CDKN2A/B homozygous deletion sensitizes IDH-mutant glioma to CDK4/6 inhibition

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1. scibot 25 Jan 2025
  
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  RRID:AB_1904119
  
  DOI: 10.1158/1078-0432.CCR-24-0562
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11250907/
Dec 2024
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Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers

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1. scibot 11 Dec 2024
  
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  RRID:AB_1904119
  
  DOI: 10.1158/2159-8290.CD-23-0866
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11609823/
Nov 2024
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p21 regulates expression of ECM components and promotes pulmonary fibrosis via CDK4 and Rb

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1. scibot 21 Nov 2024
  
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  RRID:AB_1904119
  
  DOI: 10.1038/s44318-024-00246-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11574164/
52.53.155.43 52.53.155.43

can-24-1817-html.html

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1. scibot 14 Nov 2024
  
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  RRID:AB_1904119
  
  DOI: 10.1158/0008-5472.can-24-1817
  
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52.53.155.43/65dca824591f5654591dc592fd6476e0cd35e8bf/can-24-1817-html.html
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PKMYT1 Is a Marker of Treatment Response and a Therapeutic Target for CDK4/6 Inhibitor-Resistance in ER+ Breast Cancer

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1. scibot 04 Oct 2024
  
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  RRID:AB_1904119
  
  DOI: 10.1158/1535-7163.MCT-23-0564
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11443213/
May 2024
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Combined CDK4/6 and ERK1/2 inhibition enhances anti-tumor activity in NF1-associated plexiform neurofibroma

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1. scibot 02 May 2024
  
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  RRID:AB_1904119
  
  DOI: 10.1158/1078-0432.CCR-22-2854
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11060649/
Mar 2024
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CDK-independent role of D-type cyclins in regulating DNA mismatch repair

2
1. scibot 08 Mar 2024
  
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  RRID:AB_1904119
  
  DOI: 10.1016/j.molcel.2024.02.010
  
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2. scibot 08 Mar 2024
  
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  RRID:AB_1904119
  
  DOI: 10.1016/j.molcel.2024.02.010
  
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sciencedirect.com/science/article/pii/S1097276524001291
Jan 2024
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Type 2 cytokine signaling in macrophages protects from cellular senescence and organismal aging

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1. scibot 23 Jan 2024
  
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  DOI: 10.1016/j.immuni.2024.01.001
  
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sciencedirect.com/science/article/pii/S1074761324000268
Aug 2023
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Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function

1
1. scibot 31 Aug 2023
  
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  RRID:AB_1904119
  
  DOI: 10.21203/rs.3.rs-3182731/v1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10441460/
Jun 2023
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Suppression of TREX1 Deficiency-Induced Cellular Senescence and Interferonopathies by Inhibition of DNA Damage Response

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1. scibot 27 Jun 2023
  
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  RRID:AB_1904119
  
  DOI: 10.1016/j.isci.2023.107090
  
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sciencedirect.com/science/article/pii/S2589004223011677
Feb 2023
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Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation

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1. scibot 02 Feb 2023
  
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  DOI: 10.1016/j.celrep.2023.112033
  
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  Curator: @sofiakhan13
  
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sciencedirect.com/science/article/pii/S221112472300044X
Jan 2023
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Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling

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1. scibot 24 Jan 2023
  
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  RRID:AB_1904119
  
  DOI: 10.1016/j.celrep.2023.112031
  
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sciencedirect.com/science/article/pii/S2211124723000426
Sep 2021
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Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor

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1. scibot 14 Sep 2021
  
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  RRID:AB_1904119
  
  DOI: 10.1016/j.ccell.2021.08.009
  
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sciencedirect.com/science/article/pii/S1535610821004499
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Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells

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1. scibot 01 Sep 2021
  
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  RRID:AB_1904119
  
  DOI: 10.1016/j.celrep.2021.109639
  
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sciencedirect.com/science/article/pii/S2211124721010822
Aug 2021
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Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation

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1. scibot 25 Aug 2021
  
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  RRID:AB_1904119
  
  DOI: 10.1016/j.celrep.2021.109565
  
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sciencedirect.com/science/article/pii/S2211124721009992
europepmc.org europepmc.org

Untitled document

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1. scibot 06 Aug 2021
  
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  DOI: 10.7554/eLife.40856
  
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europepmc.org/articles/PMC6292694/
May 2021
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Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer

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1. scibot 07 May 2021
  
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  DOI: 10.1016/j.molcel.2020.04.027
  
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sciencedirect.com/science/article/pii/S1097276520302690
Apr 2021
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Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG

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1. scibot 14 Apr 2021
  
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  RRID:AB_1904119
  
  DOI: 10.1016/j.celrep.2021.108994
  
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sciencedirect.com/science/article/pii/S2211124721003089
Mar 2021
link.springer.com link.springer.com

Boosting CAR T-cell responses in lymphoma by simultaneous targeting of CD40/4-1BB using oncolytic viral gene therapy

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1. scibot 10 Mar 2021
  
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  retinoblastoma protein
  
  DOI: 10.1007/s00262-021-02895-7
  
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link.springer.com/article/10.1007/s00262-021-02895-7
Sep 2020
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Cdk4 and Cdk6 Couple the Cell-Cycle Machinery to Cell Growth via mTORC1

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1. scibot 10 Sep 2020
  
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  RRID:AB_1904119
  
  DOI: 10.1016/j.celrep.2020.03.068
  
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sciencedirect.com/science/article/pii/S2211124720303946
Jan 2020
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Augmenting the therapeutic efficacy of adenosine against pancreatic cancer by switching the Akt/p21-dependent senescence to apoptosis

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1. scibot 13 Jan 2020
  
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  RRID:AB_1904119
  
  DOI: 10.1016/j.ebiom.2019.08.068
  
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sciencedirect.com/science/article/pii/S2352396419305900
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_1904119
  
  DOI: 10.7554/eLife.40856
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6292694/
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_1904119
  
  DOI: 10.1016/j.chembiol.2019.03.012
  
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sciencedirect.com/science/article/pii/S2451945619301084
Nov 2017
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TRIB3 Promotes APL Progression through Stabilization of the Oncoprotein PML-RARα and Inhibition of p53-Mediated Senescence

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1. scibot 08 Nov 2017
  
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  AB_1904119
  
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  RRID:AB_1904119 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610817301617
onlinelibrary.wiley.com onlinelibrary.wiley.com

The antiviral cytokine interferon‐gamma restricts neural stem/progenitor cell proliferation through activation of STAT1 and modulation of retinoblastoma protein phosphorylation

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1. scibot 08 Nov 2017
  
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  AB_1904119
  
  Curator: @chewbeccax
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.23987/full