356 Matching Annotations
  1. Oct 2024
  2. www.nature.com www.nature.com
    Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids
    1
    1. scibot 04 Oct 2024
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      DOI: 10.1038/s41380-024-02761-9

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    nature.com/articles/s41380-024-02761-9
  3. Sep 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.neuron.2019.03.036

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    sciencedirect.com/science/article/pii/S0896627319302995
  5. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Reproducible Differentiation of Human Pluripotent Stem Cells into Two-Dimensional Cortical Neuron Cultures with Checkpoints for Success
    1
    1. scibot 13 Sep 2024
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      DOI: 10.1002/cpz1.948

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    currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.948
  6. www.sciencedirect.com www.sciencedirect.com
    Metformin decelerates aging clock in male monkeys
    1
    1. scibot 13 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.021

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    sciencedirect.com/science/article/pii/S0092867424009140
  7. www.sciencedirect.com www.sciencedirect.com
    Fully defined NGN2 neuron protocol reveals diverse signatures of neuronal maturation
    1
    1. scibot 10 Sep 2024
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    sciencedirect.com/science/article/pii/S2667237524002364
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes
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      DOI: 10.1038/s41467-024-51676-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC11362472/
  9. Aug 2024
  10. www.sciencedirect.com www.sciencedirect.com
    A single-cell transcriptomic census of mammalian olfactory epithelium aging
    1
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      DOI: 10.1016/j.devcel.2024.07.020

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    sciencedirect.com/science/article/pii/S1534580724004829
  11. www.sciencedirect.com www.sciencedirect.com
    BEAM: A combinatorial recombinase toolbox for binary gene expression and mosaic genetic analysis
    1
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    sciencedirect.com/science/article/pii/S2211124724010015
  12. www.cell.com www.cell.com
    Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity
    1
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      DOI: 10.1016/s0896-6273(00)81251-9

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    cell.com/neuron/pdfExtended/S0896-6273(16)30203-3
  13. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Developmental and adult expression patterns of the G‐protein‐coupled receptor GPR88 in the rat: Establishment of a dual nuclear–cytoplasmic localization
    2
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      DOI: 10.1002/cne.23991

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      AB_2064130

      DOI: 10.1002/cne.23991

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    onlinelibrary.wiley.com/doi/10.1002/cne.23991/full
  14. Local file Local file
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    1. scibot 02 Aug 2024
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  15. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fezf2 expression in layer 5 projection neurons of mature mouse motor cortex
    2
    1. scibot 02 Aug 2024
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      DOI: 10.1002/cne.23875

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      AB_2064130

      DOI: 10.1002/cne.23875

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    onlinelibrary.wiley.com/doi/10.1002/cne.23875/full
  16. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Altered proliferative ability of neuronal progenitors in PlexinA1 mutant mice
    1
    1. scibot 02 Aug 2024
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      DOI: 10.1002/cne.23806

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    onlinelibrary.wiley.com/doi/10.1002/cne.23806/full
  17. Jul 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions
    1
    1. scibot 30 Jul 2024
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      DOI: 10.1016/j.neuron.2024.06.002

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    ncbi.nlm.nih.gov/pmc/articles/PMC11377155/
  19. www.cell.com www.cell.com
    Dynamic regulation of alternative polyadenylation by PQBP1 during neurogenesis
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114525

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    cell.com/cell-reports/abstract/S2211-1247(24)00854-4
  20. www.sciencedirect.com www.sciencedirect.com
    A hominoid-specific signaling axis regulating the tempo of synaptic maturation
    1
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    sciencedirect.com/science/article/pii/S2211124724008775
  21. www.sciencedirect.com www.sciencedirect.com
    Impaired phase separation and nucleolar functions in hiPSC models of SNORD118-related ribosomopathies
    1
    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.isci.2024.110430

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    sciencedirect.com/science/article/pii/S2589004224016559
  22. www.sciencedirect.com www.sciencedirect.com
    Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus
    1
    1. scibot 17 Jul 2024
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      DOI: 10.1016/j.xcrm.2024.101647

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    sciencedirect.com/science/article/pii/S2666379124003616
  23. www.sciencedirect.com www.sciencedirect.com
    DCX knockout ferret reveals a neurogenic mechanism in cortical development
    1
    1. scibot 17 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114508

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    sciencedirect.com/science/article/pii/S2211124724008374
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment of human cerebral organoid systems to model early neural development and assess the central neurotoxicity of environmental toxins
    1
    1. scibot 17 Jul 2024
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      DOI: 10.4103/NRR.NRR-D-23-00928

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    ncbi.nlm.nih.gov/pmc/articles/PMC11246146/
  25. www.sciencedirect.com www.sciencedirect.com
    Cell-type-specific loops linked to RNA polymerase II elongation in human neural differentiation
    1
    1. scibot 11 Jul 2024
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      DOI: 10.1016/j.xgen.2024.100606

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    sciencedirect.com/science/article/pii/S2666979X24002003
  26. Jun 2024
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inflammatory Response and Defects on Myelin Integrity in the Olfactory System of K18hACE2 Mice Infected with SARS-CoV-2
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    1. scibot 22 Jun 2024
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      DOI: 10.1523/ENEURO.0106-24.2024

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    ncbi.nlm.nih.gov/pmc/articles/PMC11185043/
  28. May 2024
  29. www.sciencedirect.com www.sciencedirect.com
    Srcap haploinsufficiency induced autistic-like behaviors in mice through disruption of Satb2 expression
    1
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    sciencedirect.com/science/article/pii/S221112472400559X
  30. www.sciencedirect.com www.sciencedirect.com
    Effective cryopreservation of human brain tissue and neural organoids
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      DOI: 10.1016/j.crmeth.2024.100777

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    sciencedirect.com/science/article/pii/S2667237524001218
  31. www.sciencedirect.com www.sciencedirect.com
    ARID1B controls transcriptional programs of axon projection in an organoid model of the human corpus callosum
    1
    1. scibot 08 May 2024
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      DOI: 10.1016/j.stem.2024.04.014

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    sciencedirect.com/science/article/pii/S1934590924001413
  32. www.sciencedirect.com www.sciencedirect.com
    Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size
    1
    1. scibot 02 May 2024
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      DOI: 10.1016/j.neuron.2024.04.006

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    sciencedirect.com/science/article/pii/S0896627324002447
  33. Apr 2024
  34. www.embopress.org www.embopress.org
    The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex
    2
    1. scibot 25 Apr 2024
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      DOI: 10.1038/s44318-024-00068-7

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      DOI: 10.1038/s44318-024-00068-7

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    embopress.org/doi/full/10.1038/s44318-024-00068-7
  35. www.embopress.org www.embopress.org
    The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex
    1
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      DOI: 10.1038/s44318-024-00068-7

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    embopress.org/doi/10.1038/s44318-024-00068-7
  36. www.cell.com www.cell.com
    Astrocyte-secreted neurocan controls inhibitory synapse formation and function
    1
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    cell.com/neuron/fulltext/S0896-6273(24)00161-2
  37. Mar 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two-photon live imaging of direct glia-to-neuron conversion in the mouse cortex
    1
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      DOI: 10.4103/1673-5374.386401

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    ncbi.nlm.nih.gov/pmc/articles/PMC10960291/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons
    1
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      DOI: 10.7554/eLife.92342

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    ncbi.nlm.nih.gov/pmc/articles/PMC10957175/
  40. www.sciencedirect.com www.sciencedirect.com
    Impaired oxysterol-liver X receptor signaling underlies aberrant cortical neurogenesis in a stem cell model of neurodevelopmental disorder
    2
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    sciencedirect.com/science/article/pii/S2211124724002742
  41. www.sciencedirect.com www.sciencedirect.com
    An early cell shape transition drives evolutionary expansion of the human forebrain
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      DOI: 10.1016/j.cell.2021.02.050

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    sciencedirect.com/science/article/pii/S0092867421002397
  42. www.nature.com www.nature.com
    Developmental and molecular contributions to contextual fear memory emergence in mice
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      DOI: 10.1038/s41386-024-01835-0

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    nature.com/articles/s41386-024-01835-0
  43. www.sciencedirect.com www.sciencedirect.com
    Quantifying differentiation of progenitor populations using cerebral organoid models for neurodevelopmental disorders
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      DOI: 10.1016/j.xpro.2024.102904

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    sciencedirect.com/science/article/pii/S2666166724000698
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    Neural and metabolic dysregulation in PMM2-deficient human in vitro neural models
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      DOI: 10.1016/j.celrep.2024.113883

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    sciencedirect.com/science/article/pii/S2211124724002110
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    Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression
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      DOI: 10.1016/j.neuron.2024.02.005

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    sciencedirect.com/science/article/pii/S0896627324000898
  46. Feb 2024
  47. www.sciencedirect.com www.sciencedirect.com
    ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells
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    Loss of GTF2I promotes neuronal apoptosis and synaptic reduction in human cellular models of neurodevelopment
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    Neonatal brain injury unravels transcriptional and signaling changes underlying the reactivation of cortical progenitors
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    CSF1R-mediated myeloid cell depletion shifts the ratio of motor cortical excitatory to inhibitory neurons in a multiple system atrophy model
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    Long interspersed nuclear elements safeguard neural progenitors from precocious differentiation
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    Modulation of neuronal activity in cortical organoids with bioelectronic delivery of ions and neurotransmitters
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  55. Jan 2024
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    Patterning ganglionic eminences in developing human brain organoids using a morphogen-gradient-inducing device
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    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
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  61. Dec 2023
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    Characterization of two human induced pluripotent stem cell lines derived from Batten disease patient fibroblasts harbouring CLN5 mutations
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    Repetitive CREB-DNA interactions at gene loci predetermined by CBP induce activity-dependent gene expression in human cortical neurons
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    FEZ1 participates in human embryonic brain development by modulating neuronal progenitor subpopulation specification and migration
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    Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala
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    Layer 6b controls brain state via apical dendrites and the higher-order thalamocortical system
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    Neocortical neuronal production and maturation defects in the TcMAC21 mouse model of Down syndrome
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  68. Nov 2023
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    FMRP phosphorylation modulates neuronal translation through YTHDF1
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    Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities
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    Truncated radial glia as a common precursor in the late corticogenesis of gyrencephalic mammals
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    Asymmetric inheritance of centrosomes maintains stem cell properties in human neural progenitor cells
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  73. Oct 2023
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    Single-cell long-read sequencing in human cerebral organoids uncovers cell-type-specific and autism-associated exons
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    A novel architecture of PT neuron-based corticothalamic connectivity in the auditory system
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    Tissue morphology influences the temporal program of human brain organoid development
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    PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model
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    Neuronal miR-17-5p contributes to interhemispheric cortical connectivity defects induced by prenatal alcohol exposure
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    Protocol for generating in vitro glioma models using human-induced pluripotent- or embryonic-stem-cell-derived cerebral organoids
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    A Selective Projection from the Subthalamic Nucleus to Parvalbumin-Expressing Interneurons of the Striatum
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  85. Jun 2023
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    Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice
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    Dissection of insular cortex layer 5 reveals two sublayers with opposing modulatory roles in appetitive drinking behavior
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    SRSF10 regulates proliferation of neural progenitor cells and affects neurogenesis in developing mouse neocortex
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    Ccdc85c-Par3 condensates couple cell polarity with Notch to control neural progenitor proliferation
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    Direct and indirect neurogenesis generate a mosaic of distinct glutamatergic projection neuron types in cerebral cortex
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    Integrative systems biology characterizes immune-mediated neurodevelopmental changes in murine Zika Virus microcephaly
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    Differentiation, Transcriptomic Profiling, and Calcium Imaging of Human Hypothalamic Neurons
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    A unique role for Protocadherin γC3 in promoting dendrite arborization through an Axin1-dependent mechanism
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  95. May 2023
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    Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex
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    The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool
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    Subcellular mRNA localization and local translation of Arhgap11a in radial glial progenitors regulates cortical development
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    Bulk and Mosaic Deletions of Egfr Reveal Regionally Defined Gliogenesis in the Developing Mouse Forebrain
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    Centrosomal microtubule nucleation regulates radial migration of projection neurons independently of polarization in the developing brain
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    Hippocampal-medial entorhinal circuit is differently organized along the dorsoventral axis in rodents
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    Reversibility and developmental neuropathology of linear nevus sebaceous syndrome caused by dysregulation of the RAS pathway
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    Laminar dynamics of deep projection neurons and mode of subplate formation are hallmarks of histogenetic subdivisions of the human cingulate cortex before onset of arealization
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    In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution
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    A reference human induced pluripotent stem cell line for large-scale collaborative studies
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    De-erosion of X chromosome dosage compensation by the editing of XIST regulatory regions restores the differentiation potential in hPSCs
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    Gabrb3 is required for the functional integration of pyramidal neuron subtypes in the somatosensory cortex
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    Reelin regulates the migration of late-born hippocampal CA1 neurons via cofilin phosphorylation
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    Spread of pathological human Tau from neurons to oligodendrocytes and loss of high-firing pyramidal neurons in aging mice
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  141. Oct 2022
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  143. www.jneurosci.org www.jneurosci.org
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    Retrosplenial and subicular inputs converge on superficially projecting layer V neurons of medial entorhinal cortex
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    Loss of non-motor kinesin KIF26A causes congenital brain malformations via dysregulated neuronal migration and axonal growth as well as apoptosis
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    Human-specific regulation of neural maturation identified by cross-primate transcriptomics
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  147. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Subclass-specific expression patterns of MET receptor tyrosine kinase during development in medial prefrontal and visual cortices
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human PSCs determine the competency of cerebral organoid differentiation via FGF signaling and epigenetic mechanisms
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  149. Sep 2022
  150. www.sciencedirect.com www.sciencedirect.com
    Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain
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    Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex
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    Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development
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    Human-specific ARHGAP11B ensures human-like basal progenitor levels in hominid cerebral organoids
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    A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer
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  155. elifesciences.org elifesciences.org
    Molecular characteristics and laminar distribution of prefrontal neurons projecting to the mesolimbic system
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  156. Aug 2022
  157. www.sciencedirect.com www.sciencedirect.com
    m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs
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    A microcarrier-based protocol for scalable generation and purification of human induced pluripotent stem cell-derived neurons and astrocytes
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  159. 52.53.155.43 52.53.155.43
    Features of the Development of the Human Cerebral Cortex during the Second Trimester of Gestation
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  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway
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  161. Jul 2022
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    Ubiquitination and deubiquitination of 4E-T regulate neural progenitor cell maintenance and neurogenesis by controlling P-body formation
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  163. link.springer.com link.springer.com
    Tbr1 Misexpression Alters Neuronal Development in the Cerebral Cortex
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  164. Jun 2022
  165. onlinelibrary.wiley.com onlinelibrary.wiley.com
    3D imaging of supraspinal inputs to the thoracic and lumbar spinal cord mapped by retrograde tracing and light-sheet microscopy
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    A systematic characterization of microglia-like cell occurrence during retinal organoid differentiation.
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  167. May 2022
  168. www.sciencedirect.com www.sciencedirect.com
    Regionally defined proteomic profiles of human cerebral tissue and organoids reveal conserved molecular modules of neurodevelopment
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    The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth
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    The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling
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  171. Apr 2022
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    CHD8 haploinsufficiency links autism to transient alterations in excitatory and inhibitory trajectories
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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperoxygenation During Mid-Neurogenesis Accelerates Cortical Development in the Fetal Mouse Brain
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  175. Mar 2022
  176. www.sciencedirect.com www.sciencedirect.com
    Orientation and direction tuning align with dendritic morphology and spatial connectivity in mouse visual cortex
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  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mapping Motor Neuron Vulnerability in the Neuraxis of Male SOD1G93A Mice Reveals Widespread Loss of Androgen Receptor Occurring Early in Spinal Motor Neurons
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  178. Feb 2022
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    Characterization of the neurogenic niche in the aging dentate gyrus using iterative immunofluorescence imaging
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  180. Jan 2022
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    Uncovering specificity of endogenous TAU aggregation in a human iPSC-neuron TAU seeding model
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  182. Dec 2021
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  184. Nov 2021
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    Developmental defects in Huntington’s disease show that axonal growth and microtubule reorganization require NUMA1
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  186. Oct 2021
  187. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Characterization and manipulation of Corticothalamic neurons in associative cortices using Syt6-Cre transgenic mice
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  189. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transient expansion of the expression region of Hsd11b1, encoding 11β-hydroxysteroid dehydrogenase type 1, in the developing mouse neocortex
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    Akt regulates Sox10 expression to control oligodendrocyte differentiation via phosphorylating FoxO1
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    Restoration of the defect in radial glial fiber migration and cortical plate organization in a brain organoid model of Fukuyama muscular dystrophy
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    A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation
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    FLRT2 and FLRT3 cooperate in maintaining the tangential migratory streams of cortical interneurons during development
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