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FLT3L-based drug conjugate effectively targets chemoresistant leukemia stem cells in acute myeloid leukemia

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1. scibot 23 Sep 2025
  
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  RRID:AB_2107051
  
  DOI: 10.1016/j.xcrm.2025.102365
  
  Resource: (Cell Signaling Technology Cat# 3464, RRID:AB_2107051)
  
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sciencedirect.com/science/article/pii/S2666379125004380
May 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice

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1. scibot 07 May 2024
  
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  RRID:AB_2107051
  
  DOI: 10.1016/j.cell.2024.04.009
  
  Resource: (Cell Signaling Technology Cat# 3464, RRID:AB_2107051)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11149630/
Apr 2024
52.53.155.43 52.53.155.43

Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1

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1. scibot 11 Apr 2024
  
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  RRID:AB_2107051
  
  DOI: 10.1016/j.isci.2024.109576
  
  Resource: (Cell Signaling Technology Cat# 3464, RRID:AB_2107051)
  
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52.53.155.43/43deb73e3f715bad3d2167b3c6b37658d9cd796b/1-s2.0-S2589004224007983-main-html.html
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib

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1. scibot 19 Mar 2024
  
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  RRID:AB_2107051
  
  DOI: 10.1158/0008-5472.CAN-23-1534
  
  Resource: (Cell Signaling Technology Cat# 3464, RRID:AB_2107051)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10940854/
Nov 2023
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A combinatorial therapeutic approach to enhance FLT3-ITD AML treatment

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1. scibot 28 Nov 2023
  
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  RRID:AB_2107051
  
  DOI: 10.1016/j.xcrm.2023.101286
  
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sciencedirect.com/science/article/pii/S2666379123004809
Feb 2022
www.nature.com www.nature.com

Activating JAK-mutations confer resistance to FLT3 kinase inhibitors in FLT3-ITD positive AML in vitro and in vivo

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1. scibot 01 Feb 2022
  
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  RRID:AB_2107051
  
  DOI: 10.1038/s41375-020-01077-1
  
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nature.com/articles/s41375-020-01077-1
Jun 2021
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The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance

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1. scibot 25 Jun 2021
  
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  AB_2107051
  
  DOI: 10.1016/j.ccell.2021.06.003
  
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sciencedirect.com/science/article/pii/S1535610821002865