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Development of a cyst-targeted therapy for polycystic kidney disease using an antagonistic dimeric IgA monoclonal antibody against cMET

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  DOI: 10.1016/j.xcrm.2025.102335
  
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sciencedirect.com/science/article/pii/S2666379125004082
Aug 2025
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Differential Efficacy of Bevacizumab and Erlotinib in Preclinical Models of Renal Medullary Carcinoma and Fumarate Hydratase–Deficient Renal Cell Carcinoma

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pmc.ncbi.nlm.nih.gov/articles/PMC12323885/
Jul 2025
52.53.155.43 52.53.155.43

NE-activated β2-AR/β-arrestin 2/Src pathway mediates duodenal hyperpermeability induced by water-immersion restraint stress

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1. scibot 19 Jul 2025
  
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  DOI: 10.1152/ajpcell.00412.2022
  
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52.53.155.43/aa11c879e9e1e4947e7d807b75499a792887d07f/yan-et-al-2023-ne-activated-2-ar--arrestin-2-src-pathway-mediates-duodenal-hyperpermeability-induced-by-water-html.html
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TBK1 phagosomal recruitment enhances antifungal immunity via positive feedback regulation with SRC

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.115972
  
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cell.com/cell-reports/abstract/S2211-1247(25)00743-0
Jun 2025
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BPS Publications

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1. scibot 22 Jun 2025
  
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  DOI: 10.1111/bph.70112
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70112
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Dynamic decoding of VEGF signaling and coordinated control of multiple phenotypes by the Src-TEM4-YAP pathway

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  DOI: 10.1016/j.cels.2025.101321
  
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sciencedirect.com/science/article/pii/S2405471225001541
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Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy

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1. scibot 03 Jun 2025
  
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sciencedirect.com/science/article/pii/S1074761325002274
May 2025
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1-s2.0-S258900422500879X-main-html.html

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1. scibot 18 May 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12152665/
Apr 2025
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Fatty acid uptake activates an AXL–CAV1–β-catenin axis to drive melanoma progression

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pmc.ncbi.nlm.nih.gov/articles/PMC11960706/
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Signaling and transcriptional dynamics underlying early adaptation to oncogenic BRAF inhibition

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1. scibot 01 Apr 2025
  
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  DOI: 10.1016/j.cels.2025.101239
  
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sciencedirect.com/science/article/pii/S2405471225000729
Mar 2025
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IL-17RA signaling provides dual tumor-suppressor function during late-stage colorectal carcinogenesis

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1. scibot 05 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.005
  
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cell.com/immunity/fulltext/S1074-7613(25)00073-1
Jan 2025
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Anandamide Inhibits Vascular Smooth Muscle Migration, Endothelial Adhesion Protein Expression and Monocyte Adhesion of Human Coronary Artery Cells

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1. scibot 24 Jan 2025
  
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  DOI: 10.3390/cells13242108
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11727187/
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Target protein identification in live cells and organisms with a non-diffusive proximity tagging system

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1. scibot 04 Jan 2025
  
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  DOI: 10.7554/eLife.102667
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11677243/
Aug 2024
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Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer

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1. scibot 22 Aug 2024
  
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  DOI: 10.1186/s13046-024-03124-6
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11321020/
Jul 2024
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PAI-1 uncouples integrin-β1 from restrain by membrane-bound β-catenin to promote collagen fibril remodeling in obesity-related neoplasms

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1. scibot 25 Jul 2024
  
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sciencedirect.com/science/article/pii/S2211124724008568
Jun 2024
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RAPSYN-mediated neddylation of BCR-ABL alternatively determines the fate of Philadelphia chromosome-positive leukemia

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1. scibot 14 Jun 2024
  
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  DOI: 10.7554/eLife.88375
  
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elifesciences.org/articles/88375
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Anti-tumor effects of tirbanibulin in squamous cell carcinoma cells are mediated via disruption of tubulin-polymerization

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1. scibot 13 Jun 2024
  
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  DOI: 10.1007/s00403-024-03032-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11161541/
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FAK regulates tension transmission to the nucleus and endothelial transcriptome independent of kinase activity

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1. scibot 04 Jun 2024
  
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  DOI: 10.1016/j.celrep.2024.114297
  
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sciencedirect.com/science/article/pii/S2211124724006259
May 2024
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Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation

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1. scibot 04 May 2024
  
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  DOI: 10.1101/2024.01.21.576568
  
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52.53.155.43/5631ba0ece03be5b6bc39fba9c8a58e52d07c519/2024.01.21.576568v1.full-html.html
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Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas

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1. scibot 03 May 2024
  
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  DOI: 10.1016/j.ccell.2024.04.007
  
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sciencedirect.com/science/article/pii/S1535610824001314
Apr 2024
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Sarcoma cells secrete hypoxia-modified collagen VI to weaken the lung endothelial barrier and promote metastasis

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1. scibot 19 Apr 2024
  
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  DOI: 10.1158/0008-5472.CAN-23-0910
  
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aacrjournals.org/cancerres/article/84/7/977/742043/Sarcoma-Cells-Secrete-Hypoxia-Modified-Collagen-VI
Sep 2023
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Profiling of drug resistance in Src kinase at scale uncovers a regulatory network coupling autoinhibition and catalytic domain dynamics

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1. scibot 08 Sep 2023
  
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  DOI: 10.1016/j.chembiol.2023.08.005
  
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sciencedirect.com/science/article/abs/pii/S2451945623002775
Jul 2023
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A back-door insight into the modulation of Src kinase activity by the polyamine spermidine

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1. scibot 12 Jul 2023
  
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  DOI: 10.7554/eLife.85872
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10328509/
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FUNDC1: a key mediator of adenosine A2BR activation-induced inhibition of cardiac mitophagy under ischemia/reperfusion conditions

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1. scibot 06 Jul 2023
  
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  DOI: 10.21037/cdt-22-468
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10315432/
Jun 2023
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The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity

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1. scibot 28 Jun 2023
  
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  DOI: 10.1016/j.immuni.2023.06.002
  
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sciencedirect.com/science/article/pii/S1074761323002376
May 2023
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PhosY-secretome profiling combined with kinase-substrate interaction screening defines active c-Src-driven extracellular signaling

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1. scibot 27 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112539
  
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sciencedirect.com/science/article/pii/S2211124723005508
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KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells

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  DOI: 10.1016/j.celrep.2022.111077
  
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sciencedirect.com/science/article/pii/S2211124722008750
Apr 2023
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Nuclear translocation of cGAS orchestrates VEGF-A-mediated angiogenesis

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  DOI: 10.1016/j.celrep.2023.112328
  
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sciencedirect.com/science/article/pii/S221112472300339X
Jan 2023
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BPS Publications

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1. scibot 14 Jan 2023
  
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  DOI: 10.1111/bph.16007
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16007
Nov 2022
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RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation

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1. scibot 10 Nov 2022
  
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  DOI: 10.1016/j.isci.2022.105184
  
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sciencedirect.com/science/article/pii/S2589004222014560
Sep 2022
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Targeting of c-MET and AXL by cabozantinib is a potential therapeutic strategy for patients with head and neck cell carcinoma

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  DOI: 10.1016/j.xcrm.2022.100659
  
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sciencedirect.com/science/article/pii/S2666379122001914
Aug 2022
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β-Glucocerebrosidase Deficiency Activates an Aberrant Lysosome-Plasma Membrane Axis Responsible for the Onset of Neurodegeneration

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1. scibot 16 Aug 2022
  
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  DOI: 10.3390/cells11152343
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9367513/
May 2022
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Translational Strategies for Repotrectinib in Neuroblastoma

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1. scibot 05 May 2022
  
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  DOI: 10.1158/1535-7163.MCT-21-0126
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8571000/
Jan 2022
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Inhibition of transcription factor NFAT activity in activated platelets enhances their aggregation and exacerbates gram-negative bacterial septicemia

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1. scibot 07 Jan 2022
  
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  DOI: 10.1016/j.immuni.2021.12.002
  
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sciencedirect.com/science/article/pii/S1074761321005355
Nov 2021
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Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling

1
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  RRID:AB_2106059
  
  DOI: 10.1016/j.celrep.2021.110036
  
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Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis

1
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  RRID:AB_2106059
  
  DOI: 10.1016/j.celrep.2021.110056
  
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Dissecting VEGF-induced acute versus chronic vascular hyperpermeability: Essential roles of dimethylarginine dimethylaminohydrolase-1

1
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  RRID:AB_2106059
  
  DOI: 10.1016/j.isci.2021.103189
  
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Tumor necrosis factor ligand-related molecule 1A maintains blood–retinal barrier via modulating SHP-1-Src-VE-cadherin signaling in diabetic retinopathy

1
1. scibot 26 Oct 2021
  
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  RRID:AB_2106059
  
  DOI: 10.1096/fj.202100807RR
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202100807RR
Sep 2021
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Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity

1
1. scibot 30 Sep 2021
  
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  RRID:AB_2106059
  
  DOI: 10.1016/j.cmet.2021.09.003
  
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Senescent immune cells release grancalcin to promote skeletal aging

1
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  DOI: 10.1016/j.cmet.2021.08.009
  
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Aug 2021
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Hypoxic Preconditioning Maintains GLT-1 Against Transient Global Cerebral Ischemia Through Upregulating Cx43 and Inhibiting c-Src

1
1. scibot 08 Aug 2021
  
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  RRID:AB_2106059
  
  DOI: 10.3389/fnmol.2018.00344
  
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AhR ligand aminoflavone suppresses α6‐integrin–Src–Akt signaling to attenuate tamoxifen resistance in breast cancer cells

1
1. scibot 03 Aug 2021
  
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  RRID:AB_2106059
  
  DOI: 10.1002/jcp.27013
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6202151/
May 2021
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Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases

1
1. scibot 07 May 2021
  
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  RRID:AB_2106059
  
  DOI: 10.1016/j.molcel.2020.06.018
  
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Apr 2021
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NOX1/NADPH oxidase promotes synaptic facilitation induced by repeated D2 receptor stimulation; involvement in behavioral repetition

1
1. scibot 08 Apr 2021
  
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  rabbit anti-Src family
  
  DOI: 10.1523/JNEUROSCI.2121-20.2021
  
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jneurosci.org/content/41/12/2780
Nov 2020
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TSPAN1: A Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance

1
1. scibot 11 Nov 2020
  
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  Src
  
  DOI: 10.3390/cancers12113269
  
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Oct 2020
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Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex

1
1. scibot 16 Oct 2020
  
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  RRID:AB_2106059
  
  DOI: 10.1016/j.devcel.2020.05.031
  
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cell.com/developmental-cell/abstract/S1534-5807(20)30420-2
Sep 2020
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Extracellular Vesicles Isolated from Human Induced Pluripotent Stem Cell-Derived Neurons Contain a Transcriptional Network

1
1. scibot 17 Sep 2020
  
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  AB_2106059
  
  DOI: 10.1007/s11064-020-03019-w
  
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Loratadine, an antihistamine drug, exhibits anti-inflammatory activity through suppression of the NF-kB pathway

1
1. scibot 09 Sep 2020
  
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  RRID:AB_2106059
  
  DOI: 10.1016/j.bcp.2020.113949
  
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Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation

1
1. scibot 03 Sep 2020
  
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  RRID:AB_2106059
  
  DOI: 10.1016/j.celrep.2019.12.075
  
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sciencedirect.com/science/article/pii/S2211124719317401
Aug 2020
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Rare osteosarcoma cell subpopulation protein array and profiling using imaging mass cytometry and bioinformatics analysis

1
1. scibot 27 Aug 2020
  
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  Src
  
  DOI: 10.1186/s12885-020-07203-7
  
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link.springer.com/article/10.1186/s12885-020-07203-7
Jan 2020
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Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2106059
  
  DOI: 10.1016/j.ccell.2019.08.006
  
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sciencedirect.com/science/article/pii/S1535610819303745
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HIV-1 Envelope Overcomes NLRP3-Mediated Inhibition of F-Actin Polymerization for Viral Entry

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2106059
  
  DOI: 10.1016/j.celrep.2019.02.095
  
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Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma

1
1. scibot 13 Jan 2020
  
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  AB_2106059
  
  DOI: 10.1016/j.ccell.2019.05.003
  
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Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn‐independent effect of tau on calcium

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2106059
  
  DOI: 10.1002/jnr.24517
  
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onlinelibrary.wiley.com/doi/abs/10.1002/jnr.24517
onlinelibrary.wiley.com onlinelibrary.wiley.com

Astrocyte truncated tropomyosin receptor kinase B mediates brain‐derived neurotrophic factor anti‐apoptotic effect leading to neuroprotection

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2106059
  
  DOI: 10.1111/jnc.14476
  
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onlinelibrary.wiley.com/doi/full/10.1111/jnc.14476
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KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2106059
  
  DOI: 10.1016/j.ccell.2018.10.001
  
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Small-Molecule Inhibition of the UNC-Src Interaction Impairs Dynamic Src Localization in Cells

1
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  RRID:AB_2106059
  
  DOI: 10.1016/j.chembiol.2019.02.019
  
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sciencedirect.com/science/article/pii/S2451945619300741
Nov 2018
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Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling

1
1. scibot 05 Nov 2018
  
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  AB_2106059
  
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AhR ligand aminoflavone suppresses α6‐integrin–Src–Akt signaling to attenuate tamoxifen resistance in breast cancer cells

1
1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6202151/
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Adaptive Fibrogenic Reprogramming of Osteosarcoma Stem Cells Promotes Metastatic Growth

1
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Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf)

2
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0960982217311715
Nov 2017
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YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis

1
1. scibot 08 Nov 2017
  
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  RRID:AB_2106059
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1534580717306305