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  1. Last 7 days
  2. www.cell.com www.cell.com
    Formate promotes invasion and metastasis in reliance on lipid metabolism
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    1. scibot 23 Nov 2024
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    cell.com/cell-reports/abstract/S2211-1247(23)01045-8
  3. Nov 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High fat diet induced hepatic insulin resistance per se attenuates murine de novo lipogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11550620/
  5. www.sciencedirect.com www.sciencedirect.com
    Cancer-associated fibroblasts maintain critical pancreatic cancer cell lipid homeostasis in the tumor microenvironment
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    1. scibot 14 Nov 2024
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    sciencedirect.com/science/article/pii/S2211124724013238
  6. Sep 2024
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    Myeloid beta-arrestin 2 depletion attenuates metabolic dysfunction-associated steatohepatitis via the metabolic reprogramming of macrophages
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    1. scibot 26 Sep 2024
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    sciencedirect.com/science/article/pii/S1550413124003620
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    Ceramide synthesis inhibitors prevent lipid-induced insulin resistance through the DAG-PKCε-insulin receptorT1150 phosphorylation pathway
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    1. scibot 25 Sep 2024
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    sciencedirect.com/science/article/pii/S2211124724010970
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    Intravenous lipid emulsions designed to meet preterm infant requirements increase plasma and tissue levels of docosahexaenoic acid and arachidonic acid in mice
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    1. scibot 13 Sep 2024
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    sciencedirect.com/science/article/pii/S0261561424002966
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    Combinatorial targeting of glutamine metabolism and lysosomal-based lipid metabolism effectively suppresses glioblastoma
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    1. scibot 05 Sep 2024
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    sciencedirect.com/science/article/pii/S2666379124004270
  11. Aug 2024
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    Immune suppression by human thymus-derived effector Tregs relies on glucose/lactate-fueled fatty acid synthesis
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    1. scibot 27 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724010325
  13. www.cell.com www.cell.com
    Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
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    1. scibot 21 Aug 2024
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    cell.com/cell-metabolism/fulltext/S1550-4131(24)00285-7
  14. May 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KLF4 promotes milk fat synthesis by regulating the PI3K-AKT-mTOR pathway and targeting FASN activation in bovine mammary epithelial cells
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    1. scibot 24 May 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11108978/
  16. Apr 2024
  17. www.nature.com www.nature.com
    Limitations in metabolic plasticity after traumatic injury are only moderately exacerbated by physical activity restriction
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    1. scibot 10 Apr 2024
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    nature.com/articles/s44324-024-00006-5
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation
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    1. scibot 03 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983109/
  19. Mar 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Semaglutide Improves Liver Steatosis and De Novo Lipogenesis Markers in Obese and Type-2-Diabetic Mice with Metabolic-Dysfunction-Associated Steatotic Liver Disease
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    1. scibot 17 Mar 2024
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      DOI: 10.3390/ijms25052961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10932050/
  21. Feb 2024
  22. aacrjournals.org aacrjournals.org
    FASN Gene Methylation is Associated with Fatty Acid Synthase Expression and Clinical-Genomic Features of Prostate Cancer
    2
    1. scibot 27 Feb 2024
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    aacrjournals.org/cancerrescommun/article/4/1/152/733383/FASN-Gene-Methylation-is-Associated-with-Fatty
  23. 52.53.155.43 52.53.155.43
    Exercise training adaptations in liver glycogen and glycerolipids require hepatic AMP-activated protein kinase in mice
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    1. scibot 22 Feb 2024
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  24. Jan 2024
  25. aacrjournals.org aacrjournals.org
    FASN Gene Methylation is Associated with Fatty Acid Synthase Expression and Clinical-Genomic Features of Prostate Cancer
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    1. scibot 20 Jan 2024
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    aacrjournals.org/cancerrescommun/article/4/1/152/733383/FASN-Gene-Methylation-is-Associated-with-Fatty
  26. Dec 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures
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    1. scibot 28 Dec 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10749327/
  28. Nov 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and gluconeogenesis in mice
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    1. scibot 04 Nov 2023
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    sciencedirect.com/science/article/pii/S2589004223022733
  30. Oct 2023
  31. www.cell.com www.cell.com
    Dominant-negative HNF1α mutant promotes liver steatosis and inflammation by regulating hepatic complement factor D
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    1. scibot 07 Oct 2023
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    cell.com/iscience/abstract/S2589-0042(23)02095-3
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SREBP-1 upregulates lipophagy to maintain cholesterol homeostasis in brain tumor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10528745/
  33. Aug 2023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Porcine reproductive and respiratory syndrome virus upregulates SMPDL3B to promote viral replication by modulating lipid metabolism
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    ncbi.nlm.nih.gov/pmc/articles/PMC10424083/
  35. 52.53.155.43 52.53.155.43
    PIIS2589004223017029-html.html
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    FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1
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    sciencedirect.com/science/article/abs/pii/S1097276523005609
  37. Jun 2023
  38. www.sciencedirect.com www.sciencedirect.com
    Modulation of cellular metabolism by protein crotonylation regulates pancreatic cancer progression
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    sciencedirect.com/science/article/pii/S2211124723006770
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    Peroxisome proliferator activated receptor-γ in osteoblasts controls bone formation and fat mass by regulating sclerostin expression
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    sciencedirect.com/science/article/pii/S2589004223010763
  40. 52.53.155.43 52.53.155.43
    Pregnancy-associated steroid effects on insulin sensitivity, adipogenesis and lipogenesis: Role of Wnt/β-catenin pathway
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      DOI: 10.1210/jendso/bvad076

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    52.53.155.43/0e2f928f1674babd136ee902d8de869217b4f809/bvad076 (1)-html.html
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    The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB
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    sciencedirect.com/science/article/pii/S2211124723005971
  42. May 2023
  43. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program
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    sciencedirect.com/science/article/pii/S2211124723004990
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    Metformin mitigates renal dysfunction in obese insulin-resistant rats via activation of the AMPK/PPARα pathway
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      DOI: 10.1007/s12272-023-01439-0

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    link.springer.com/article/10.1007/s12272-023-01439-0
  45. Apr 2023
  46. www.sciencedirect.com www.sciencedirect.com
    Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness
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    sciencedirect.com/science/article/pii/S1550413123001262
  47. Feb 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET
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    sciencedirect.com/science/article/pii/S2666379123000265
  49. Dec 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pleiotropic effects of Syntaxin16 identified by gene editing in cultured adipocytes
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      DOI: 10.3389/fcell.2022.1033501

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    ncbi.nlm.nih.gov/pmc/articles/PMC9716095/
  51. Oct 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes
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    sciencedirect.com/science/article/pii/S1550413122004120
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    Obesity caused by an OVOL2 mutation reveals dual roles of OVOL2 in promoting thermogenesis and limiting white adipogenesis
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    sciencedirect.com/science/article/pii/S1550413122004089
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    Cytoplasmic SIRT6-mediated ACSL5 deacetylation impedes nonalcoholic fatty liver disease by facilitating hepatic fatty acid oxidation
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    sciencedirect.com/science/article/pii/S1097276522009078
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency of peroxisomal NUDT7 stimulates de novo lipogenesis in hepatocytes
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      DOI: 10.1016/j.isci.2022.105135

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    ncbi.nlm.nih.gov/pmc/articles/PMC9523354/
  56. Aug 2022
  57. www.sciencedirect.com www.sciencedirect.com
    PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis
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    sciencedirect.com/science/article/pii/S1550413122003485
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    Cardiac ultrastructure inspired matrix induces advanced metabolic and functional maturation of differentiated human cardiomyocytes
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    sciencedirect.com/science/article/pii/S221112472200955X
  59. Jul 2022
  60. academic.oup.com academic.oup.com
    T cells mediate kidney tubular injury via impaired PDHA1 and Autophagy in type 1 diabetes
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  61. Jun 2022
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    Deficiency of C1QL1 reduced murine ovarian follicle reserve through intraovarian and endocrine control
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  63. May 2022
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    Tumor Microenvironment Acidity Triggers Lipid Accumulation in Liver Cancer via SCD1 Activation
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    Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy
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    Enhanced C/EBPβ function promotes hypertrophic versus hyperplastic fat tissue growth and prevents steatosis in response to high-fat diet feeding
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  67. Apr 2022
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    Meta-Inflammation and De Novo Lipogenesis Markers Are Involved in Metabolic Associated Fatty Liver Disease Progression in BTBR ob/ob Mice
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  69. Mar 2022
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    YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth
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  71. Feb 2022
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    Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor
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  73. Dec 2021
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    Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells
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  75. Sep 2021
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    Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation
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  77. Aug 2021
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    Excess dietary carbohydrate affects mitochondrial integrity as observed in brown adipose tissue
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  82. Jul 2021
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    In vivo isotope tracing reveals the versatility of glucose as a brown adipose tissue substrate
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    Gut Akkermansia muciniphila ameliorates metabolic dysfunction-associated fatty liver disease by regulating the metabolism of L-aspartate via gut-liver axis
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    SREBP-1c impairs ULK1 sulfhydration-mediated autophagic flux to promote hepatic steatosis in high-fat-diet-fed mice
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  89. May 2021
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    The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding
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    Contrasting recruitment of skin-associated adipose depots during cold challenge of mouse and human
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    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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  93. Apr 2021
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    An isocaloric moderately high-fat diet extends lifespan in male rats and Drosophila
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  95. Feb 2021
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    PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis
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  97. Jan 2021
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    Vasopressin mediates fructose-induced metabolic syndrome by activating the V1b receptor
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  100. Nov 2020
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    Gut Akkermansia muciniphila ameliorates non-alcoholic fatty liver disease by L-aspartate via interaction with liver
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  102. Oct 2020
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    The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development
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  104. Sep 2020
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    Discovery of Widespread Host Protein Interactions with the Pre-replicated Genome of CHIKV Using VIR-CLASP
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  106. Jan 2020
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    Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1
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    Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity
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    UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses
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    Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids
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  112. Nov 2018
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    Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC
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    ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P
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    Regulation of hepatic lipid accumulation and distribution by Agouti-related protein in male mice
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    Very Long Chain Fatty Acids Are Functionally Involved in Necroptosis
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    Maternal exercise modifies body composition and energy substrates handling in high‐fat/high‐sucrose diet fed male offspring
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    Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis
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      RRID:AB_2100796

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  119. www.sciencedirect.com www.sciencedirect.com
    Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling
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      RRID:AB_2100796

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    sciencedirect.com/science/article/pii/S0092867417312631
  120. Nov 2017
  121. onlinelibrary.wiley.com onlinelibrary.wiley.com
    TERT‐EZH2 network regulates lipid metabolism and DNA damage responses in glioblastoma
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      RRID:AB_2100796

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14152/full
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    A Cell-Autonomous Mammalian 12 hr Clock Coordinates Metabolic and Stress Rhythms
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      AB_2100796

      Curator: @chewbeccax

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  123. academic.oup.com academic.oup.com
    Liver NF-κB-Inducing Kinase Promotes Liver Steatosis and Glucose Counterregulation in Male Mice With Obesity
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      AB_2100796

      Curator: @bandrow

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    academic.oup.com/endo/article/158/5/1207/3098658/Liver-NF-B-Inducing-Kinase-Promotes-Liver