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Spatial immune profiling defines a subset of human gliomas with functional tertiary lymphoid structures

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1. scibot 22 Oct 2025
  
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  DOI: 10.1016/j.immuni.2025.09.018
  
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Sep 2025
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GALNT7 stratifies dMMR/MSI colorectal cancer into distinct molecular subsets associated with prognosis and PD-L1 expression

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  DOI: 10.1158/2767-9764.CRC-25-0270
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12412012/
Aug 2025
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AI-driven multimodal algorithm predicts immunotherapy and targeted therapy outcomes in clear cell renal cell carcinoma

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  DOI: 10.1016/j.xcrm.2025.102299
  
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HMGA2 Expression Predicts Subtype, Survival, and Treatment Outcome in Pancreatic Ductal Adenocarcinoma

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1. scibot 19 Aug 2025
  
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  DOI: 10.1158/1078-0432.CCR-24-2200
  
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inline-supplementary-material-2-html.html

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  DOI: 10.1136/jitc-2025-011818
  
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52.53.155.43/100e14b90da09131bf5c9cf9d4efd569ae25716b/inline-supplementary-material-2-html.html
Jul 2025
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Methodology for generating chorioallantoic membrane patient-derived xenograft (CAM-PDX) models of pleural mesothelioma and performing preclinical imaging for the translation of cancer studies and drug screening

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1. scibot 02 Jul 2025
  
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  DOI: 10.12688/f1000research.163596.1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12188182/
Jun 2025
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Impact of the tumor immune contexture in microsatellite-stable metastatic colorectal cancer treated with avelumab, cetuximab, and irinotecan

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1. scibot 25 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102201
  
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A Phase I, First-in-Human, Dose-Escalation, Expansion Trial of Cytokine-Encoding Synthetic mRNA Mixture Alone or with Cemiplimab in Advanced Solid Tumors

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1. scibot 17 Jun 2025
  
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  DOI: 10.1158/1078-0432.ccr-25-0419
  
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52.53.155.43/095f1297dc44b7c13374b7a22bd6385cbe7ad75d/PDF-html.html
Apr 2025
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Phase 2 trial of perioperative chemo-immunotherapy for gastro-esophageal adenocarcinoma: The role of M2 macrophage landscape in predicting response

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1. scibot 17 Apr 2025
  
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  DOI: 10.1016/j.xcrm.2025.102045
  
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1. scibot 02 Apr 2025
  
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52.53.155.43/474b111b753cd0d77d3a2f1634905ce9847379d5/PDF-html.html
Mar 2025
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Safety and Efficacy of Copanlisib in Combination with Nivolumab: A Phase Ib Study in Patients with Advanced Solid Tumors

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1. scibot 20 Mar 2025
  
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  DOI: 10.1158/2767-9764.CRC-24-0407
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11907410/
Feb 2025
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Platinum-based chemotherapy induces opposing effects on immunotherapy response-related spatial and stromal biomarkers in the bladder cancer microenvironment

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1. scibot 13 Feb 2025
  
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  DOI: 10.1158/1078-0432.CCR-24-0724
  
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aacrjournals.org/clincancerres/article/30/18/4227/747456/Platinum-Based-Chemotherapy-Induces-Opposing
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Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity

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1. scibot 11 Feb 2025
  
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  DOI: 10.1016/j.ccell.2025.01.004
  
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Disrupting AGR2/IGF1 paracrine and reciprocal signaling for pancreatic cancer therapy

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1. scibot 07 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2024.101927
  
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sciencedirect.com/science/article/pii/S2666379124006980
Jan 2025
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The Tumor Immune Microenvironment and Therapeutic Efficacy of Trastuzumab Deruxtecan in Gastric Cancer

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1. scibot 16 Jan 2025
  
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  DOI: 10.1158/2767-9764.CRC-24-0302
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11729160/
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PDF-html.html

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1. scibot 10 Jan 2025
  
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  DOI: 10.1158/2326-6066.cir-24-0421
  
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52.53.155.43/aca28ffb04c86b6d09a1d2d72019bac2f6589e6e/PDF-html.html
Dec 2024
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Atezolizumab, bevacizumab, pemetrexed and platinum for EGFR‐mutant NSCLC patients after EGFR TKI failure: A phase II study with immune cell profile analysis

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1. scibot 27 Dec 2024
  
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  DOI: 10.1002/ctm2.70149
  
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crc-24-0302-html.html

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1. scibot 19 Dec 2024
  
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  AB_2075537
  
  DOI: 10.1158/2767-9764.crc-24-0302
  
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52.53.155.43/b33b46a18df1167439c20d268efee10f1a3d925f/crc-24-0302-html.html
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Skin immune-mesenchymal interplay within tertiarylymphoid structures promotes autoimmunepathogenesis in hidradenitis suppurativa

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1. scibot 12 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.010
  
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Lurbinectedin sensitizes PD-L1 blockade therapy by activating STING-IFN signaling in small-cell lung cancer

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1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.xcrm.2024.101852
  
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Nov 2024
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Fibroblastic reticular cells generate protective intratumoral T cell environments in lung cancer

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1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.cell.2024.10.042
  
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Aug 2024
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Clinical implications and molecular features of extracellular matrix networks in soft tissue sarcomas

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1. scibot 18 Aug 2024
  
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  DOI: 10.1158/1078-0432.CCR-23-3960
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11292195/
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Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing

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1. scibot 02 Aug 2024
  
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  DOI: 10.1016/j.cell.2020.07.017
  
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cell.com/cell/fulltext/S0092-8674(20)30882-5
Jul 2024
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Benign prostatic hyperplasia nodules in patients treated with celecoxib and/or finasteride have reduced levels of NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, a mitochondrial protein essential for efficient function of the electron transport chain

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1. scibot 19 Jul 2024
  
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  DOI: 10.1002/pros.24766
  
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Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.cell.2024.06.012
  
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May 2024
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FDG PET/CT Imaging 1 Week after a Single Dose of Pembrolizumab Predicts Treatment Response in Patients with Advanced Melanoma

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1. scibot 23 May 2024
  
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  DOI: 10.1158/1078-0432.CCR-23-2390
  
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aacrjournals.org/clincancerres/article/30/9/1758/743135/FDG-PET-CT-Imaging-1-Week-after-a-Single-Dose-of
Apr 2024
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Versican associates with tumour immune phenotype and limits T cell trafficking via chondroitin sulfate

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1. scibot 11 Apr 2024
  
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  DOI: 10.1158/2767-9764.CRC-23-0548
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10989462/
Feb 2024
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PD-1 Expression on Intratumoral Regulatory T Cells is Associated with Lack of Benefit from Anti-PD-1 Therapy in Metastatic Clear Cell Renal Cell Carcinoma Patients

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  DOI: 10.1158/1078-0432.CCR-23-2274
  
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aacrjournals.org/clincancerres/article/30/4/803/734199/PD-1-Expression-on-Intratumoral-Regulatory-T-Cells
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Proteogenomic characterization of primary colorectal cancer and metastatic progression identifies proteome-based subtypes and signatures

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  DOI: 10.1016/j.celrep.2024.113810
  
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Immune heterogeneity in small-cell lung cancer and vulnerability to immune checkpoint blockade

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  DOI: 10.1016/j.ccell.2024.01.010
  
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A human stomach cell type transcriptome atlas

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1. scibot 15 Feb 2024
  
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  DOI: 10.1186/s12915-024-01812-5
  
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link.springer.com/article/10.1186/s12915-024-01812-5
Dec 2023
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The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer

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  DOI: 10.1016/j.immuni.2023.11.002
  
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Anti-PD-1 immunotherapy with androgen deprivation therapy induces robust immune infiltration in metastatic castration-sensitive prostate cancer

1
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Spatial metabolomics identifies distinct tumor-specific and stroma-specific subtypes in patients with lung squamous cell carcinoma

1
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Sep 2023
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Understanding yellow fever-associated myocardial injury: an autopsy study

1
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Activin A-mediated polarization of cancer-associated fibroblasts and macrophages confers resistance to checkpoint immunotherapy in skin cancer

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Aug 2023
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Activating Inducible T cell Co-stimulator (ICOS) yields anti-tumor activity alone and in combination with anti-PD-1 checkpoint blockade

3
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Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer

2
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  DOI: 10.1016/j.cell.2023.07.004
  
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52.53.155.43 52.53.155.43

crc-22-0293-html.html

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Intratumoral NKp46+ natural killer cells are spatially distanced from T and MHC-I+ cells with prognostic implications in soft tissue sarcoma

1
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Circulating and intratumoral immune determinants of response to atezolizumab plus bevacizumab in patients with variant histology or sarcomatoid renal cell carcinoma

1
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Jul 2023
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Multi-scale spatial modeling of immune cell distributions enables survival prediction in primary central nervous system lymphoma

1
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SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck

1
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ccr-23-0219-html.html

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May 2023
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Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microenvironment

1
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Apr 2023
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Addition of losartan to FOLFIRINOX and chemoradiation reduces immunosuppression-associated genes, Tregs and FOXP3+ cancer cells in locally advanced pancreatic cancer

1
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A Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear Cell Renal Cell Carcinoma

1
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  DOI: 10.1158/2159-8290.CD-21-0925
  
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Lineage tracing reveals clonal progenitors and long-term persistence of tumor-specific T cells during immune checkpoint blockade

1
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A human stomach cell type transcriptome atlas

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  DOI: 10.1101/2023.01.10.520700
  
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Neoadjuvant Intravenous Oncolytic Vaccinia Virus Therapy Promotes Anticancer Immunity in Patients

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  DOI: 10.1158/2326-6066.CIR-21-0171
  
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Dec 2022
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Differential expression of CD8 defines phenotypically distinct cytotoxic T cells in cancer and multiple sclerosis

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  DOI: 10.1002/ctm2.1068
  
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Nov 2022
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Transcriptomic Correlates of Tumor Cell PD-L1 Expression and Response to Nivolumab Monotherapy in Metastatic Clear Cell Renal Cell Carcinoma

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Sep 2022
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Defining the Immune Checkpoint Landscape in Human Colorectal Cancer Highlights the Relevance of the TIGIT/CD155 Axis for Optimizing Immunotherapy

1
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Aug 2022
52.53.155.43 52.53.155.43

cd-21-0925-html.html

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Personalized neoantigen vaccine NEO-PV-01 with chemotherapy and anti-PD-1 as first-line treatment for non-squamous non-small cell lung cancer

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Multiregional single-cell proteogenomic analysis of ccRCC reveals cytokine drivers of intratumor spatial heterogeneity

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  DOI: 10.1016/j.celrep.2022.111180
  
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Jun 2022
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The immune cell atlas of human neuroblastoma

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May 2022
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Mutual exclusivity of ESR1 and TP53 mutations in endocrine resistant metastatic breast cancer

1
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ncbi.nlm.nih.gov/pmc/articles/PMC9090919/
Apr 2022
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Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells

2
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  DOI: 10.1016/j.ccell.2022.03.008
  
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  DOI: 10.1016/j.ccell.2022.03.008
  
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Feb 2022
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Steroid hormone receptor and infiltrating immune cell status reveals therapeutic vulnerabilities of ESR1 mutant breast cancer.

1
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  DOI: 10.1158/0008-5472.CAN-20-1200
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7854521/
Jan 2022
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Integrative clinical and molecular characterization of translocation renal cell carcinoma

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  DOI: 10.1016/j.celrep.2021.110190
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9127595/
Dec 2021
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Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells

1
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  DOI: 10.1172/jci.insight.151797
  
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insight.jci.org/articles/view/151797
Sep 2021
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Immunoregulated insulitis and slow-progressing type 1 diabetes after duodenopancreatectomy

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  DOI: 10.1007/s00125-021-05563-8
  
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Aug 2021
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1. scibot 09 Aug 2021
  
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  RRID:AB_2075537
  
  DOI: 10.1016/j.cell.2018.10.014
  
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sciencedirect.com/science/article/pii/S0092867418313229
Jul 2021
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Untitled document

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1. scibot 31 Jul 2021
  
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  DOI: 10.1016/j.ccell.2018.11.003
  
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sciencedirect.com/science/article/pii/S1535610818305245
May 2021
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An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells

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1. scibot 06 May 2021
  
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  DOI: 10.1016/j.immuni.2020.06.016
  
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Apr 2021
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Oncolytic virotherapy-mediated anti-tumor response: a single-cell perspective

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1. scibot 22 Apr 2021
  
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  DOI: 10.1016/j.ccell.2020.12.022
  
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sciencedirect.com/science/article/pii/S153561082030670X
Mar 2021
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Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer

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1. scibot 08 Mar 2021
  
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  DOI: 10.1016/j.ccell.2020.12.001
  
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sciencedirect.com/science/article/pii/S1535610820306085
Jan 2021
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Multi-organ proteomic landscape of COVID-19 autopsies

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1. scibot 28 Jan 2021
  
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  RRID:AB_2075537
  
  DOI: 10.1016/j.cell.2021.01.004
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7794601/
Sep 2020
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Dithranol targets keratinocytes, their crosstalk with neutrophils and inhibits the IL-36 inflammatory loop in psoriasis

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1. scibot 26 Sep 2020
  
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  DOI: 10.7554/eLife.56991
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7266641/
cancerimmunolres.aacrjournals.org cancerimmunolres.aacrjournals.org

Self-maintaining CD103+ cancer-specific T cells are highly energetic with rapid cytotoxic and effector responses

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1. scibot 23 Sep 2020
  
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  RRID:AB_2075537
  
  DOI: 10.1158/2326-6066.CIR-19-0554
  
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cancerimmunolres.aacrjournals.org/content/8/2/203
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Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade

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1. scibot 23 Sep 2020
  
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  RRID:AB_2075537
  
  DOI: 10.1016/j.immuni.2019.01.006
  
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cell.com/immunity/abstract/S1074-7613(19)30029-9
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Human pDCs Are Superior to cDC2s in Attracting Cytolytic Lymphocytes in Melanoma Patients Receiving DC Vaccination

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1. scibot 11 Sep 2020
  
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  DOI: 10.1016/j.celrep.2019.12.096
  
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Integrated Multi-omic Analysis of Esthesioneuroblastomas Identifies Two Subgroups Linked to Cell Ontogeny

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1. scibot 04 Sep 2020
  
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  Mouse monoclonal CD8 clone 144B
  
  DOI: 10.1016/j.celrep.2018.09.047
  
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sciencedirect.com/science/article/pii/S221112471831492X
Jan 2020
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.01.006
  
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Nov 2018
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Evolution of Metastases in Space and Time under Immune Selection

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1. scibot 05 Nov 2018
  
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Untitled document

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1. scibot 05 Nov 2018
  
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Untitled document

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ncbi.nlm.nih.gov/pmc/articles/PMC5956280/
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Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1535610818301752
Nov 2017
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Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses

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1. scibot 08 Nov 2017
  
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  Anti-Human CD8 (clone C8/144b)
  
  Curator: @kaitlinsung
  
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sciencedirect.com/science/article/pii/S0092867417304270

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