Hypothesis

20 Matching Annotations

Jan 2026
www.nature.com www.nature.com

CDK2 inhibitor BLU-222 synergizes with CDK4/6 inhibitors in drug resistant breast cancers through p21/p27 induction

1
1. scibot 27 Jan 2026
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1038/s41467-025-67865-4
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

nature.com/articles/s41467-025-67865-4
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PatientProfiler: building patient-specific signaling models from proteogenomic data

1
1. scibot 05 Dec 2025
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1038/s44320-025-00160-y
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12672659/
Nov 2025
www.sciencedirect.com www.sciencedirect.com

CDK7 is a novel therapeutic target in fibrolamellar carcinoma

1
1. scibot 22 Nov 2025
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1016/j.isci.2025.113925
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004225021868
May 2025
www.sciencedirect.com www.sciencedirect.com

Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target

1
1. scibot 17 May 2025
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1016/j.ccell.2025.04.014
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610825001734
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation–Induced Apoptosis

1
1. scibot 04 Apr 2025
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1158/1078-0432.CCR-24-2548
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11964295/
Feb 2025
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 07 Feb 2025
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1158/1078-0432.ccr-24-2548
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

52.53.155.43/f141eddf8d6ed9d4f64a9be0f6055059836b8d11/PDF-html.html
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Selective CDK7 inhibition suppresses cell cycle progression and MYC signaling while enhancing apoptosis in therapy-resistant estrogen receptor positive breast cancer

1
1. scibot 03 May 2024
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1158/1078-0432.CCR-23-2975
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11061603/
Nov 2023
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers

1
1. scibot 03 Nov 2023
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1158/1078-0432.CCR-23-0103
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

pubmed.ncbi.nlm.nih.gov/37279095/
Oct 2023
52.53.155.43 52.53.155.43

ccr-23-0103-html.html

1
1. scibot 07 Oct 2023
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1158/1078-0432.ccr-23-0103
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
Aug 2023
52.53.155.43 52.53.155.43

ccr-23-0103-html.html

1
1. scibot 11 Aug 2023
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1158/1078-0432.ccr-23-0103
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
www.sciencedirect.com www.sciencedirect.com

FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth

1
1. scibot 03 Aug 2023
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1016/j.celrep.2023.112886
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723008975
Jul 2023
52.53.155.43 52.53.155.43

ccr-23-0103-html.html

1
1. scibot 08 Jul 2023
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1158/1078-0432.ccr-23-0103
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity

1
1. scibot 02 Jun 2023
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1016/j.cell.2023.05.013
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867423005329
Jan 2023
www.sciencedirect.com www.sciencedirect.com

Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling

1
1. scibot 24 Jan 2023
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1016/j.celrep.2023.112031
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723000426
Jul 2022
www.sciencedirect.com www.sciencedirect.com

A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase

1
1. scibot 12 Jul 2022
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1016/j.devcel.2022.06.008
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580722004488
Jan 2020
www.sciencedirect.com www.sciencedirect.com

CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1016/j.ccell.2019.11.003
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2078685

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610819305239
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2078685
  
  DOI: 10.1016/j.chembiol.2019.02.012
  
  Resource: (Cell Signaling Technology Cat# 2561, RRID:AB_2078685)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2078685
  
  What is this?
  
  RRID:AB_2078685 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2078685

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945619300674
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Adaptive Fibrogenic Reprogramming of Osteosarcoma Stem Cells Promotes Metastatic Growth

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2078685
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2561S, RRID:AB_2078685)
  
  SciCrunch record: RRID:AB_2078685
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2078685
Visit annotations in context

Tags

RRID:AB_2078685

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124718310453
academic.oup.com academic.oup.com

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  AB_2078685
  
  Curator: @evieth
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2561S, RRID:AB_2078685)
  
  SciCrunch record: RRID:AB_2078685
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2078685 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2078685

Annotators

scibot

URL

academic.oup.com/biolreprod/article/98/1/102/4638519
academic.oup.com academic.oup.com

Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice

1
1. scibot 05 Nov 2018
  
  in Public
  
  AB_2078685
  
  Curator: @evieth
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2561S, RRID:AB_2078685)
  
  SciCrunch record: RRID:AB_2078685
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2078685 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2078685

Annotators

scibot

URL

academic.oup.com/biolreprod/advance-article/doi/10.1093/biolre/iox150/4638519