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Impaired MAPT/tau-secretory lysosomes are linked to cognitive vulnerability in Alzheimer patients

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1. scibot 03 Sep 2025
  
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  DOI: 10.1080/15548627.2025.2552905
  
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tandfonline.com/doi/full/10.1080/15548627.2025.2552905
Aug 2025
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Inhibition of tumor cell macropinocytosis driver DHODH reverses immunosuppression and overcomes anti-PD1 resistance

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1. scibot 15 Aug 2025
  
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  DOI: 10.1016/j.immuni.2025.07.013
  
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sciencedirect.com/science/article/pii/S107476132500322X
Jul 2025
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liu-et-al-2024-β3-adrenergic-agonist-counters-oxidative-stress-and-na-k-pump-inhibitory-s-glutathionylation-of-html.html

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1. scibot 19 Jul 2025
  
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  DOI: 10.1152/ajpcell.00379.2024
  
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52.53.155.43/aadf21d291525c53d00ab6bcff920d857884b5d8/liu-et-al-2024-β3-adrenergic-agonist-counters-oxidative-stress-and-na-k-pump-inhibitory-s-glutathionylation-of-html.html
May 2025
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Sex-and depot-specific differences in cellular insulin responsiveness during adipose expansion

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1. scibot 22 May 2025
  
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  DOI: 10.1016/j.lfs.2025.123743
  
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sciencedirect.com/science/article/pii/S0024320525003789
Apr 2025
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Structural basis of urate transport by glucose transporter 9

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  DOI: 10.1016/j.celrep.2025.115514
  
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sciencedirect.com/science/article/pii/S2211124725002852
Mar 2025
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Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape

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1. scibot 01 Mar 2025
  
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  DOI: 10.7554/eLife.95952
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11832170/
Feb 2025
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Disrupting AGR2/IGF1 paracrine and reciprocal signaling for pancreatic cancer therapy

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1. scibot 07 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2024.101927
  
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sciencedirect.com/science/article/pii/S2666379124006980
Jan 2025
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Age-associated interplay between zinc deficiency and Golgi stress hinders microtubule-dependent cellular signaling and epigenetic control

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1. scibot 07 Jan 2025
  
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  DOI: 10.1016/j.devcel.2024.12.024
  
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sciencedirect.com/science/article/pii/S1534580724007639
Aug 2024
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Epigenetic repression of de novo cysteine synthetases induces intra-cellular accumulation of cysteine in hepatocarcinoma by up-regulating the cystine uptake transporter xCT

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1. scibot 21 Aug 2024
  
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  DOI: 10.1186/s40170-024-00352-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11304919/
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Insect-transmitted plant virus balances its vertical transmission through regulating Rab1-mediated receptor localization

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1. scibot 18 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114571
  
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sciencedirect.com/science/article/pii/S2211124724009008
May 2024
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Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia

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1. scibot 16 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114237
  
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sciencedirect.com/science/article/pii/S2211124724005655
Apr 2024
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Restoring thalamocortical circuit dysfunction by correcting HCN channelopathy in Shank3 mutant mice

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1. scibot 30 Apr 2024
  
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  DOI: 10.1016/j.xcrm.2024.101534
  
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sciencedirect.com/science/article/pii/S2666379124002039
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A p85 isoform switch enhances PI3K activation on endosomes by a MAP4- and PI3P-dependent mechanism

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1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114119
  
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sciencedirect.com/science/article/pii/S2211124724004479
Mar 2024
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Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion

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1. scibot 28 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.114002
  
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sciencedirect.com/science/article/pii/S2211124724003309
Feb 2024
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ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells

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1. scibot 29 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113818
  
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sciencedirect.com/science/article/pii/S2211124724001463
Jan 2024
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Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease

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1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.jbc.2024.105641
  
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sciencedirect.com/science/article/pii/S0021925824000176
Nov 2022
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Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization

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1. scibot 03 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111580
  
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sciencedirect.com/science/article/pii/S2211124722014413
Oct 2022
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Repeated inhibition of sigma-1 receptor suppresses GABAA receptor expression and long-term depression in the nucleus accumbens leading to depressive-like behaviors

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1. scibot 26 Oct 2022
  
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  DOI: 10.3389/fnmol.2022.959224
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9563353/
Mar 2022
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Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake

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1. scibot 16 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110509
  
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sciencedirect.com/science/article/pii/S2211124722002455
Jan 2022
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YAP1 and PRDM14 converge to promote cell survival and tumorigenesis

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1. scibot 06 Jan 2022
  
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  DOI: 10.1016/j.devcel.2021.12.006
  
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sciencedirect.com/science/article/pii/S1534580721009953
Oct 2021
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A synaptic temperature sensor for body cooling

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  DOI: 10.1016/j.neuron.2021.10.001
  
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sciencedirect.com/science/article/pii/S0896627321007698
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Thioredoxin interacting protein drives astrocytic glucose hypometabolism in corticosterone-induced depressive state

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1. scibot 20 Oct 2021
  
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  DOI: 10.1111/jnc.15489
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15489
Aug 2021
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Oligodendroglial ring finger protein Rnf43 is an essential injury-specific regulator of oligodendrocyte maturation

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1. scibot 16 Aug 2021
  
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  DOI: 10.1016/j.neuron.2021.07.018
  
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sciencedirect.com/science/article/pii/S0896627321005390
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Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation

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1. scibot 09 Aug 2021
  
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  DOI: 10.1016/j.cmet.2018.07.019
  
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sciencedirect.com/science/article/pii/S1550413118304625
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CRISPR/Cas9-Mediated Knock-Out of KrasG12D Mutated Pancreatic Cancer Cell Lines

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1. scibot 03 Aug 2021
  
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  DOI: 10.3390/ijms20225706
  
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mdpi.com/1422-0067/20/22/5706
Jul 2021
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Conformational Change in the Ligand-Binding Pocket via a KISS1R Mutation (P147L) Leads to Isolated Gonadotropin-Releasing Hormone Deficiency

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1. scibot 28 Jul 2021
  
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  DOI: 10.1210/js.2017-00277
  
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academic.oup.com/jes/article/1/10/1259/4104404
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Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway

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1. scibot 22 Jul 2021
  
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  DOI: 10.1016/j.cell.2021.06.028
  
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sciencedirect.com/science/article/pii/S0092867421007960
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T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1

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1. scibot 03 Jul 2021
  
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  DOI: 10.7554/eLife.67123
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8225385/
Jun 2021
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Enhanced tyrosine hydroxylase activity induces oxidative stress, causes accumulation of autotoxic catecholamine metabolites, and augments amphetamine effects in vivo

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1. scibot 25 Jun 2021
  
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  DOI: 10.1111/jnc.15432
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15432
May 2021
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Creatine-mediated crosstalk between adipocytes and cancer cells regulates obesity-driven breast cancer

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  DOI: 10.1016/j.cmet.2021.01.018
  
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sciencedirect.com/science/article/pii/S1550413121000565
Apr 2021
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Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance

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1. scibot 22 Apr 2021
  
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  DOI: 10.1016/j.ccell.2020.12.023
  
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sciencedirect.com/science/article/pii/S1535610820306711
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Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer

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1. scibot 06 Apr 2021
  
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  Anti-ATP1A1 antibody
  
  DOI: 10.1016/j.immuni.2021.02.020
  
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sciencedirect.com/science/article/pii/S1074761321000868
Mar 2021
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Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis

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1. scibot 17 Mar 2021
  
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  DOI: 10.1016/j.celrep.2021.108873
  
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sciencedirect.com/science/article/pii/S221112472100187X
Feb 2021
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ALS-causing SOD1 mutants regulate occludin phosphorylation/ubiquitination and endocytic trafficking via the ITCH/Eps15/Rab5 axis

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1. scibot 25 Feb 2021
  
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  Na/K ATPase
  
  DOI: 10.1016/j.nbd.2021.105315
  
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sciencedirect.com/science/article/pii/S0969996121000644
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The effect of quercetin on endothelial cells is modified by heterocellular interactions

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1. scibot 25 Feb 2021
  
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  DOI: 10.1039/D0FO00141D
  
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PKN1 Is a Novel Regulator of Hippocampal GluA1 Levels

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  DOI: 10.3389/fnsyn.2021.640495
  
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Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer’s Disease

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Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation

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GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes

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  DOI: 10.1038/s41598-020-69913-z
  
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Suppression of Membranous LRP5 Recycling, Wnt/β-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P

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Tubulin detyrosination promotes human trophoblast syncytium formation

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  DOI: 10.1093/jmcb/mjz084
  
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Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity

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Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization

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cGMP/PKG-I Pathway–Mediated GLUT1/4 Regulation by NO in Female Rat Granulosa Cells

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Nov 2017
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Untitled document

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Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma

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SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation

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