13 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Distinct effects of sacituzumab govitecan and berzosertib on DNA damage response in ovarian cancer
    1
    1. scibot 15 Nov 2024
      RRID:AB_2080323

      DOI: 10.1016/j.isci.2024.111283

      Resource: (Cell Signaling Technology Cat# 2349, RRID:AB_2080323)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S2589004224025082
  3. Sep 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Transient splicing inhibition causes persistent DNA damage and chemotherapy vulnerability in triple-negative breast cancer
    1
    1. scibot 17 Sep 2024
      AB_2080323

      DOI: 10.1016/j.celrep.2024.114751

      Resource: (Cell Signaling Technology Cat# 2349, RRID:AB_2080323)

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    sciencedirect.com/science/article/pii/S2211124724011021
  5. Jun 2024
  6. www.cell.com www.cell.com
    CHK1 inhibitor SRA737 is active in PARP inhibitor resistant and CCNE1 amplified ovarian cancer
    1
    1. scibot 29 Jun 2024
      RRID:AB_2080323

      DOI: 10.1016/j.isci.2024.109978

      Resource: (Cell Signaling Technology Cat# 2349, RRID:AB_2080323)

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    cell.com/iscience/abstract/S2589-0042(24)01200-8
  7. Dec 2023
  8. www.sciencedirect.com www.sciencedirect.com
    PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
    1
    1. scibot 20 Dec 2023
      RRID:AB_2080323

      DOI: 10.1016/j.xcrm.2023.101326

      Resource: (Cell Signaling Technology Cat# 2349, RRID:AB_2080323)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S2666379123005438
  9. May 2023
  10. www.sciencedirect.com www.sciencedirect.com
    Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway
    1
    1. scibot 17 May 2023
      RRID:AB_2080323

      DOI: 10.1016/j.cell.2023.04.026

      Resource: (Cell Signaling Technology Cat# 2349, RRID:AB_2080323)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S0092867423004221
  11. Nov 2022
  12. academic.oup.com academic.oup.com
    Multiple-low-dose therapy: effective killing of high-grade serous ovarian cancer cells with ATR and CHK1 inhibitors
    1
    1. scibot 15 Nov 2022
      RRID:AB_2080323

      DOI: 10.1093/narcan/zcac036

      Resource: (Cell Signaling Technology Cat# 2349, RRID:AB_2080323)

      Curator: @scibot

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    academic.oup.com/narcancer/article/4/4/zcac036/6825304
  13. Mar 2022
  14. www.sciencedirect.com www.sciencedirect.com
    Chk1 dynamics in G2 phase upon replication stress predict daughter cell outcome
    1
    1. scibot 04 Mar 2022
      RRID:AB_2080323

      DOI: 10.1016/j.devcel.2022.02.013

      Resource: (Cell Signaling Technology Cat# 2349, RRID:AB_2080323)

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    sciencedirect.com/science/article/pii/S153458072200079X
  15. Jan 2022
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 Screen Identifies DYRK1A as a Target for Radiotherapy Sensitization in Pancreatic Cancer
    1
    1. scibot 22 Jan 2022
      RRID:AB_2080323

      DOI: 10.3390/cancers14020326

      Resource: (Cell Signaling Technology Cat# 2349, RRID:AB_2080323)

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    ncbi.nlm.nih.gov/pmc/articles/PMC8773906/
  17. Aug 2021
  18. www.jbc.org www.jbc.org
    Inhibition of checkpoint kinase 1 following gemcitabine-mediated S phase arrest results in CDC7- and CDK2-dependent replication catastrophe
    1
    1. scibot 03 Aug 2021
      AB_2080323

      DOI: 10.1074/jbc.RA118.005231

      Resource: (Cell Signaling Technology Cat# 2349, RRID:AB_2080323)

      Curator: @scibot

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    jbc.org/content/294/6/1763.full
  19. May 2021
  20. www.sciencedirect.com www.sciencedirect.com
    TopBP1 assembles nuclear condensates to switch on ATR signaling
    1
    1. scibot 08 May 2021
      RRID:AB_2080323

      DOI: 10.1016/j.molcel.2020.12.049

      Resource: (Cell Signaling Technology Cat# 2349, RRID:AB_2080323)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S1097276520309916
  21. Jan 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A
    1
    1. scibot 27 Jan 2021
      RRID:AB_2080323

      DOI: 10.1016/j.celrep.2020.108680

      Resource: (Cell Signaling Technology Cat# 2349, RRID:AB_2080323)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:AB_2080323
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    sciencedirect.com/science/article/pii/S2211124720316697
  23. Jan 2020
  24. www.sciencedirect.com www.sciencedirect.com
    The SUMO Isopeptidase SENP6 Functions as a Rheostat of Chromatin Residency in Genome Maintenance and Chromosome Dynamics
    1
    1. scibot 13 Jan 2020
      RRID:AB_2080323

      DOI: 10.1016/j.celrep.2019.08.106

      Resource: (Cell Signaling Technology Cat# 2349, RRID:AB_2080323)

      Curator: @ethanbadger

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      RRID:AB_2080323 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719311684
  25. Nov 2017
  26. www.sciencedirect.com www.sciencedirect.com
    Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication
    1
    1. scibot 08 Nov 2017
      Rabbit polyclonal anti-Phospho-Chk1 (Ser296)Cell SignalingCat# 2349

      Curator: @Jmenke

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      (Cell Signaling Technology Cat# 2349, RRID:AB_2080323)

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      RRID:AB_2080323 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1097276517301727