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Adoptive macrophages suppress glioblastoma growth by reversing immunosuppressive microenvironment through programmed phenotype repolarization

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  DOI: 10.1016/j.celrep.2025.116350
  
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sciencedirect.com/science/article/pii/S2211124725011210
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tumor integrin-targeted glucose oxidase enzyme promotes ROS-mediated cell death that combines with interferon alpha therapy for tumor control

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1. scibot 04 Jul 2025
  
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  DOI: 10.1158/1535-7163.MCT-24-0163
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11695183/
Jun 2025
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Plinabulin following radiation enhances dendritic cell maturation and checkpoint inhibitor retreatment of relapsed/refractory cancers

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.medj.2025.100752
  
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sciencedirect.com/science/article/pii/S2666634025001795
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MET pathway inhibition increases chemo-immunotherapy efficacy in small cell lung cancer

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102194
  
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sciencedirect.com/science/article/pii/S2666379125002678
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PINK1 deficiency rewires early immune responses in a mouse model of Parkinson’s disease triggered by intestinal infection

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1. scibot 28 May 2025
  
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  DOI: 10.1038/s41531-025-00945-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12098848/
Mar 2025
www.cell.com www.cell.com

Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response

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1. scibot 04 Mar 2025
  
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  DOI: 10.1016/j.cell.2025.01.043
  
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cell.com/cell/abstract/S0092-8674(25)00145-X
Feb 2025
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ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation

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1. scibot 13 Feb 2025
  
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  DOI: 10.1016/j.cell.2025.01.027
  
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sciencedirect.com/science/article/pii/S0092867425000960
Nov 2024
52.53.155.43 52.53.155.43

strobl-et-al-2024-jak-stat1-as-therapeutic-target-for-egfr-deficiency-associated-inflammation-and-scarring-alopecia-html.html

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44321-024-00166-3
  
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52.53.155.43/586ba8b525e8da6306112d5dd7635949084313ca/strobl-et-al-2024-jak-stat1-as-therapeutic-target-for-egfr-deficiency-associated-inflammation-and-scarring-alopecia-html.html
www.embopress.org www.embopress.org

JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44321-024-00166-3
  
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embopress.org/doi/10.1038/s44321-024-00166-3
Aug 2024
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Non-classical monocytes scavenge the growth factor CSF1 from endothelial cells in the peripheral vascular tree to ensure survival and homeostasis

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1. scibot 01 Aug 2024
  
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  DOI: 10.1016/j.immuni.2024.07.005
  
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sciencedirect.com/science/article/pii/S1074761324003546
Jun 2024
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Protein-energy restriction-induced lipid metabolism disruption causes stable-to-progressive disease shift in Mycobacterium avium-infected female mice

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.ebiom.2024.105198
  
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sciencedirect.com/science/article/pii/S2352396424002330
Apr 2024
www.pnas.org www.pnas.org

Claudin-2 upregulation enhances intestinal permeability, immune activation, dysbiosis, and mortality in sepsis

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1. scibot 25 Apr 2024
  
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  DOI: 10.1073/pnas.2217877121
  
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pnas.org/doi/abs/10.1073/pnas.2217877121
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Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration

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1. scibot 19 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114114
  
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sciencedirect.com/science/article/pii/S221112472400442X
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A LTB4/CD11b self-amplifying loop drives pyogranuloma formation in chronic granulomatous disease

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1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.isci.2024.109589
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11016758/
Feb 2024
52.53.155.43 52.53.155.43

Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege

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1. scibot 23 Feb 2024
  
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  DOI: 10.1101/2023.10.11.561653
  
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52.53.155.43/96ec307650875a091f9342a8f5a3978ef308aaef/2023.10.11.561653v1.full-html.html
Oct 2023
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Ketogenesis promotes tolerance to Pseudomonas aeruginosa pulmonary infection

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.cmet.2023.09.001
  
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sciencedirect.com/science/article/pii/S1550413123003327
Apr 2023
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Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells

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1. scibot 27 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112431
  
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sciencedirect.com/science/article/pii/S2211124723004424
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Maternal diet modulates the infant microbiome and intestinal Flt3L necessary for dendritic cell development and immunity to respiratory infection

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1. scibot 20 Apr 2023
  
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  DOI: 10.1016/j.immuni.2023.03.002
  
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sciencedirect.com/science/article/pii/S107476132300119X
Mar 2023
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T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity

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1. scibot 28 Mar 2023
  
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  DOI: 10.1016/j.immuni.2023.02.016
  
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sciencedirect.com/science/article/pii/S1074761323000900
Jan 2023
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Protocol to assess the antitumor efficacy of an immunotherapeutic peptide in syngeneic orthotopic glioma mouse models

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1. scibot 21 Jan 2023
  
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  DOI: 10.1016/j.xpro.2023.102049
  
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sciencedirect.com/science/article/pii/S2666166723000072
Nov 2022
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Isolating and targeting a highly active, stochastic dendritic cell subpopulation for improved immune responses

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  DOI: 10.1016/j.celrep.2022.111563
  
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sciencedirect.com/science/article/pii/S2211124722014243
Sep 2022
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Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease

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1. scibot 30 Sep 2022
  
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  DOI: 10.1016/j.cell.2022.09.007
  
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sciencedirect.com/science/article/pii/S0092867422011291
www.nature.com www.nature.com

BCGΔBCG1419c increased memory CD8+ T cell-associated immunogenicity and mitigated pulmonary inflammation compared with BCG in a model of chronic tuberculosis

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1. scibot 24 Sep 2022
  
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  DOI: 10.1038/s41598-022-20017-w
  
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nature.com/articles/s41598-022-20017-w
May 2022
www.mdpi.com www.mdpi.com

Ex-Vivo Skin Explant Culture Is a Model for TSLP-Mediated Skin Barrier Immunity

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1. scibot 26 May 2022
  
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  DOI: 10.3390/life11111237
  
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mdpi.com/2075-1729/11/11/1237/htm
Apr 2022
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Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection

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  DOI: 10.1016/j.cmet.2022.03.009
  
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sciencedirect.com/science/article/pii/S1550413122000973
Mar 2022
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Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration

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1. scibot 09 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110473
  
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sciencedirect.com/science/article/pii/S2211124722002066
Nov 2021
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Single-cell transcriptomics reveals opposing roles of Shp2 in Myc-driven liver tumor cells and microenvironment

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  DOI: 10.1016/j.celrep.2021.109974
  
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sciencedirect.com/science/article/pii/S2211124721014534
www.cell.com www.cell.com

TNF leads to mtDNA release and cGAS/STING-dependent interferon responses that support inflammatory arthritis

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1. scibot 10 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.109977
  
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cell.com/cell-reports/fulltext/S2211-1247(21)01456-X
Sep 2021
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Acquisition of murine splenic myeloid cells for protein and gene expression profiling by advanced flow cytometry and CITE-seq

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  DOI: 10.1016/j.xpro.2021.100842
  
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sciencedirect.com/science/article/pii/S2666166721005487
Aug 2021
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Dual targeting of lymphocyte homing and retention through α4β7 and αEβ7 inhibition in inflammatory bowel disease

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1. scibot 18 Aug 2021
  
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  DOI: 10.1016/j.xcrm.2021.100381
  
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sciencedirect.com/science/article/pii/S2666379121002354
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Intercellular cGAMP transmission induces innate immune activation and tissue inflammation in Trex1 deficiency

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1. scibot 16 Aug 2021
  
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  DOI: 10.1016/j.isci.2021.102833
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8326191/
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Untitled document

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  DOI: 10.1016/j.celrep.2018.11.054
  
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sciencedirect.com/science/article/pii/S2211124718318175
Jun 2021
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An acquired acyltransferase promotes Klebsiella pneumoniae ST258 respiratory infection

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1. scibot 02 Jun 2021
  
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  DOI: 10.1016/j.celrep.2021.109196
  
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sciencedirect.com/science/article/pii/S2211124721005428
May 2021
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Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells

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1. scibot 29 May 2021
  
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  DOI: 10.1016/j.immuni.2021.05.008
  
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sciencedirect.com/science/article/pii/S1074761321002144
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Intestinal barrier dysfunction plays an integral role in arthritis pathology and can be targeted to ameliorate disease

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1. scibot 14 May 2021
  
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  DOI: 10.1016/j.medj.2021.04.013
  
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sciencedirect.com/science/article/pii/S2666634021001628
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Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche That Maintains and Replenishes Splenic Red Pulp Macrophages

1
1. scibot 06 May 2021
  
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  RRID:AB_2069377
  
  DOI: 10.1016/j.immuni.2020.06.008
  
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sciencedirect.com/science/article/pii/S1074761320302387
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Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity

1
1. scibot 06 May 2021
  
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  RRID:AB_2069377
  
  DOI: 10.1016/j.immuni.2020.05.001
  
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sciencedirect.com/science/article/pii/S1074761320301825
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Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy

1
1. scibot 05 May 2021
  
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  RRID:AB_2069377
  
  DOI: 10.1016/j.celrep.2021.109071
  
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ncbi.nlm.nih.gov/labs/pmc/articles/PMC8148423/
Apr 2021
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Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation

1
1. scibot 29 Apr 2021
  
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  RRID:AB_2069377
  
  DOI: 10.1016/j.cmet.2020.04.017
  
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sciencedirect.com/science/article/pii/S1550413120301996
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Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis

1
1. scibot 24 Apr 2021
  
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  RRID:AB_2069377
  
  DOI: 10.1016/j.cell.2020.08.020
  
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sciencedirect.com/science/article/pii/S0092867420310114
Sep 2020
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Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization

1
1. scibot 23 Sep 2020
  
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  RRID:AB_2069377
  
  DOI: 10.1016/j.celrep.2020.107679
  
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sciencedirect.com/science/article/pii/S221112472030632X
www.cell.com www.cell.com

Rewilding Nod2 and Atg16l1 Mutant Mice Uncovers Genetic and Environmental Contributions to Microbial Responses and Immune Cell Composition

1
1. scibot 23 Sep 2020
  
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  RRID:AB_2069377
  
  DOI: 10.1016/j.chom.2020.03.001
  
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cell.com/cell-host-microbe/fulltext/S1931-3128(20)30124-4
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Altered Immunity of Laboratory Mice in the Natural Environment Is Associated with Fungal Colonization

1
1. scibot 17 Sep 2020
  
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  RRID:AB_2069377
  
  DOI: 10.1016/j.chom.2020.02.015
  
  Resource: (BioLegend Cat# 107628, RRID:AB_2069377)
  
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sciencedirect.com/science/article/pii/S1931312820301232
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Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment

1
1. scibot 17 Sep 2020
  
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  RRID:AB_2069377
  
  DOI: 10.1016/j.celrep.2019.12.034
  
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sciencedirect.com/science/article/pii/S2211124719316845
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CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b−CD103+ DCs

1
1. scibot 16 Sep 2020
  
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  RRID:AB_2069377
  
  DOI: 10.1016/j.celrep.2020.02.103
  
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sciencedirect.com/science/article/pii/S2211124720302849
Jan 2020
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Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2069377
  
  DOI: 10.1016/j.immuni.2019.08.006
  
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sciencedirect.com/science/article/pii/S1074761319303322
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Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2069377
  
  DOI: 10.1016/j.immuni.2019.11.009
  
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sciencedirect.com/science/article/pii/S107476131930490X
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Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2069377
  
  DOI: 10.1016/j.immuni.2019.06.010
  
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sciencedirect.com/science/article/pii/S1074761319302808
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Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2069377
  
  DOI: 10.1016/j.immuni.2019.09.014
  
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sciencedirect.com/science/article/pii/S1074761319304108
Nov 2018
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Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2069377
  
  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S1097276518302788