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EZH1/2 inhibition improves immunotherapy response through MHC Class II de-repression and neutrophil reprogramming

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1. scibot 11 Jun 2026
  
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  AB_2073556
  
  DOI: 10.64898/2026.06.01.725956
  
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biorxiv.org/content/10.64898/2026.06.01.725956v1
Jan 2026
54.241.53.176 54.241.53.176

1-s2.0-S2589004226001513-main-html.html

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1. scibot 27 Jan 2026
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.isci.2026.114776
  
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54.241.53.176/98fce87961b486739ffccb2301810ebb417a10a7/1-s2.0-S2589004226001513-main-html.html
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Extracellular vesicles from obese visceral adipose promote pancreatic cancer development and resistance to immune checkpoint blockade therapy

1
1. scibot 03 Dec 2025
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.cmet.2025.10.015
  
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sciencedirect.com:5037/science/article/pii/S1550413125004759
Oct 2025
54.241.53.176 54.241.53.176

1-s2.0-S2589004225021455-main-html.html

1
1. scibot 30 Oct 2025
  
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  AB_2073556
  
  DOI: 10.1016/j.isci.2025.113884
  
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54.241.53.176/84128bbe560a9c31c7bb36d713120503ae3762b4/1-s2.0-S2589004225021455-main-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

HLA-E and NKG2A Mediate Resistance to BCG Immunotherapy in Non-Muscle-Invasive Bladder Cancer

1
1. scibot 17 Oct 2025
  
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  AB_2073556
  
  DOI: 10.1101/2024.09.02.610816
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11398371/
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Targeting tumor monocyte-intrinsic PD-L1 by rewiring STING signaling and enhancing STING agonist therapy

1
1. scibot 11 Mar 2025
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.ccell.2025.02.014
  
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sciencedirect.com/science/article/pii/S1535610825000662
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Lymph node macrophages drive immune tolerance and resistance to cancer therapy by induction of the immune-regulatory cytokine IL-33

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1. scibot 07 Mar 2025
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.ccell.2025.02.017
  
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sciencedirect.com/science/article/pii/S1535610825000698
Feb 2025
52.53.155.43 52.53.155.43

cir-24-0484-html.html

1
1. scibot 20 Feb 2025
  
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  RRID:AB_2073556
  
  DOI: 10.1158/2326-6066.CIR-24-0484
  
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52.53.155.43/907147dca7b0350ae4d97a7f04ddc5ad1538a91e/cir-24-0484-html.html
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Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate onset of allergic airway neutrophilic disease

1
1. scibot 20 Feb 2025
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.celrep.2025.115294
  
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sciencedirect.com/science/article/pii/S2211124725000658
Jan 2025
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MFGE8 induces anti-PD-1 therapy resistance by promoting extracellular vesicle sorting of PD-L1

1
1. scibot 23 Jan 2025
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.xcrm.2024.101922
  
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sciencedirect.com/science/article/pii/S2666379124006931
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MerTK+ macrophages promote melanoma progression and immunotherapy resistance through AhR-ALKAL1 activation

1
1. scibot 08 Oct 2024
  
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  RRID:AB_2073556
  
  DOI: 10.1126/sciadv.ado8366
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11451552/
aacrjournals.org aacrjournals.org

A MyD88/IL-1R axis regulates PD-1 expression on tumor-associated macrophages and sustains their immunosuppressive function in melanoma

1
1. scibot 02 Oct 2024
  
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  RRID:AB_2073556
  
  DOI: 10.1158/0008-5472.CAN-20-3510
  
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aacrjournals.org/cancerres/article/81/9/2358/670580/A-MyD88-IL1R-Axis-Regulates-PD-1-Expression-on
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Macrophage-mediated myelin recycling fuels brain cancer malignancy

1
1. scibot 02 Oct 2024
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.cell.2024.07.030
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11429458/
Sep 2024
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Tumour-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signalling.

1
1. scibot 25 Sep 2024
  
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  AB_2073556
  
  DOI: 10.1016/j.isci.2024.110701
  
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sciencedirect.com/science/article/pii/S2589004224019266
Jul 2024
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Primary nasal influenza infection rewires tissue-scale memory response dynamics

1
1. scibot 18 Jul 2024
  
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  AB_2073556
  
  DOI: 10.1016/j.immuni.2024.06.005
  
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sciencedirect.com/science/article/pii/S107476132400311X
May 2024
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IL-7-primed bystander CD8 tumor-infiltrating lymphocytes optimize the antitumor efficacy of T cell engager immunotherapy

1
1. scibot 14 May 2024
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.xcrm.2024.101567
  
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sciencedirect.com/science/article/pii/S2666379124002593
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Disruption of CD47-SIRPα signalling restores inflammatory function in tumour-associated myeloid derived suppressor cells

1
1. scibot 11 Apr 2024
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.isci.2024.109546
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10993187/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas

1
1. scibot 15 Feb 2024
  
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  RRID:AB_2073556
  
  DOI: 10.1158/2767-9764.CRC-23-0399
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10863487/
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Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor

1
1. scibot 06 Feb 2024
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.chembiol.2024.01.002
  
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sciencedirect.com/science/article/pii/S2451945624000382
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Cell-intrinsic PD-L1 ablation sustains effector CD8+ T cell responses and promotes antitumor T cell therapy

1
1. scibot 02 Feb 2024
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.celrep.2024.113712
  
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sciencedirect.com/science/article/pii/S2211124724000408
Jul 2023
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Enhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors

2
1. scibot 08 Jul 2023
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.celrep.2023.112764
  
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2. scibot 08 Jul 2023
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.celrep.2023.112764
  
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sciencedirect.com/science/article/pii/S2211124723007751
May 2023
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cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity

1
1. scibot 11 May 2023
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.immuni.2023.04.005
  
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sciencedirect.com/science/article/pii/S1074761323001735
Apr 2023
www.nature.com www.nature.com

Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy

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1. scibot 11 Apr 2023
  
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  RRID:AB_2073556
  
  DOI: 10.1038/s41467-023-37617-3
  
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nature.com/articles/s41467-023-37617-3
Mar 2023
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Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment

1
1. scibot 16 Mar 2023
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.ccell.2023.02.005
  
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sciencedirect.com/science/article/pii/S1535610823000338
www.science.org www.science.org

Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy

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1. scibot 09 Mar 2023
  
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  RRID:AB_2073556
  
  DOI: 10.1126/sciimmunol.add8005
  
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science.org/doi/10.1126/sciimmunol.add8005
Jan 2023
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Immunoediting instructs tumor metabolic reprogramming to support immune evasion

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1. scibot 04 Jan 2023
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.cmet.2022.12.003
  
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sciencedirect.com/science/article/pii/S155041312200540X
Sep 2022
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Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity

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1. scibot 16 Sep 2022
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.ccell.2022.08.014
  
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sciencedirect.com/science/article/pii/S1535610822003786
Jun 2022
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Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity

1
1. scibot 15 Jun 2022
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.immuni.2022.05.012
  
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sciencedirect.com/science/article/pii/S1074761322002321
May 2022
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Mitochondrial damage-associated molecular patterns trigger arginase-dependent lymphocyte immunoregulation

1
1. scibot 26 May 2022
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.celrep.2022.110847
  
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sciencedirect.com/science/article/pii/S2211124722006209
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Tumor-induced erythroid precursor-differentiated myeloid cells mediate immunosuppression and curtail anti-PD-1/PD-L1 treatment efficacy

1
1. scibot 20 May 2022
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.ccell.2022.04.018
  
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sciencedirect.com/science/article/pii/S1535610822002112
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Antigen presentation safeguards the integrity of the hematopoietic stem cell pool

1
1. scibot 06 May 2022
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.stem.2022.04.007
  
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sciencedirect.com/science/article/pii/S1934590922001606
Jan 2022
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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells

1
1. scibot 26 Jan 2022
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.ccell.2021.12.009
  
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sciencedirect.com/science/article/pii/S1535610821006620
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Cellular and humoral functional responses after BNT162b2 mRNA vaccination differ longitudinally between naive and subjects recovered from COVID-19

1
1. scibot 05 Jan 2022
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.celrep.2021.110235
  
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sciencedirect.com/science/article/pii/S2211124721017447
Sep 2021
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A mouse model for the study of anti-tumor T cell responses in Kras-driven lung adenocarcinoma

1
1. scibot 17 Sep 2021
  
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  RRID:AB_2073556
  
  DOI: 10.1016/j.crmeth.2021.100080
  
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sciencedirect.com/science/article/pii/S2667237521001351
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Endogenous Retrovirus Envelope as a Tumor-Associated Immunotherapeutic Target in Murine Osteosarcoma

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1. scibot 21 Jul 2021
  
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  DOI: 10.1016/j.isci.2021.102759
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8267546/
Jun 2021
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Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

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1. scibot 25 Jun 2021
  
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  DOI: 10.1016/j.cell.2021.05.038
  
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sciencedirect.com/science/article/pii/S0092867421006905
Apr 2021
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NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion

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1. scibot 30 Apr 2021
  
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  DOI: 10.1016/j.cmet.2020.10.021
  
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sciencedirect.com/science/article/pii/S1550413120305544
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Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade

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1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.molcel.2021.03.037
  
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sciencedirect.com/science/article/pii/S109727652100232X
Sep 2020
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Rewilding Nod2 and Atg16l1 Mutant Mice Uncovers Genetic and Environmental Contributions to Microbial Responses and Immune Cell Composition

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1. scibot 25 Sep 2020
  
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  DOI: 10.1016/j.chom.2020.03.001
  
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cell.com/cell-host-microbe/fulltext/S1931-3128(20)30124-4
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Altered Immunity of Laboratory Mice in the Natural Environment Is Associated with Fungal Colonization

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1. scibot 23 Sep 2020
  
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  DOI: 10.1016/j.chom.2020.02.015
  
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The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection

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1. scibot 16 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107827
  
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Jan 2020
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Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.07.065
  
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sciencedirect.com/science/article/pii/S2211124719309696
Nov 2018
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LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade

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1. scibot 05 Nov 2018
  
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Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation

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1. scibot 05 Nov 2018
  
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