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Molecular impact of antisense oligonucleotide therapy in C9orf72-associated ALS

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1. scibot 30 Aug 2025
  
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  RRID:AB_1961900
  
  DOI: 10.1016/j.cell.2025.07.045
  
  Resource: (Cosmo Bio Cat# CAC-TIP-PTD-M01, RRID:AB_1961900)
  
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cell.com/cell/abstract/S0092-8674(25)00908-0
May 2025
www.sciencedirect.com www.sciencedirect.com

Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates

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1. scibot 29 May 2025
  
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  RRID:AB_1961900
  
  DOI: 10.1016/j.cell.2025.04.039
  
  Resource: (Cosmo Bio Cat# CAC-TIP-PTD-M01, RRID:AB_1961900)
  
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sciencedirect.com/science/article/pii/S0092867425005094
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Opposing roles of p38α-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy

1
1. scibot 16 Jan 2025
  
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  RRID:AB_1961900
  
  DOI: 10.1016/j.celrep.2024.115205
  
  Resource: (Cosmo Bio Cat# CAC-TIP-PTD-M01, RRID:AB_1961900)
  
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sciencedirect.com/science/article/pii/S2211124724015560
Dec 2024
www.biorxiv.org www.biorxiv.org

Lysine deacetylation inhibition reverses TDP-43 mislocalization and in combination with arimoclomol ameliorates neuromuscular pathology

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1. scibot 21 Dec 2024
  
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  RRID:AB_1961900
  
  DOI: 10.1101/2024.12.15.628528
  
  Resource: (Cosmo Bio Cat# CAC-TIP-PTD-M01, RRID:AB_1961900)
  
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biorxiv.org/content/10.1101/2024.12.15.628528v1
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD

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1. scibot 05 Apr 2024
  
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  RRID:AB_1961900
  
  DOI: 10.1016/j.cell.2024.02.031
  
  Resource: (Cosmo Bio Cat# CAC-TIP-PTD-M01, RRID:AB_1961900)
  
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sciencedirect.com/science/article/pii/S0092867424002344
Aug 2023
www.science.org www.science.org

Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis

1
1. scibot 12 Aug 2023
  
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  RRID:AB_1961900
  
  DOI: 10.1126/sciadv.adf6895
  
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science.org/doi/10.1126/sciadv.adf6895
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis

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1. scibot 10 Aug 2023
  
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  RRID:AB_1961900
  
  DOI: 10.1126/sciadv.adf6895
  
  Resource: (Cosmo Bio Cat# CAC-TIP-PTD-M01, RRID:AB_1961900)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10403219/
Mar 2023
link.springer.com link.springer.com

Disrupted myelin lipid metabolism differentiates frontotemporal dementia caused by GRN and C9orf72 gene mutations

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1. scibot 29 Mar 2023
  
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  AB_1961900
  
  DOI: 10.1186/s40478-023-01544-7
  
  Resource: (Cosmo Bio Cat# CAC-TIP-PTD-M01, RRID:AB_1961900)
  
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link.springer.com/article/10.1186/s40478-023-01544-7
Jan 2022
academic.oup.com academic.oup.com

Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia

1
1. scibot 04 Jan 2022
  
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  AB_1961900
  
  DOI: 10.1093/brain/awab333
  
  Resource: (Cosmo Bio Cat# CAC-TIP-PTD-M01, RRID:AB_1961900)
  
  Curator: @scibot
  
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academic.oup.com/brain/article/144/12/3710/6491324
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis

1
1. scibot 16 Aug 2021
  
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  RRID:AB_1961900
  
  DOI: 10.1186/s13024-021-00470-3
  
  Resource: (Cosmo Bio Cat# CAC-TIP-PTD-M01, RRID:AB_1961900)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8353748/
www.jneurosci.org www.jneurosci.org

Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis

1
1. scibot 13 Aug 2021
  
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  RRID:AB_1961900
  
  DOI: 10.1523/JNEUROSCI.2462-16.2016
  
  Resource: (Cosmo Bio Cat# CAC-TIP-PTD-M01, RRID:AB_1961900)
  
  Curator: @scibot
  
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jneurosci.org/content/37/6/1413
May 2021
www.sciencedirect.com www.sciencedirect.com

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

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1. scibot 08 May 2021
  
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  RRID:AB_1961900
  
  DOI: 10.1016/j.neuron.2020.11.005
  
  Resource: (Cosmo Bio Cat# CAC-TIP-PTD-M01, RRID:AB_1961900)
  
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sciencedirect.com/science/article/pii/S0896627320308837
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1961900
  
  DOI: 10.1016/j.celrep.2019.05.085
  
  Resource: (Cosmo Bio Cat# CAC-TIP-PTD-M01, RRID:AB_1961900)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_1961900
  
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  RRID:AB_1961900 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719307247
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1961900
  
  DOI: 10.7554/eLife.39578
  
  Resource: (Cosmo Bio Cat# CAC-TIP-PTD-M01, RRID:AB_1961900)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_1961900
  
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  RRID:AB_1961900 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6426440/
Nov 2017
www.jneurosci.org www.jneurosci.org

Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis

1
1. scibot 08 Nov 2017
  
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  AB_1961900
  
  Curator: @chewbeccax
  
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  (Cosmo Bio Co Cat# CAC-TIP-PTD-M01, RRID:AB_1961900)
  
  SciCrunch record: RRID:AB_1961900
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_1961900 RRIDCUR:Validated
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jneurosci.org/content/37/6/1413