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Migrasome-mediated clearance of excess PLK4 defines a targetable vulnerability

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1. scibot 07 Apr 2026
  
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  DOI: 10.1016/j.ebiom.2026.106237
  
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thelancet.com/journals/ebiom/article/PIIS2352-3964(26)00119-2/fulltext
Mar 2026
onlinelibrary.wiley.com onlinelibrary.wiley.com

Young Regulatory T Cell-Derived Extracellular Vesicles Improve Mitochondrial Function and Angiogenesis and Suppress Inflammation in Senescent Brain and Heart

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1. scibot 19 Mar 2026
  
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  DOI: 10.1111/jnc.70402
  
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onlinelibrary.wiley.com/doi/full/10.1111/jnc.70402
Feb 2026
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A high-resolution, easy-to-build light-sheet microscope for subcellular imaging

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1. scibot 07 Feb 2026
  
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  DOI: 10.7554/eLife.106910
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12875610/
Jan 2026
54.241.53.176 54.241.53.176

2026.01.01.697161v1.full-html.html

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  DOI: 10.64898/2026.01.01.697161
  
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54.241.53.176/ffadff401656d9d116040b3f55c1d0047a810d2e/2026.01.01.697161v1.full-html.html
Jul 2025
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TBK1 phagosomal recruitment enhances antifungal immunity via positive feedback regulation with SRC

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  DOI: 10.1016/j.celrep.2025.115972
  
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cell.com/cell-reports/abstract/S2211-1247(25)00743-0
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TM9SF3 is a Golgi-resident ATG8-binding protein essential for Golgi-selective autophagy

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  DOI: 10.1016/j.devcel.2025.06.017
  
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sciencedirect.com/science/article/pii/S1534580725003727
Jun 2025
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Arachidonic acid triggers spermidine synthase secretion from primary tumor to induce skeletal muscle weakness upon irradiation

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.cmet.2025.05.013
  
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sciencedirect.com/science/article/pii/S1550413125002694
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DMXL1 promotes recruitment of V1-ATPase to lysosomes upon TRPML1 activation

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  DOI: 10.1038/s41594-025-01581-x
  
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nature.com/articles/s41594-025-01581-x
May 2025
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DDX5 super-enhancer promotes vasculogenic mimicry formation and metastasis in nasopharyngeal carcinoma by enhancing ADAM10 transcription

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  DOI: 10.1016/j.xcrm.2025.102146
  
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sciencedirect.com/science/article/pii/S2666379125002198
Apr 2025
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Aberrant phase separation drives membranous organelle remodeling and tumorigenesis

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  DOI: 10.1016/j.molcel.2025.04.001
  
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sciencedirect.com/science/article/pii/S1097276525003041
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ARMC1 partitions between distinct complexes and assembles MIRO with MTFR to control mitochondrial distribution

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1. scibot 16 Apr 2025
  
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  DOI: 10.1126/sciadv.adu5091
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11980836/
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ARMC1 partitions between distinct complexes and assembles MIRO with MTFR to control mitochondrial distribution

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  DOI: 10.1126/sciadv.adu5091
  
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science.org/doi/10.1126/sciadv.adu5091
Mar 2025
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VIPAS39 confers ferroptosis resistance in epithelial ovarian cancer through exporting ACSL4

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.ebiom.2025.105646
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11957506/
Feb 2025
52.53.155.43 52.53.155.43

PDF-html.html

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  DOI: 10.1158/0008-5472.can-24-1893
  
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52.53.155.43/687be9d2d25c48928f609b8bb1a6c7ac601f5d4d/PDF-html.html
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

VPS13B is localized at the interface between Golgi cisternae and is a functional partner of FAM177A1

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1. scibot 08 Oct 2024
  
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  DOI: 10.1083/jcb.202311189
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11451052/
May 2024
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Spatiotemporal proteomic profiling of cellular responses to NLRP3 agonists

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1. scibot 01 May 2024
  
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  DOI: 10.1101/2024.04.19.590338
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11042255/
Apr 2024
www.ahajournals.org www.ahajournals.org

New Loss-of-Function Mutations in PCSK9 Reduce Plasma LDL Cholesterol

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1. scibot 18 Apr 2024
  
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  DOI: 10.1161/ATVBAHA.122.318839
  
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ahajournals.org/doi/10.1161/ATVBAHA.122.318839
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New Loss-of-Function Mutations in PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Reduce Plasma LDL (Low-Density Lipoprotein) Cholesterol

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1. scibot 04 Apr 2024
  
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  DOI: 10.1161/ATVBAHA.122.318839
  
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ahajournals.org/doi/abs/10.1161/ATVBAHA.122.318839
Feb 2024
52.53.155.43 52.53.155.43

meng-et-al-2023-new-loss-of-function-mutations-in-pcsk9-reduce-plasma-ldl-cholesterol-html.html

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  DOI: 10.1161/atvbaha.122.318839
  
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52.53.155.43/6dc7bb5c3defb3dc565dda6223aa90187b2786e1/meng-et-al-2023-new-loss-of-function-mutations-in-pcsk9-reduce-plasma-ldl-cholesterol-html.html
Dec 2023
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Isolation and characterization of small extracellular vesicles from murine primary mammary tumor

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  DOI: 10.1016/j.xpro.2023.102783
  
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sciencedirect.com/science/article/pii/S2666166723007505
Oct 2023
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Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer

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  DOI: 10.1016/j.celrep.2023.113270
  
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sciencedirect.com/science/article/pii/S2211124723012822
Jul 2023
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The kinesin Kif21b regulates radial migration of cortical projection neurons through a non-canonical function on actin cytoskeleton

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  DOI: 10.1016/j.celrep.2023.112744
  
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sciencedirect.com/science/article/pii/S2211124723007556
Jun 2023
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The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity

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  DOI: 10.1016/j.immuni.2023.06.002
  
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sciencedirect.com/science/article/pii/S1074761323002376
May 2023
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ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy

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  DOI: 10.1038/s41467-023-38605-3
  
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nature.com/articles/s41467-023-38605-3
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Exercise-derived peptide protects against pathological cardiac remodeling

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  DOI: 10.1016/j.ebiom.2022.104164
  
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sciencedirect.com/science/article/pii/S2352396422003450
Jan 2023
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Electrical signals in the ER are cell type and stimulus specific with extreme spatial compartmentalization in neurons

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  DOI: 10.1016/j.celrep.2022.111943
  
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sciencedirect.com/science/article/pii/S2211124722018447
Dec 2022
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MOSPD2 is an endoplasmic reticulum–lipid droplet tether functioning in LD homeostasis

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  DOI: 10.1083/jcb.202110044
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8996327/
Oct 2022
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TissUExM enables quantitative ultrastructural analysis in whole vertebrate embryos by expansion microscopy

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  DOI: 10.1016/j.crmeth.2022.100311
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9606133/
Jul 2021
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An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress

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  DOI: 10.1016/j.molcel.2021.06.017
  
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sciencedirect.com/science/article/pii/S1097276521004974
May 2021
www.cell.com www.cell.com

TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis

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  Rabbit anti-GM130
  
  DOI: 10.1016/j.cmet.2021.05.006
  
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cell.com/cell-metabolism/fulltext/S1550-4131(21)00223-0
Apr 2021
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Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans

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  DOI: 10.1016/j.cmet.2020.10.020
  
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sciencedirect.com/science/article/pii/S1550413120305532
Nov 2018
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Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1074761318303844
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A Golgi Lipid Signaling Pathway Controls Apical Golgi Distribution and Cell Polarity during Neurogenesis

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1534580718301576