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The insulin/IGF axis is critically important for controlling gene transcription in the podocyte

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1. scibot 09 Sep 2026
  
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  DOI: 10.7554/eLife.107791
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13544910/
Aug 2026
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Single-nucleus RNA sequencing reveals transcriptional heterogeneity in the blastema of favorable-histology Wilms tumor

1
1. scibot 14 Aug 2026
  
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  DOI: 10.1172/jci.insight.188078
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13463612/
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Elongating human heart organoids recapitulate early cardiac morphogenesis and axial organization

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1. scibot 12 Aug 2026
  
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  DOI: 10.1016/j.devcel.2026.07.015
  
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sciencedirect.com/science/article/pii/S1534580726002844
Jul 2026
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Human iPSC-derived engineered heart tissue model of diastolic dysfunction in heart failure with preserved ejection fraction

1
1. scibot 18 Jul 2026
  
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  DOI: 10.1016/j.stem.2026.06.007
  
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sciencedirect.com/science/article/pii/S1934590926002341
Jun 2026
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Rat cell-derived kidney generation via interspecies blastocyst complementation in an Osr1-KO mouse model

1
1. scibot 13 Jun 2026
  
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  DOI: 10.1016/j.stemcr.2026.102957
  
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sciencedirect.com/science/article/pii/S2213671126001682
May 2026
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Human PSC-derived sinoatrial node-cardiac plexus assembloids model innervation-associated maturation of pacemaker systems

1
1. scibot 16 May 2026
  
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  DOI: 10.1016/j.stem.2026.04.018
  
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sciencedirect.com/science/article/pii/S193459092600158X
Apr 2026
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TRIM27-controlled endothelium-derived exosomes play a central role in podocyte injury in diabetic kidney disease

1
1. scibot 03 Apr 2026
  
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  DOI: 10.1038/s41420-026-02953-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13039385/
Mar 2026
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Modeling embryonic heart vascular plexus development and sympathetic innervation on a human heart organoid

1
1. scibot 21 Mar 2026
  
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  DOI: 10.1016/j.isci.2026.115071
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12996818/
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Developmental reprogramming underlies chemotherapy resistance in favorable-histology Wilms tumor

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1. scibot 20 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117063
  
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sciencedirect.com/science/article/pii/S2211124726001415
Jan 2026
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MYRF controls mesothelium specification, signaling, and plasticity in lung development

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1. scibot 22 Jan 2026
  
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  DOI: 10.1016/j.devcel.2025.12.011
  
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sciencedirect.com/science/article/pii/S1534580725007725
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Stc1-expressing myofibroblasts are a developmentally distinct lineage cleared through apoptosis in the neonatal lung

1
1. scibot 23 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116750
  
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sciencedirect.com:5037/science/article/pii/S2211124725015220
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Increased in vivo transduction of AAV-9 cargo in Alport podocytes

2
1. scibot 19 Dec 2025
  
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  RRID:AB_2043
  
  DOI: 10.12688/wellcomeopenres.24212.1
  
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2. scibot 19 Dec 2025
  
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  DOI: 10.12688/wellcomeopenres.24212.1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12699215/
Sep 2025
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Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling

1
1. scibot 18 Sep 2025
  
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  DOI: 10.1016/j.stem.2025.08.013
  
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sciencedirect.com/science/article/pii/S1934590925003285
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Lineage-Specific Epigenomic Mapping of Proximal and Distal Fallopian Tube Epithelium Reveals Mesenchymal/Wnt-Driven Tumor Phenotype Diversification

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1. scibot 06 Sep 2025
  
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  DOI: 10.1101/2025.08.27.672603
  
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biorxiv.org/content/10.1101/2025.08.27.672603v1
Jul 2025
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Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids

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1. scibot 01 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.05.041
  
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sciencedirect.com/science/article/pii/S0092867425006282
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Aged and BRCA-Mutated Stromal Cells Drive Epithelial Cell Transformation

1
1. scibot 11 Jun 2025
  
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  DOI: 10.1158/2159-8290.CD-24-0805
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12130807/
May 2025
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 20 May 2025
  
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  DOI: 10.1101/2025.04.28.650965
  
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52.53.155.43/eece82aa80cc33920a2274a22621cb502dabb6c9/PDF-html.html
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A retinoic acid:YAP1 signaling axis controls atrial lineage commitment

1
1. scibot 17 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115687
  
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sciencedirect.com/science/article/pii/S2211124725004589
Apr 2025
www.nature.com www.nature.com

Glucagon like peptide-1 modulates urinary sodium excretion in diabetic kidney disease via ENaC activation

1
1. scibot 06 Apr 2025
  
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  DOI: 10.1038/s41598-025-95673-9
  
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nature.com/articles/s41598-025-95673-9
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A spatiotemporal cell atlas of cardiopulmonary progenitor cell allocation during development

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1. scibot 03 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115513
  
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sciencedirect.com/science/article/pii/S2211124725002840
Feb 2025
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PPM1G dephosphorylates α-catenin to maintain the integrity of adherens junctions and regulates apoptosis in Sertoli cells

1
1. scibot 13 Feb 2025
  
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  DOI: 10.1016/j.mce.2025.112493
  
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sciencedirect.com/science/article/pii/S0303720725000449
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Maturation of human cardiac organoids enables complex disease modelling and drug discovery

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1. scibot 06 Feb 2025
  
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  RRID:AB_2043201
  
  DOI: 10.1101/2024.09.05.611336
  
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52.53.155.43/2a3cc686934257c062697951b2a037bb697f8dd7/2024.09.05.611336v1.full-html.html
Jan 2025
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Neutrophil extracellular traps promote pre-metastatic niche formation in the omentum by expanding innate-like B cells that express IL-10

1
1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.ccell.2024.12.004
  
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sciencedirect.com/science/article/pii/S1535610824004793
Aug 2024
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Chinese medicine Linggui Zhugan formula protects against diabetic kidney disease in close association with inhibition of proteinase 3-mediated podocyte apoptosis in mice

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1. scibot 19 Aug 2024
  
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  DOI: 10.1016/j.jep.2024.118650
  
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sciencedirect.com/science/article/pii/S0378874124009498
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Loss of Fbxw7 in Sertoli cells impairs testis development and causes infertility in mice

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1. scibot 02 Aug 2024
  
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  DOI: 10.1093/biolre/ioz230
  
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academic.oup.com/biolreprod/biolreprod/advance-article-abstract/doi/10.1093/biolre/ioz230/5688712
Jul 2024
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Heterozygous Gnaq deficiency enhances Ifi202b/IFI16 and NF-κB activation in endothelial cells and exacerbates lupus nephritis pathology

1
1. scibot 24 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110350
  
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sciencedirect.com/science/article/pii/S258900422401575X
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Generation of a homozygous (MCRIi031-A-3) WT1 knockout human iPSC line

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1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.scr.2024.103494
  
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sciencedirect.com/science/article/pii/S1873506124001922
May 2024
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Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease

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1. scibot 01 May 2024
  
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  DOI: 10.1016/j.stem.2024.04.002
  
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  DOI: 10.1016/j.stem.2024.04.002
  
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sciencedirect.com/science/article/pii/S1934590924001292
Apr 2024
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DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice

2
1. scibot 24 Apr 2024
  
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  DOI: 10.1016/j.devcel.2024.04.002
  
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  DOI: 10.1016/j.devcel.2024.04.002
  
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sciencedirect.com/science/article/pii/S1534580724002272
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hnRNPU is required for spermatogonial stem cell pool establishment in mice

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1. scibot 19 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114113
  
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sciencedirect.com/science/article/pii/S2211124724004418
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Genetic or pharmacologic blockade of mPGES-2 attenuates renal lipotoxicity and diabetic kidney disease by targeting Rev-Erbα/FABP5 signaling

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1. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114075
  
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sciencedirect.com/science/article/pii/S2211124724004030
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NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo

1
1. scibot 05 Apr 2024
  
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  DOI: 10.1016/j.stem.2024.03.003
  
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sciencedirect.com/science/article/pii/S1934590924000845
Feb 2024
aacrjournals.org aacrjournals.org

A novel irreversible TEAD inhibitor, SWTX-143, blocks Hippo pathway transcriptional output and causes tumor regression in preclinical mesothelioma models

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1. scibot 24 Feb 2024
  
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  DOI: 10.1158/1535-7163.MCT-22-0681
  
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hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility

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The importance of proinflammatory failed-repair tubular epithelia as a predictor of diabetic kidney disease progression

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Identification of a core transcriptional program driving the human renal mesenchymal-to-epithelial transition

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Characterization of the human fetal gonad and reproductive tract by single-cell transcriptomics

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In vivo characterization of a podocyte-expressed short podocin isoform

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mct-22-0681-html.html

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Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis

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Nestin identifies a subpopulation of rat ventricular fibroblasts and participates in cell migration

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A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids

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IL-17C neutralization protects the kidney against acute injury and chronic injury

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Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease

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Reconstitution of human adrenocortical specification and steroidogenesis using induced pluripotent stem cells

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Integration of single-cell transcriptome and chromatin accessibility of early gonads development among goats, pigs, macaques, and humans

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Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy

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A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery

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A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells

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The developmental origin and the specification of the adrenal cortex in humans and cynomolgus monkeys

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Directed differentiation of human pluripotent stem cells to epicardial-derived fibroblasts

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Suspension culture promotes serosal mesothelial development in human intestinal organoids

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Oviduct epithelial cells constitute two developmentally distinct lineages that are spatially separated along the distal-proximal axis

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Spatial transcriptional mapping of the human nephrogenic program

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Untitled document

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Novel Function of a Transcription Factor WT1 in Regulating Decidualization in Human Endometrial Stromal Cells and Its Molecular Mechanism

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Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis

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In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes

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A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles

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Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network

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Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche That Maintains and Replenishes Splenic Red Pulp Macrophages

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The embryonic ontogeny of the gonadal somatic cells in mice and monkeys

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Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1

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A molecular mechanism explaining albuminuria in kidney disease

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Sep 2020
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Multipotent Vascular Progenitor Cells of the Mesothelium Lineage Generated from Human Pluripotent Stem Cells

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Dynamic Interstitial Cell Response during Myocardial Infarction Predicts Resilience to Rupture in Genetically Diverse Mice

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A Modular Differentiation System Maps Multiple Human Kidney Lineages from Pluripotent Stem Cells

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Single-Cell Transcriptomic Atlas of Primate Ovarian Aging

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  DOI: 10.1016/j.cell.2020.01.009
  
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A Second Heart Field-Derived Vasculogenic Niche Contributes to Cardiac Lymphatics

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  DOI: 10.1016/j.devcel.2019.12.006
  
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Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells

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  DOI: 10.1016/j.celrep.2019.11.047
  
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Nov 2018
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Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis

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Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development

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Single-Cell RNA-Seq Analysis Maps Development of Human Germline Cells and Gonadal Niche Interactions

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1. scibot 08 Nov 2017
  
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