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FLT3L-based drug conjugate effectively targets chemoresistant leukemia stem cells in acute myeloid leukemia

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1. scibot 23 Sep 2025
  
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  RRID:AB_2107052
  
  DOI: 10.1016/j.xcrm.2025.102365
  
  Resource: (Cell Signaling Technology Cat# 3462, RRID:AB_2107052)
  
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sciencedirect.com/science/article/pii/S2666379125004380
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling

1
1. scibot 17 Jul 2024
  
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  AB_2107052
  
  DOI: 10.1016/j.xcrm.2024.101645
  
  Resource: (Cell Signaling Technology Cat# 3462, RRID:AB_2107052)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11293342/
May 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice

1
1. scibot 07 May 2024
  
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  RRID:AB_2107052
  
  DOI: 10.1016/j.cell.2024.04.009
  
  Resource: (Cell Signaling Technology Cat# 3462, RRID:AB_2107052)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11149630/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib

1
1. scibot 19 Mar 2024
  
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  RRID:AB_2107052
  
  DOI: 10.1158/0008-5472.CAN-23-1534
  
  Resource: (Cell Signaling Technology Cat# 3462, RRID:AB_2107052)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10940854/
Nov 2023
www.sciencedirect.com www.sciencedirect.com

A combinatorial therapeutic approach to enhance FLT3-ITD AML treatment

1
1. scibot 28 Nov 2023
  
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  RRID:AB_2107052
  
  DOI: 10.1016/j.xcrm.2023.101286
  
  Resource: (Cell Signaling Technology Cat# 3462, RRID:AB_2107052)
  
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sciencedirect.com/science/article/pii/S2666379123004809
Jul 2023
52.53.155.43 52.53.155.43

cd-22-0411-html.html

1
1. scibot 01 Jul 2023
  
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  RRID:AB_2107052
  
  DOI: 10.1158/2159-8290.CD-22-0411
  
  Resource: (Cell Signaling Technology Cat# 3462, RRID:AB_2107052)
  
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52.53.155.43/453457acda6208aed297e8061921a5c2d2ddddf2/cd-22-0411-html.html
Jan 2023
www.nature.com www.nature.com

Pacritinib inhibits glucose consumption in squamous cell lung cancer cells by targeting FLT3

1
1. scibot 28 Jan 2023
  
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  RRID:AB_2107052
  
  DOI: 10.1038/s41598-023-28576-2
  
  Resource: (Cell Signaling Technology Cat# 3462, RRID:AB_2107052)
  
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nature.com/articles/s41598-023-28576-2
Dec 2022
www.sciencedirect.com www.sciencedirect.com

Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia

1
1. scibot 24 Dec 2022
  
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  RRID:AB_2107052
  
  DOI: 10.1016/j.ccell.2022.12.002
  
  Resource: (Cell Signaling Technology Cat# 3462, RRID:AB_2107052)
  
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  SciCrunch record: RRID:AB_2107052
  
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sciencedirect.com/science/article/pii/S1535610822005888
Jan 2022
onlinelibrary.wiley.com onlinelibrary.wiley.com

SKI-G-801, an AXL kinase inhibitor, blocks metastasis through inducing anti-tumor immune responses and potentiates anti-PD-1 therapy in mouse cancer models

1
1. scibot 05 Jan 2022
  
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  3462
  
  DOI: 10.1002/cti2.1364
  
  Resource: (Cell Signaling Technology Cat# 3462, RRID:AB_2107052)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2107052
  
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  RRID:AB_2107052 RRIDCUR:Missing
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onlinelibrary.wiley.com/doi/10.1002/cti2.1364
Jun 2021
www.sciencedirect.com www.sciencedirect.com

The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance

1
1. scibot 25 Jun 2021
  
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  RRID:AB_2107052
  
  DOI: 10.1016/j.ccell.2021.06.003
  
  Resource: (Cell Signaling Technology Cat# 3462, RRID:AB_2107052)
  
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  SciCrunch record: RRID:AB_2107052
  
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sciencedirect.com/science/article/pii/S1535610821002865
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia

1
1. scibot 22 Apr 2021
  
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  RRID:AB_2107052
  
  DOI: 10.1016/j.ccell.2020.10.010
  
  Resource: (Cell Signaling Technology Cat# 3462, RRID:AB_2107052)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2107052
  
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  RRIDCUR:Validated RRID:AB_2107052
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RRID:AB_2107052

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sciencedirect.com/science/article/pii/S1535610820305419