Hypothesis

35 Matching Annotations

Last 7 days
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Histone Methyltransferase KMT2D is a Critical Mediator of Lineage Plasticity and Therapeutic Response in Castration Resistant Prostate Cancer

1
1. scibot 14 Feb 2026
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1158/0008-5472.CAN-25-2053
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12900249/
Aug 2025
www.biorxiv.org www.biorxiv.org

Estrogen Receptor Enhancers Sensitive to Low Doses of Hormone Specify Distinct Molecular and Biological Outcomes

1
1. scibot 20 Aug 2025
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1101/2025.08.08.669412
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

biorxiv.org/content/10.1101/2025.08.08.669412v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Androgen receptor–mediated assisted loading of the glucocorticoid receptor modulates transcriptional responses in prostate cancer cells

1
1. scibot 05 Aug 2025
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1101/gr.280224.124
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12315708/
Feb 2025
www.cell.com www.cell.com

CRISPR screening identifies regulators of enhancer-mediated androgen receptor transcription in advanced prostate cancer

1
1. scibot 21 Feb 2025
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1016/j.celrep.2025.115312
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

cell.com/cell-reports/fulltext/S2211-1247(25)00083-X
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer

2
1. scibot 31 Jul 2024
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1158/2159-8290.CD-23-0539
  
  Resource: AB_2104842
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
2. scibot 31 Jul 2024
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1158/2159-8290.CD-23-0539
  
  Resource: AB_2104842
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
May 2024
www.sciencedirect.com www.sciencedirect.com

The evolutionarily ancient FOXA transcription factors shape the murine gut microbiome via control of epithelial glycosylation

1
1. scibot 31 May 2024
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1016/j.devcel.2024.05.006
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S153458072400323X
Apr 2024
link.springer.com link.springer.com

EP300/CREBBP acetyltransferase inhibition limits steroid receptor and FOXA1 signaling in prostate cancer cells

1
1. scibot 10 Apr 2024
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1007/s00018-024-05209-z
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

link.springer.com/article/10.1007/s00018-024-05209-z
Feb 2024
www.sciencedirect.com www.sciencedirect.com

FOXA1 forms biomolecular condensates that unpack condensed chromatin to function as a pioneer factor

1
1. scibot 09 Feb 2024
  
  in Public
  
  AB_2104842
  
  DOI: 10.1016/j.molcel.2023.11.020
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/abs/pii/S1097276523009656
Jul 2023
www.sciencedirect.com www.sciencedirect.com

High FOXA1 levels induce ER transcriptional reprogramming, a pro-metastatic secretome, and metastasis in endocrine-resistant breast cancer

1
1. scibot 21 Jul 2023
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1016/j.celrep.2023.112821
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472300832X
Nov 2022
www.sciencedirect.com www.sciencedirect.com

FOXA2 drives lineage plasticity and KIT pathway activation in neuroendocrine prostate cancer

1
1. scibot 04 Nov 2022
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1016/j.ccell.2022.10.011
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610822005025
Sep 2022
www.sciencedirect.com www.sciencedirect.com

FOXA1 regulates alternative splicing in prostate cancer

1
1. scibot 29 Sep 2022
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1016/j.celrep.2022.111404
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722012414
Jul 2022
www.sciencedirect.com www.sciencedirect.com

FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma

1
1. scibot 15 Jul 2022
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1016/j.devcel.2022.06.017
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580722004580
Apr 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cistrome and transcriptome analysis identifies unique androgen receptor (AR) and AR-V7 splice variant chromatin binding and transcriptional activities

1
1. scibot 05 Apr 2022
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1038/s41598-022-09371-x
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8969163/
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity

1
1. scibot 08 Sep 2021
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1016/j.celrep.2021.109625
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721010639
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 12 Aug 2021
  
  in Public
  
  AB_2104842
  
  DOI: 10.1016/j.celrep.2019.02.036
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6408623/
www.sciencedirect.com www.sciencedirect.com

ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer

1
1. scibot 06 Aug 2021
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1016/j.ccell.2019.01.008
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S153561081930042X
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 29 Jul 2021
  
  in Public
  
  AB_2104842
  
  DOI: 10.1210/en.2017-00361
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5695839/
www.sciencedirect.com www.sciencedirect.com

The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer

2
1. scibot 27 Jul 2021
  
  in Public
  
  RRID:AB_04842
  
  DOI: 10.1016/j.celrep.2019.09.032
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842 RRIDCUR:Unresolved RRIDCUR:Incorrect
2. scibot 27 Jul 2021
  
  in Public
  
  RRID:AB_04842
  
  DOI: 10.1016/j.celrep.2019.09.032
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842 RRIDCUR:Unresolved RRIDCUR:Incorrect
Visit annotations in context

Tags

RRIDCUR:Incorrect

RRID:AB_2104842

RRIDCUR:Unresolved

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719312203
Apr 2021
www.sciencedirect.com www.sciencedirect.com

FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer

1
1. scibot 22 Apr 2021
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1016/j.ccell.2020.08.003
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2104842
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610820304141
www.cell.com www.cell.com

IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis

1
1. scibot 20 Apr 2021
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1016/j.ccell.2020.06.007
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2104842
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2104842

Annotators

scibot

URL

cell.com/cancer-cell/fulltext/S1535-6108(20)30311-1
Feb 2021
www.nature.com www.nature.com

Androgen receptor and its splice variant, AR-V7, differentially induce mRNA splicing in prostate cancer cells

1
1. scibot 28 Feb 2021
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1038/s41598-021-81164-0
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

nature.com/articles/s41598-021-81164-0
Jan 2021
www.sciencedirect.com www.sciencedirect.com

Post-transcriptional Gene Regulation by MicroRNA-194 Promotes Neuroendocrine Transdifferentiation in Prostate Cancer

1
1. scibot 07 Jan 2021
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1016/j.celrep.2020.108585
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2104842
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720315746
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Cistrome Partitioning Reveals Convergence of Somatic Mutations and Risk Variants on Master Transcription Regulators in Primary Prostate Tumors

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1016/j.ccell.2019.10.005
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610819304799
elifesciences.org elifesciences.org

Mutationally-activated PI3’-kinase-α promotes de-differentiation of lung tumors initiated by the BRAFV600E oncoprotein kinase

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.7554/eLife.43668
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2104842

Annotators

scibot

URL

elifesciences.org/articles/43668
www.sciencedirect.com www.sciencedirect.com

Pioneer Factor-Nucleosome Binding Events during Differentiation Are Motif Encoded

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1016/j.molcel.2019.05.025
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276519303971
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  AB_2104842
  
  DOI: 10.1016/j.celrep.2019.02.036
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @ethanbadger
  
  SciCrunch record: AB_2104842
  
  What is this?
  
  RRID:AB_2104842 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719302074
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:AB_2104842
  
  DOI: 10.1016/j.molcel.2019.02.024
  
  Resource: (Abcam Cat# ab23738, RRID:AB_2104842)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2104842
  
  What is this?
  
  RRID:AB_2104842 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276519301352
Nov 2018
www.sciencedirect.com www.sciencedirect.com

ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2104842
  
  Curator: @Jmenke
  
  Resource used:
  
  (Abcam Cat# ab23738, RRID:AB_2104842)
  
  SciCrunch record: RRID:AB_2104842
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2104842 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276518306890
www.sciencedirect.com www.sciencedirect.com

A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2104842
  
  Resource used:
  
  (Abcam Cat# ab23738, RRID:AB_2104842)
  
  SciCrunch record: RRID:AB_2104842
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867418306494
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2104842
  
  Curator: @evieth
  
  Resource used:
  
  (Abcam Cat# ab23738, RRID:AB_2104842)
  
  SciCrunch record: RRID:AB_2104842
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2104842 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2104842

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5967868/
elifesciences.org elifesciences.org

BRG1 governs glucocorticoid receptor interactions with chromatin and pioneer factors across the genome

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2104842
  
  Curator: @evieth
  
  Resource used:
  
  (Abcam Cat# ab23738, RRID:AB_2104842)
  
  SciCrunch record: RRID:AB_2104842
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2104842 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2104842

Annotators

scibot

URL

elifesciences.org/articles/35073
academic.oup.com academic.oup.com

Pioneer Factors FOXA1 and FOXA2 Assist Selective Glucocorticoid Receptor Signaling in Human Endometrial Cells

1
1. scibot 05 Nov 2018
  
  in Public
  
  AB_2104842
  
  Resource used:
  
  (Abcam Cat# ab23738, RRID:AB_2104842)
  
  SciCrunch record: RRID:AB_2104842
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2104842
Visit annotations in context

Tags

RRID:AB_2104842

Annotators

scibot

URL

academic.oup.com/endo/article/158/11/4076/4096797
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:AB_2104842
  
  Curator: @chewbeccax
  
  Resource used:
  
  (Abcam Cat# ab23738, RRID:AB_2104842)
  
  SciCrunch record: RRID:AB_2104842
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2104842 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2104842

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867417308140