1,866 Matching Annotations
  1. May 2021
  2. www.sciencedirect.com www.sciencedirect.com
    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
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    1. scibot 18 May 2021
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      DOI: 10.1016/j.cell.2021.04.022

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    sciencedirect.com/science/article/pii/S009286742100502X
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    Systemic administration of monovalent follistatin-like 3-Fc-fusion protein increases muscle mass in mice
    1
    1. scibot 15 May 2021
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      DOI: 10.1016/j.isci.2021.102488

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    sciencedirect.com/science/article/pii/S2589004221004569
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    Gene-environment interactions mediate stress susceptibility and resilience through the CaMKIIβ/TARPγ-8/AMPAR pathway
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    1. scibot 14 May 2021
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      DOI: 10.1016/j.isci.2021.102504

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    sciencedirect.com/science/article/pii/S2589004221004727
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    Anacardium Occidentale L. Leaf Extracts Protect Against Glutamate/H2O2-Induced Oxidative Toxicity and Induce Neurite Outgrowth: The Involvement of SIRT1/Nrf2 Signaling Pathway and Teneurin 4 Transmembrane Protein
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    1. scibot 14 May 2021
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      DOI: 10.3389/fphar.2021.627738

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    ncbi.nlm.nih.gov/pmc/articles/PMC8114061/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction
    1
    1. scibot 13 May 2021
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      DOI: 10.7554/eLife.61974

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    ncbi.nlm.nih.gov/pmc/articles/PMC8102060/
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    RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes
    1
    1. scibot 12 May 2021
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      DOI: 10.1016/j.celrep.2021.109102

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    sciencedirect.com/science/article/pii/S2211124721004368
  8. journals.physiology.org journals.physiology.org
    Lipotoxicity dysregulates immunoproteasome in podocytes and kidneys of type 2 diabetes
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    1. scibot 11 May 2021
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      DOI: 10.1152/ajprenal.00509.2020

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    journals.physiology.org/doi/abs/10.1152/ajprenal.00509.2020
  9. academic.oup.com academic.oup.com
    Acetyl-CoA regulation, OXPHOS integrity and leptin level are different in females with different onsets of obesity
    1
    1. scibot 10 May 2021
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      DOI: 10.1210/endocr/bqaa142

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    academic.oup.com/endo/article/161/11/bqaa142/5893756
  10. journals.physiology.org journals.physiology.org
    The β1 integrin plays a key role in lymphatic endothelial cell invasion in an optimized 3D Collagen matrix model
    1
    1. scibot 10 May 2021
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      DOI: 10.1152/ajpcell.00299.2020

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    journals.physiology.org/doi/abs/10.1152/ajpcell.00299.2020
  11. academic.oup.com academic.oup.com
    Removal of epididymal visceral adipose tissue prevents obesity-induced multi-organ insulin resistance in male mice
    1
    1. scibot 10 May 2021
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      DOI: 10.1210/jendso/bvab024

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    academic.oup.com/jes/article/5/5/bvab024/6145120
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    Specific inhibition of oncogenic RAS using cell-permeable RAS-binding domains
    1
    1. scibot 10 May 2021
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      DOI: 10.1016/j.chembiol.2021.04.013

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    sciencedirect.com/science/article/pii/S2451945621002063
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    Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis
    1
    1. scibot 09 May 2021
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      DOI: 10.1084/jem.20200662

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    rupress.org/jem/article/218/3/e20200662/211733/Loss-of-tRNA-modifying-enzyme-Elp3-activates-a-p53
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    Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice
    1
    1. scibot 09 May 2021
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      DOI: 10.1053/j.gastro.2020.11.044

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    sciencedirect.com/science/article/pii/S001650852035513X
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    Hdac9 inhibits medial artery calcification through down-regulation of Osterix
    1
    1. scibot 09 May 2021
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      DOI: 10.1016/j.vph.2020.106775

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    sciencedirect.com/science/article/pii/S1537189120300392
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    Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes
    1
    1. scibot 09 May 2021
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      DOI: 10.1016/j.stem.2020.12.016

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    sciencedirect.com/science/article/pii/S1934590920306007
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    MAP Kinase-Mediated Activation of RSK1 and MK2 Substrate Kinases
    1
    1. scibot 09 May 2021
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      DOI: 10.1016/j.str.2020.06.007

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    sciencedirect.com/science/article/pii/S0969212620302100
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    Thymoquinone administration ameliorates Alzheimer's disease-like phenotype by promoting cell survival in the hippocampus of amyloid beta1-42 infused rat model
    1
    1. scibot 09 May 2021
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      DOI: 10.1016/j.phymed.2020.153324

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    sciencedirect.com/science/article/pii/S0944711320301562
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    Diazepam and SL-327 synergistically attenuate anxiety-like behaviours in mice – Possible hippocampal MAPKs specificity
    1
    1. scibot 08 May 2021
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      DOI: 10.1016/j.neuropharm.2020.108302

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    sciencedirect.com/science/article/pii/S0028390820303701
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    DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells
    1
    1. scibot 08 May 2021
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      DOI: 10.1016/j.molcel.2021.01.038

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    sciencedirect.com/science/article/pii/S1097276521000587
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    TopBP1 assembles nuclear condensates to switch on ATR signaling
    1
    1. scibot 08 May 2021
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      DOI: 10.1016/j.molcel.2020.12.049

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    sciencedirect.com/science/article/pii/S1097276520309916
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    PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells
    1
    1. scibot 07 May 2021
      RRID:AB_2099233

      DOI: 10.1016/j.molcel.2020.08.018

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    sciencedirect.com/science/article/pii/S1097276520305815
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    ERK2 Phosphorylates PFAS to Mediate Posttranslational Control of De Novo Purine Synthesis
    1
    1. scibot 07 May 2021
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      DOI: 10.1016/j.molcel.2020.05.001

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    sciencedirect.com/science/article/pii/S1097276520303026
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    Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling
    1
    1. scibot 07 May 2021
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      DOI: 10.1016/j.jconrel.2021.03.015

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    sciencedirect.com/science/article/pii/S0168365921001267
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    Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy
    1
    1. scibot 07 May 2021
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      DOI: 10.1016/j.immuni.2020.09.006

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    sciencedirect.com/science/article/pii/S1074761320304003
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    m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development
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    1. scibot 06 May 2021
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      DOI: 10.1016/j.immuni.2020.05.003

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    sciencedirect.com/science/article/pii/S1074761320301849
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    In-gel proteasome assay to determine the activity, amount, and composition of proteasome complexes from mammalian cells or tissues
    1
    1. scibot 06 May 2021
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      DOI: 10.1016/j.xpro.2021.100526

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    sciencedirect.com/science/article/pii/S2666166721002331
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    Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains
    1
    1. scibot 06 May 2021
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      DOI: 10.1016/j.molcel.2021.04.012

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    sciencedirect.com/science/article/pii/S1097276521003178
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    Programmable Extracellular Vesicles for Macromolecule Delivery and Genome Modifications
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    1. scibot 05 May 2021
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      DOI: 10.1016/j.devcel.2020.11.007

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    sciencedirect.com/science/article/pii/S1534580720308832
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    Comparative Super-Resolution Mapping of Basal Feet Reveals a Modular but Distinct Architecture in Primary and Motile Cilia
    1
    1. scibot 05 May 2021
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      DOI: 10.1016/j.devcel.2020.09.015

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    sciencedirect.com/science/article/pii/S1534580720307176
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    The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction
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    1. scibot 05 May 2021
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      DOI: 10.1016/j.devcel.2020.08.006

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    sciencedirect.com/science/article/pii/S1534580720306304
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    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
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    1. scibot 05 May 2021
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      DOI: 10.1016/j.celrep.2021.109076

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    sciencedirect.com/science/article/pii/S2211124721004071
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    Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment
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      DOI: 10.1016/j.celrep.2021.109088

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    sciencedirect.com/science/article/pii/S2211124721004216
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    Feedforward Regulation of Glucose Metabolism by Steroid Hormones Drives a Developmental Transition in Drosophila
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      DOI: 10.1016/j.cub.2020.06.043

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    sciencedirect.com/science/article/pii/S0960982220308599
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    Proteasome stress in skeletal muscle mounts a long-range protective response that delays retinal and brain aging
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      DOI: 10.1016/j.cmet.2021.03.005

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    sciencedirect.com/science/article/pii/S1550413121001121
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    Excessive exercise training causes mitochondrial functional impairment and decreases glucose tolerance in healthy volunteers
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      DOI: 10.1016/j.cmet.2021.02.017

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    sciencedirect.com/science/article/pii/S1550413121001029
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    CRISPR screens in physiologic medium reveal conditionally essential genes in human cells
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      DOI: 10.1016/j.cmet.2021.02.005

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    sciencedirect.com/science/article/pii/S1550413121000619
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    Discovery of a covalent inhibitor of heat shock protein 90 with antitumor activity that blocks the co-chaperone binding via C-terminal modification
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      DOI: 10.1016/j.chembiol.2021.03.016

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    sciencedirect.com/science/article/pii/S2451945621001550
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    LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome
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      DOI: 10.1016/j.cell.2021.04.001

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    cell.com/cell/fulltext/S0092-8674(21)00436-0
  40. Apr 2021
  41. www.sciencedirect.com www.sciencedirect.com
    Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism
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    1. scibot 30 Apr 2021
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      DOI: 10.1016/j.cmet.2020.11.017

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    sciencedirect.com/science/article/pii/S1550413120306525
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    The Nuclear Receptor ESRRA Protects from Kidney Disease by Coupling Metabolism and Differentiation
    1
    1. scibot 30 Apr 2021
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      DOI: 10.1016/j.cmet.2020.11.011

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    High‐risk endometrial cancer proteomic profiling reveals that FBXW7 mutation alters L1CAM and TGM2 protein levels
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    Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3
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    Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer
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    Deletion of Fructokinase in the Liver or in the Intestine Reveals Differential Effects on Sugar-Induced Metabolic Dysfunction
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    Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma
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    Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum
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    LncRNA CALB2 sponges miR-30b-3p to promote odontoblast differentiation of human dental pulp stem cells via up-regulating RUNX2
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    iPSC modeling of stage-specific leukemogenesis reveals BAALC as a key oncogene in severe congenital neutropenia
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    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
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    Co-condensation between transcription factor and coactivator p300 modulates transcriptional bursting kinetics
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    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
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    Pharmacological inhibition of DEAD-Box RNA Helicase 3 attenuates stress granule assembly
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      HRP-conjugated anti-rabbit IgG

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    Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases
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    Oligophrenin-1 moderates behavioral responses to stress by regulating parvalbumin interneuron activity in the medial prefrontal cortex
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    Proteomic profile of urinary extracellular vesicles identifies AGP1 as a potential biomarker of primary aldosteronism
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    The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals
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    Embryonic Stem-Cell-Derived Extracellular Vesicles Maintain ESC Stemness by Activating FAK
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    Extracellular signal‐regulated kinases 2 (Erk2) and Erk5 in the central nervous system differentially contribute to central sensitization in male mice
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    DHCR24 Knockdown Lead to Hyperphosphorylation of Tau at Thr181, Thr231, Ser262, Ser396, and Ser422 Sites by Membrane Lipid-Raft Dependent PP2A Signaling in SH-SY5Y Cells
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    An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence
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    Functionally distinct roles for TET-oxidized 5-methylcytosine bases in somatic reprogramming to pluripotency
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    Re-evaluation of the effect of iodine on thyroid cell survival and function using PCCL3 and Nthy-ori 3-1 cells
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    MiR-3121-3p promotes tumor invasion and metastasis by suppressing Rap1GAP in papillary thyroid cancer in vitro
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  167. Jan 2021
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    Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins
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    FGF21 Induced by the ASK1-p38 Pathway Promotes Mechanical Cell Competition by Attracting Cells
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    Andrographolide suppresses NLRP3 inflammasome activation in microglia through induction of Parkin-mediated Mitophagy in in-vitro and in-vivo models of Parkinson disease
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    A novel HDAC6 inhibitor improves myelination of Schwann cells in a model of Charcot‐Marie‐Tooth disease type 1A
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    Vagal afferent fibers contribute to the anti-inflammatory reactions by vagus nerve stimulation in concanavalin A model of hepatitis in rats
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    Intranasal deferoxamine can improve memory in healthy C57 mice, suggesting a partially non‐disease‐specific pathway of functional neurologic improvement
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    CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion
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    Modulation of calcium signaling depends on the oligosaccharide of GM1 in Neuro2a mouse neuroblastoma cells
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  196. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
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    Two MicroRNAs Are Sufficient for Embryonic Patterning in C. elegans
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    Generating an MEIS1 homozygous knockout human embryonic stem cell line using the CRISPR/Cas9 system
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  200. Oct 2020
  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PKM2 Determines Myofiber Hypertrophy In Vitro and Increases in Response to Resistance Exercise in Human Skeletal Muscle
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    Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells
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    Heme Oxygenase-1 Induction by Blood-Feeding Arthropods Controls Skin Inflammation and Promotes Disease Tolerance
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      RRID:AB_2099233

      DOI: 10.1016/j.celrep.2020.108317

      Resource: (Cell Signaling Technology Cat# 7074, RRID:AB_2099233)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2099233

      What is this?
      RRIDCUR:Validated RRID:AB_2099233
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    sciencedirect.com/science/article/pii/S2211124720313061