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  1. Last 7 days
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    Pharmacological and toxicological profiling of JAMC-4/108: targeted induction of apoptosis in human colorectal cancer cells
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    sciencedirect.com/science/article/pii/S0022356525402407
  3. Sep 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatiotemporal differential regulation of extrasynaptic GluN2B receptor subunits and PSA-NCAM in brain aging and Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12426952/
  5. Jun 2025
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    BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival
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    cell.com/molecular-cell/fulltext/S1097-2765(25)00499-X
  7. Apr 2025
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    Integrated pharmacoanalysis, bioinformatics analysis, and experimental validation to identify the ingredients and mechanisms of Xiao-Luo-Wan in uterine fibroids treatment
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  9. Feb 2025
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    Microglial pyroptosis drives neuropathic pain and targeting NLRP3 alleviates pain and neuroinflammation
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    sciencedirect.com/science/article/pii/S0925443925000821
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    Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity
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  12. Jan 2025
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    Muscle-derived small extracellular vesicles induce liver fibrosis during overtraining
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    Arginase Activity Inhibition With Thymoquinone Induces a Hybrid Type of Cell‐Death in MDA‐MB‐231 Cell Line
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    pmc.ncbi.nlm.nih.gov/articles/PMC11744436/
  15. Dec 2024
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    Fingolimod Inhibits C6 Rat Glioma Proliferation and Migration, Induces Sub-G1 Cell Cycle Arrest, Mitochondrial and Extrinsic Apoptosis In Vitro and Reduces Tumour Growth In Vivo
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  17. Oct 2024
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    Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application
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  19. Jul 2024
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    Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2-MAPK
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    Eupalinolide B suppresses pancreatic cancer by ROS generation and potential cuproptosis
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    Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor
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  23. May 2024
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    Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia
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  25. Mar 2024
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    A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis
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  27. Feb 2024
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    CircUSP1 as a novel marker promotes gastric cancer progression via stabilizing HuR to upregulate USP1 and Vimentin
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  29. Dec 2023
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    Design, synthesis and mechanistic anticancer activity of new acetylated 5-aminosalicylate-thiazolinone hybrid derivatives
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  31. Nov 2023
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    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
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    PRL2 inhibition elevates PTEN protein and ameliorates progression of acute myeloid leukemia
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    Inhibition of lysosome-tethered Ragulator-Rag-3D complex restricts the replication of Enterovirus 71 and Coxsackie A16
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  35. Sep 2023
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    Aggravated hepatic fibrosis induced by phenylalanine and tyrosine was ameliorated by chitooligosaccharides supplementation
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    URAT1 is expressed in cardiomyocytes and dotinurad attenuates the development of diet-induced metabolic heart disease.
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  38. Aug 2023
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  40. Feb 2023
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    Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity
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  42. Jan 2023
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    P38γ modulates the lipid metabolism in non-alcoholic fatty liver disease by regulating the JAK–STAT signaling pathway
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  44. Dec 2022
  45. www.science.org www.science.org
    Gasdermins and pannexin-1 mediate pathways of chemotherapy-induced cell lysis in hematopoietic malignancies
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    Celecoxib activates autophagy by inhibiting the mTOR signaling pathway and prevents apoptosis in nucleus pulposus cells
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    link.springer.com/article/10.1186/s40360-022-00633-y
  47. Jul 2022
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    Transmissible ER stress between macrophages and tumor cells configures tumor microenvironment
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  49. Jun 2022
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    Progesterone limits the tumor-promoting effects of the beta-subunit of human chorionic gonadotropin via non-nuclear receptors
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    sciencedirect.com/science/article/pii/S2589004222007982
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    Deficiency of C1QL1 reduced murine ovarian follicle reserve through intraovarian and endocrine control
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  52. May 2022
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    Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta-TC-6 cells via the generation of intracellular reactive oxygen species and mitochondrial superoxide
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  54. Apr 2022
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    Energetic metabolic reprogramming in Jurkat DFF40-deficient cancer cells
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    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
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    sciencedirect.com/science/article/pii/S0092867422003403
  57. Mar 2022
  58. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Poly (ADP-ribose) polymerase 1-mediated defective mitophagy contributes to painful diabetic neuropathy in the db/db model
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15606
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    The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
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    MicroRNA-101a-3p mimic ameliorates spinal cord... : Neural Regeneration Research
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  61. Feb 2022
  62. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway
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  63. Sep 2021
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    Roles of autophagy in relation to mitochondrial stress responses of HeLa cells to lamellarin cytotoxicity
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    sciencedirect.com/science/article/pii/S0300483X21002857
  65. Aug 2021
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    The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway
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  67. Jul 2021
  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Japanese Encephalitis Virus‐induced let‐7a/b interacted with the NOTCH‐TLR7 pathway in microglia and facilitated neuronal death via caspase activation
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14645
  69. rupress.org rupress.org
    Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination
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    rupress.org/jcb/article/220/6/e202006043/211984/Parkin-independent-mitophagy-via-Drp1-mediated
  70. Jun 2021
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC8201054/
  72. Apr 2021
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    Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition
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    Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases
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    sciencedirect.com/science/article/pii/S2211124721003120
  75. Sep 2020
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    A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling
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    sciencedirect.com/science/article/pii/S2211124720303442
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  78. Jan 2020
  79. www.sciencedirect.com www.sciencedirect.com
    Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles
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    sciencedirect.com/science/article/pii/S2211124719306199
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    Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer’s mouse model are associated with hippocampal synaptic deficits in an age-dependent manner
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  82. Nov 2018
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer
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  84. Nov 2017
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    Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages
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