37 Matching Annotations
  1. May 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia
    1
    1. scibot 16 May 2024
      RRID:AB_2060983

      DOI: 10.1016/j.celrep.2024.114237

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    sciencedirect.com/science/article/pii/S2211124724005655
  3. Apr 2024
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    Restoring thalamocortical circuit dysfunction by correcting HCN channelopathy in Shank3 mutant mice
    1
    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.xcrm.2024.101534

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    sciencedirect.com/science/article/pii/S2666379124002039
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    A p85 isoform switch enhances PI3K activation on endosomes by a MAP4- and PI3P-dependent mechanism
    1
    1. scibot 18 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114119

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    sciencedirect.com/science/article/pii/S2211124724004479
  6. Mar 2024
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    Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion
    1
    1. scibot 28 Mar 2024
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      DOI: 10.1016/j.celrep.2024.114002

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    sciencedirect.com/science/article/pii/S2211124724003309
  8. Feb 2024
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    ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells
    1
    1. scibot 29 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113818

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    sciencedirect.com/science/article/pii/S2211124724001463
  10. Jan 2024
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    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.jbc.2024.105641

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    sciencedirect.com/science/article/pii/S0021925824000176
  12. Nov 2022
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    Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization
    1
    1. scibot 03 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111580

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    sciencedirect.com/science/article/pii/S2211124722014413
  14. Oct 2022
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repeated inhibition of sigma-1 receptor suppresses GABAA receptor expression and long-term depression in the nucleus accumbens leading to depressive-like behaviors
    1
    1. scibot 26 Oct 2022
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      DOI: 10.3389/fnmol.2022.959224

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    ncbi.nlm.nih.gov/pmc/articles/PMC9563353/
  16. Mar 2022
  17. www.sciencedirect.com www.sciencedirect.com
    Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake
    1
    1. scibot 16 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110509

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    sciencedirect.com/science/article/pii/S2211124722002455
  18. Jan 2022
  19. www.sciencedirect.com www.sciencedirect.com
    YAP1 and PRDM14 converge to promote cell survival and tumorigenesis
    1
    1. scibot 06 Jan 2022
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      DOI: 10.1016/j.devcel.2021.12.006

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    sciencedirect.com/science/article/pii/S1534580721009953
  20. Oct 2021
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    A synaptic temperature sensor for body cooling
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    1. scibot 21 Oct 2021
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      DOI: 10.1016/j.neuron.2021.10.001

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    sciencedirect.com/science/article/pii/S0896627321007698
  22. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Thioredoxin interacting protein drives astrocytic glucose hypometabolism in corticosterone-induced depressive state
    1
    1. scibot 20 Oct 2021
      RRID:AB_2060983

      DOI: 10.1111/jnc.15489

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15489
  23. Aug 2021
  24. www.sciencedirect.com www.sciencedirect.com
    Oligodendroglial ring finger protein Rnf43 is an essential injury-specific regulator of oligodendrocyte maturation
    1
    1. scibot 16 Aug 2021
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      DOI: 10.1016/j.neuron.2021.07.018

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    sciencedirect.com/science/article/pii/S0896627321005390
  25. www.sciencedirect.com www.sciencedirect.com
    Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation
    1
    1. scibot 09 Aug 2021
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      DOI: 10.1016/j.cmet.2018.07.019

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    sciencedirect.com/science/article/pii/S1550413118304625
  26. www.mdpi.com www.mdpi.com
    CRISPR/Cas9-Mediated Knock-Out of KrasG12D Mutated Pancreatic Cancer Cell Lines
    1
    1. scibot 03 Aug 2021
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      DOI: 10.3390/ijms20225706

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    mdpi.com/1422-0067/20/22/5706
  27. Jul 2021
  28. academic.oup.com academic.oup.com
    Conformational Change in the Ligand-Binding Pocket via a KISS1R Mutation (P147L) Leads to Isolated Gonadotropin-Releasing Hormone Deficiency
    1
    1. scibot 28 Jul 2021
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      DOI: 10.1210/js.2017-00277

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    academic.oup.com/jes/article/1/10/1259/4104404
  29. www.sciencedirect.com www.sciencedirect.com
    Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway
    1
    1. scibot 22 Jul 2021
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      DOI: 10.1016/j.cell.2021.06.028

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    sciencedirect.com/science/article/pii/S0092867421007960
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1
    1
    1. scibot 03 Jul 2021
      RRID:AB_2060983

      DOI: 10.7554/eLife.67123

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    ncbi.nlm.nih.gov/pmc/articles/PMC8225385/
  31. Jun 2021
  32. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Enhanced tyrosine hydroxylase activity induces oxidative stress, causes accumulation of autotoxic catecholamine metabolites, and augments amphetamine effects in vivo
    1
    1. scibot 25 Jun 2021
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      DOI: 10.1111/jnc.15432

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15432
  33. May 2021
  34. www.sciencedirect.com www.sciencedirect.com
    Creatine-mediated crosstalk between adipocytes and cancer cells regulates obesity-driven breast cancer
    1
    1. scibot 01 May 2021
      RRID:AB_2060983

      DOI: 10.1016/j.cmet.2021.01.018

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    sciencedirect.com/science/article/pii/S1550413121000565
  35. Apr 2021
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    Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance
    1
    1. scibot 22 Apr 2021
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      DOI: 10.1016/j.ccell.2020.12.023

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    sciencedirect.com/science/article/pii/S1535610820306711
  37. www.sciencedirect.com www.sciencedirect.com
    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
    1
    1. scibot 06 Apr 2021
      Anti-ATP1A1 antibody

      DOI: 10.1016/j.immuni.2021.02.020

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    sciencedirect.com/science/article/pii/S1074761321000868
  38. Mar 2021
  39. www.sciencedirect.com www.sciencedirect.com
    Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis
    1
    1. scibot 17 Mar 2021
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      DOI: 10.1016/j.celrep.2021.108873

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    sciencedirect.com/science/article/pii/S221112472100187X
  40. Feb 2021
  41. www.sciencedirect.com www.sciencedirect.com
    ALS-causing SOD1 mutants regulate occludin phosphorylation/ubiquitination and endocytic trafficking via the ITCH/Eps15/Rab5 axis
    1
    1. scibot 25 Feb 2021
      Na/K ATPase

      DOI: 10.1016/j.nbd.2021.105315

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    sciencedirect.com/science/article/pii/S0969996121000644
  42. pubs.rsc.org pubs.rsc.org
    The effect of quercetin on endothelial cells is modified by heterocellular interactions
    1
    1. scibot 25 Feb 2021
      RRID:AB_2060983

      DOI: 10.1039/D0FO00141D

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    pubs.rsc.org/en/content/articlehtml/2020/fo/d0fo00141d
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PKN1 Is a Novel Regulator of Hippocampal GluA1 Levels
    1
    1. scibot 24 Feb 2021
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      DOI: 10.3389/fnsyn.2021.640495

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    ncbi.nlm.nih.gov/pmc/articles/PMC7892898/
  44. Dec 2020
  45. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer’s Disease
    1
    1. scibot 07 Dec 2020
      RRID:AB_2060983

      DOI: 10.1016/j.celrep.2020.108420

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    pubmed.ncbi.nlm.nih.gov/33238112/
  46. Sep 2020
  47. www.sciencedirect.com www.sciencedirect.com
    Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation
    1
    1. scibot 14 Sep 2020
      RRID:AB_2060983

      DOI: 10.1016/j.cmet.2020.03.017

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    sciencedirect.com/science/article/pii/S1550413120301327
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes
    1
    1. scibot 13 Sep 2020
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      DOI: 10.1038/s41598-020-69913-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC7400764/
  49. www.sciencedirect.com www.sciencedirect.com
    Suppression of Membranous LRP5 Recycling, Wnt/β-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P
    1
    1. scibot 03 Sep 2020
      RRID:AB_2060983

      DOI: 10.1016/j.celrep.2020.108049

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    sciencedirect.com/science/article/pii/S2211124720310342
  50. Jan 2020
  51. academic.oup.com academic.oup.com
    Tubulin detyrosination promotes human trophoblast syncytium formation
    1
    1. scibot 13 Jan 2020
      RRID:AB_2060983

      DOI: 10.1093/jmcb/mjz084

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    academic.oup.com/jmcb/advance-article/doi/10.1093/jmcb/mjz084/5549368
  52. www.sciencedirect.com www.sciencedirect.com
    Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity
    1
    1. scibot 13 Jan 2020
      RRID:AB_2060983

      DOI: 10.1016/j.cmet.2019.01.011

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    sciencedirect.com/science/article/pii/S1550413119300117
  53. Nov 2018
  54. www.sciencedirect.com www.sciencedirect.com
    Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization
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    1. scibot 05 Nov 2018
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S009286741831033X
  55. academic.oup.com academic.oup.com
    cGMP/PKG-I Pathway–Mediated GLUT1/4 Regulation by NO in Female Rat Granulosa Cells
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    1. scibot 05 Nov 2018
      AB_2060983

      Curator: @evieth

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    academic.oup.com/endo/article/159/2/1147/4780795
  56. Nov 2017
  57. academic.oup.com academic.oup.com
    Untitled document
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    1. scibot 08 Nov 2017
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      Curator: @patriciaelyse_

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    academic.oup.com/jes/article/1/10/1259/4104404/Conformational-Change-in-the-Ligand-Binding-Pocket
  58. www.sciencedirect.com www.sciencedirect.com
    Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma
    1
    1. scibot 08 Nov 2017
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S153561081730346X
  59. elifesciences.org elifesciences.org
    SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation
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    1. scibot 08 Nov 2017
      AB_2060983

      Curator: @gabimpine

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    elifesciences.org/content/6/e25158