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WEE1 kinase inhibition to overcome acquired resistance to targeted therapies in colorectal cancer

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1. scibot 18 Jun 2026
  
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  DOI: 10.1038/s44321-026-00434-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13269805/
Jan 2026
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The FANCD2-FANCI heterodimer coordinates chromatin openness and cell cycle progression throughout DNA double-strand break repair

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116830
  
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sciencedirect.com/science/article/pii/S221112472501602X
Jul 2025
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KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.ccell.2025.06.011
  
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sciencedirect.com/science/article/pii/S1535610825002612
May 2025
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Circular RNA circATM binds PARP1 to suppress Wnt/β-catenin signaling and induce cell cycle arrest in gastric cancer cells

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.jare.2025.04.033
  
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Apr 2025
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Treacle’s ability to form liquid-like phase condensates is essential for nucleolar fibrillar center assembly, efficient rRNA transcription and processing, and rRNA gene repair

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1. scibot 16 Apr 2025
  
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  DOI: 10.7554/eLife.96722
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11996177/
Jan 2025
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Co-essentiality analysis identifies PRR12 as a cohesin interacting protein and contributor to genomic integrity

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.devcel.2024.12.015
  
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sciencedirect.com/science/article/pii/S1534580724007378
Nov 2024
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p21 regulates expression of ECM components and promotes pulmonary fibrosis via CDK4 and Rb

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1. scibot 21 Nov 2024
  
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  DOI: 10.1038/s44318-024-00246-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11574164/
Aug 2024
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Schlafen 11 further sensitizes BRCA-deficient cells to PARP inhibitors through single-strand DNA gap accumulation behind replication forks

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1. scibot 21 Aug 2024
  
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  DOI: 10.1038/s41388-024-03094-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11315672/
Mar 2024
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CDK-independent role of D-type cyclins in regulating DNA mismatch repair

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1. scibot 08 Mar 2024
  
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  DOI: 10.1016/j.molcel.2024.02.010
  
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2. scibot 08 Mar 2024
  
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  DOI: 10.1016/j.molcel.2024.02.010
  
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sciencedirect.com/science/article/pii/S1097276524001291
Feb 2024
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β1 integrin mediates unresponsiveness to PI3Kα inhibition for radiochemosensitization of 3D HNSCC models

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1. scibot 02 Feb 2024
  
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  DOI: 10.1016/j.biopha.2024.116217
  
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sciencedirect.com/science/article/pii/S0753332224000982
Aug 2023
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Nuclear transport surveillance of p53 by nuclear pores in glioblastoma

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1. scibot 12 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112882
  
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2. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112882
  
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52.53.155.43/64ae675a86b73874b1bb5c50aa8d9678e93e36d6/PIIS2211124723008938-html.html
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FACS-based genome-wide CRISPR screens define key regulators of DNA damage signaling pathways

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1. scibot 04 Aug 2023
  
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  DOI: 10.1016/j.molcel.2023.07.004
  
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sciencedirect.com/science/article/abs/pii/S109727652300518X
Jan 2023
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Loss of epigenetic information as a cause of mammalian aging

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1. scibot 19 Jan 2023
  
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  DOI: 10.1016/j.cell.2022.12.027
  
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cell.com/cell/fulltext/S0092-8674(22)01570-7
Nov 2022
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Manganese enhances DNA- or RNA-mediated innate immune response by inducing phosphorylation of TANK-binding kinase 1

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1. scibot 04 Nov 2022
  
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  DOI: 10.1016/j.isci.2022.105352
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9619380/
Aug 2021
www.embopress.org www.embopress.org

Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway

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1. scibot 05 Aug 2021
  
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  DOI: 10.15252/embj.2020107413
  
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embopress.org/doi/abs/10.15252/embj.2020107413
Apr 2021
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Opening of cohesin’s SMC ring is essential for timely DNA replication and DNA loop formation

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1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.108999
  
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sciencedirect.com/science/article/pii/S2211124721003132
Mar 2021
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Systematic characterization of mutations altering protein degradation in human cancers

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1. scibot 29 Mar 2021
  
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  DOI: 10.1016/j.molcel.2021.01.020
  
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sciencedirect.com/science/article/pii/S109727652100040X
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MAT2A inhibition blocks the growth of MTAP-deleted cancer cells by reducing PRMT5-dependent mRNA splicing and inducing DNA damage

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1. scibot 01 Mar 2021
  
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  DOI: 10.1016/j.ccell.2020.12.010
  
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sciencedirect.com/science/article/pii/S1535610820306589
Feb 2021
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FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

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1. scibot 27 Feb 2021
  
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  DOI: 10.1016/j.cell.2020.11.042
  
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sciencedirect.com/science/article/pii/S0092867420316147
Jan 2020
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Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.06.043
  
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sciencedirect.com/science/article/pii/S2211124719308162
Nov 2018
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Untitled document

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S2211124718314086
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Genome-wide Control of Heterochromatin Replication by the Telomere Capping Protein TRF2

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1097276518302673
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Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1097276517308808
Nov 2017
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Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses

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1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S0092867417308796