76 Matching Annotations
  1. May 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KLF4 promotes milk fat synthesis by regulating the PI3K-AKT-mTOR pathway and targeting FASN activation in bovine mammary epithelial cells
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    1. scibot 24 May 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11108978/
  3. Apr 2024
  4. www.nature.com www.nature.com
    Limitations in metabolic plasticity after traumatic injury are only moderately exacerbated by physical activity restriction
    1
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    nature.com/articles/s44324-024-00006-5
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983109/
  6. Mar 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Semaglutide Improves Liver Steatosis and De Novo Lipogenesis Markers in Obese and Type-2-Diabetic Mice with Metabolic-Dysfunction-Associated Steatotic Liver Disease
    1
    1. scibot 17 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10932050/
  8. Feb 2024
  9. aacrjournals.org aacrjournals.org
    FASN Gene Methylation is Associated with Fatty Acid Synthase Expression and Clinical-Genomic Features of Prostate Cancer
    2
    1. scibot 27 Feb 2024
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    aacrjournals.org/cancerrescommun/article/4/1/152/733383/FASN-Gene-Methylation-is-Associated-with-Fatty
  10. 52.53.155.43 52.53.155.43
    Exercise training adaptations in liver glycogen and glycerolipids require hepatic AMP-activated protein kinase in mice
    2
    1. scibot 22 Feb 2024
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      DOI: 10.1101/2023.09.01.555935

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  11. Jan 2024
  12. aacrjournals.org aacrjournals.org
    FASN Gene Methylation is Associated with Fatty Acid Synthase Expression and Clinical-Genomic Features of Prostate Cancer
    1
    1. scibot 20 Jan 2024
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    aacrjournals.org/cancerrescommun/article/4/1/152/733383/FASN-Gene-Methylation-is-Associated-with-Fatty
  13. Dec 2023
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures
    1
    1. scibot 28 Dec 2023
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      DOI: 10.3389/fnmol.2023.1323431

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    ncbi.nlm.nih.gov/pmc/articles/PMC10749327/
  15. Nov 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and gluconeogenesis in mice
    1
    1. scibot 04 Nov 2023
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      DOI: 10.1016/j.isci.2023.108196

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    sciencedirect.com/science/article/pii/S2589004223022733
  17. Oct 2023
  18. www.cell.com www.cell.com
    Dominant-negative HNF1α mutant promotes liver steatosis and inflammation by regulating hepatic complement factor D
    1
    1. scibot 07 Oct 2023
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    cell.com/iscience/abstract/S2589-0042(23)02095-3
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SREBP-1 upregulates lipophagy to maintain cholesterol homeostasis in brain tumor cells
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.112790

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    ncbi.nlm.nih.gov/pmc/articles/PMC10528745/
  20. Aug 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Porcine reproductive and respiratory syndrome virus upregulates SMPDL3B to promote viral replication by modulating lipid metabolism
    1
    1. scibot 19 Aug 2023
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  22. 52.53.155.43 52.53.155.43
    PIIS2589004223017029-html.html
    1
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.isci.2023.107625

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  23. www.sciencedirect.com www.sciencedirect.com
    FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1
    1
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.molcel.2023.07.017

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    sciencedirect.com/science/article/abs/pii/S1097276523005609
  24. Jun 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Modulation of cellular metabolism by protein crotonylation regulates pancreatic cancer progression
    1
    1. scibot 24 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112666

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    sciencedirect.com/science/article/pii/S2211124723006770
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    Peroxisome proliferator activated receptor-γ in osteoblasts controls bone formation and fat mass by regulating sclerostin expression
    1
    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.isci.2023.106999

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    sciencedirect.com/science/article/pii/S2589004223010763
  27. 52.53.155.43 52.53.155.43
    Pregnancy-associated steroid effects on insulin sensitivity, adipogenesis and lipogenesis: Role of Wnt/β-catenin pathway
    1
    1. scibot 15 Jun 2023
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      DOI: 10.1210/jendso/bvad076

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    52.53.155.43/0e2f928f1674babd136ee902d8de869217b4f809/bvad076 (1)-html.html
  28. www.sciencedirect.com www.sciencedirect.com
    The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112586

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    sciencedirect.com/science/article/pii/S2211124723005971
  29. May 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program
    1
    1. scibot 10 May 2023
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      DOI: 10.1016/j.celrep.2023.112488

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    sciencedirect.com/science/article/pii/S2211124723004990
  31. link.springer.com link.springer.com
    Metformin mitigates renal dysfunction in obese insulin-resistant rats via activation of the AMPK/PPARα pathway
    1
    1. scibot 04 May 2023
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      DOI: 10.1007/s12272-023-01439-0

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    link.springer.com/article/10.1007/s12272-023-01439-0
  32. Apr 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness
    1
    1. scibot 21 Apr 2023
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      DOI: 10.1016/j.cmet.2023.03.021

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    sciencedirect.com/science/article/pii/S1550413123001262
  34. Feb 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET
    1
    1. scibot 09 Feb 2023
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      DOI: 10.1016/j.xcrm.2023.100934

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    sciencedirect.com/science/article/pii/S2666379123000265
  36. Dec 2022
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pleiotropic effects of Syntaxin16 identified by gene editing in cultured adipocytes
    1
    1. scibot 08 Dec 2022
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      DOI: 10.3389/fcell.2022.1033501

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    ncbi.nlm.nih.gov/pmc/articles/PMC9716095/
  38. Oct 2022
  39. www.sciencedirect.com www.sciencedirect.com
    Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes
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    1. scibot 18 Oct 2022
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    sciencedirect.com/science/article/pii/S1550413122004120
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    Obesity caused by an OVOL2 mutation reveals dual roles of OVOL2 in promoting thermogenesis and limiting white adipogenesis
    1
    1. scibot 13 Oct 2022
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    sciencedirect.com/science/article/pii/S1550413122004089
  41. www.sciencedirect.com www.sciencedirect.com
    Cytoplasmic SIRT6-mediated ACSL5 deacetylation impedes nonalcoholic fatty liver disease by facilitating hepatic fatty acid oxidation
    1
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      DOI: 10.1016/j.molcel.2022.09.018

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    sciencedirect.com/science/article/pii/S1097276522009078
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency of peroxisomal NUDT7 stimulates de novo lipogenesis in hepatocytes
    1
    1. scibot 04 Oct 2022
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      DOI: 10.1016/j.isci.2022.105135

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    ncbi.nlm.nih.gov/pmc/articles/PMC9523354/
  43. Aug 2022
  44. www.sciencedirect.com www.sciencedirect.com
    PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis
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    1. scibot 30 Aug 2022
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    sciencedirect.com/science/article/pii/S1550413122003485
  45. www.sciencedirect.com www.sciencedirect.com
    Cardiac ultrastructure inspired matrix induces advanced metabolic and functional maturation of differentiated human cardiomyocytes
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      DOI: 10.1016/j.celrep.2022.111146

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    sciencedirect.com/science/article/pii/S221112472200955X
  46. Jul 2022
  47. academic.oup.com academic.oup.com
    T cells mediate kidney tubular injury via impaired PDHA1 and Autophagy in type 1 diabetes
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      DOI: 10.1210/clinem/dgac378

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac378/6613175
  48. Jun 2022
  49. academic.oup.com academic.oup.com
    Deficiency of C1QL1 reduced murine ovarian follicle reserve through intraovarian and endocrine control
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      DOI: 10.1210/endocr/bqac048

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    academic.oup.com/endo/article/163/6/bqac048/6569208
  50. May 2022
  51. aacrjournals.org aacrjournals.org
    Tumor Microenvironment Acidity Triggers Lipid Accumulation in Liver Cancer via SCD1 Activation
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      DOI: 10.1158/1541-7786.MCR-21-0699

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    aacrjournals.org/mcr/article/20/5/810/694642/Tumor-Microenvironment-Acidity-Triggers-Lipid
  52. www.sciencedirect.com www.sciencedirect.com
    Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy
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    sciencedirect.com/science/article/pii/S2211124722005630
  53. elifesciences.org elifesciences.org
    Enhanced C/EBPβ function promotes hypertrophic versus hyperplastic fat tissue growth and prevents steatosis in response to high-fat diet feeding
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      DOI: 10.7554/eLife.62625

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    elifesciences.org/articles/62625
  54. Apr 2022
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Meta-Inflammation and De Novo Lipogenesis Markers Are Involved in Metabolic Associated Fatty Liver Disease Progression in BTBR ob/ob Mice
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      DOI: 10.3390/ijms23073965

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    ncbi.nlm.nih.gov/pmc/articles/PMC8999923/
  56. Mar 2022
  57. www.sciencedirect.com www.sciencedirect.com
    YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth
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      DOI: 10.1016/j.devcel.2022.02.004

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    sciencedirect.com/science/article/pii/S1534580722000703
  58. Feb 2022
  59. www.sciencedirect.com www.sciencedirect.com
    Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor
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      DOI: 10.1016/j.ebiom.2022.103872

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    sciencedirect.com/science/article/pii/S2352396422000561
  60. Dec 2021
  61. reader.elsevier.com reader.elsevier.com
    Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells
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      DOI: 10.1016/j.celrep.2021.110063

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    reader.elsevier.com/reader/sd/pii/S2211124721015497
  62. Sep 2021
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    Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation
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  64. Aug 2021
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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
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  67. www.sciencedirect.com www.sciencedirect.com
    Excess dietary carbohydrate affects mitochondrial integrity as observed in brown adipose tissue
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    Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis
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  69. Jul 2021
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    In vivo isotope tracing reveals the versatility of glucose as a brown adipose tissue substrate
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    Fatty acid receptor GPR120 promotes breast cancer chemoresistance by upregulating ABC transporters expression and fatty acid synthesis
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gut Akkermansia muciniphila ameliorates metabolic dysfunction-associated fatty liver disease by regulating the metabolism of L-aspartate via gut-liver axis
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    SREBP-1c impairs ULK1 sulfhydration-mediated autophagic flux to promote hepatic steatosis in high-fat-diet-fed mice
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  76. May 2021
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    The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding
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  78. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
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    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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  80. Apr 2021
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    An isocaloric moderately high-fat diet extends lifespan in male rats and Drosophila
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  82. Feb 2021
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    PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis
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  84. Jan 2021
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    Vasopressin mediates fructose-induced metabolic syndrome by activating the V1b receptor
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  87. Nov 2020
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    Gut Akkermansia muciniphila ameliorates non-alcoholic fatty liver disease by L-aspartate via interaction with liver
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  89. Oct 2020
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    The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development
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  91. Sep 2020
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    Discovery of Widespread Host Protein Interactions with the Pre-replicated Genome of CHIKV Using VIR-CLASP
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  93. Jan 2020
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    Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1
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    Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity
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    UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses
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  97. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids
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  99. Nov 2018
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    Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC
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    ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P
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  102. academic.oup.com academic.oup.com
    Regulation of hepatic lipid accumulation and distribution by Agouti-related protein in male mice
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    Very Long Chain Fatty Acids Are Functionally Involved in Necroptosis
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    Maternal exercise modifies body composition and energy substrates handling in high‐fat/high‐sucrose diet fed male offspring
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    Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis
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    Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling
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  107. Nov 2017
  108. onlinelibrary.wiley.com onlinelibrary.wiley.com
    TERT‐EZH2 network regulates lipid metabolism and DNA damage responses in glioblastoma
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    A Cell-Autonomous Mammalian 12 hr Clock Coordinates Metabolic and Stress Rhythms
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    Liver NF-κB-Inducing Kinase Promotes Liver Steatosis and Glucose Counterregulation in Male Mice With Obesity
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