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    Discovery and preclinical validation of a translationally optimized mitochondrial complex I modulator for Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC13538682/
  3. Jul 2026
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    KRAS-mediated CCDC6 degradation drives xCT upregulation and ferroptosis evasion
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  5. Jun 2026
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    Overcoming ADC resistance in advanced colorectal cancer by dual targeting of TROP2 and PERK to suppress Wnt/β-catenin signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13198297/
  7. May 2026
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    It’s Not Rewarding for Mitochondria: Dopamine-Induced Mitochondrial Dysfunction Activates cGAS-STING to Drive IL-6 Secretion in Macrophages
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    biorxiv.org/content/10.64898/2026.04.23.719926v1
  10. Apr 2026
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    Discovery and Preclinical Validation of a Clinically Optimized Mitochondrial Complex I Modulator for Alzheimer’s Disease
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  13. Feb 2026
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    Repressed mTORC1 signaling and transient dendritic pruning support axonal regeneration
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  16. Jan 2026
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    Endometrial stromal cell-derived TMAO sustains decidualization to prevent recurrent spontaneous abortion
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  21. Oct 2025
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    Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma
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  23. Sep 2025
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    Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer's disease
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  25. Jun 2025
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    Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer’s disease
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  29. Feb 2025
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    TGF-β1-mediated intercellular signaling fuels cooperative cellular invasion
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  31. Jan 2025
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    Neuraminidase 1 regulates neuropathogenesis by governing the cellular state of microglia via modulation of Trem2 sialylation
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  33. Sep 2024
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    IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis
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    Cancer cell stiffening via CoQ10 and UBIAD1 regulates ECM signaling and ferroptosis in breast cancer
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  36. Aug 2024
  37. elifesciences.org elifesciences.org
    Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling
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  38. Jul 2023
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    mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching
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  40. Apr 2023
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    Deletion of the tyrosine phosphatase Shp2 in cervical cancer cells promotes reprogramming of glutamine metabolism
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    Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice
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    Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness
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  44. Jan 2023
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    Immune checkpoint HLA-E:CD94-NKG2A mediates evasion of circulating tumor cells from NK cell surveillance
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    CDK1 bridges NF-κB and β-catenin signaling in response to H. pylori infection in gastric tumorigenesis
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  47. Jun 2022
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    Icariin ameliorates memory deficits through regulating... : Neural Regeneration Research
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    Genetic screens identify a context-specific PI3K/p27Kip1 node driving extrahepatic biliary cancer
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  50. May 2022
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    c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity
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  52. Aug 2021
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    An extensive and dynamic trans-omic network illustrating prominent regulatory mechanisms in response to insulin in the liver
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    Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
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    Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and postabsorptive responses of mice in an age-dependent manner
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    physiology.org/doi/abs/10.1152/ajpendo.00496.2018
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  58. Jul 2021
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    Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis
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    PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling
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  62. Jan 2021
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    Schistosoma mansoni eggs induce Wnt/β-catenin signaling and activate the protooncogene c-Jun in human and hamster colon
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  64. Nov 2020
  65. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Effect of Hyperbaric Oxygen Therapy on Acute Liver Injury and Survival in a Rat Cecal Slurry Peritonitis Model
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    The potential use of tideglusib as an adjuvant radio-therapeutic treatment for glioblastoma multiforme cancer stem-like cells
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    link.springer.com/article/10.1007/s43440-020-00180-5
  67. Oct 2020
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    Tideglusib attenuates growth of neuroblastoma cancer stem/progenitor cells in vitro and in vivo by specifically targeting GSK-3β
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  70. Sep 2020
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    A novel compound DBZ ameliorates neuroinflammation in LPS-stimulated microglia and ischemic stroke rats: Role of Akt(Ser473)/GSK3β(Ser9)-mediated Nrf2 activation
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    Gut hormone GIP induces inflammation and insulin resistance in the hypothalamus
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    Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination
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  74. Jan 2020
  75. academic.oup.com academic.oup.com
    Chronic light cycle-disruption alters central insulin and leptin signalling as well as metabolic markers in male mice
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    N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil-Targeting FBXW7 Tumor Suppressor
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    Activation of GSK3β induced by recall of cocaine reward memories is dependent on GluN2A/B NMDA receptor signaling
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    Diosmetin induces apoptosis and enhances the chemotherapeutic efficacy of paclitaxel in non‐small cell lung cancer cells via Nrf2 inhibition
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  80. Nov 2018
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    Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling
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    In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver
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    Maternal separation stress reduced prenatal-ethanol-induced increase in exploratory behaviour and extracellular signal-regulated kinase activity
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    Maternal exercise modifies body composition and energy substrates handling in high‐fat/high‐sucrose diet fed male offspring
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  86. Nov 2017
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    Heparan sulfate alterations in extracellular matrix structures and fibroblast growth factor‐2 signaling impairment in the aged neurogenic niche
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    Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells
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    Early ethanol exposure and vinpocetine treatment alter learning‐ and memory‐related proteins in the rat hippocampus and prefrontal cortex
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    Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling
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    Mice lacking circadian clock components display different mood-related behaviors and do not respond uniformly to chronic lithium treatment: Chronobiology International: Vol 32, No 8
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