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  1. Last 7 days
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    Therapy-induced DNA methylation inactivates MCT1 and renders tumor cells vulnerable to MCT4 inhibition
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    sciencedirect.com/science/article/pii/S2211124721005519
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    Acetyl-CoA metabolism maintains histone acetylation for syncytialization of human placental trophoblast stem cells
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    sciencedirect.com/science/article/pii/S1934590924002534
  4. May 2024
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    Distinctive multicellular immunosuppressive hubs confer different intervention strategies for left- and right-sided colon cancers
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    sciencedirect.com/science/article/pii/S2666379124002817
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16420
  7. Feb 2024
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    Loss of mitochondrial pyruvate carrier 1 supports proline-dependent proliferation and collagen biosynthesis in ovarian cancer
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    sciencedirect.com/science/article/pii/S2212877824000310
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    Palmitoylation alters LDHA activity and pancreatic cancer response to chemotherapy
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    sciencedirect.com/science/article/abs/pii/S0304383524000892
  10. Jan 2024
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    Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling
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    sciencedirect.com/science/article/pii/S2211124724000160
  12. Oct 2023
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    STAT3 modulates CD4+ T mitochondrial dynamics and function in aging
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    onlinelibrary.wiley.com/doi/10.1111/acel.13996
  14. Aug 2023
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    Ets1 facilitates EMT/invasion through Drp1-mediated mitochondrial fragmentation in ovarian cancer
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    sciencedirect.com/science/article/pii/S2589004223016140
  16. Feb 2023
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    Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation
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  18. Nov 2022
  19. 52.53.155.43 52.53.155.43
    Lactate as a major epigenetic carbon source for histone acetylation via nuclear LDH metabolism
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    Ultrasensitive sensors reveal the spatiotemporal landscape of lactate metabolism in physiology and disease
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    sciencedirect.com/science/article/pii/S1550413122004533
  21. Jun 2022
  22. 52.53.155.43 52.53.155.43
    cd-21-1022-html.html
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    1. scibot 30 Jun 2022
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    52.53.155.43/dae3a722cb0f412060233d3b16799226aa47507e/cd-21-1022-html.html
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    Influence of maternal exercise on glucose and lipid metabolism in offspring stem cells: ENHANCED by Mom
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      DOI: 10.1210/clinem/dgac270

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac270/6577152
  24. Mar 2022
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    Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist
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    ncbi.nlm.nih.gov/pmc/articles/PMC8901637/
  26. Feb 2022
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    Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments
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    sciencedirect.com/science/article/pii/S1535610822000034
  28. Jan 2022
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    Metabolic diversity within breast cancer brain-tropic cells determines metastatic fitness
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    sciencedirect.com/science/article/pii/S1550413121006203
  30. Nov 2021
  31. cancerci.biomedcentral.com cancerci.biomedcentral.com
    Starvation induced autophagy promotes the progression of bladder cancer by LDHA mediated metabolic reprogramming
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    cancerci.biomedcentral.com/articles/10.1186/s12935-021-02303-1
  32. Aug 2021
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    Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE
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    sciencedirect.com/science/article/pii/S0092867421008801
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    ncbi.nlm.nih.gov/pmc/articles/PMC5684706/
  36. Apr 2021
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    Local production of lactate, ribose phosphate, and amino acids by human triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2666634021001112
  38. Feb 2021
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    Isotope tracing reveals glycolysis and oxidative metabolism in childhood tumors of multiple histologies
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  40. Sep 2020
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    Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer
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    sciencedirect.com/science/article/pii/S153561082030427X
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    Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation
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    sciencedirect.com/science/article/pii/S1550413120301972
  43. Jan 2020
  44. www.nature.com www.nature.com
    eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma
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      DOI: 10.1038/s41467-019-13086-5

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    nature.com/articles/s41467-019-13086-5
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    The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase
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      DOI: 10.1016/j.cell.2019.07.031

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    sciencedirect.com/science/article/pii/S009286741930830X
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    Non-enzymatic Lysine Lactoylation of Glycolytic Enzymes
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      DOI: 10.1016/j.chembiol.2019.11.005

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    sciencedirect.com/science/article/pii/S2451945619303630
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6484776/
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      DOI: 10.1016/j.chom.2019.02.015

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    sciencedirect.com/science/article/pii/S1931312819301118
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      DOI: 10.1016/j.devcel.2019.03.011

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    sciencedirect.com/science/article/pii/S1534580719301881
  50. Nov 2018
  51. www.sciencedirect.com www.sciencedirect.com
    Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization
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    sciencedirect.com/science/article/pii/S009286741831033X
  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14264
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC5926201/
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    Lactate Metabolism in Human Lung Tumors
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    sciencedirect.com/science/article/pii/S0092867417310681
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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    sciencedirect.com/science/article/pii/S1550413117306186
  56. Nov 2017
  57. www.sciencedirect.com www.sciencedirect.com
    MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer
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      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1535610817302544