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Oct 2026
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Dopamine-induced mitochondrial dysfunction activates cGAS-sTING to drive IL-6 secretion in macrophages

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Repressed mTORC1 signaling and transient dendritic pruning support axonal regeneration in adult zebrafish

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Sep 2026
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Discovery and preclinical validation of a translationally optimized mitochondrial complex I modulator for Alzheimer’s disease

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Jul 2026
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KRAS-mediated CCDC6 degradation drives xCT upregulation and ferroptosis evasion

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pmc.ncbi.nlm.nih.gov/articles/PMC13369686/
Jun 2026
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Overcoming ADC resistance in advanced colorectal cancer by dual targeting of TROP2 and PERK to suppress Wnt/β-catenin signaling

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pmc.ncbi.nlm.nih.gov/articles/PMC13198297/
May 2026
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BPS Publications

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It’s Not Rewarding for Mitochondria: Dopamine-Induced Mitochondrial Dysfunction Activates cGAS-STING to Drive IL-6 Secretion in Macrophages

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biorxiv.org/content/10.64898/2026.04.23.719926v1
Apr 2026
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Discovery and Preclinical Validation of a Clinically Optimized Mitochondrial Complex I Modulator for Alzheimer’s Disease

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BPS Publications

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Feb 2026
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1-s2.0-S0014488626000488-main-html.html

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Repressed mTORC1 signaling and transient dendritic pruning support axonal regeneration

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Jan 2026
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Endometrial stromal cell-derived TMAO sustains decidualization to prevent recurrent spontaneous abortion

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Dec 2025
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1-s2.0-S2589004225026409-main-html.html

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1-s2.0-S2589004225025532-main-html.html

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54.241.53.176/5d87d160757da073ce52ccfdd6f8180fdf9242bd/1-s2.0-S2589004225025532-main-html.html
Oct 2025
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Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma

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pmc.ncbi.nlm.nih.gov/articles/PMC12500318/
Sep 2025
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Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer's disease

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sciencedirect.com/science/article/pii/S2352396425003688
Jun 2025
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Mar 2025
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Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer’s disease

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Feb 2025
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TGF-β1-mediated intercellular signaling fuels cooperative cellular invasion

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Jan 2025
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Neuraminidase 1 regulates neuropathogenesis by governing the cellular state of microglia via modulation of Trem2 sialylation

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Sep 2024
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IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis

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Cancer cell stiffening via CoQ10 and UBIAD1 regulates ECM signaling and ferroptosis in breast cancer

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Aug 2024
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Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling

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elifesciences.org/content/5/e17047
Jul 2023
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mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching

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Apr 2023
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Deletion of the tyrosine phosphatase Shp2 in cervical cancer cells promotes reprogramming of glutamine metabolism

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Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice

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Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness

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Jan 2023
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Immune checkpoint HLA-E:CD94-NKG2A mediates evasion of circulating tumor cells from NK cell surveillance

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CDK1 bridges NF-κB and β-catenin signaling in response to H. pylori infection in gastric tumorigenesis

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Jun 2022
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Icariin ameliorates memory deficits through regulating... : Neural Regeneration Research

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Genetic screens identify a context-specific PI3K/p27Kip1 node driving extrahepatic biliary cancer

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ncbi.nlm.nih.gov/pmc/articles/PMC7612573/
May 2022
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c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity

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Aug 2021
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An extensive and dynamic trans-omic network illustrating prominent regulatory mechanisms in response to insulin in the liver

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Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines

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Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and postabsorptive responses of mice in an age-dependent manner

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Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis

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BPS Publications

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PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling

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Schistosoma mansoni eggs induce Wnt/β-catenin signaling and activate the protooncogene c-Jun in human and hamster colon

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Effect of Hyperbaric Oxygen Therapy on Acute Liver Injury and Survival in a Rat Cecal Slurry Peritonitis Model

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The potential use of tideglusib as an adjuvant radio-therapeutic treatment for glioblastoma multiforme cancer stem-like cells

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  phosphorylated GSK-3β
  
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Tideglusib attenuates growth of neuroblastoma cancer stem/progenitor cells in vitro and in vivo by specifically targeting GSK-3β

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BPS Publications

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A novel compound DBZ ameliorates neuroinflammation in LPS-stimulated microglia and ischemic stroke rats: Role of Akt(Ser473)/GSK3β(Ser9)-mediated Nrf2 activation

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Gut hormone GIP induces inflammation and insulin resistance in the hypothalamus

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Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination

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Chronic light cycle-disruption alters central insulin and leptin signalling as well as metabolic markers in male mice

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N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil-Targeting FBXW7 Tumor Suppressor

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Activation of GSK3β induced by recall of cocaine reward memories is dependent on GluN2A/B NMDA receptor signaling

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Untitled document

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Diosmetin induces apoptosis and enhances the chemotherapeutic efficacy of paclitaxel in non‐small cell lung cancer cells via Nrf2 inhibition

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Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling

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In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver

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Maternal separation stress reduced prenatal-ethanol-induced increase in exploratory behaviour and extracellular signal-regulated kinase activity

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Maternal exercise modifies body composition and energy substrates handling in high‐fat/high‐sucrose diet fed male offspring

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onlinelibrary.wiley.com/doi/10.1113/JP274739/full
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Heparan sulfate alterations in extracellular matrix structures and fibroblast growth factor‐2 signaling impairment in the aged neurogenic niche

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Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells

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Early ethanol exposure and vinpocetine treatment alter learning‐ and memory‐related proteins in the rat hippocampus and prefrontal cortex

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Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling

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Mice lacking circadian clock components display different mood-related behaviors and do not respond uniformly to chronic lithium treatment: Chronobiology International: Vol 32, No 8

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