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Torsins organize CLCC1 assembly to safeguard ER bilayer and lipid homeostasis

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Jul 2026
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FAM134B-mediated ER-phagy degrades APP and suppresses Alzheimer’s disease pathology

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pmc.ncbi.nlm.nih.gov/articles/PMC13324857/
Jun 2026
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The TNRC6B/circTNRC6B axis drives lymphovascular invasion and metastasis through an intragenic self-degradation loop

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Serum SOS1 as a prognostic biomarker and therapeutic target for progressive liver disease

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The C-terminal region of TENT5 proteins drives ER-associated mRNA polyadenylation via FNDC3 interaction

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May 2026
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Farnesylation-driven KRAS phase separation promotes colon tumor growth

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Apr 2026
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Acyltransferase ZDHHC22 promotes N-Myc transcriptional activation to drive neuroblastoma progression and chemoresistance

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Yellow Fever Virus Interactomes Reveal Common and Divergent Strategies of Replication and Evolution for Mosquito-borne Flaviviruses

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TRIM27-controlled endothelium-derived exosomes play a central role in podocyte injury in diabetic kidney disease

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Mar 2026
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Collagen-bearing exosomes from breast cancer-associated fibroblasts promote T cell dysfunction

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pmc.ncbi.nlm.nih.gov/articles/PMC13012019/
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Control of lysosome function by the GTPase-activating protein TBC1D9B and its binding partner TMEM55B

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Young Regulatory T Cell-Derived Extracellular Vesicles Improve Mitochondrial Function and Angiogenesis and Suppress Inflammation in Senescent Brain and Heart

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Feb 2026
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Mutant PLP1 impairs COPII vesicle formation via ER calcium depletion in Pelizaeus-Merzbacher disease

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  DOI: 10.1016/j.nbd.2026.107329
  
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Acutely denervated muscle EVs reshape neuronal mitochondrial metabolism via retrograde signaling to rescue peripheral nerve injury

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Jan 2026
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Unconventional Secretion of Angiogenic Sonic Hedgehog–Containing Extra-Large Extracellular Vesicles is Driven by PI3K–Rab18-GDP Signalling

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isevjournals.onlinelibrary.wiley.com/doi/10.1002/jex2.70112
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Limiting ER-associated degradation capacity triggers acute and chronic effects on insulin biosynthesis

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1. scibot 23 Jan 2026
  
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A GluN2B disease-associated variant promotes the degradation of NMDA receptors via autophagy

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Dec 2025
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5′ UTR-mediated retention of eIF3 on 80S ribosomes promotes co-translational folding of ER membrane proteins

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Nov 2025
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The lipid droplet protein DHRS3 is a regulator of melanoma cell state

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pmc.ncbi.nlm.nih.gov/articles/PMC12244328/
Oct 2025
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Extracellular vesicle derived miRNAs from plasma as promising diagnosis and prognosis biomarkers for neuroblastoma

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Sep 2025
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Liver-breast communication of adipocyte-oriented exosomes drives primary mammary cancer progression

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Aug 2025
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ER-phagy and proteostasis defects prime pancreatic epithelial state changes in KRAS-mediated oncogenesis

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Jul 2025
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Disulfide bond-mediated stabilization of the oligomers of UDP-glucuronosyltransferase 2B7

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Jun 2025
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Protocol for isolating extracellular vesicles from human or mouse airway macrophages for functional assays and in vivo or in vitro experimentation

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May 2025
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YTHDF1 differentiates the contributing roles of mTORC1 in aging

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Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response

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Feb 2025
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Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3

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Jan 2025
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Muscle-derived small extracellular vesicles induce liver fibrosis during overtraining

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Nov 2024
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Kinesin-1 mediates proper ER folding of the CaV1.2 channel and maintains mouse glucose homeostasis

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Aug 2024
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Role of a holo-insertase complex in the biogenesis of biophysically diverse ER membrane proteins

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Jul 2024
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Kinesin-1 mediates proper ER folding of the CaV1.2 channel and maintains mouse glucose homeostasis

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  DOI: 10.1101/2024.06.24.600327
  
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May 2024
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An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins

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Mar 2024
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Combinatorial selective ER-phagy remodels the ER during neurogenesis

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  DOI: 10.1038/s41556-024-01356-4
  
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Jan 2024
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OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB

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  DOI: 10.1016/j.molcel.2023.11.042
  
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Dec 2023
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Exosome-mediated delivery of miR-519e-5p promotes malignant tumor phenotype and CD8+ T-cell exhaustion in metastatic PTC

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1. scibot 17 Dec 2023
  
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A Proximity Labeling Strategy Enables Proteomic Analysis of Inter-organelle Membrane Contacts

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Exosomes derived from human umbilical cord mesenchymal stem cells alleviate Parkinson’s disease and neuronal damage through inhibition of microglia

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The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity

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Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity

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ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy

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ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer

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MOSPD2 is an endoplasmic reticulum–lipid droplet tether functioning in LD homeostasis

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Extracellular Vesicles Secreted by Mouse Decidual Cells Carry Critical Information for the Establishment of Pregnancy

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De novo sphingolipid biosynthesis necessitates detoxification in cancer cells

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TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation

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FAM69C, a kinase critical for synaptic function and memory, is defective in neurodegenerative dementia

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VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion

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Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation

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Untitled document

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Sep 2020
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APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin

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TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress

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AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity

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A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes

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