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  1. Last 7 days
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    The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies
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    sciencedirect.com/science/article/pii/S1074761324002711
  3. Jun 2024
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    Ketogenic diet administration later in life improves memory by modifying the synaptic cortical proteome via the PKA signaling pathway in aging mice
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  5. May 2024
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    1-s2.0-S2589004224013701-main-html.html
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    cell.com/iscience/abstract/S2589-0042(24)01370-1
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    hnRNPM protects against the dsRNA-mediated interferon response by repressing LINE-associated cryptic splicing
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    sciencedirect.com/science/article/pii/S1097276524003976
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    Opportunistic pathogen Porphyromonas gingivalis targets the LC3B-ceramide complex and mediates lethal mitophagy resistance in oral tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11108982/
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    Lineage-specific splicing regulation of MAPT gene in the primate brain
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    Neuroprotective effects of G9a inhibition through modulation of peroxisome-proliferator activator receptor gamma-dependent pathways by miR-128
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    Mixing energy drinks and alcohol during adolescence impairs brain function: a study of rat hippocampal plasticity
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    Beyond Glycolysis: Aldolase A is a Novel Effector in Reelin Mediated Dendritic Development
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    Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration
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    sciencedirect.com/science/article/pii/S0092867424004008
  14. Apr 2024
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    Dopamine‑iron homeostasis interaction rescues mitochondrial fitness in Parkinson's disease
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    ISG12a promotes immunotherapy of HBV-associated hepatocellular carcinoma through blocking TRIM21/AKT/β-Catenin/PD-L1 axis
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    CHD4 acts as a prognostic factor and drives radioresistance in HPV negative HNSCC
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    Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor α
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    TNFR1 mediates heterogeneity in single-cell NF-κB activation
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  20. Mar 2024
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    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
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    Cofilactin rod formation mediates inflammation-induced neurite degeneration
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    sciencedirect.com/science/article/pii/S2211124724002420
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    Uncovering the BIN1-SH3 interactome underpinning centronuclear myopathy
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      DOI: 10.7554/eLife.95397.1

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  24. Feb 2024
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    Runx2 regulates peripheral nerve regeneration to promote Schwann cell migration and re-myelination
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    Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
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    Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice
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    Dopamine-iron homeostasis interaction rescues mitochondrial fitness in Parkinson’s disease
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    Redistribution of the glycocalyx exposes phagocytic determinants on apoptotic cells
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    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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      DOI: 10.1186/s13059-023-03161-y

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  31. Jan 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigation of the functional impact of CHED- and FECD4-associated SLC4A11 mutations in human corneal endothelial cells
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    SATB2 organizes the 3D genome architecture of cognition in cortical neurons
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    FK506 bypasses the effect of erythroferrone in cancer cachexia skeletal muscle atrophy
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    Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins
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  36. www.jneurosci.org www.jneurosci.org
    Cleavage of VAMP2/3 Affects Oligodendrocyte Lineage Development in the Developing Mouse Spinal Cord
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    FOXP1 regulates the development of excitatory synaptic inputs onto striatal neurons and induces phenotypic reversal with reinstatement
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  38. Dec 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis
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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures
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      DOI: 10.3389/fnmol.2023.1323431

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  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss-of-function cancer-linked mutations in the EIF4G2 non-canonical translation initiation factor
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    ncbi.nlm.nih.gov/pmc/articles/PMC10746786/
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    ER chaperones use a protein folding and quality control glyco-code
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  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas
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      DOI: 10.1186/s40478-023-01677-9

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    Purkinje-cell-specific MeCP2 deficiency leads to motor deficits and autistic-like behavior due to aberrations in PTP1B-TrkB-SK signaling
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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Helicobacter pylori CagA promotes immune evasion of gastric cancer by upregulating PD-L1 level in exosomes
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  46. Nov 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Targeted perturbation of signaling-driven condensates
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    Lineage-specific 3D genome organization is assembled at multiple scales by IKAROS
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    Selective inhibition of CDK9 in triple negative breast cancer
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    An immunohistochemical atlas of necroptotic pathway expression
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    Loss of EIF4G2 Mediates Aggressiveness in Distinct Human Endometrial Cancer Subpopulations with Poorer Survival Outcome in Patients
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    Scn2a insufficiency alters spontaneous neuronal Ca2+ activity in somatosensory cortex during wakefulness
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    A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint
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    ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct
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  56. Sep 2023
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    Glutamate transporter contribution to retinal ganglion cell vulnerability in a rat model of multiple sclerosis
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    Essential role of the amino-terminal region of Drosha for the Microprocessor function
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    LncRNA THUMPD3-AS1 promotes invasion and EMT in gastric cancer by regulating the miR-1297/BCAT1 pathway
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  60. Aug 2023
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    Loss-of-function cancer-associated mutations in the EIF4G2 non-canonical translation initiation factor
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    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
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    Journal of Neurochemistry - 2023 - Kamte-html.html
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  64. Jul 2023
  65. www.sciencedirect.com www.sciencedirect.com
    Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
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    Loss-of-function variants in KCTD19 cause non-obstructive azoospermia in humans
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  67. Jun 2023
  68. www.biorxiv.org www.biorxiv.org
    KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss
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    Astrocytic deletion of protein kinase R-like ER kinase (PERK) does not affect learning and memory in aged mice but worsens outcome from experimental stroke
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    Temporary serine protease inhibition and the role of SPINK2 in human bone marrow
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    Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability
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    Effects of Tail Pinch on BDNF and trkB Expression in the Hippocampus of Roman Low- (RLA) and High-Avoidance (RHA) Rats
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    Arginine depletion attenuates renal cystogenesis in tuberous sclerosis complex model
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    Activity-dependent tau cleavage by caspase-3 promotes neuronal dysfunction and synaptotoxicity
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  75. aacrjournals.org aacrjournals.org
    Targeting CHAF1B enhances Interferon activity against Myeloproliferative Neoplasm cells
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  76. May 2023
  77. www.sciencedirect.com www.sciencedirect.com
    EWSR1 maintains centromere identity
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    PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-Platform Synaptic Network Analysis of Human Entorhinal Cortex Identifies TWF2 as a Modulator of Dendritic Spine Length
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    Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis
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    Inward rectifying Kir4.1 channels regulate oligodendrocyte precursor cell differentiation and CNS myelination in vivo
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    Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis
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  84. Apr 2023
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evidence for phosphorylation-dependent, dynamic, regulation of mGlu5 and Homer2 in expression of cocaine aversion in mice
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    High-content synaptic phenotyping in human cellular models reveals a role for BET proteins in synapse assembly
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    Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery
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    The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus
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    Matrix stiffness regulates tumor cell intravasation through expression and ESRP1-mediated alternative splicing of MENA
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    Affinity-ranking BIN1 interactions and screening natural BIN1 variants that may cause neuromuscular disorders
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    Endothelin-1–Endothelin receptor B complex contributes to oligodendrocyte differentiation and myelin deficits during preterm white matter injury
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  92. Mar 2023
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    HNRNPU facilitates antibody class-switch recombination through C-NHEJ promotion and R-loop suppression
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    Matrix Stiffness Induces Epithelial-to-Mesenchymal Transition Via Piezo1-Regulated Calcium Flux in Prostate Cancer Cells
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    Orai3 and Orai1 mediate CRAC channel function and metabolic reprogramming in B cells
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    Integrative Cardiovascular Physiology and Pathophysiology: Combining three independent pathological stressors induces a heart failure with preserved ejection fraction phenotype
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    Reversal of malignant ADAR1 splice isoform switching with Rebecsinib
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    Correction: Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis
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    The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
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    Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions
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    ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis
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    Loss of epigenetic information as a cause of mammalian aging
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    The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction
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    ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis
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    Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues
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    Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles
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    N-acetylglucosaminyltransferase-V (GnT-V)-enriched small extracellular vesicles mediate N-glycan remodeling in recipient cells
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    Acute Stress Induces Different Changes on the Expression of BDNF and trkB in the Mesocorticolimbic System of Two Lines of Rats Differing in Their Response to Stressors
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    Lysophosphatidic acid signaling via LPA6: a negative modulator of developmental oligodendrocyte maturation
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    Arc controls alcohol cue relapse by a central amygdala mechanism
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    MsrB1-regulated GAPDH oxidation plays programmatic roles in shaping metabolic and inflammatory signatures during macrophage activation
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    Arc controls alcohol cue relapse by a central amygdala mechanism
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    Multiphase coalescence mediates Hippo pathway activation
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  124. Oct 2022
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    Glycolaldehyde-derived advanced glycation end products suppress STING/TBK1/IRF3 signaling via CD36
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    CSF1R-mediated myeloid cell depletion prolongs lifespan but aggravates distinct motor symptoms in a model of multiple system atrophy
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  127. Sep 2022
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    The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells
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    AQP4-dependent glioma cell features affect the phenotype of surrounding cells via extracellular vesicles
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    Molecular convergence between Down syndrome and fragile X syndrome identified using human pluripotent stem cell models
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    Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction
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    The redox cycling of STAT2 maintains innate immune homeostasis
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    Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens
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    S-nitrosylation is required for β2AR desensitization and experimental asthma
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  137. Jul 2022
  138. www.nature.com www.nature.com
    LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson’s disease
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    Pannexin 2 is expressed in murine skin and promotes UVB-induced apoptosis of keratinocytes
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    Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death
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    Neuron-specific translational control shift ensures proteostatic resilience during ER stress
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  142. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Potassium channel Kir4.1 regulates oligodendrocyte differentiation via intracellular pH regulation
    1
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      DOI: 10.1002/glia.24240

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  143. Jun 2022
  144. www.sciencedirect.com www.sciencedirect.com
    Prkn knockout mice show autistic-like behaviors and aberrant synapse formation
    1
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      DOI: 10.1016/j.isci.2022.104573

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  145. www.researchsquare.com www.researchsquare.com
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      DOI: 10.21203/rs.3.rs-658360/v1

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  146. journals.lww.com journals.lww.com
    DL-3-n-butylphthalide alleviates motor disturbance by... : Neural Regeneration Research
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      DOI: 10.4103/1673-5374.343892

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  147. www.sciencedirect.com www.sciencedirect.com
    Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses
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      DOI: 10.1016/j.chembiol.2022.05.009

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  148. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuroplastic changes in c-Fos, ΔFosB, BDNF, trkB, and Arc expression in the hippocampus of male Roman rats: differential effects of sexual activity
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      DOI: 10.1002/hipo.23448

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  149. May 2022
  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development
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      DOI: 10.7554/eLife.71142

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  151. Apr 2022
  152. www.sciencedirect.com www.sciencedirect.com
    Downregulation of SATB1 by miRNAs Reduces Megakaryocyte/Erythroid Progenitor Expansion in pre-clinical models of Diamond Blackfan Anemia
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      DOI: 10.1016/j.exphem.2022.04.005

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    sciencedirect.com/science/article/pii/S0301472X22002028
  153. www.sciencedirect.com www.sciencedirect.com
    Autoantibodies against NCAM1 from patients with schizophrenia cause schizophrenia-related behavior and changes in synapses in mice
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      Merck MilliporeCat# MAB374

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    sciencedirect.com/science/article/pii/S2666379122001148
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    Heterochromatic repeat clustering imposes a physical barrier on homologous recombination to prevent chromosomal translocations
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      DOI: 10.1016/j.molcel.2022.03.033

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    Genome-wide functional perturbation of human microsatellite repeats using engineered zinc finger transcription factors
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      DOI: 10.1016/j.xgen.2022.100119

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  156. www.sciencedirect.com www.sciencedirect.com
    FER regulates endosomal recycling and is a predictor for adjuvant taxane benefit in breast cancer
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      DOI: 10.1016/j.celrep.2022.110584

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  157. Mar 2022
  158. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Endoplasmic reticulum stress is transmissible in vitro between cells of the central nervous system
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      DOI: 10.1111/jnc.14642

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  159. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Preclinical stress originates in the rat optic nerve head during development of autoimmune optic neuritis
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      DOI: 10.1002/glia.23560

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  160. www.sciencedirect.com www.sciencedirect.com
    Labeling of heterochronic ribosomes reveals C1ORF109 and SPATA5 control a late step in human ribosome assembly
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      DOI: 10.1016/j.celrep.2022.110597

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  161. www.sciencedirect.com www.sciencedirect.com
    Loss of mouse Stmn2 function causes motor neuropathy
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      DOI: 10.1016/j.neuron.2022.02.011

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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 Screens Reveal Epstein-Barr Virus Transformed B-Cell Host Dependency Factors
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      DOI: 10.1016/j.chom.2017.04.005

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    ncbi.nlm.nih.gov/pmc/articles/PMC8938989/
  163. www.sciencedirect.com www.sciencedirect.com
    Activation of the 5-HT7 receptor and MMP-9 signaling module in the hippocampal CA1 region is necessary for the development of depressive-like behavior
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      DOI: 10.1016/j.celrep.2022.110532

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  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Division of Labor between YAP and TAZ in Non–Small Cell Lung Cancer
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      DOI: 10.1158/0008-5472.CAN-20-0125

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  165. www.sciencedirect.com www.sciencedirect.com
    Recurrent evolution of an inhibitor of ESCRT-dependent virus budding and LINE-1 retrotransposition in primates
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      DOI: 10.1016/j.cub.2022.02.018

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    sciencedirect.com/science/article/pii/S0960982222002408
  166. www.sciencedirect.com www.sciencedirect.com
    Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin
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      DOI: 10.1016/j.celrep.2022.110441

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    sciencedirect.com/science/article/pii/S2211124722001681
  167. www.molbiolcell.org www.molbiolcell.org
    Pannexin 2 is expressed in murine skin and promotes UVB-induced apoptosis of keratinocytes
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      DOI: 10.1091/mbc.E21-08-0387

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    molbiolcell.org/doi/abs/10.1091/mbc.E21-08-0387
  168. Feb 2022
  169. www.sciencedirect.com www.sciencedirect.com
    BCL-XL inhibition induces an FGFR4-mediated rescue response in colorectal cancer
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    Matrix remodeling controls a nuclear lamin A/C-emerin network that directs Wnt-regulated stem cell fate
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      DOI: 10.1016/j.devcel.2022.01.015

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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KIF2C regulates synaptic plasticity and cognition in mice through dynamic microtubule depolymerization
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      DOI: 10.7554/eLife.72483

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  172. www.embopress.org www.embopress.org
    LAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function
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      RRID:AB_2107445

      DOI: 10.15252/embj.2021108119

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  173. link.springer.com link.springer.com
    CDNF and MANF regulate ER stress in a tissue-specific manner
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      DOI: 10.1007/s00018-022-04157-w

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  174. Jan 2022
  175. www.sciencedirect.com www.sciencedirect.com
    miR-376a-3p and miR-376b-3p overexpression in Hutchinson-Gilford progeria fibroblasts inhibits cell proliferation and induces premature senescence
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      DOI: 10.1016/j.isci.2022.103757

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  176. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Circadian Transcription Factor NPAS2 and the NAD+-Dependent Deacetylase SIRT1 Interact in the Mouse Nucleus Accumbens and Regulate Reward
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      RRID:AB_2107445

      DOI: 10.1111/ejn.15596

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    Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
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      DOI: 10.1016/j.cell.2021.12.041

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  178. Dec 2021
  179. www.sciencedirect.com www.sciencedirect.com
    Assessing kinetics and recruitment of DNA repair factors using high content screens
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  180. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Behavioural and neurochemical effects after repeated administration of N-ethylpentylone (ephylone) in mice
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      DOI: 10.1111/jnc.15542

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  181. academic.oup.com academic.oup.com
    Downregulation Of Dihydrotestosterone And Estradiol Levels By Hexim1
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      DOI: 10.1210/endocr/bqab236

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  182. Nov 2021
  183. 52.53.155.43 52.53.155.43
    ajpregu.00019.2021-html.html
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      RRID:AB_2107445

      DOI: 10.1152/ajpregu.00019.2021

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      DOI: 10.1152/ajpregu.00019.2021

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    52.53.155.43/aed6bd706fcd5c754b0b80eb2db9a6c5f7307ded/ajpregu.00019.2021-html.html
  184. link.springer.com link.springer.com
    Loss of SORCS2 is Associated with Neuronal DNA Double-Strand Breaks
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  185. www.sciencedirect.com www.sciencedirect.com
    Role of adipocyte Na,K-ATPase oxidant amplification loop in cognitive decline and neurodegeneration
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      DOI: 10.1016/j.isci.2021.103262

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  186. www.sciencedirect.com www.sciencedirect.com
    Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease
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      DOI: 10.1016/j.isci.2021.103327

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  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sedentary Conditions Promote Subregionally Specific Changes in Brain-Derived Neurotrophic Factor in the Rostral Ventrolateral Medulla
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      DOI: 10.3389/fphys.2021.756542

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    The Nuclear Function of IL-33 in Desensitization to DNA Damaging Agent and Change of Glioma Nuclear Structure
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    Bidirectional control of infant rat social behavior via dopaminergic innervation of the basolateral amygdala
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    DYSFUNCTION OF OLIGODENDROCYTE INWARDLY RECTIFYING POTASSIUM CHANNEL IN A RAT MODEL OF AMYOTROPHIC LATERAL SCLEROSIS
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    Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation
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    MACF1 controls skeletal muscle function through the microtubule-dependent localization of extra-synaptic myonuclei and mitochondria biogenesis
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    Nitric Oxide Induces a Janus Kinase-1-Dependent Inflammatory Response in Primary Murine Astrocytes - John D. Nowery, Rylee N. Cisney, Jacob W. Feldmann, Gordon P. Meares, 2021
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    Pharmacological Inhibition of STAT6 Ameliorates Myeloid Fibroblast Activation and Alternative Macrophage Polarization in Renal Fibrosis
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    Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease
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    The Rac-GAP alpha2-chimaerin signals via CRMP2 and stathmins in the development of the ocular motor system
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    Oxaliplatin resistance in colorectal cancer enhances TRAIL sensitivity via death receptor 4 upregulation and lipid raft localization
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    GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK
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    Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations
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    Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2
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    Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death
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    Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma
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    A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action
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