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Harnessing senolytics and PARP inhibition to expand the antitumor activity of CDK4/6 inhibitors in prostate cancer

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1. scibot 07 Apr 2026
  
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  DOI: 10.1158/1535-7163.MCT-24-0903
  
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aacrjournals.org/mct/article/24/12/1959/768323/Harnessing-Senolytics-and-PARP-Inhibition-to
Mar 2026
www.biorxiv.org www.biorxiv.org

PRMT5 is Frequently Upregulated and a Potential Therapeutic Target in MTAP-deficient Malignant Peripheral Nerve Sheath Tumors

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1. scibot 19 Mar 2026
  
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  DOI: 10.64898/2026.03.09.710638
  
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biorxiv.org/content/10.64898/2026.03.09.710638v1
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting the LHX1-LDB1 Complex Restores STING-dependent Senescence Surveillance and Inhibits Head and Neck Cancer Progression

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1. scibot 30 Jan 2026
  
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  DOI: 10.7150/ijbs.123790
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12836506/
Nov 2025
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Trilaciclib triggers a neutrophil-related immune response and sensitizes non-small cell lung cancer to anti-PD-1 therapy

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1. scibot 06 Nov 2025
  
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  DOI: 10.1016/j.xcrm.2025.102434
  
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sciencedirect.com/science/article/pii/S2666379125005075
Sep 2025
52.53.155.43 52.53.155.43

1-s2.0-S0531556525002098-main-html.html

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.exger.2025.112880
  
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52.53.155.43/5584957b76ac485235fd64ade889b71206fc7ad5/1-s2.0-S0531556525002098-main-html.html
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Shenyuan granules improve cellular senescence through Klotho-mediated p16/p21 signaling pathway in diabetic kidney disease

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1. scibot 16 Aug 2025
  
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  DOI: 10.3389/fmed.2025.1627412
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12350460/
Feb 2025
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Hepatic sphingomyelin phosphodiesterase 3 promotes steatohepatitis by disrupting membrane sphingolipid metabolism

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1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.cmet.2025.01.016
  
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sciencedirect.com/science/article/pii/S1550413125000166
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Synonymous mutations promote tumorigenesis by disrupting m6A-dependent mRNA metabolism

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1. scibot 14 Feb 2025
  
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  DOI: 10.1016/j.cell.2025.01.026
  
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sciencedirect.com/science/article/pii/S0092867425000959
Nov 2024
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Autophagy-dependent splicing control directs translation toward inflammation during senescence

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1. scibot 16 Nov 2024
  
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  DOI: 10.1016/j.devcel.2024.10.008
  
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sciencedirect.com/science/article/pii/S1534580724006270
52.53.155.43 52.53.155.43

can-24-1817-html.html

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1. scibot 14 Nov 2024
  
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  DOI: 10.1158/0008-5472.can-24-1817
  
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52.53.155.43/65dca824591f5654591dc592fd6476e0cd35e8bf/can-24-1817-html.html
Sep 2024
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A TBK1-independent primordial function of STING in lysosomal biogenesis

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1. scibot 25 Sep 2024
  
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  AB_2078303
  
  DOI: 10.1016/j.molcel.2024.08.026
  
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sciencedirect.com/science/article/pii/S1097276524007032
Jul 2024
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 18 Jul 2024
  
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  RRID:AB_2078303
  
  DOI: 10.1111/bph.16494
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16494
Apr 2024
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Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome

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1. scibot 16 Apr 2024
  
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  RRID:AB_2078303
  
  DOI: 10.1016/j.celrep.2024.114111
  
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sciencedirect.com/science/article/pii/S221112472400439X
Jan 2024
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Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells

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1. scibot 25 Jan 2024
  
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  DOI: 10.1016/j.devcel.2024.01.002
  
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sciencedirect.com/science/article/pii/S1534580724000029
Nov 2023
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Downregulation of ALKBH5 rejuvenates aged human mesenchymal stem cells and enhances their therapeutic efficacy in myocardial infarction

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1. scibot 18 Nov 2023
  
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  DOI: 10.1096/fj.202301292R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202301292R
Apr 2023
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CX3CR1hi macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue

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1. scibot 22 Apr 2023
  
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  RRID:AB_2078303
  
  DOI: 10.1016/j.celrep.2023.112424
  
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sciencedirect.com/science/article/pii/S2211124723004357
Jan 2023
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PKR deficiency delays vascular aging via inhibiting GSDMD-mediated endothelial cell hyperactivation

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1. scibot 12 Jan 2023
  
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  RRID:AB_2078303
  
  DOI: 10.1016/j.isci.2022.105909
  
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2. scibot 12 Jan 2023
  
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  RRID:AB_2078303
  
  DOI: 10.1016/j.isci.2022.105909
  
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sciencedirect.com/science/article/pii/S2589004222021824
Aug 2022
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Increasing cell size remodels the proteome and promotes senescence

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1. scibot 22 Aug 2022
  
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  DOI: 10.1016/j.molcel.2022.07.017
  
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sciencedirect.com/science/article/pii/S1097276522007134
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Genetic impairment of succinate metabolism disrupts bioenergetic sensing in adrenal neuroendocrine cancer

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1. scibot 17 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111218
  
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sciencedirect.com/science/article/pii/S221112472201035X
Nov 2021
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Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease

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1. scibot 09 Nov 2021
  
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  DOI: 10.1016/j.isci.2021.103327
  
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sciencedirect.com/science/article/pii/S2589004221012967
Oct 2021
mct.aacrjournals.org mct.aacrjournals.org

Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma

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1. scibot 20 Oct 2021
  
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  DOI: 10.1158/1535-7163.MCT-20-1126
  
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mct.aacrjournals.org/content/20/10/2049
Jul 2021
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Targeting senescent cells improves functional recovery after spinal cord injury

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1. scibot 07 Jul 2021
  
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  DOI: 10.1016/j.celrep.2021.109334
  
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sciencedirect.com/science/article/pii/S2211124721007105
Dec 2020
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HIV TAT-mediated microglial senescence: Role of SIRT3-dependent mitochondrial oxidative stress

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1. scibot 30 Dec 2020
  
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  Rabbit polyclonal anti-p16
  
  DOI: 10.1016/j.redox.2020.101843
  
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sciencedirect.com/science/article/pii/S221323172031048X
Jan 2020
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 13 Jan 2020
  
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  RRID:AB_2078303
  
  DOI: 10.1111/bph.14754
  
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  RRID:AB_2078303 RRIDCUR:Validated
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bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.14754