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  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection
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    sciencedirect.com/science/article/pii/S2211124724004844
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adipocyte-Released Adipomes in Chagas Cardiomyopathy: Impact on Cardiac Metabolic and Immune Regulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11039351/
  4. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Caffeic acid does not protect human pancreatic β cells against stearic acid-induced ER stress and apoptosis
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  5. Apr 2024
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    The IRE1α-XBP1 arm of the unfolded protein response is a host factor activated in SARS-CoV-2 infection
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    sciencedirect.com/science/article/pii/S0925443924001820
  7. aacrjournals.org aacrjournals.org
    miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress
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    aacrjournals.org/mcr/article/22/4/360/741846/miR-217-Regulates-Normal-and-Tumor-Cell-Fate
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    Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding
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    nature.com/articles/s41593-024-01615-5
  9. Mar 2024
  10. www.sciencedirect.com www.sciencedirect.com
    A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders
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    sciencedirect.com/science/article/pii/S0925443924001200
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    Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders
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    sciencedirect.com/science/article/pii/S2211124724002286
  12. Feb 2024
  13. 52.53.155.43 52.53.155.43
    A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders
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    Ultrafine particulate matter pollution and dysfunction of endoplasmic reticulum Ca2+ store: A pathomechanism shared with amyotrophic lateral sclerosis motor neurons?
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    sciencedirect.com/science/article/pii/S0147651324001799
  15. 52.53.155.43 52.53.155.43
    Influenza A virus propagation requires the activation of the unfolded protein response and the accumulation of insoluble protein aggregates
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    1. scibot 09 Feb 2024
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  16. Dec 2023
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    Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic steatohepatitis
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    sciencedirect.com/science/article/pii/S2212877823001850
  18. Sep 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryptotanshinone is a candidate therapeutic agent for interstitial lung disease associated with a BRICHOS-domain mutation of SFTPC
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    1. scibot 17 Sep 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10494175/
  20. Aug 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10405072/
  22. Jul 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons
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    sciencedirect.com/science/article/pii/S221112472300757X
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    Bacterial effector restricts liquid-liquid phase separation of ZPR1 to antagonize host UPRER
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    sciencedirect.com/science/article/pii/S2211124723007118
  25. Jun 2023
  26. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.16074

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16074
  27. May 2023
  28. academic.oup.com academic.oup.com
    Berberine ameliorates obesity by inducing GDF15 secretion by brown adipocytes
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    1. scibot 12 May 2023
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      DOI: 10.1210/endocr/bqad035

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    academic.oup.com/endo/article/164/4/bqad035/7056674
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    Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR
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    sciencedirect.com/science/article/pii/S2211124722008944
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    Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma
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    sciencedirect.com/science/article/pii/S2451945622002422
  31. Apr 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals
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    sciencedirect.com/science/article/pii/S1550413123001304
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    Coronavirus Subverts ER-phagy by Hijacking FAM134B and ATL3 into p62 Condensates to Facilitate Viral Replication
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    sciencedirect.com/science/article/pii/S2211124723002978
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    VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
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    sciencedirect.com/science/article/pii/S2211124723002206
  35. Mar 2023
  36. journals.lww.com journals.lww.com
    TUG-891 inhibits neuronal endoplasmic reticulum stress and... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2023/10000/TUG_891_inhibits_neuronal_endoplasmic_reticulum.34.aspx
  37. 52.53.155.43 52.53.155.43
    Remodeling of the Ribosomal Quality Control and Protein Translation by a Viral Ubiquitin Deconjugase
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  38. Feb 2023
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    Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity
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    sciencedirect.com/science/article/pii/S2589004223002468
  40. www.mdpi.com www.mdpi.com
    Selenium Protects Mouse Hypothalamic Cells from Glucocorticoid-Induced Endoplasmic Reticulum Stress Vulnerability and Insulin Signaling Impairment
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      DOI: 10.3390/antiox12020526

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  41. Jan 2023
  42. journals.lww.com journals.lww.com
    Valproate reduces retinal ganglion cell apoptosis in rats... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2023/07000/Valproate_reduces_retinal_ganglion_cell_apoptosis.37.aspx
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    Oxygen-carrying sequential preservation mitigates liver grafts ischemia-reperfusion injury
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  44. Nov 2022
  45. www.mdpi.com www.mdpi.com
    Neuroprotective Effects of Neuropeptide Y on Human Neuroblastoma SH-SY5Y Cells in Glutamate Excitotoxicity and ER Stress Conditions
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      DOI: 10.3390/cells11223665

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  46. Sep 2022
  47. www.sciencedirect.com www.sciencedirect.com
    De novo sphingolipid biosynthesis necessitates detoxification in cancer cells
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    sciencedirect.com/science/article/pii/S2211124722012566
  48. www.tandfonline.com www.tandfonline.com
    Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis
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      DOI: 10.1080/15548627.2022.2100105

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    tandfonline.com/doi/abs/10.1080/15548627.2022.2100105
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    OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy
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    sciencedirect.com/science/article/pii/S1550413122003606
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRE1α overexpression in malignant cells limits tumor progression by inducing an anti-cancer immune response
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      DOI: 10.1080/2162402X.2022.2116844

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    ncbi.nlm.nih.gov/pmc/articles/PMC9423862/
  51. Jul 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2451945622002458
  53. link.springer.com link.springer.com
    Transmissible ER stress between macrophages and tumor cells configures tumor microenvironment
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      DOI: 10.1007/s00018-022-04413-z

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    link.springer.com/article/10.1007/s00018-022-04413-z
  54. academic.oup.com academic.oup.com
    Small molecule-mediated insulin hypersecretion induces transient ER stress response and loss of beta cell function
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      DOI: 10.1210/endocr/bqac081

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  55. Apr 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Calcineurin/NFATc2 and PI3K/AKT signaling maintains β-cell identity and function during metabolic and inflammatory stress
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  57. Mar 2022
  58. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury
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    Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy
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    PERK reprograms hematopoietic progenitor cells to direct tumor-promoting myelopoiesis in the spleen
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    The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
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  62. Feb 2022
  63. www.tandfonline.com www.tandfonline.com
    The endoplasmic reticulum stress-mediated unfolded protein response protects against infection of goat endometrial epithelial cells by Trueperella pyogenes via autophagy
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  64. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Autophagic and apoptotic cell death induced by the quinoline derivative 2-(6-methoxynaphthalen-2-yl)quinolin-4-amine in pancreatic cancer cells is via ER stress and inhibition of Akt/mTOR signaling pathway
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  65. Jan 2022
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular Investigation of the Unfolded Protein Response in Select Human Tauopathies
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  67. journals.plos.org journals.plos.org
    Albendazole reduces hepatic inflammation and endoplasmic reticulum-stress in a mouse model of chronic Echinococcus multilocularis infection
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    Self-developed NF-κB inhibitor 270 protects against LPS-induced acute kidney injury and lung injury through improving inflammation
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    AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia
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  71. Dec 2021
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    β-catenin links cell seeding density to global gene expression during mouse embryonic stem cell differentiation
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  73. Nov 2021
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    TXNIP links anticipatory unfolded protein response to estrogen reprogramming glucose metabolism in breast cancer cells
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  76. Oct 2021
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    Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers
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  79. Aug 2021
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    Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors
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  83. Jul 2021
  84. elifesciences.org elifesciences.org
    Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
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    Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells
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    Neuronal VCP loss of function recapitulates FTLD-TDP pathology
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    Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides
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  88. May 2021
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    Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells
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    Pridopidine reduces mutant huntingtin-induced endoplasmic reticulum stress by modulation of the Sigma-1 receptor
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    Presynaptic store-operated Ca2+ entry drives excitatory spontaneous neurotransmission and augments endoplasmic reticulum stress
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    Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling
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  93. Apr 2021
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism
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    Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans
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    Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output
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  97. Feb 2021
  98. elifesciences.org elifesciences.org
    Stem cell transplantation rescued a primary open-angle glaucoma mouse model
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  99. Dec 2020
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    A novel HDAC6 inhibitor improves myelination of Schwann cells in a model of Charcot‐Marie‐Tooth disease type 1A
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  102. Sep 2020
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    Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress
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    Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
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    Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex
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    Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer
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    GCAP neuronal calcium sensor proteins mediate photoreceptor cell death in the rd3 mouse model of LCA12 congenital blindness by involving endoplasmic reticulum stress
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      anti-CHOP

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    5-Azacitidine Induces NOXA to Prime AML Cells for Venetoclax-mediated Apoptosis.
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      DOI: 10.1158/1078-0432.CCR-19-1900

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  109. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  110. Jan 2020
  111. www.sciencedirect.com www.sciencedirect.com
    The N-Degron Pathway Mediates ER-phagy
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      DOI: 10.1016/j.molcel.2019.06.028

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  112. www.sciencedirect.com www.sciencedirect.com
    Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction
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      DOI: 10.1016/j.cmet.2019.08.021

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  113. www.frontiersin.org www.frontiersin.org
    Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade
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      DOI: 10.3389/fncel.2019.00399

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  114. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  115. www.sciencedirect.com www.sciencedirect.com
    Hepatic nitric oxide synthase 1 adaptor protein regulates glucose homeostasis and hepatic insulin sensitivity in obese mice depending on its PDZ binding domain
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      DOI: 10.1016/j.ebiom.2019.08.033

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  116. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Profile of the Unfolded Protein Response in Rat Cerebellar Cortical Development
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      DOI: 10.1002/cne.24718

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  117. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.celrep.2018.12.005

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    sciencedirect.com/science/article/pii/S2211124718319168
  118. www.sciencedirect.com www.sciencedirect.com
    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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      DOI: 10.1016/j.ccell.2019.01.006

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  119. www.sciencedirect.com www.sciencedirect.com
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  120. Nov 2018
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TFAP2 transcription factors are regulators of lipid droplet biogenesis
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  122. www.sciencedirect.com www.sciencedirect.com
    Epidithiodiketopiperazines Inhibit Protein Degradation by Targeting Proteasome Deubiquitinase Rpn11
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  123. www.sciencedirect.com www.sciencedirect.com
    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
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    sciencedirect.com/science/article/pii/S0092867418305865
  124. www.sciencedirect.com www.sciencedirect.com
    Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance
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    sciencedirect.com/science/article/pii/S1550413118301207
  125. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S1550413117306113
  126. link.springer.com link.springer.com
    Cannabinoid Receptor Type 1 Agonist ACEA Protects Neurons from Death and Attenuates Endoplasmic Reticulum Stress-Related Apoptotic Pathway Signaling
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      Curator: @patriciaelyse_

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    link.springer.com/article/10.1007/s12640-017-9839-1
  127. Nov 2017
  128. academic.oup.com academic.oup.com
    Angiotensin II Causes β-Cell Dysfunction Through an ER Stress-Induced Proinflammatory Response
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    academic.oup.com/endo/article/158/10/3162/4083504/Angiotensin-II-Causes-Cell-Dysfunction-Through-an