92 Matching Annotations
  1. Sep 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A cell-autonomous role for primary cilium-mediated signaling in long-range commissural axon guidance
    1
    1. scibot 27 Sep 2024
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      DOI: 10.1242/dev.202788

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    ncbi.nlm.nih.gov/pmc/articles/PMC11423920/
  3. Jul 2024
  4. 52.53.155.43 52.53.155.43
    1-s2.0-S258900422401825X-main-html.html
    1
    1. scibot 30 Jul 2024
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  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective targeting of mu opioid receptors to primary cilia
    1
    1. scibot 20 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114164

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    ncbi.nlm.nih.gov/pmc/articles/PMC11257377/
  6. Jun 2024
  7. link.springer.com link.springer.com
    Astrocyte-Specific Inhibition of the Primary Cilium Suppresses C3 Expression in Reactive Astrocyte
    1
    1. scibot 04 Jun 2024
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      DOI: 10.1007/s10571-024-01482-5

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    link.springer.com/article/10.1007/s10571-024-01482-5
  8. May 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Generation of FOXJ1-EGFP knock-in reporter human embryonic stem cell line, WAe001-A-2D, using CRISPR/Cas9-based gene targeting
    1
    1. scibot 30 May 2024
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    sciencedirect.com/science/article/pii/S1873506124001430
  10. 52.53.155.43 52.53.155.43
    Rediscovering the Rete Ovarii: a secreting auxiliary structure to the ovary
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    1. scibot 02 May 2024
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      DOI: 10.1101/2023.11.08.566085

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  11. Apr 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function
    1
    1. scibot 30 Apr 2024
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      DOI: 10.1101/2024.04.02.587836

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014585/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Numb positively regulates Hedgehog signaling at the ciliary pocket
    1
    1. scibot 29 Apr 2024
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      DOI: 10.1038/s41467-024-47244-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11045789/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of the disease-causing mechanism of KIF3B mutations from ciliopathy patients
    1
    1. scibot 28 Apr 2024
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      DOI: 10.3389/fmolb.2024.1327963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11043552/
  15. Mar 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Primary cilia as a tumor marker in pituitary neuroendocrine tumors
    2
    1. scibot 21 Mar 2024
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      DOI: 10.1016/j.modpat.2024.100475

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      DOI: 10.1016/j.modpat.2024.100475

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    sciencedirect.com/science/article/pii/S0893395224000553
  17. www.sciencedirect.com www.sciencedirect.com
    In vivo CRISPR screening directly targeting testicular cells
    1
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.xgen.2024.100510

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    sciencedirect.com/science/article/pii/S2666979X24000375
  18. www.sciencedirect.com www.sciencedirect.com
    A sterol analog inhibits hedgehog pathway by blocking cholesterylation of smoothened
    3
    1. scibot 05 Mar 2024
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      DOI: 10.1016/j.chembiol.2024.02.002

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    2. scibot 05 Mar 2024
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      DOI: 10.1016/j.chembiol.2024.02.002

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    3. scibot 05 Mar 2024
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      DOI: 10.1016/j.chembiol.2024.02.002

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    sciencedirect.com/science/article/pii/S245194562400076X
  19. Feb 2024
  20. www.sciencedirect.com www.sciencedirect.com
    ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells
    1
    1. scibot 29 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113818

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    sciencedirect.com/science/article/pii/S2211124724001463
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KIF3A tail domain phosphorylation is not required for ciliogenesis in mouse embryonic fibroblasts
    1
    1. scibot 28 Feb 2024
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      DOI: 10.1016/j.isci.2024.109149

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    ncbi.nlm.nih.gov/pmc/articles/PMC10884758/
  22. www.sciencedirect.com www.sciencedirect.com
    DPCD is a regulator of R2TP in ciliogenesis initiation through Akt signaling
    2
    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113713

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    2. scibot 02 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113713

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    sciencedirect.com/science/article/pii/S221112472400041X
  23. Jan 2024
  24. www.sciencedirect.com www.sciencedirect.com
    Cytoneme signaling provides essential contributions to mammalian tissue patterning
    1
    1. scibot 07 Jan 2024
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      DOI: 10.1016/j.cell.2023.12.003

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    sciencedirect.com/science/article/pii/S0092867423013338
  25. Dec 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Bi-allelic variants in CEP295 cause Seckel-like syndrome presenting with primary microcephaly, developmental delay, intellectual disability, short stature, craniofacial and digital abnormalities
    1
    1. scibot 29 Dec 2023
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      DOI: 10.1016/j.ebiom.2023.104940

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    sciencedirect.com/science/article/pii/S2352396423005066
  27. www.sciencedirect.com www.sciencedirect.com
    Human iPSC-derived renal collecting duct organoid model cystogenesis in ADPKD
    1
    1. scibot 02 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113431

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    sciencedirect.com/science/article/pii/S2211124723014432
  28. Oct 2023
  29. www.sciencedirect.com www.sciencedirect.com
    MiniBAR/GARRE1 is a dual Rac and Rab effector required for ciliogenesis
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.devcel.2023.09.010

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    sciencedirect.com/science/article/pii/S1534580723005129
  30. www.sciencedirect.com www.sciencedirect.com
    Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.devcel.2023.09.008

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    sciencedirect.com/science/article/pii/S1534580723004951
  31. www.sciencedirect.com www.sciencedirect.com
    Primary cilia control oligodendrocyte precursor cell proliferation in white matter injury via Hedgehog-independent CREB signaling
    1
    1. scibot 27 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113272

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    sciencedirect.com/science/article/pii/S2211124723012846
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.112845

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    ncbi.nlm.nih.gov/pmc/articles/PMC10521973/
  33. Sep 2023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Beta cell primary cilia mediate somatostatin responsiveness via SSTR3
    1
    1. scibot 07 Sep 2023
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      DOI: 10.1080/19382014.2023.2252855

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    ncbi.nlm.nih.gov/pmc/articles/PMC10478741/
  35. Aug 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1
    1
    1. scibot 10 Aug 2023
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      DOI: 10.1016/j.isci.2023.107446

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    sciencedirect.com/science/article/pii/S2589004223015237
  37. Jun 2023
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Calcium dynamics at the neural cell primary cilium regulate Hedgehog signaling–dependent neurogenesis in the embryonic neural tube
    1
    1. scibot 17 Jun 2023
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      DOI: 10.1073/pnas.2220037120

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    ncbi.nlm.nih.gov/pmc/articles/PMC10266006/
  39. May 2023
  40. www.nature.com www.nature.com
    Table 3 Antibodies
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    1. scibot 18 May 2023
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      DOI: 10.1038/s41596-023-00814-x

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    nature.com/articles/s41596-023-00814-x/tables/3
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Calcineurin associates with centrosomes and regulates cilia length maintenance
    1
    1. scibot 09 May 2023
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      DOI: 10.1242/jcs.260353

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    ncbi.nlm.nih.gov/pmc/articles/PMC10163345/
  42. Apr 2023
  43. www.sciencedirect.com www.sciencedirect.com
    Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling
    1
    1. scibot 27 Apr 2023
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      DOI: 10.1016/j.devcel.2023.04.005

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    sciencedirect.com/science/article/pii/S1534580723001582
  44. Feb 2023
  45. www.mdpi.com www.mdpi.com
    Evaluation of Epithelial–Mesenchymal Transition Markers in Autoimmune Thyroid Diseases
    1
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      DOI: 10.3390/ijms24043359

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    mdpi.com/1422-0067/24/4/3359
  46. www.cell.com www.cell.com
    The developmental basis of fingerprint pattern formation and variation
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      DOI: 10.1016/j.cell.2023.01.015

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    cell.com/cell/fulltext/S0092-8674(23)00045-4
  47. Jan 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis
    1
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      DOI: 10.1016/j.devcel.2022.12.006

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    sciencedirect.com/science/article/pii/S1534580722008723
  49. Dec 2022
  50. www.embopress.org www.embopress.org
    GRAMD1/ASTER-mediated cholesterol transport promotes Smoothened cholesterylation at the endoplasmic reticulum
    1
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      DOI: 10.15252/embj.2022111513

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    embopress.org/doi/10.15252/embj.2022111513
  51. www.sciencedirect.com www.sciencedirect.com
    IFT-A structure reveals carriages for membrane protein transport into cilia
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      DOI: 10.1016/j.cell.2022.11.010

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    sciencedirect.com/science/article/pii/S0092867422014222
  52. Nov 2022
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of Primary Cilium Expression and Hedgehog Pathway Activation in Mesothelioma Throws Back Its Complex Biology
    1
    1. scibot 18 Nov 2022
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      DOI: 10.3390/cancers14215216

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    ncbi.nlm.nih.gov/pmc/articles/PMC9654223/
  54. journals.biologists.com journals.biologists.com
    Disease-associated mutations in WDR34 lead to diverse impacts on the assembly and function of dynein-2
    1
    1. scibot 12 Nov 2022
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      DOI: 10.1242/jcs.260073

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    journals.biologists.com/jcs/article/136/5/jcs260073/280974/Disease-associated-mutations-in-WDR34-lead-to
  55. www.sciencedirect.com www.sciencedirect.com
    CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors
    1
    1. scibot 05 Nov 2022
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      DOI: 10.1016/j.neuron.2022.10.018

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    sciencedirect.com/science/article/pii/S0896627322009473
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    A high-throughput electron tomography workflow reveals over-elongated centrioles in relapsed/refractory multiple myeloma
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  57. Oct 2022
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    Metabolomic fingerprinting of renal disease progression in Bardet-Biedl syndrome reveals mitochondrial dysfunction in kidney tubular cells
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  59. Jun 2022
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    Pathogenic LRRK2 regulates centrosome cohesion via Rab10/RILPL1-mediated CDK5RAP2 displacement
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  61. May 2022
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    The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling
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  63. Apr 2022
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  66. Feb 2022
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    ExSTED microscopy reveals contrasting functions of dopamine and somatostatin CSF-c neurons along the lamprey central canal
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  69. Jan 2022
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    C2cd6-encoded CatSperτ targets sperm calcium channel to Ca2+ signaling domains in the flagellar membrane
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  71. Dec 2021
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  73. Nov 2021
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    Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis
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  75. Oct 2021
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  77. Sep 2021
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  79. Aug 2021
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  83. Jul 2021
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    Centrosome-derived microtubule radial array, PCM-1 protein, and primary cilia formation
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    A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice
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    Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia
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    TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity
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    Targeting an anchored phosphatase-deacetylase unit restores renal ciliary homeostasis
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    Myocardin-related transcription factor and serum response factor regulate cilium turnover by both transcriptional and local mechanisms
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  90. May 2021
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    Rab34 is necessary for early stages of intracellular ciliogenesis
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    Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway
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    Serotonin Receptor 2A Activation Promotes Evolutionarily Relevant Basal Progenitor Proliferation in the Developing Neocortex
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    Comparative Super-Resolution Mapping of Basal Feet Reveals a Modular but Distinct Architecture in Primary and Motile Cilia
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  97. Mar 2021
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  99. Dec 2020
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    Gpr37l1/prosaposin receptor regulates Ptch1 trafficking, Shh production, and cell proliferation in cerebellar primary astrocytes
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  101. Oct 2020
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    Live imaging of hair bundle polarity acquisition demonstrates a critical timeline for transcription factor Emx2
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  103. Sep 2020
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    The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis
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    Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade
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  109. Jan 2020
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    Decreased Expression of Cilia Genes in Pancreatic Islets as a Risk Factor for Type 2 Diabetes in Mice and Humans
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  117. Nov 2018
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    EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation
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    Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination
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    Insm1 Induces Neural Progenitor Delamination in Developing Neocortex via Downregulation of the Adherens Junction Belt-Specific Protein Plekha7
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    Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways
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    The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base
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    Reduced primary cilia length and altered Arl13b expression are associated with deregulated chondrocyte Hedgehog signaling in alkaptonuria
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    Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision
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