326 Matching Annotations
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    The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex
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    ncbi.nlm.nih.gov/pmc/articles/PMC11021537/
  3. Apr 2024
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    Astrocyte-secreted neurocan controls inhibitory synapse formation and function
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    sciencedirect.com/science/article/pii/S0896627324001612
  5. Mar 2024
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    Two-photon live imaging of direct glia-to-neuron conversion in the mouse cortex
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    ncbi.nlm.nih.gov/pmc/articles/PMC10960291/
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    Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons
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    1. scibot 23 Mar 2024
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      DOI: 10.7554/eLife.92342

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    ncbi.nlm.nih.gov/pmc/articles/PMC10957175/
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    Impaired oxysterol-liver X receptor signaling underlies aberrant cortical neurogenesis in a stem cell model of neurodevelopmental disorder
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    sciencedirect.com/science/article/pii/S2211124724002742
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    An early cell shape transition drives evolutionary expansion of the human forebrain
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    sciencedirect.com/science/article/pii/S0092867421002397
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    Developmental and molecular contributions to contextual fear memory emergence in mice
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    nature.com/articles/s41386-024-01835-0
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    Quantifying differentiation of progenitor populations using cerebral organoid models for neurodevelopmental disorders
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    sciencedirect.com/science/article/pii/S2666166724000698
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    Neural and metabolic dysregulation in PMM2-deficient human in vitro neural models
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    sciencedirect.com/science/article/pii/S2211124724002110
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    Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression
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    sciencedirect.com/science/article/pii/S0896627324000898
  14. Feb 2024
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    ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells
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    1. scibot 29 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724001463
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    Loss of GTF2I promotes neuronal apoptosis and synaptic reduction in human cellular models of neurodevelopment
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    Modeling the precise interaction of glioblastoma with human brain region-specific organoids
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    ncbi.nlm.nih.gov/pmc/articles/PMC10882168/
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    Neonatal brain injury unravels transcriptional and signaling changes underlying the reactivation of cortical progenitors
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    1. scibot 18 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724000627
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    CSF1R-mediated myeloid cell depletion shifts the ratio of motor cortical excitatory to inhibitory neurons in a multiple system atrophy model
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    sciencedirect.com/science/article/pii/S0014488624000323
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    Long interspersed nuclear elements safeguard neural progenitors from precocious differentiation
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    sciencedirect.com/science/article/pii/S2211124724001025
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    Modulation of neuronal activity in cortical organoids with bioelectronic delivery of ions and neurotransmitters
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    1. scibot 03 Feb 2024
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      DOI: 10.1016/j.crmeth.2023.100686

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    ncbi.nlm.nih.gov/pmc/articles/PMC10831944/
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    3D bioprinting of human neural tissues with functional connectivity
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    sciencedirect.com/science/article/pii/S1934590923004393
  23. Jan 2024
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    Patterning ganglionic eminences in developing human brain organoids using a morphogen-gradient-inducing device
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      DOI: 10.1016/j.crmeth.2023.100689

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    sciencedirect.com/science/article/pii/S2667237523003752
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    SARS-CoV-2 infection causes dopaminergic neuron senescence
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    sciencedirect.com/science/article/pii/S1934590923004423
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    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
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    sciencedirect.com/science/article/pii/S0021925824000176
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Origin and development of the claustrum in rhesus macaque
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      DOI: 10.1073/pnas.2220918120

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    ncbi.nlm.nih.gov/pmc/articles/PMC10334778/
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    Human fetal brain self-organizes into long-term expanding organoids
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    sciencedirect.com/science/article/pii/S0092867423013442
  29. Dec 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Characterization of two human induced pluripotent stem cell lines derived from Batten disease patient fibroblasts harbouring CLN5 mutations
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    sciencedirect.com/science/article/pii/S1873506123002775
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    Repetitive CREB-DNA interactions at gene loci predetermined by CBP induce activity-dependent gene expression in human cortical neurons
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    sciencedirect.com/science/article/pii/S2211124723015887
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    FEZ1 participates in human embryonic brain development by modulating neuronal progenitor subpopulation specification and migration
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    sciencedirect.com/science/article/pii/S2589004223025749
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    Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala
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    sciencedirect.com/science/article/pii/S089662732300884X
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    Layer 6b controls brain state via apical dendrites and the higher-order thalamocortical system
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      DOI: 10.1016/j.neuron.2023.11.021

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    sciencedirect.com/science/article/pii/S0896627323008954
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neocortical neuronal production and maturation defects in the TcMAC21 mouse model of Down syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC10679816/
  36. Nov 2023
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    FMRP phosphorylation modulates neuronal translation through YTHDF1
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    sciencedirect.com/science/article/pii/S1097276523008651
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    Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities
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    sciencedirect.com/science/article/pii/S2211124723015085
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    Truncated radial glia as a common precursor in the late corticogenesis of gyrencephalic mammals
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      DOI: 10.7554/eLife.91406

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    ncbi.nlm.nih.gov/pmc/articles/PMC10662950/
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    Asymmetric inheritance of centrosomes maintains stem cell properties in human neural progenitor cells
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      DOI: 10.7554/eLife.83157

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    ncbi.nlm.nih.gov/pmc/articles/PMC10629821/
  41. Oct 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Single-cell long-read sequencing in human cerebral organoids uncovers cell-type-specific and autism-associated exons
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    sciencedirect.com/science/article/pii/S2211124723013475
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    A novel architecture of PT neuron-based corticothalamic connectivity in the auditory system
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    biorxiv.org/content/10.1101/2023.08.08.552413v2
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    Tissue morphology influences the temporal program of human brain organoid development
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    sciencedirect.com/science/article/pii/S1934590923003247
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model
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    ncbi.nlm.nih.gov/pmc/articles/PMC10521973/
  46. Sep 2023
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lmx1a is a master regulator of the cortical hem
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      DOI: 10.7554/eLife.84095

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    ncbi.nlm.nih.gov/pmc/articles/PMC10508884/
  48. Aug 2023
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    Neuronal miR-17-5p contributes to interhemispheric cortical connectivity defects induced by prenatal alcohol exposure
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    Protocol for generating in vitro glioma models using human-induced pluripotent- or embryonic-stem-cell-derived cerebral organoids
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    A Selective Projection from the Subthalamic Nucleus to Parvalbumin-Expressing Interneurons of the Striatum
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    Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice
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    Integrative systems biology characterizes immune-mediated neurodevelopmental changes in murine Zika Virus microcephaly
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  63. May 2023
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    Epistatic genetic interactions between Insm1 and Ikzf2 during cochlear outer hair cell development
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    Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex
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    Suppression of ferroptosis by vitamin A or antioxidants is essential for neuronal development
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    Large neutral amino acid levels tune perinatal neuronal excitability and survival
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    PQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation
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    Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations
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    The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool
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    Subcellular mRNA localization and local translation of Arhgap11a in radial glial progenitors regulates cortical development
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    Bulk and Mosaic Deletions of Egfr Reveal Regionally Defined Gliogenesis in the Developing Mouse Forebrain
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    Complement-dependent loss of inhibitory synapses on pyramidal neurons following Toxoplasma gondii infection
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    Neuronal activity-related transcription is blunted in immature compared to mature dentate granule cells
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    Natural variation in gene expression and viral susceptibility revealed by neural progenitor cell villages
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    Centrosomal microtubule nucleation regulates radial migration of projection neurons independently of polarization in the developing brain
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    Epitranscriptomic regulation of cortical neurogenesis via Mettl8-dependent mitochondrial tRNA m3C modification
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    Hippocampal-medial entorhinal circuit is differently organized along the dorsoventral axis in rodents
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    Reversibility and developmental neuropathology of linear nevus sebaceous syndrome caused by dysregulation of the RAS pathway
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    Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons
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  97. link.springer.com link.springer.com
    Laminar dynamics of deep projection neurons and mode of subplate formation are hallmarks of histogenetic subdivisions of the human cingulate cortex before onset of arealization
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  98. Dec 2022
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Temporal and sequential transcriptional dynamics define lineage shifts in corticogenesis
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    In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution
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    A critical period of translational control during brain development at codon resolution
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    A reference human induced pluripotent stem cell line for large-scale collaborative studies
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  103. Nov 2022
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    De-erosion of X chromosome dosage compensation by the editing of XIST regulatory regions restores the differentiation potential in hPSCs
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    Gabrb3 is required for the functional integration of pyramidal neuron subtypes in the somatosensory cortex
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    Spread of pathological human Tau from neurons to oligodendrocytes and loss of high-firing pyramidal neurons in aging mice
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  109. Oct 2022
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    Retrosplenial and subicular inputs converge on superficially projecting layer V neurons of medial entorhinal cortex
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    Loss of non-motor kinesin KIF26A causes congenital brain malformations via dysregulated neuronal migration and axonal growth as well as apoptosis
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    Subclass-specific expression patterns of MET receptor tyrosine kinase during development in medial prefrontal and visual cortices
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    Human PSCs determine the competency of cerebral organoid differentiation via FGF signaling and epigenetic mechanisms
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  117. Sep 2022
  118. www.sciencedirect.com www.sciencedirect.com
    Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain
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    Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex
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    Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development
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    Human-specific ARHGAP11B ensures human-like basal progenitor levels in hominid cerebral organoids
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    A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer
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  123. elifesciences.org elifesciences.org
    Molecular characteristics and laminar distribution of prefrontal neurons projecting to the mesolimbic system
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  124. Aug 2022
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    m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs
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    A microcarrier-based protocol for scalable generation and purification of human induced pluripotent stem cell-derived neurons and astrocytes
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    Features of the Development of the Human Cerebral Cortex during the Second Trimester of Gestation
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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway
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  129. Jul 2022
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    Ubiquitination and deubiquitination of 4E-T regulate neural progenitor cell maintenance and neurogenesis by controlling P-body formation
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    Tbr1 Misexpression Alters Neuronal Development in the Cerebral Cortex
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  132. Jun 2022
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    3D imaging of supraspinal inputs to the thoracic and lumbar spinal cord mapped by retrograde tracing and light-sheet microscopy
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    A systematic characterization of microglia-like cell occurrence during retinal organoid differentiation.
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  135. May 2022
  136. www.sciencedirect.com www.sciencedirect.com
    Regionally defined proteomic profiles of human cerebral tissue and organoids reveal conserved molecular modules of neurodevelopment
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    The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth
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    The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling
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  139. Apr 2022
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    CHD8 haploinsufficiency links autism to transient alterations in excitatory and inhibitory trajectories
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperoxygenation During Mid-Neurogenesis Accelerates Cortical Development in the Fetal Mouse Brain
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  143. Mar 2022
  144. www.sciencedirect.com www.sciencedirect.com
    Orientation and direction tuning align with dendritic morphology and spatial connectivity in mouse visual cortex
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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mapping Motor Neuron Vulnerability in the Neuraxis of Male SOD1G93A Mice Reveals Widespread Loss of Androgen Receptor Occurring Early in Spinal Motor Neurons
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  146. Feb 2022
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    Developmental defects in Huntington’s disease show that axonal growth and microtubule reorganization require NUMA1
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    The distribution of Cdh20 mRNA demarcates somatotopic subregions and subpopulations of spiny projection neurons in the rat dorsolateral striatum
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    ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids
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    A Translational Repression Complex in Developing Mammalian Neural Stem Cells that Regulates Neuronal Specification
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    The 7q11.23 Protein DNAJC30 Interacts with ATP Synthase and Links Mitochondria to Brain Development
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    Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140
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    Lengthening Neurogenic Period during Neocortical Development Causes a Hallmark of Neocortex Expansion
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    Diversity in striatal synaptic circuits arises from distinct embryonic progenitor pools in the ventral telencephalon
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    Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia
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