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Metabolic profiling reveals pyrimidine synthesis enzyme CAD as a central carbon metabolism signaling node in cancer cell proliferation

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1. scibot 09 Apr 2026
  
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  DOI: 10.1016/j.molcel.2026.03.016
  
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sciencedirect.com/science/article/pii/S1097276526001929
Jan 2026
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Simultaneous targeting of KRAS and CDK4 synergistically induces durable growth arrest in pancreatic cancer cells

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1. scibot 30 Jan 2026
  
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  DOI: 10.1038/s41419-025-08362-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12847887/
Nov 2025
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Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation

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1. scibot 01 Nov 2025
  
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  DOI: 10.1016/j.cmet.2025.10.003
  
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sciencedirect.com/science/article/pii/S1550413125004371
May 2025
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CDK4/6 activity is required during G2 arrest to prevent stress induced endoreplication

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1. scibot 20 May 2025
  
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  DOI: 10.1126/science.adi2421
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11305671/
Jul 2024
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Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton

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1. scibot 17 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114510
  
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sciencedirect.com/science/article/pii/S2211124724008398
May 2024
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CDK4/6 activity is required during G2 arrest to prevent stress-induced endoreplication

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1. scibot 03 May 2024
  
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  DOI: 10.1126/science.adi2421
  
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science.org/doi/10.1126/science.adi2421
Apr 2024
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The MYCN 5′ UTR as a therapeutic target in neuroblastoma

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1. scibot 25 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114134
  
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sciencedirect.com/science/article/pii/S2211124724004625
Mar 2024
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Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice

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1. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113875
  
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2. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113875
  
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sciencedirect.com/science/article/pii/S2211124724002031
Dec 2023
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Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation

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1. scibot 29 Dec 2023
  
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  DOI: 10.1002/advs.202305620
  
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onlinelibrary.wiley.com/doi/10.1002/advs.202305620
Jul 2022
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GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment

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1. scibot 15 Jul 2022
  
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  DOI: 10.1016/j.cmet.2022.06.010
  
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sciencedirect.com/science/article/pii/S1550413122002303
Mar 2022
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BPS Publications

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1. scibot 31 Mar 2022
  
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  DOI: 10.1111/bph.14558
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14558
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CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities

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1. scibot 02 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110448
  
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sciencedirect.com/science/article/pii/S2211124722001759
Dec 2021
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Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2

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1. scibot 17 Dec 2021
  
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  DOI: 10.7554/eLife.70691
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8670743/
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Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation

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1. scibot 01 Dec 2021
  
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  DOI: 10.1016/j.devcel.2021.11.009
  
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sciencedirect.com/science/article/pii/S1534580721008947
Sep 2021
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CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models

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1. scibot 25 Sep 2021
  
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  DOI: 10.1016/j.xcrm.2021.100394
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8484689/
Aug 2021
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Untitled document

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1. scibot 10 Aug 2021
  
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  RRID:AB_2071200
  
  DOI: 10.1111/bph.14558
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14558
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Cell-Cycle Proteins Control Production of Neutrophil Extracellular Traps

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1. scibot 04 Aug 2021
  
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  DOI: 10.1016/j.devcel.2017.10.013
  
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sciencedirect.com/science/article/pii/S1534580717308262
Jul 2021
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RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway

1
1. scibot 31 Jul 2021
  
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  cyclin E1
  
  DOI: 10.1186/s40659-019-0268-x
  
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  RRID:AB_2071200 RRIDCUR:Missing
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link.springer.com/article/10.1186/s40659-019-0268-x
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FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer

1
1. scibot 31 Jul 2021
  
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  DOI: 10.1016/j.celrep.2019.02.054
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6425951/
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Untitled document

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1. scibot 31 Jul 2021
  
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  DOI: 10.1016/j.celrep.2019.02.054
  
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sciencedirect.com/science/article/pii/S2211124719302335
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SARNP, a participant in mRNA splicing and export, negatively regulates E‐cadherin expression via interaction with pinin

1
1. scibot 29 Jul 2021
  
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  cyclin E1
  
  DOI: 10.1002/jcp.29073
  
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onlinelibrary.wiley.com/doi/full/10.1002/jcp.29073
May 2021
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Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease

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1. scibot 21 May 2021
  
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  DOI: 10.1016/j.molcel.2021.04.028
  
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sciencedirect.com/science/article/pii/S1097276521003579
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mTOR signaling regulates gastric epithelial progenitor homeostasis and gastric tumorigenesis via MEK1-ERKs and BMP-Smad1 pathways

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1. scibot 05 May 2021
  
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  DOI: 10.1016/j.celrep.2021.109069
  
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sciencedirect.com/science/article/pii/S2211124721004009
Sep 2020
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Deamidation Shunts RelA from Mediating Inflammation to Aerobic Glycolysis

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1. scibot 16 Sep 2020
  
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  DOI: 10.1016/j.cmet.2020.04.006
  
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sciencedirect.com/science/article/pii/S1550413120301881
Jan 2020
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CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.ccell.2019.11.003
  
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sciencedirect.com/science/article/pii/S1535610819305239
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Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.chembiol.2019.05.005
  
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sciencedirect.com/science/article/pii/S2451945619301746
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HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.molcel.2019.05.034
  
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sciencedirect.com/science/article/pii/S109727651930406X
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The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.06.055
  
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sciencedirect.com/science/article/pii/S2211124719308289
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.02.054
  
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sciencedirect.com/science/article/pii/S2211124719302335
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2071200
  
  DOI: 10.1016/j.celrep.2019.02.054
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6425951/
Nov 2018
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Untitled document

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S2211124718314116
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Time-Dependent Molecular Responses Differ between Gastric Bypass and Dieting but Are Conserved Across Species

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1550413118303863
Nov 2017
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Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a

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1. scibot 08 Nov 2017
  
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  AB_2071200
  
  Curator: @Zeljana_Babic
  
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  RRID:AB_2071200 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2451945617300636
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Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation

1
1. scibot 08 Nov 2017
  
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  AB_2071200
  
  Curator: @gabimpine
  
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sciencedirect.com/science/article/pii/S0092867416309734