17 Matching Annotations
  1. May 2026
  2. www.sciencedirect.com www.sciencedirect.com
    Accumulated sotorasib-bound KRASG12C reactivates the MAPK pathway and drives sotorasib resistance via the DHX9-RAC1-PAK1 axis
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    sciencedirect.com/science/article/pii/S221112472600416X
  3. Apr 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol to identify covalent inhibitors targeting RhoA Cys16
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    pmc.ncbi.nlm.nih.gov/articles/PMC13092739/
  5. Nov 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FGD3 mediates lytic cell death, enhancing efficacy and immunogenicity of chemotherapy agents in breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12613929/
  7. Sep 2025
  8. www.sciencedirect.com www.sciencedirect.com
    A covalent inhibitor targeting Cys16 on RhoA in colorectal cancer
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    sciencedirect.com/science/article/pii/S2451945625002557
  9. Apr 2025
  10. www.sciencedirect.com www.sciencedirect.com
    ARHGAP12 suppresses F-actin assembly to control epithelial tight junction mechanics and paracellular leak pathway permeability
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    sciencedirect.com/science/article/pii/S2211124725002827
  11. Mar 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12035956/
  13. Dec 2024
  14. www.sciencedirect.com www.sciencedirect.com
    P-cadherin mechanoactivates tumor-mesothelium metabolic coupling to promote ovarian cancer metastasis
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    sciencedirect.com/science/article/pii/S2211124724014475
  15. May 2024
  16. journals.asm.org journals.asm.org
    Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum
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    journals.asm.org/doi/10.1128/mbio.00299-24
  17. Apr 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum
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    ncbi.nlm.nih.gov/pmc/articles/PMC11005342/
  19. Mar 2024
  20. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  21. Jul 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Srgap2 suppression ameliorates retinal ganglion cell degeneration in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10328280/
  23. Jul 2022
  24. www.sciencedirect.com www.sciencedirect.com
    Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover
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    sciencedirect.com/science/article/pii/S1534580722004518
  25. Apr 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer
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    sciencedirect.com/science/article/pii/S221112472200393X
  27. Oct 2021
  28. academic.oup.com academic.oup.com
    Inhibition of miR-29 activity in the myeloid lineage increases response to calcitonin and trabecular bone volume in mice
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    academic.oup.com/endo/article/162/10/bqab135/6311858
  29. Aug 2021
  30. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    onlinelibrary.wiley.com/doi/full/10.1002/hipo.23047
  31. Jul 2021
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An RNAi screen of Rho signalling networks identifies RhoH as a regulator of Rac1 in prostate cancer cell migration
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    ncbi.nlm.nih.gov/pmc/articles/PMC5840776/