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PRC1 promotes MAFLD progression by regulating glycolysis/lactylation axis and forming a positive feedback loop

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1. scibot 15 Apr 2026
  
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  DOI: 10.1016/j.jnutbio.2026.110378
  
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sciencedirect.com/science/article/pii/S0955286326001208
Mar 2026
54.241.53.176 54.241.53.176

1-s2.0-S2589004226006206-main-html.html

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1. scibot 06 Mar 2026
  
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54.241.53.176/e71a465570120b1dc1df75cd20cf6d041cd0ae6c/1-s2.0-S2589004226006206-main-html.html
Feb 2026
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1-s2.0-S2589004226004827-main-html.html

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1. scibot 24 Feb 2026
  
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  DOI: 10.1016/j.isci.2026.115107
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12972699/
Dec 2025
54.241.53.176 54.241.53.176

2025.12.02.691634.full-html.html

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1. scibot 16 Dec 2025
  
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  DOI: 10.64898/2025.12.02.691634
  
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54.241.53.176/198fbbce9f086ab5db289a9a142f3485c6314e0b/2025.12.02.691634.full-html.html
Sep 2025
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liu-et-al-2025-cdk1-mediated-phosphorylation-of-ldha-fuels-mitosis-through-ldhb-dependent-lactate-oxidation-html.html

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1. scibot 16 Sep 2025
  
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  DOI: 10.1038/s44319-025-00573-8
  
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52.53.155.43/8969937eef43abf2851dde2e85f0dd07c6ffdab0/liu-et-al-2025-cdk1-mediated-phosphorylation-of-ldha-fuels-mitosis-through-ldhb-dependent-lactate-oxidation-html.html
Jul 2025
www.science.org www.science.org

Direct sensing of dietary ω-6 linoleic acid through FABP5-mTORC1 signaling

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1. scibot 25 Jul 2025
  
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  DOI: 10.1126/science.adm9805
  
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science.org/doi/10.1126/science.adm9805
Jun 2025
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Synergistic targeting of cancer cells through simultaneous inhibition of key metabolic enzymes

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1. scibot 24 Jun 2025
  
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  DOI: 10.1038/s41418-025-01532-5
  
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nature.com/articles/s41418-025-01532-5
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PRPS activity tunes redox homeostasis in Myc-driven lymphoma

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1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.redox.2025.103649
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12166406/
May 2025
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Indole-3-lactic acid suppresses colorectal cancer via metabolic reprogramming

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1. scibot 31 May 2025
  
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  DOI: 10.1080/19490976.2025.2508949
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12118437/
Mar 2025
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Hypoxia inducible factor-1α drives cancer resistance to cuproptosis

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1. scibot 07 Mar 2025
  
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  DOI: 10.1016/j.ccell.2025.02.015
  
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sciencedirect.com/science/article/pii/S1535610825000674
Feb 2025
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Interferon-a potentiates anti-PD-1 efficacy by remodeling glucose metabolism in the hepatocellular carcinoma microenvironment

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1. scibot 14 Feb 2025
  
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  DOI: 10.1158/2159-8290.CD-21-1022
  
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aacrjournals.org/cancerdiscovery/article/12/7/1718/705192/IFN-Potentiates-Anti-PD-1-Efficacy-by-Remodeling
Nov 2024
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ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

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1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.cmet.2024.10.015
  
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sciencedirect.com/science/article/pii/S155041312400411X
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Deciphering the Metabolic Basis and Molecular Circuitry of the Warburg Paradox in Lymphoma

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1. scibot 14 Nov 2024
  
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  DOI: 10.3390/cancers16213606
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11545614/
Oct 2024
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Local glycolysis supports injury-induced axonal regeneration

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1. scibot 08 Oct 2024
  
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  DOI: 10.1083/jcb.202402133
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11451009/
Aug 2024
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CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

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1. scibot 21 Aug 2024
  
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  RRID:AB_2066887
  
  DOI: 10.1016/j.cmet.2017.10.006
  
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sciencedirect.com/science/article/pii/S1550413117306186
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Therapy-induced DNA methylation inactivates MCT1 and renders tumor cells vulnerable to MCT4 inhibition

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1. scibot 02 Aug 2024
  
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  DOI: 10.1016/j.celrep.2021.109202
  
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sciencedirect.com/science/article/pii/S2211124721005519
Jul 2024
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Acetyl-CoA metabolism maintains histone acetylation for syncytialization of human placental trophoblast stem cells

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1. scibot 31 Jul 2024
  
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  DOI: 10.1016/j.stem.2024.07.003
  
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sciencedirect.com/science/article/pii/S1934590924002534
May 2024
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Distinctive multicellular immunosuppressive hubs confer different intervention strategies for left- and right-sided colon cancers

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1. scibot 30 May 2024
  
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  RRID:AB_2066887
  
  DOI: 10.1016/j.xcrm.2024.101589
  
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sciencedirect.com/science/article/pii/S2666379124002817
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BPS Publications

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1. scibot 30 May 2024
  
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  RRID:AB_2066887
  
  DOI: 10.1111/bph.16420
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16420
Feb 2024
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Loss of mitochondrial pyruvate carrier 1 supports proline-dependent proliferation and collagen biosynthesis in ovarian cancer

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1. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.molmet.2024.101900
  
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sciencedirect.com/science/article/pii/S2212877824000310
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Palmitoylation alters LDHA activity and pancreatic cancer response to chemotherapy

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1. scibot 08 Feb 2024
  
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  DOI: 10.1016/j.canlet.2024.216696
  
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sciencedirect.com/science/article/abs/pii/S0304383524000892
Jan 2024
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Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling

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1. scibot 20 Jan 2024
  
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  DOI: 10.1016/j.celrep.2024.113688
  
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sciencedirect.com/science/article/pii/S2211124724000160
Oct 2023
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STAT3 modulates CD4+ T mitochondrial dynamics and function in aging

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1. scibot 17 Oct 2023
  
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  DOI: 10.1111/acel.13996
  
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onlinelibrary.wiley.com/doi/10.1111/acel.13996
Aug 2023
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Ets1 facilitates EMT/invasion through Drp1-mediated mitochondrial fragmentation in ovarian cancer

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1. scibot 23 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107537
  
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sciencedirect.com/science/article/pii/S2589004223016140
Feb 2023
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Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation

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  DOI: 10.1016/j.celrep.2023.112033
  
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sciencedirect.com/science/article/pii/S221112472300044X
Nov 2022
52.53.155.43 52.53.155.43

Lactate as a major epigenetic carbon source for histone acetylation via nuclear LDH metabolism

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1. scibot 03 Nov 2022
  
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  DOI: 10.21203/rs.3.rs-1698453/v1
  
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  DOI: 10.21203/rs.3.rs-1698453/v1
  
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52.53.155.43/a9aa811c4130566b40962c2f0a83959683ec478d/49f9f782-b71a-4af1-934b-03c6d94197f9-html.html
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Ultrasensitive sensors reveal the spatiotemporal landscape of lactate metabolism in physiology and disease

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  DOI: 10.1016/j.cmet.2022.10.002
  
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sciencedirect.com/science/article/pii/S1550413122004533
Jun 2022
52.53.155.43 52.53.155.43

cd-21-1022-html.html

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1. scibot 30 Jun 2022
  
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  DOI: 10.1158/2159-8290.CD-21-1022
  
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  DOI: 10.1158/2159-8290.cd-21-1022
  
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  DOI: 10.1158/2159-8290.cd-21-1022
  
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52.53.155.43/dae3a722cb0f412060233d3b16799226aa47507e/cd-21-1022-html.html
academic.oup.com academic.oup.com

Influence of maternal exercise on glucose and lipid metabolism in offspring stem cells: ENHANCED by Mom

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1. scibot 03 Jun 2022
  
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  DOI: 10.1210/clinem/dgac270
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac270/6577152
Mar 2022
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Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist

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1. scibot 11 Mar 2022
  
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  DOI: 10.1038/s41598-022-07600-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8901637/
Feb 2022
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Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

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1. scibot 02 Feb 2022
  
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  DOI: 10.1016/j.ccell.2022.01.001
  
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sciencedirect.com/science/article/pii/S1535610822000034
Jan 2022
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Metabolic diversity within breast cancer brain-tropic cells determines metastatic fitness

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1. scibot 05 Jan 2022
  
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  DOI: 10.1016/j.cmet.2021.12.001
  
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sciencedirect.com/science/article/pii/S1550413121006203
Nov 2021
cancerci.biomedcentral.com cancerci.biomedcentral.com

Starvation induced autophagy promotes the progression of bladder cancer by LDHA mediated metabolic reprogramming

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1. scibot 09 Nov 2021
  
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  DOI: 10.1186/s12935-021-02303-1
  
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cancerci.biomedcentral.com/articles/10.1186/s12935-021-02303-1
Aug 2021
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Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE

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  DOI: 10.1016/j.cell.2021.07.021
  
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  DOI: 10.1016/j.cell.2017.09.019
  
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Apr 2021
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Local production of lactate, ribose phosphate, and amino acids by human triple-negative breast cancer

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  DOI: 10.1016/j.medj.2021.03.009
  
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Feb 2021
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Isotope tracing reveals glycolysis and oxidative metabolism in childhood tumors of multiple histologies

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Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer

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Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation

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eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

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  DOI: 10.1038/s41467-019-13086-5
  
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The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase

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Non-enzymatic Lysine Lactoylation of Glycolytic Enzymes

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  DOI: 10.1016/j.chembiol.2019.11.005
  
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  DOI: 10.1016/j.devcel.2019.03.011
  
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Nov 2018
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Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization

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Systematic Functional Annotation of Somatic Mutations in Cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC5926201/
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Lactate Metabolism in Human Lung Tumors

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CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

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sciencedirect.com/science/article/pii/S1550413117306186
Nov 2017
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MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer

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