371 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vascular endothelial cells derived exosomes synergize with curcumin to prevent osteoporosis development
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    1. scibot 18 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11016789/
  3. Apr 2024
  4. 52.53.155.43 52.53.155.43
    Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1
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    Baicalein improves renal interstitial fibrosis by inhibiting the ferroptosis in vivo and in vitro
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    sciencedirect.com/science/article/pii/S2405844024049855
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    The outcome of tissue cryopreservation on cellular, molecular and epigenetic characteristics of endometrial tissue and stromal cells
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    sciencedirect.com/science/article/pii/S1472648324001792
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    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
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      DOI: 10.1016/j.stem.2024.03.003

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    sciencedirect.com/science/article/pii/S1934590924000845
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    Mitigation of inflammatory bowel disease-related osteoporosis by oxyberberine: Insights into the RANKL/NF-κB signaling pathway
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    sciencedirect.com/science/article/pii/S0753332224004074
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SGMS1 Facilitates Osteogenic Differentiation of MSCs and Strengthens Osteogenesis–Angiogenesis Coupling by Modulating Cer/PP2A/Akt Pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10966191/
  10. Mar 2024
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    Prolactin promotes the recruitment of main olfactory bulb cells and enhances the behavioral exploration toward a socio-sexual stimulus in female mice
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    sciencedirect.com/science/article/pii/S0018506X24000527
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    Effects of the Glucocorticoid-Mediated Mitochondrial Translocation of Glucocorticoid Receptors on Oxidative Stress and Pyroptosis in BV-2 Microglia
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    link.springer.com/article/10.1007/s12031-024-02192-9
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    Impaired oxysterol-liver X receptor signaling underlies aberrant cortical neurogenesis in a stem cell model of neurodevelopmental disorder
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    sciencedirect.com/science/article/pii/S2211124724002742
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    An early cell shape transition drives evolutionary expansion of the human forebrain
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    1. scibot 08 Mar 2024
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    sciencedirect.com/science/article/pii/S0092867421002397
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    OPA1 mediates muscle differentiation by promoting a metabolic switch via the supercomplex assembly factor SCAF1
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    1. scibot 07 Mar 2024
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    sciencedirect.com/science/article/pii/S2589004224003857
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    Cellular senescence is associated with the spatial evolution toward a higher metastatic phenotype in colorectal cancer
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    sciencedirect.com/science/article/pii/S2211124724002407
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    PDGFRα+ITGA11+ fibroblasts foster early-stage cancer lymphovascular invasion and lymphatic metastasis via ITGA11-SELE interplay
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    sciencedirect.com/science/article/pii/S1535610824000461
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    Triaging of α-helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology
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    sciencedirect.com/science/article/pii/S1097276524000959
  19. Feb 2024
  20. www.sciencedirect.com www.sciencedirect.com
    YAP mediates apoptosis through failed integrin adhesion reinforcement
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    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113811

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    sciencedirect.com/science/article/pii/S2211124724001396
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    Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Radix Paeoniae Rubra Against Glioma
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      DOI: 10.1007/s12010-024-04887-6

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    link.springer.com/article/10.1007/s12010-024-04887-6
  22. www.sciencedirect.com www.sciencedirect.com
    Trichinella spiralis inhibits myoblast differentiation by targeting SQSTM1/p62 with a secreted E3 ubiquitin ligase
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    sciencedirect.com/science/article/pii/S2589004224003237
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The liver and muscle secreted HFE2-protein maintains central nervous system blood vessel integrity
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      DOI: 10.1038/s41467-024-45303-1

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    DPCD is a regulator of R2TP in ciliogenesis initiation through Akt signaling
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    sciencedirect.com/science/article/pii/S221112472400041X
  25. Jan 2024
  26. onlinelibrary.wiley.com onlinelibrary.wiley.com
    IP3RPEP6, a novel peptide inhibitor of IP3 receptor channels that does not affect connexin-43 hemichannels
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    1. scibot 26 Jan 2024
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      DOI: 10.1111/apha.14086

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    onlinelibrary.wiley.com/doi/10.1111/apha.14086
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    circGlis3 promotes β-cell dysfunction by inhibiting hnRNPF nuclear translocation and encoding Glis3-348aa protein
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      DOI: 10.1016/j.isci.2023.108680

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    ncbi.nlm.nih.gov/pmc/articles/PMC10788204/
  28. link.springer.com link.springer.com
    Disparate macrophage responses are linked to infection outcome of Hantan virus in humans or rodents
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      DOI: 10.1038/s41467-024-44687-4

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    link.springer.com/article/10.1038/s41467-024-44687-4
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acute exposure of microwave impairs attention process by activating microglial inflammation
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      DOI: 10.1186/s13578-023-01162-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10768366/
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    Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway
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      DOI: 10.1016/j.molcel.2023.12.012

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    sciencedirect.com/science/article/pii/S1097276523010328
  31. Dec 2023
  32. elifesciences.org elifesciences.org
    Rab12 is a regulator of LRRK2 and its activation by damaged lysosomes
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      DOI: 10.7554/eLife.87255

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    elifesciences.org/articles/87255
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cyclophilin A facilitates influenza B virus replication by stabilizing viral proteins
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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology
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      DOI: 10.1007/s00018-022-04378-z

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  35. Nov 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
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      DOI: 10.1186/s40779-023-00494-4

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    Blockade of CCR5 suppresses paclitaxel-induced peripheral neuropathic pain caused by increased deoxycholic acid
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    Sbp2l contributes to oligodendrocyte maturation through translational control in Tcf7l2 signaling
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    sciencedirect.com/science/article/pii/S2589004223025282
  39. 52.53.155.43 52.53.155.43
    ABHD12 contributes to tumorigenesis and sorafenib resistance by preventing ferroptosis in hepatocellular carcinoma
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      DOI: 10.1016/j.isci.2023.108340

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    Exosomes derived from platelet-rich plasma promote diabetic wound healing via the JAK2/STAT3 pathway
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      DOI: 10.1016/j.isci.2023.108236

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    sciencedirect.com/science/article/pii/S2589004223023131
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons
    2
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      DOI: 10.1016/j.isci.2023.108152

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      DOI: 10.1016/j.isci.2023.108152

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  42. Oct 2023
  43. www.science.org www.science.org
    Piezo1 activates noncanonical EGFR endocytosis and signaling
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      DOI: 10.1126/sciadv.adi1328

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  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy
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    Circ_0000888 regulates osteogenic differentiation of periosteal mesenchymal stem cells in congenital pseudarthrosis of the tibia
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  46. 52.53.155.43 52.53.155.43
    PIIS2211124723012159-html.html
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  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Piezo1 activates noncanonical EGFR endocytosis and signaling
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  48. Sep 2023
  49. dx.doi.org dx.doi.org
    Protective effects of low-intensity pulsed ultrasound (LIPUS) against cerebral ischemic stroke in mice by promoting brain vascular remodeling via the inhibition of ROCK1/p-MLC2 signaling pathway
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    Inducible nitric oxide synthase activity mediates TNF-α-induced endothelial cell dysfunction
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    LSR targets YAP to modulate intestinal Paneth cell differentiation
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    Mammalian autophagosomes form from finger-like phagophores
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    Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection
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    Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling
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    Colonic phosphocholine is correlated with Candida tropicalis and promotes diarrhea and pathogen clearance
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  56. Aug 2023
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long-term safety and dose escalation of intracerebroventricular CLN5 gene therapy in sheep supports clinical translation for CLN5 Batten disease
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    The Achromobacter type 3 secretion system drives pyroptosis and immunopathology via independent activation of NLRC4 and NLRP3 inflammasomes
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    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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    Kappa opioid receptor in nucleus accumbens regulates depressive-like behaviors following prolonged morphine withdrawal in mice
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    PROTAC targeting cyclophilin A controls virus-induced cytokine storm
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    Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1
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    Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
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  64. Jul 2023
  65. www.sciencedirect.com www.sciencedirect.com
    The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina
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    A consequence of immature breathing induces persistent changes in hippocampal synaptic plasticity and behavior: a role of prooxidant state and NMDA receptor imbalance
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  67. 52.53.155.43 52.53.155.43
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  68. Jun 2023
  69. www.sciencedirect.com www.sciencedirect.com
    Resistin targets TAZ to promote osteogenic differentiation through PI3K/AKT/mTOR pathway
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    ArhGAP11A mediates amyloid-β generation and neuropathology in an Alzheimer’s disease-like mouse model
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    Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1
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    Macrophage-derived cathepsin S remodels the extracellular matrix to promote liver fibrogenesis
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  73. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Investigating the effects of 7-ketocholesterol on retinal pigment epithelium bioenergetics
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    SPI1 Regulates the Progression of Ankylosing Spondylitis by Modulating TLR5 via NF-κB Signaling
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  75. May 2023
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    General trends in the effects of VX-661 and VX-445 on the plasma membrane expression of clinical CFTR variants
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    Activation of endoplasmic reticulum stress in premature aging via the inner nuclear membrane protein SUN2
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    Metamorphic proteins at the basis of human autophagy initiation and lipid transfer
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    Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin
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    Age-Related Changes in the Primary Motor Cortex of Newborn to Adult Domestic Pig Sus scrofa domesticus
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    Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
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    The sinusoidal hematopoietic niche is formed by Jam1a via Notch signaling in the zebrafish kidney
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  83. Apr 2023
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    CD142 Identifies Neoplastic Desmoid Tumor Cells, Uncovering Interactions Between Neoplastic and Stromal Cells That Drive Proliferation
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    Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration
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    A tubule-sheet continuum model for the mechanism of nuclear envelope assembly
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    Unidirectional and phase-gated signaling synchronizes murine presomitic mesoderm cells
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    A Consequence of Immature Breathing induces Persistent Changes in Hippocampal Synaptic Plasticity and Behavior: A Role of Pro-Oxidant State and NMDA Receptor Imbalance
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    MrgprA3-expressing pruriceptors drive pruritogen-induced alloknesis through mechanosensitive Piezo2 channel
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    The SOAR of STIM1 interacts with plasma membrane lipids to form ER-PM contact sites
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    Non-Coding RNAs in Cell Physiology: Manipulation of the miR-378a/mt-ATP6 regulatory axis rescues ATP synthase in the diabetic heart and offers a novel role for lncRNA Kcnq1ot1
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    Integrative Single-Cell Analysis Reveals Transcriptional and Epigenetic Regulatory Features of Clear Cell Renal Cell Carcinoma
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    The effect of KTKEGV repeat motif and intervening ATVA sequence on α-synuclein solubility and assembly
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    Loss of C9orf72 perturbs the Ran-GTPase gradient and nucleocytoplasmic transport, generating compositionally diverse Importin β-1 granules
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    Isoflurane Postconditioning Alleviates Ischemic Neuronal Injury via MiR-384-5p Regulated Autophagy
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    Knockdown of disheveled-associated activator of morphogenesis 2 disrupts cytoskeletal organization and phagocytosis in rat Sertoli cells
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    Establishment and characterization of immortalized human vocal fold fibroblast cell lines
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    Time-dependent and selective microglia-mediated removal of spinal synapses in neuropathic pain
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    Genotypic and phenotypic spectrum and pathogenesis of WNT1 variants in a large cohort of patients with OI/osteoporosis
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    Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome
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    Cystatin B deficiency results in sustained histone H3 tail cleavage in postnatal mouse brain mediated by increased chromatin-associated cathepsin L activity
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    RNA degradation eliminates developmental transcripts during murine embryonic stem cell differentiation via CAPRIN1-XRN2
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    Organoid modeling of human fetal lung alveolar development reveals mechanisms of cell fate patterning and neonatal respiratory disease
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    CD206+/MHCII− macrophage accumulation at nerve injury site correlates with attenuation of allodynia in TASTPM mouse model of Alzheimer's disease
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    MARK2 and MARK4 regulate Sertoli cell BTB dynamics through microtubule and actin cytoskeletons
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    Systems analysis of de novo mutations in congenital heart diseases identified a protein network in the hypoplastic left heart syndrome
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    Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages
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    FYN regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization via its effect on Arp3 in the mouse testis
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    Knockdown of Acid-sensing Ion Channel 1a in the PVN Promotes Metabolic Disturbances in Male Mice
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    The mitochondrial protein OPA1 regulates the quiescent state of adult muscle stem cells
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    Tripartite Motif 38 Attenuates Cardiac Fibrosis after Myocardial Infarction by Suppressing TAK1 Activation via TAB2/3 Degradation
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    Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance
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  136. Jul 2022
  137. yc.mlpla.mil.cn yc.mlpla.mil.cn
    Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells
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    Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover
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    Inhibition of DYRK1A, via histone modification, promotes cardiomyocyte cell cycle activation and cardiac repair after myocardial infarction
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  140. Jun 2022
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    Pro-α-cell-derived β-cells contribute to β-cell neogenesis induced by antagonistic glucagon receptor antibody in type 2 diabetic mice
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  142. journals.lww.com journals.lww.com
    Muse cells decrease the neuroinflammatory response by... : Neural Regeneration Research
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    Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology
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    MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression
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    Construction of tissue-engineered nucleus pulposus by stimulation with periodic mechanical stress and BMP-2
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  146. May 2022
  147. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging Alters the Formation and Functionality of Signaling Microdomains Between L-type Calcium Channels and β2-Adrenergic Receptors in Cardiac Pacemaker Cells
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    Glycine decarboxylase maintains mitochondrial protein lipoylation to support tumor growth
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  150. Apr 2022
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    miRNA/mRNA co-profiling identifies the miR-200 family as a central regulator of SMC quiescence
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  152. journals.physiology.org journals.physiology.org
    Manipulation of the miR-378a/mt-ATP6 regulatory axis rescues ATP synthase in the diabetic heart and offers a novel role for lncRNA Kcnq1ot1
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    Extracellular tau oligomers affect extracellular glutamate handling by astrocytes through downregulation of GLT-1 expression and impairment of NKA1A2 function
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    Cholesterol suppresses GOLM1-dependent selective autophagy of RTKs in hepatocellular carcinoma
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    ACTL6a coordinates axonal caliber recognition and myelination in the peripheral nerve.
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    Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model
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    A clinically relevant heterozygous ATR mutation sensitizes colorectal cancer cells to replication stress
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  158. Mar 2022
  159. www.sciencedirect.com www.sciencedirect.com
    Delicate regulation of IL-1β-mediated inflammation by cyclophilin A
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    Involvement of CCN1 Protein and TLR2/4 Signaling Pathways in Intestinal Epithelial Cells Response to Listeria monocytogenes
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    Endothelial cells promote the proliferation and migration of Schwann cells
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    PCP protein inversin regulates testis function through changes in cytoskeletal organization of actin and microtubules
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  163. Jan 2022
  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular Investigation of the Unfolded Protein Response in Select Human Tauopathies
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    Enrichment of SARM1 alleles encoding variants with constitutively hyperactive NADase in patients with ALS and other motor nerve disorders
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    16pdel lipid changes in iPSC-derived neurons and function of FAM57B in lipid metabolism and synaptogenesis
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  167. Dec 2021
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    Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells
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    SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response
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    Circ_0000518 promotes macrophage/microglia M1 polarization via the FUS/CaMKKβ/AMPK pathway to aggravate multiple sclerosis
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  172. Nov 2021
  173. 52.53.155.43 52.53.155.43
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    A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy
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  175. Oct 2021
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    Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation
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    Regulation of electrogenic Na+/HCO3− cotransporter 1 (NBCe1) function and its dependence on m-TOR mediated phosphorylation of Ser245
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    Interleukin-6 Promotes Microtubule Stability in Axons via Stat3 Protein-Protein Interactions
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    Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation
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  180. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    AKAP9 supports spermatogenesis through its effects on microtubule and actin cytoskeletons in the rat testis
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    HIV-1 establishes a sanctuary site in the testis by permeating the BTB through changes in cytoskeletal organization
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  182. Sep 2021
  183. www.sciencedirect.com www.sciencedirect.com
    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
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      DOI: 10.1016/j.devcel.2021.09.001

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    Inappropriate use of antibiotics exacerbates inflammation through OMV-induced pyroptosis in MDR Klebsiella pneumoniae infection
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    Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice
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  186. Aug 2021
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    The Amot/integrin protein complex transmits mechanical forces required for vascular expansion
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    The non-muscle ADF/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of blood-testis barrier dynamics by the mTORC1/rpS6 signaling complex: an in vitro study
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  191. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    Pen-2 negatively regulates the differentiation of oligodendrocyte precursor cells into astrocytes in the central nervous system
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  199. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cannabinoid Receptor 1 associates to different molecular complexes during GABAergic neuron maturation
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  200. onlinelibrary.wiley.com onlinelibrary.wiley.com
    NC1‐peptide regulates spermatogenesis through changes in cytoskeletal organization mediated by EB1
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  205. Jul 2021
  206. academic.oup.com academic.oup.com
    F5-peptide and mTORC1/rpS6 effectively enhance BTB transport function in the testis – lesson from the adjudin model
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  208. onlinelibrary.wiley.com onlinelibrary.wiley.com
    NC1‐peptide regulates spermatogenesis through changes in cytoskeletal organization mediated by EB1
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    ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures
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    Tanshinone IIA Restores Dynamic Balance of Autophagosome/Autolysosome in Doxorubicin-Induced Cardiotoxicity via Targeting Beclin1/LAMP1
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      anti-GAPDH

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    Repetitive Diffuse Mild Traumatic Brain Injury Causes an Atypical Astrocyte Response and Spontaneous Recurrent Seizures
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    Myosin VIIa Supports Spermatid/Organelle Transport and Cell Adhesion During Spermatogenesis in the Rat Testis
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  214. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  215. www.jneurosci.org www.jneurosci.org
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  216. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sustained activation of ERK1/2 MAPK in Schwann cells causes corneal neurofibroma
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