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www.biorxiv.org www.biorxiv.org

Lipid mediated ER-stress contributes to the pathogenesis of mitochondrial myopathies

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1. scibot 26 Jun 2026
  
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  DOI: 10.64898/2026.06.10.731336
  
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biorxiv.org/content/10.64898/2026.06.10.731336v1
Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tumor metabolic adaptation induced by L-asparaginase reveals a vulnerability to PARP1/2 inhibitor in B-cell lymphomas

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1. scibot 15 Apr 2026
  
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  DOI: 10.1038/s41467-026-70066-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13065833/
Feb 2026
www.sciencedirect.com www.sciencedirect.com

Asparagine sensing by TBK1 controls its phase separation to drive antiviral innate immune responses

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1. scibot 10 Feb 2026
  
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  DOI: 10.1016/j.molcel.2026.01.010
  
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sciencedirect.com/science/article/pii/S1097276526000304
Oct 2025
www.biorxiv.org www.biorxiv.org

L-asparaginase treatment induces a tumor metabolic plasticity and reveals a vulnerability to PARP1/2 inhibitor Olaparib, in B-cell lymphomas

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1. scibot 30 Oct 2025
  
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  RRID:AB_2060119
  
  DOI: 10.1101/2025.10.24.683536
  
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biorxiv.org/content/10.1101/2025.10.24.683536v1
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PI5P4Kα promotes glucose and iron acquisition to support metabolic fitness in pancreatic cancer

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1. scibot 30 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116199
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12622763/
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

MYC Drives mRNA Pseudouridylation to Mitigate Proliferation-Induced Cellular Stress during Cancer Development

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1. scibot 12 Dec 2024
  
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  DOI: 10.1158/0008-5472.CAN-24-1102
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11609627/
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Targeting NAT10 inhibits osteosarcoma progression via ATF4/ASNS-mediated asparagine biosynthesis

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.xcrm.2024.101728
  
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sciencedirect.com/science/article/pii/S2666379124004555
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors

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1. scibot 06 Dec 2023
  
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  RRID:AB_2060119
  
  DOI: 10.1158/1078-0432.CCR-23-1182
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10690095/
Oct 2023
52.53.155.43 52.53.155.43

ccr-23-1182-html.html

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1. scibot 07 Oct 2023
  
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  DOI: 10.1158/1078-0432.ccr-23-1182
  
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52.53.155.43/65c36a5cdd4f77902b5a0c626487c84333ec98dd/ccr-23-1182-html.html
May 2023
www.embopress.org www.embopress.org

A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy

1
1. scibot 25 May 2023
  
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  RRID:AB_2060119
  
  DOI: 10.15252/emmm.202216951
  
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embopress.org/doi/full/10.15252/emmm.202216951
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Asparagine starvation suppresses histone demethylation through iron depletion

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1. scibot 09 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106425
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10074807/
Jul 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tumoral microenvironment prevents de novo asparagine biosynthesis in B cell lymphoma, regardless of ASNS expression

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1. scibot 27 Jul 2022
  
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  DOI: 10.1126/sciadv.abn6491
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9258813/
Apr 2022
www.sciencedirect.com www.sciencedirect.com

Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis

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1. scibot 07 Apr 2022
  
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  RRID:AB_2060119
  
  DOI: 10.1016/j.molcel.2022.03.016
  
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sciencedirect.com/science/article/pii/S1097276522002544
May 2021
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Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth

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1. scibot 01 May 2021
  
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  DOI: 10.1016/j.cmet.2021.02.001
  
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sciencedirect.com/science/article/pii/S1550413121000577
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Asparagine Synthetase-Mediated l-Asparagine Metabolism Disorder Promotes the Perineural Invasion of Oral Squamous Cell Carcinoma

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1. scibot 28 Mar 2021
  
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  RRID:AB_2060119
  
  DOI: 10.3389/fonc.2021.637226
  
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  Curator: @evieth
  
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  RRID:AB_2060119 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7987891/
Sep 2020
www.sciencedirect.com www.sciencedirect.com

ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase

1
1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.cmet.2020.03.008
  
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  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:AB_2060119
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sciencedirect.com/science/article/pii/S1550413120301236
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2060119
  
  DOI: 10.1016/j.celrep.2019.08.076
  
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  Curator: @ethanbadger
  
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  RRID:AB_2060119 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719311313