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Extracellular Vesicles Favor Early Peripheral Immunosenescence Through Modulation of the Senescence-Associated Secretory Phenotype in HIV Infection

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1. scibot 16 Dec 2025
  
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  DOI: 10.1111/acel.70320
  
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onlinelibrary.wiley.com/doi/full/10.1111/acel.70320
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Cancer cells transfer invasive properties through microRNAs contained in collagen tracks

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1. scibot 13 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116725
  
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sciencedirect.com:5037/science/article/pii/S2211124725014974
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Macrophage PD-1 regulates energy expenditure and metabolic dysfunction under immune checkpoint blockade

1
1. scibot 11 Dec 2025
  
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  DOI: 10.1016/j.cmet.2025.11.009
  
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sciencedirect.com:5037/science/article/pii/S1550413125004930
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Exploring STEAP1 Expression in Prostate Cancer Cells in Response to Androgen Deprivation and in Small Extracellular Vesicles

1
1. scibot 06 Dec 2025
  
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  DOI: 10.1158/1541-7786.MCR-24-0903
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12133427/
Oct 2025
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Expansion of secreted cystine knot proteins reveals virulence factors in the human fungal pathogen Histoplasma

1
1. scibot 28 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116465
  
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sciencedirect.com/science/article/pii/S2211124725012367
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The proteostatic landscape of healthy human oocytes

1
1. scibot 21 Aug 2025
  
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  DOI: 10.1038/s44318-025-00493-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12361380/
www.cell.com www.cell.com

A mechano-resistance mechanism in skin adapts to terrestrial locomotion

1
1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.cell.2025.07.012
  
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cell.com/cell/fulltext/S0092-8674(25)00801-3
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Tacrine‐Induced Endoplasmic Reticulum Stress in AChE‐Expressed Cells Leads to Improper Assembly and Transport of the Oligomeric Enzyme: Reversal by Trehalose

1
1. scibot 07 Aug 2025
  
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  RRID:AB_2069006
  
  DOI: 10.1111/jnc.70178
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12322807/
Jun 2025
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 18 Jun 2025
  
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  RRID:AB_2069006
  
  DOI: 10.1158/1535-7163.mct-25-0117
  
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2. scibot 17 Jun 2025
  
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  DOI: 10.1158/1535-7163.mct-25-0117
  
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52.53.155.43/4c4ba8e26a369e7baf8cacabd22776836e074b0d/PDF-html.html
elifesciences.org elifesciences.org

Isolating Small Extracellular Vesicles from Small Volumes of Blood Plasma using size exclusion chromatography and density gradient ultracentrifugation: A Comparative Study

1
1. scibot 11 Jun 2025
  
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  ab22595, Abcam
  
  DOI: 10.7554/eLife.92796.2
  
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elifesciences.org/reviewed-preprints/92796v2
May 2025
www.sciencedirect.com www.sciencedirect.com

Paraoxonase-like APMAP maintains endoplasmic-reticulum-associated lipid and lipoprotein homeostasis

1
1. scibot 17 May 2025
  
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  DOI: 10.1016/j.devcel.2025.04.008
  
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sciencedirect.com/science/article/pii/S1534580725002102
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Spatial proteomics of ER tubules reveals CLMN, an ER-actin tether at focal adhesions that promotes cell migration

1
1. scibot 05 Apr 2025
  
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  RRID:AB_2069006
  
  DOI: 10.1016/j.celrep.2025.115502
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12416146/
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Remote limb ischemic conditioning alleviates steatohepatitis via extracellular vesicle-mediated muscle-liver crosstalk

1
1. scibot 01 Apr 2025
  
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  RRID:AB_2069006
  
  DOI: 10.1016/j.cmet.2025.02.009
  
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sciencedirect.com/science/article/pii/S1550413125000671
Mar 2025
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Single extracellular vesicle detection assay identifies membrane-associated α-synuclein as an early-stage biomarker in Parkinson’s disease

1
1. scibot 11 Mar 2025
  
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  RRID:AB_2069006
  
  DOI: 10.1016/j.xcrm.2025.101999
  
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sciencedirect.com/science/article/pii/S2666379125000722
Feb 2025
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Compositionally unique mitochondria in filopodia support cellular migration

1
1. scibot 20 Feb 2025
  
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  RRID:AB_2069006
  
  DOI: 10.1016/j.cub.2025.01.062
  
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sciencedirect.com/science/article/pii/S0960982225001253
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HSPA8 dampens SCAP/INSIG split and SREBP activation by reducing PKR-mediated INSIG phosphorylation

1
1. scibot 20 Feb 2025
  
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  RRID:AB_2069006
  
  DOI: 10.1016/j.celrep.2025.115339
  
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sciencedirect.com/science/article/pii/S221112472500110X
Jan 2025
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Exosomal miR-302b rejuvenates aging mice by reversing the proliferative arrest of senescent cells

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1. scibot 16 Jan 2025
  
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  RRID:AB_2069006
  
  DOI: 10.1016/j.cmet.2024.11.013
  
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sciencedirect.com/science/article/pii/S1550413124004819
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Blood-derived APLP1+ extracellular vesicles are potential biomarkers for the early diagnosis of brain diseases

1
1. scibot 04 Jan 2025
  
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  RRID:AB_2069006
  
  DOI: 10.1126/sciadv.ado6894
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11691634/
www.science.org www.science.org

Blood-derived APLP1+ extracellular vesicles are potential biomarkers for the early diagnosis of brain diseases

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1. scibot 04 Jan 2025
  
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  DOI: 10.1126/sciadv.ado6894
  
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science.org/doi/10.1126/sciadv.ado6894
52.53.155.43 52.53.155.43

1-s2.0-S2589004224029377-main-html.html

1
1. scibot 03 Jan 2025
  
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  RRID:AB_2069006
  
  DOI: 10.1016/j.isci.2024.111710
  
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52.53.155.43/a4a95d0f48e4f5d6b60e2092f92dc9e622c6d3c5/1-s2.0-S2589004224029377-main-html.html
Dec 2024
www.sciencedirect.com www.sciencedirect.com

Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus

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1. scibot 10 Dec 2024
  
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  RRID:AB_2069006
  
  DOI: 10.1016/j.immuni.2024.11.003
  
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sciencedirect.com/science/article/pii/S1074761324005132
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Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening

1
1. scibot 10 Dec 2024
  
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  RRID:AB_2069006
  
  DOI: 10.1016/j.cels.2024.11.004
  
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sciencedirect.com/science/article/pii/S2405471224003375
52.53.155.43 52.53.155.43

ssrn-5035905-html.html

1
1. scibot 06 Dec 2024
  
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  RRID:AB_2069006
  
  DOI: 10.3389/fvets.2021.663656
  
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52.53.155.43/e64f14dc3220054f5f79a6a960474479f277202c/ssrn-5035905-html.html
www.biorxiv.org www.biorxiv.org

Cell-specific oxidative metabolism of the renal cortex

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1. scibot 06 Dec 2024
  
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  RRID:AB_2069006
  
  DOI: 10.1101/2024.11.24.622516
  
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biorxiv.org/content/10.1101/2024.11.24.622516v1
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Highlights from MBoC Selection: Differential reliance of CTD-nuclear envelope phosphatase 1 on its regulatory subunit in ER lipid synthesis and storage

1
1. scibot 26 Sep 2024
  
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  AB_2069006
  
  DOI: 10.1091/mbc.E23-09-0382
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11244170/
Jul 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine

1
1. scibot 18 Jul 2024
  
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  RRID:AB_2069006
  
  DOI: 10.1038/s41422-024-00985-6
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11442470/
www.cell.com www.cell.com

Engineering an energy-dissipating hybrid tissue in vivo for obesity treatment

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1. scibot 12 Jul 2024
  
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  RRID:AB_2069006
  
  DOI: 10.1016/j.celrep.2024.114425
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00754-X
Jun 2024
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TRABD modulates mitochondrial homeostasis and tissue integrity

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  DOI: 10.1016/j.celrep.2024.114304
  
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sciencedirect.com/science/article/pii/S2211124724006326
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington’s disease

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1. scibot 23 May 2024
  
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  DOI: 10.1126/sciadv.adl2036
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11100560/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening

1
1. scibot 28 Apr 2024
  
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  RRID:AB_2069006
  
  DOI: 10.1101/2024.04.07.588166
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11030420/
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Human brain small extracellular vesicles contain selectively packaged, full-length mRNA

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1. scibot 09 Apr 2024
  
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  AbcamCat# ab22595, RRID:AB_2069006
  
  DOI: 10.1016/j.celrep.2024.114061
  
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2. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114061
  
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sciencedirect.com/science/article/pii/S2211124724003899
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pla2g12b drives expansion of triglyceride-rich lipoproteins

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1. scibot 12 Mar 2024
  
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  RRID:AB_2069006
  
  DOI: 10.1038/s41467-024-46102-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10920679/
Feb 2024
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Mouse oocytes sequester aggregated proteins in degradative super-organelles

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1. scibot 21 Feb 2024
  
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  RRID:AB_2069006
  
  DOI: 10.1016/j.cell.2024.01.031
  
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sciencedirect.com/science/article/pii/S0092867424000680
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Phospholipids with two polyunsaturated fatty acyl tails promote ferroptosis

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1. scibot 16 Feb 2024
  
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  RRID:AB_2069006
  
  DOI: 10.1016/j.cell.2024.01.030
  
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Prenatal hormone stress triggers embryonic cardiac hypertrophy outcome by ubiquitin-dependent degradation of mitochondrial mitofusin 2

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Subcytoplasmic location of translation controls protein output

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Ubiquiton—An inducible, linkage-specific polyubiquitylation tool

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EDEM1 regulates the insulin mRNA level by inhibiting the endoplasmic reticulum stress-induced IRE1/JNK/c-Jun pathway

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V-ATPase recruitment to ER exit sites switches COPII-mediated transport to lysosomal degradation

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Regulation of ERK2 activity by dynamic S-acylation

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Fusobacterium nucleatum promotes colorectal cancer metastasis by excretion of miR-122-5p from cells via exosomes

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Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes

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Methionine oxidation selectively enhances T cell reactivity against a melanoma antigen

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Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis

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The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB

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Mitochondrial Bcl-xL promotes brain synaptogenesis by controlling non-lethal caspase activation

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Defining basic rules for hardening influenza A virus liquid condensates

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Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release

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Exosomes from bone marrow mesenchymal stem cells are a... : Neural Regeneration Research

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Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes

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Exosomal MicroRNA Profiling in Vitreous Humor Derived From Pathological Myopia Patients

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The CNC-family transcription factor Nrf3 coordinates the melanogenesis cascade through macropinocytosis and autophagy regulation

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Methylmalonic acid levels in serum, exosomes, and urine and its association with cblC type methylmalonic acidemia-induced cognitive impairment

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The Golgi-resident protein ACBD3 concentrates STING at ER-Golgi contact sites to drive export from the ER

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Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages

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Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis

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S-palmitoylation of tyrosinase at cysteine500 regulates melanogenesis

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Processing and Subcellular Localization of the Hepatitis E Virus Replicase: Identification of Candidate Viral Factories

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Self-assembly of pericentriolar material in interphase cells lacking centrioles

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KIBRA regulates amyloid β metabolism by controlling extracellular vesicles secretion

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Processing and Subcellular Localization of the Hepatitis E Virus Replicase: Identification of Candidate Viral Factories

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Metabolic incorporation of electron-rich ribonucleosides enhances APEX-seq for profiling spatially restricted nascent transcriptome

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Tissue differences in the exosomal/small extracellular vesicle proteome and their potential as indicators of altered tissue metabolism

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Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation

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Intestinal goblet cells sample and deliver lumenal antigens by regulated endocytic uptake and transcytosis

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Dual film-like organelles enable spatial separation of orthogonal eukaryotic translation

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APD-Containing Cyclolipodepsipeptides Target Mitochondrial Function in Hypoxic Cancer Cells

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Untitled document

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Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress

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ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function

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sciencedirect.com/science/article/pii/S2589004221007264
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A Membrane-Bound Diacylglycerol Species Induces PKCϵ-Mediated Hepatic Insulin Resistance

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1. scibot 29 Apr 2021
  
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  DOI: 10.1016/j.cmet.2020.08.001
  
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Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum

1
1. scibot 27 Apr 2021
  
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  DOI: 10.1016/j.chembiol.2020.10.003
  
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Mar 2021
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Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling

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1. scibot 22 Mar 2021
  
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  DOI: 10.1016/j.molcel.2021.01.009
  
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sciencedirect.com/science/article/pii/S1097276521000095
Feb 2021
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EphA7 promotes myogenic differentiation via cell-cell contact

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  DOI: 10.7554/eLife.53689
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7173967/
Sep 2020
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The Potential Therapeutic Role of Exosomal MicroRNA-520b Derived from Normal Fibroblasts in Pancreatic Cancer

2
1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.omtn.2019.12.029
  
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  DOI: 10.1016/j.omtn.2019.12.029
  
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rupress.org rupress.org

GRAF2, WDR44, and MICAL1 mediate Rab8/10/11–dependent export of E-cadherin, MMP14, and CFTR ΔF508

1
1. scibot 25 Sep 2020
  
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  DOI: 10.1083/jcb.201811014
  
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Genome-wide CRISPR screening identifies new regulators of glycoprotein secretion

1
1. scibot 23 Sep 2020
  
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  DOI: 10.12688/wellcomeopenres.15232.2
  
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Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage

1
1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.cmet.2020.06.004
  
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SFTSV Infection Induces BAK/BAX-Dependent Mitochondrial DNA Release to Trigger NLRP3 Inflammasome Activation

1
1. scibot 16 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.02.105
  
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The Mitochondria-Associated ER Membranes Are Novel Subcellular Locations Enriched for Inflammatory-Responsive MicroRNAs

1
1. scibot 16 Sep 2020
  
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  DOI: 10.1007/s12035-020-01937-y
  
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Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

1
1. scibot 05 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107840
  
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Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.05.095
  
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Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.cell.2019.07.002
  
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Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy

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1. scibot 13 Jan 2020
  
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  RRID:AB_2069006
  
  DOI: 10.1038/s41467-019-10345-3
  
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nature.com/articles/s41467-019-10345-3
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Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.molcel.2019.06.040
  
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Cyfip1 haploinsufficiency does not alter GABAA receptor δ-subunit expression and tonic inhibition in dentate gyrus PV+ interneurons and granule cells

1
1. scibot 13 Jan 2020
  
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  AB_2069006
  
  DOI: 10.1523/ENEURO.0364-18.2019
  
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eneuro.org/content/6/3/ENEURO.0364-18.2019
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Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.05.008
  
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The N-Degron Pathway Mediates ER-phagy

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2069006
  
  DOI: 10.1016/j.molcel.2019.06.028
  
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sciencedirect.com/science/article/pii/S109727651930485X
Nov 2018
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GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death

1
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sciencedirect.com/science/article/pii/S2451945617304233
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NADH Shuttling Couples Cytosolic Reductive Carboxylation of Glutamine with Glycolysis in Cells with Mitochondrial Dysfunction

2
1. scibot 05 Nov 2018
  
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2. scibot 05 Nov 2018
  
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Organelle Specific O-Glycosylation Drives MMP14 Activation, Tumor Growth, and Metastasis

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1535610817304543

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