30 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    A senescence restriction point acting on chromatin integrates oncogenic signals
    1
    1. scibot 04 Apr 2024
      RRID:AB_2067317

      DOI: 10.1016/j.celrep.2024.114044

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    sciencedirect.com/science/article/pii/S2211124724003723
  3. Mar 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The effects of Aurora Kinase inhibition on thyroid cancer growth and sensitivity to MAPK-directed therapies
    1
    1. scibot 27 Mar 2024
      RRID:AB_2067317

      DOI: 10.1080/15384047.2024.2332000

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    ncbi.nlm.nih.gov/pmc/articles/PMC10962586/
  5. Sep 2023
  6. www.sciencedirect.com www.sciencedirect.com
    MAPK-ERK-CREB signaling pathway upregulates Nav1.6 in oxaliplatin-induced neuropathic pain in the rat
    1
    1. scibot 29 Sep 2023
      RRID:AB_2067317

      DOI: 10.1016/j.toxlet.2023.07.010

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    sciencedirect.com/science/article/pii/S0378427423002254
  7. Jun 2023
  8. www.science.org www.science.org
    HPIP is an essential scaffolding protein running through the EGFR-RAS-ERK pathway and drives tumorigenesis
    2
    1. scibot 16 Jun 2023
      RRID:AB_2067317

      DOI: 10.1126/sciadv.ade1155

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    2. scibot 12 Jun 2023
      RRID:AB_2067317

      DOI: 10.1126/sciadv.ade1155

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      Curator: @olekpark

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    science.org/doi/10.1126/sciadv.ade1155
  9. Apr 2023
  10. www.embopress.org www.embopress.org
    RAF1 deficiency causes a lethal syndrome that underscores RTK signaling during embryogenesis
    1
    1. scibot 18 Apr 2023
      RRID:AB_2067317

      DOI: 10.15252/emmm.202217078

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    embopress.org/doi/10.15252/emmm.202217078
  11. Jan 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma
    1
    1. scibot 10 Jan 2023
      RRID:AB_2067317

      DOI: 10.1016/j.immuni.2022.11.014

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    sciencedirect.com/science/article/pii/S1074761322006045
  13. Dec 2022
  14. link.springer.com link.springer.com
    The Agonist of Adenosine A1 Receptor Induced Desensitization of delta Opioid receptor-mediated Raf-1/MEK/ERK Signaling by Feedback Phosphorylation of Raf-1-Ser289/296/301
    1
    1. scibot 17 Dec 2022
      RRID:AB_2067317

      DOI: 10.1007/s11064-022-03843-2

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    link.springer.com/article/10.1007/s11064-022-03843-2
  15. Sep 2022
  16. www.sciencedirect.com www.sciencedirect.com
    A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration
    1
    1. scibot 29 Sep 2022
      RRID:AB_2067317

      DOI: 10.1016/j.devcel.2022.09.003

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    sciencedirect.com/science/article/pii/S1534580722006335
  17. Apr 2022
  18. www.sciencedirect.com www.sciencedirect.com
    Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation
    1
    1. scibot 13 Apr 2022
      RRID:AB_2067317

      DOI: 10.1016/j.molcel.2022.03.026

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    sciencedirect.com/science/article/pii/S1097276522002647
  19. Feb 2022
  20. www.sciencedirect.com www.sciencedirect.com
    CRAF dimerization with ARAF regulates KRAS-driven tumor growth
    2
    1. scibot 11 Feb 2022
      RRID:AB_2067317

      DOI: 10.1016/j.celrep.2022.110351

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    2. scibot 09 Feb 2022
      RRID:AB_2067317

      DOI: 10.1016/j.celrep.2022.110351

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    sciencedirect.com/science/article/pii/S2211124722000675
  21. Dec 2021
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Association of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 With Angiotensin II Type 1 Receptor Impacts Mitochondrial Quality Control, Offering Promise for the Treatment of Vascular Senescence
    1
    1. scibot 04 Dec 2021
      RRID:AB_2067317

      DOI: 10.3389/fcvm.2021.788655

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    ncbi.nlm.nih.gov/pmc/articles/PMC8637926/
  23. Jun 2021
  24. www.sciencedirect.com www.sciencedirect.com
    Targeted mass-spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP kinase, and AKT signaling
    1
    1. scibot 15 Jun 2021
      RRID:AB_2067317

      DOI: 10.1016/j.crmeth.2021.100015

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    sciencedirect.com/science/article/pii/S2667237521000151
  25. May 2021
  26. www.sciencedirect.com www.sciencedirect.com
    ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization
    1
    1. scibot 05 May 2021
      RRID:AB_2067317

      DOI: 10.1016/j.devcel.2020.05.011

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    sciencedirect.com/science/article/pii/S1534580720304007
  27. Feb 2021
  28. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of BRAF and ERK1/2 has synergistic effects on thyroid cancer growth in vitro and in vivo
    1
    1. scibot 25 Feb 2021
      RRID:AB_2067317

      DOI: 10.1002/mc.23284

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    onlinelibrary.wiley.com/doi/full/10.1002/mc.23284
  29. Oct 2020
  30. elifesciences.org elifesciences.org
    Optical control of ERK and AKT signaling promotes axon regeneration and functional recovery of PNS and CNS in Drosophila
    1
    1. scibot 24 Oct 2020
      RRID:AB_2067317

      DOI: 10.7554/eLife.57395

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      Curator: @evieth

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    elifesciences.org/articles/57395
  31. Sep 2020
  32. www.sciencedirect.com www.sciencedirect.com
    Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis
    1
    1. scibot 23 Sep 2020
      RRID:AB_2067317

      DOI: 10.1016/j.cmet.2020.04.011

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1550413120301935
  33. www.sciencedirect.com www.sciencedirect.com
    Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
    1
    1. scibot 17 Sep 2020
      RRID:AB_2067317

      DOI: 10.1016/j.celrep.2020.107764

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    sciencedirect.com/science/article/pii/S2211124720307440
  34. www.sciencedirect.com www.sciencedirect.com
    Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids
    1
    1. scibot 16 Sep 2020
      RRID:AB_2067317

      DOI: 10.1016/j.cell.2020.05.053

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    sciencedirect.com/science/article/pii/S0092867420306863
  35. Jan 2020
  36. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:AB_2067317

      DOI: 10.1016/j.devcel.2019.04.014

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    sciencedirect.com/science/article/pii/S1534580719302849
  37. Nov 2018
  38. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S2211124718314980
  39. www.sciencedirect.com www.sciencedirect.com
    Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors
    1
    1. scibot 05 Nov 2018
      RRID:AB_2067317

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1535610818304161
  40. www.sciencedirect.com www.sciencedirect.com
    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S0092867418305865
  41. europepmc.org europepmc.org
    Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells
    1
    1. scibot 05 Nov 2018
      9427

      Curator: @evieth

      Curator note: Cell Signaling Technology Cat# 9427S, Phospho-c-Raf (Ser338) (56A6) Rabbit mAb antibody

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    europepmc.org/articles/PMC5941622/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
    1
    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.gov/pmc/articles/PMC5926201/
  43. www.sciencedirect.com www.sciencedirect.com
    Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1535610817305159
  44. www.sciencedirect.com www.sciencedirect.com
    KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S0092867417315003
  45. Nov 2017
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
    1
    1. scibot 08 Nov 2017
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    ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
  47. www.sciencedirect.com www.sciencedirect.com
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    1. scibot 08 Nov 2017
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    sciencedirect.com/science/article/pii/S2405471216304082